Selenium Supplementation in Rheumatoid Arthritis: Evidence from Controlled Clinical Trials and Mechanistic Insights
Abstract
730 1645
Selenium Supplementation in Rheumatoid Arthritis: Evidence from Controlled Clinical Trials and Mechanistic InsightsAbstract
Selenium (Se) is a key micronutrient integrated into selenoproteins such as glutathione peroxidases (GPx), which are responsible for crucial antioxidant and anti-inflammatory mechanisms. Oxidative stress contributes to the immunopathogenesis and chronic joint damage of rheumatoid arthritis (RA), supporting interest in selenium supplementation as an adjunct therapeutic strategy. This review was based on a structured literature search of major biomedical databases and evaluated six controlled clinical trials involvin [...] 730 1645 |
Wind Turbine Tower Structural and Cost Optimisation within Acceptable Structural Integrityby
Abstract
As the demand for cleaner-greener energy surges owing to more nations adopting Net Zero Emission by 2050, wind turbine (WT) technology is increasingly poised as one of the technologies to match the demand. Capacity building in the development of cost-effective WT tower with improved reliability and safety has become critical to delivering Net Zero mandate. This research demonstrates implementation of Taguchi Design of Experiment (DoE) in conjunction with Signal-to-noise ratio (S/N) to optimise both structural desig [...] 451 1549 |
Compassionate Mind Training for All: An Evaluation of a One-Day Compassionate Mind Training Workshop for Mental Health NHS Staff as Part of Compassion Focused Staff SupportAbstract
It has become increasingly evident that individuals who work in the NHS can be heavily impacted by the nature of their work; for instance, PTSD, work related burnout, vicarious trauma, moral injury, anxiety, and depression. In turn, individuals who experience said psychological difficulties often require work-related mental health leave from work. This paper examines the experience of a One-day Compassionate Mind Training workshop (CMT), available for all NHS staff. This day has an emphasis on developing multidirec [...] 455 1537 |
Photocatalytic and Catalytic Methods for Organic Azo Dyes and Paranitrophenol Pollutants Removal Using Green Synthesised Flacourtia indica Silver NanoparticlesAbstract
The advancement of photocatalytic nanomaterials has become central to addressing the growing challenge of removing organic pollutants from water systems through sustainable and efficient degradation pathways. In this study, silver nanoparticles were synthesized via a green approach using aqueous extracts derived from five parts of Flacourtia indica, including bark, flower, fruit, seed, and leaves, at 90°C for 45 minutes. UV–VIS spectroscopy (460 nm) confirmed nanoparticle formation, while scanning electron microsco [...] 497 1326 |
Nutrition and Transplant OutcomesAbstract
Dietary guidelines and Nutrient Reference Intakes are important tools for maintaining optimal health in the general population. Similar guidelines have also been developed by specific organ health associations to help their patient populations recover from disorders or prevent/delay clinical events and subsequent complications. However, there are no specific national and international guidelines to provide dietary and nutrient intake recommendations peri-transplantation. The complex nature of transplantation and in [...] 317 756 |
The Impact of Governmental and Workplace Measures on the Employment Sustainability of Chronically Ill IndividualsAbstract
Using a two-stage qualitative design (Stage 1: expert interviews; Stage 2: biographical interviews with people with MS), existing governmental and organizational support measures for maintaining the work capacity of individuals with multiple sclerosis (MS) were analyzed, and proposals for improvement were developed. Additional state support measures were proposed, including relaxing the criteria for state assistance, creating a centralized contact point for MS-specific inquiries, and enhancing collaboration between [...] 279 741 |
Chemical Composition, Antioxidant Properties, and Nutritional Value of Diospyros kaki L. as a Potential Functional Foodby
Abstract
Persimmon (Diospyros kaki L.) is increasingly recognized as a nutrient-dense fruit rich in health-promoting compounds. This study aimed to comprehensively evaluate the nutritional composition, phenolic profile, antioxidant potential, and elemental content of D. kaki fruit and its contribution to dietary mineral intake. Proximate analysis revealed a high moisture content, low fat, and appreciable fiber and carbohydrate levels, supporting its classification as a low-calorie, fiber-rich food. Methanolic extracts exhib [...] 426 1202 |
Sexuality in Older Adults Receiving Palliative Care: A Fundamental Dimension through the End of LifeAbstract
The sexuality of older adults at advanced stages of illness, or at the end of life, remains a taboo topic that is rarely addressed in the literature and in practice. As a result, the knowledge base informing the support needs of older adults at the final stages of life with regards to sexuality remains scant. The present study seeks to explore experiences of sexuality in older adults with serious illness or receiving palliative care, focusing specifically on the place of sexuality in their lives, the forms of sexua [...] 391 1114 |
Characterization of Drought Severity Using GRACE and TerraClimate Dataset in the Rift Valley Basin, EthiopiaAbstract
Characterizing drought severity using GRACE and TerraClimate datasets is globally important because it enables consistent, large-scale monitoring of both surface and subsurface water availability across data-scarce regions. This integrated perspective supports improved drought assessment, climate change impact analysis, and informed water-resource management worldwide. The Ethiopian Rift Valley has experienced recurrent hydrological drought hazards, posing serious threats to water availability, agricultural product [...] 487 1471 |
Advancing Mathematical Learning in Children and Adolescents with Autism Spectrum Disorder through Serious Games and Educational Robotics: A Mini ReviewAbstract
Mathematical learning often presents persistent challenges for children and adolescents with Autism Spectrum Disorder (ASD) due to differences in Executive Functioning (EF), cognitive flexibility, and symbolic reasoning. These factors can hinder the development of numerical understanding and pre-mathematical reasoning, problem-solving, and abstract thinking, frequently resulting in disengagement and anxiety. In recent years, digital and embodied technologies—particularly Serious Games (SG) and Educational Robotics [...] 589 1730 |
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