Exposure to Mycotoxins: Neurological Disorders and Psychiatric Manifestations
Abstract
938 2399
Exposure to Mycotoxins: Neurological Disorders and Psychiatric ManifestationsAbstract
Mycotoxins, toxic secondary metabolites produced by fungi and molds, have negative health impacts on both humans and animals. They are commonly found in foods such as nuts, coffee, cereals, and grains, particularly in regions with warm, humid climates. Among the most prevalent mycotoxins in these foods are aflatoxin B1, ochratoxin A, zearalenone, patulin, and deoxynivalenol (DON). The presence of mold capable of producing mycotoxins within food contributes to an elevated risk of various illnesses, including those r [...] 938 2399 |
Impaired Cognitive Performance and Driving: A Comparative Study of Older Adults and Younger Adult Drug Usersby
Abstract
Driving is a complex cognitive behavior that is an essential part of everyday life and can be broken down into many subcomponents. Due to aging and medication interactions, a wide range of motor, sensory, and cognitive skills that are imperative for driving are affected in older adults. Several studies show that the number of crashes and mortality rates increase by age and the consumption of cannabis and cocaine is associated with a range of adverse mental and physical effects. The purpose of this study was to iden [...] 616 1333 |
Transformational Spaces: An Interpretative Phenomenological Inquiry into the Lived Experience of Young People Visiting Kanha Shanti Vanam Meditation Center, Telangana, Indiaby
Abstract
The innate desire to belong and to connect is profoundly human, yet in a world of instant communication, millions of young people increasingly feel untethered and adrift. Loneliness is the 21st century's primary health care concern across all age groups. Young people not only feel lonely and emotionally isolated, but they also describe a lack of meaningful connections and purpose. Young people lack safe spaces where they can connect with their peers, without fear of judgment, prejudice, and pressure to succeed. In [...] 356 1089 |
Analysis of Leukocyte Telomere Length in Brazilian People Living with HIV with and Without Cancerby
Abstract
Advances in antiretroviral therapy (ART) have normalized the life expectancy of people living with HIV (PLWH) but have been linked to a premature presentation of age-related comorbidities, including cancer. Telomere length (TL) is a marker of cellular aging and was investigated in blood leukocytes from 78 PLWH on ART, compared with 163 HIV-uninfected controls. The PLWH group was stratified into three subgroups: HIV-only (n = 57), HIV with AIDS-defining cancer (ADC, n = 9), and HIV with NADC (n = 12). Quantitative p [...] 447 1031 |
On the Prediction of Spur Gear Maintainability in Bottling Machines based on Failure Databy
Abstract
In bottling companies, spur gears play a vital role in ensuring efficient mechanical power transmission in bottling machines. Therefore, the maintainability of spur gears in these machines is important because it directly affects the overall efficiency, productivity, and cost-effectiveness of bottling operations. The study focused on data collection for different tasks performed on a failed gear from January to December of a particular year based on task time and frequency of occurrence, which are important factors [...] 348 964 |
Targeting Neuroinflammation in Difficult-to-Treat Depression: From Anti-Inflammatory Agents to Multi-Target Immunopsychiatric InterventionsAbstract
Difficult-to-treat depression (DTD) with inflammatory features (e.g., hs-CRP ≥3 mg/L and/or elevated IL-6) may represent a clinically and biologically distinct presentation characterized by chronicity, functional impairment, prominent cognitive-motivational symptoms, and suboptimal response to conventional treatments. Classical anti-inflammatory strategies (e.g., COX-2 inhibitors or cytokine-targeting biologics) have shown signals of efficacy in selected biomarker-enriched subgroups; however, overall evidence remai [...] 702 2071 |
Optimizing Psychopharmacotherapy Using Personality Biomarkers: A Seven-Factor Model PerspectiveAbstract
Personalized psychopharmacotherapy remains a critical yet underdeveloped frontier in psychiatry, as traditional approaches often fail to address substantial interindividual variability in drug efficacy and tolerability. While demographic, clinical, and genetic factors have improved treatment precision, they do not fully account for observed heterogeneity. Recent advances highlight the promise of personality traits, particularly as operationalized by Cloninger’s Seven-Factor Model, as novel biomarkers for treatment [...] 452 1221 |
Promising Electrocatalytic Systems 2,5-di-Me-Pyrazine-di-N-Oxide - Cyclohexanol - Single-Walled and Multi-Walled Carbon Nanotubes for the Simultaneous Metal-Free Oxidation of Cyclohexanol at Anode and Release of Hydrogen Evolution at Cathodeby
Abstract
Electrocatalytic oxidation of organic compound in the absence of noble metals or their oxides as catalysts and using metal-free electrodes is a "green" electrochemical, inexpensive and attractive process for practical use in electrocatalysis, power sources and sensors. The process accompanied by the elimination of protons, is of interest both for obtaining valuable organic compounds at the anode and for the release of hydrogen evolution at the cathode. In this work, the catalytic oxidation of cyclohexanol in the pr [...] 436 1122 |
Movement-informed Breathwork (MiB): Integrating Muscular Contractions with Slow Conscious Connected Breathing for Therapeutic ApplicationAbstract
This paper introduces Movement-informed Breathwork (MiB), a personalised breath-body approach with biofeedback that integrates a form of conscious connected breathwork (breathing without pauses) with targeted neuromuscular contraction and relaxation cycles. Drawing from neuromuscular torque chain dynamics, fascial research and sensorimotor trauma therapy principles, MiB aims to enhance autonomic regulation, interoceptive awareness and somatic-emotional integration by bridging traditional breathwork (deep, slow-pace [...] 498 2646 |
Balancing Preservation and Maximizing Utilization: A DCD Lung Procurement Strategy During Abdominal Normothermic Regional Perfusionby
Abstract
The increasing demand for organ transplantation has necessitated innovative strategies to maximize donor organ utilization, especially in donation after circulatory death (DCD) contexts. This article explores the integration of direct lung recovery with abdominal normothermic regional perfusion (A-NRP) to optimize organ preservation and expand the donor pool. A-NRP effectively mitigates warm ischemic injury, supporting the viability of both abdominal and thoracic organs. Our approach emphasizes meticulous surgical [...] 359 1345 |
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