by Ioannis Syros  , Anna Tsourdini  , Blossom Fernandes  and Xenia Anastassiou-Hadjicharalambous

Received: 23 September 2025;  Published: 22 January 2026;  doi: 10.21926/obm.neurobiol.2601319

Super Skills for Life (SSL) is a transdiagnostic psychoeducational program designed for children with anxiety and depressive symptoms based on cognitive-behavioral therapy. Empirically documented studies to date have demonstrated its immediate and long-term effectiveness in different contexts. The aim of this study was to assess the efficacy of the SSL program to reduce emotional and behavioral difficulties in a clinical sample of Greek-speaking primary school children aged 6 to 12. The program was implemented over [...]

by Chawannuch Ruaengsri  , Marc Leon  , Miguel Alvarez-Cortes  , Manuel Quiroz-Flores  and Yasuhiro Shudo

Received: 30 June 2025;  Published: 21 January 2026;  doi: 10.21926/obm.transplant.2601264

To address the pressing shortage of donor lungs, Donation after Circulatory Death (DCD) transplantation has become a vital strategy for expanding the donor pool. Minimizing warm ischemic injury is crucial for optimizing organ viability and function. This review synthesizes current evidence on Normothermic Regional Perfusion (NRP) and Ex-Vivo Lung Perfusion (EVLP) in DCD lung transplantation. Analysis reveals their growing efficacy in minimizing ischemic damage, facilitating organ assessment, and expanding the trans [...]

by Manal Hadi Ghaffoori Kanaan  , Beom-Jin Lee  , Sura Saad Abdullah  , Chulhun Park  , Abdolmajid Ghasemian  and Steward Mudenda

Received: 10 October 2025;  Published: 14 January 2026;  doi: 10.21926/obm.genet.2601325

Stem cell-derived exosomes (SDEs) have emerged as revolutionary mediators in cancer immunotherapy, offering unprecedented potential to reprogram the immunosuppressive tumor immune microenvironment (TIME). These nano-sized extracellular vesicles, laden with non-coding RNAs (ncRNAs), serve as natural biocompatible carriers, capable of orchestrating immune cell dynamics, stromal remodeling, and tumor cell fate. Unlike their tumor-derived counterparts, which often propagate oncogenic signals, SDEs uniquely harbor immun [...]

by Kamal A. R. Ismail  , Fatima A. M. Lino  , Mohamed Teggar  , Abdelghani Laouer  , Pedro L. O. Machado  , Felipe M. Biglia  and Thiago A. Alves

Received: 27 June 2025;  Published: 12 January 2026;  doi: 10.21926/aeer.2601002

Buildings account for a significant portion of global energy consumption, estimated at 30-40%, and also contribute to greenhouse gas emissions. Energy consumption in a building is mainly thermal (natural gas) and electrical. This energy is usually used for heating water, cooking, illumination, ventilation and air conditioning, powering appliances, floor heating, and other activities. These activities were examined, and their substitution by solar-based energy sources was reviewed. To achieve this objective, an exte [...]

by Irina G. Udina  , Marina A. Gubina  and Alesya S. Gracheva

Received: 04 June 2025;  Published: 12 January 2026;  doi: 10.21926/obm.genet.2601324

The purpose of the study was to consider the distribution of Y-chromosome DNA markers in samples from the populations of the three largest megalopolises (Moscow, Saint Petersburg, and Novosibirsk) in the Russian Federation, in the context of developing genetic databases. The study aimed to compare the frequency profiles of 18 Y-chromosome STRs (Short tandem repeats) and the level of genetic differentiation. Based on FST estimates for the distribution of these 18 Y-chromosome STRs, the senior generations of Moscow a [...]

by Orlando N. Guiñazú  , Edgar M. Sánchez Faba  , Griselda A. Eimer  , Laura E. Moyano  and Horacio Falcón

Received: 15 October 2025;  Published: 12 January 2026;  doi: 10.21926/cr.2601002

Pyrolysis is a promising technology for converting biomass waste into bio-oil, a liquid product that can serve as feedstock for fuels and high-value chemicals. In this study, bio-oil was produced via catalytic pyrolysis of pear pulp waste, a byproduct from juice and jam manufacturing, using a fixed-bed reactor. Initial non-catalytic experiments were conducted under nitrogen and vacuum atmospheres at temperatures ranging from 300 to 450°C for 15 minutes to evaluate the effect of temperature on bio-oil yield. The res [...]

by Paul Gilbert  , Derek Griner  , Kelly Morter  , Ptarmigan Plowright  , Jaskaran Basran  , Hannah Gilbert  , Victoria Nithsdale  , Eva Rogers  , Yoram Giglio  and Corinne Gale

Received: 07 April 2025;  Published: 12 January 2026;  doi: 10.21926/obm.icm.2601005

There is now good evidence for the efficacy of Compassion Focused Therapy (CFT) for a variety of mental health difficulties. To deepen understanding of the processes underpinning CFT’s effectiveness, this service evaluation explored the experiences and reflections of individuals with long-term mental health difficulties who had previously received therapy and attended an 11-week CFT group. Ten clients were invited to the group; one withdrew before the group started because of work and personal commitments and anoth [...]

by Uchechukwu Nwaiwu  , Fan He  , Matthew Leach  and Lirong Liu

Received: 31 July 2025;  Published: 12 January 2026;  doi: 10.21926/jept.2601002

Increasing local energy access in developing countries, particularly in off-grid regions where mini-grids are often overloaded, remains a critically underexplored area in energy transition. These regions often face significant technical and economic challenges, such as low generation capacity, high energy costs, limited energy access, and heavy reliance on diesel fuels. This study explores capacity expansion by integrating small-scale geothermal energy into such a mini-grid system to enhance the local energy supply [...]

by Rustam Nailevich Mustafin

Received: 29 September 2025;  Published: 08 January 2026;  doi: 10.21926/obm.genet.2601323

Tuberous sclerosis (TS) is one of the most common hereditary tumor syndromes, occurring with an average incidence of 1 in 9,000 newborns worldwide. The disease manifests itself through the development of tumors of the brain, kidneys, heart, lungs, and skin, along with characteristic depigmented spots. Tuberous sclerosis is caused by germline variants in the TSC1 (encoding hamartin) and TSC2 (encoding tuberin) genes. The hamartin-tuberin protein complex, together with the TBC1D7 molecule, inhibits the serine/threoni [...]

by Oteja Lightheart  and Helané Wahbeh

Received: 09 August 2025;  Published: 07 January 2026;  doi: 10.21926/obm.icm.2601004

Older adults in the U.S. have higher rates of depression, stress, and chronic diseases. There is an urgent need for effective interventions to reduce depressive symptoms and enhance overall health and well-being. Meditation presents an appealing therapeutic option due to its cost-effectiveness, minimal risks, ease of use, and active patient involvement, with growing evidence indicating its effectiveness in reducing depressive symptoms. Online platforms may provide more accessible options for meditation intervention [...]