Table of Content

Open Access Review

Mycobacterium Tubercular Mediated Inflammation and Lung Carcinogenesis: Connecting Links

Received: 03 September 2022;  Published: 21 June 2023;  doi: 10.21926/obm.genet.2302183

Abstract

Lung cancer is a leading cause of death among all the cancer worldwide and it has the highest occurrence and mortality rates. Mycobacterium tuberculosis (MTB) induced tuberculosis has been known as one of the risk factors for lung carcinogenesis. The exact mechanism of MTB is understood to date. Several research and epidemiological studies about the link between tuberculosis and lung cancer exist. It has been proposed that tuberculosis causes chronic inflammation, which increases the risk of lung cancer by creating [...]

1184 8164

Open Access Original Research

Effects of Waste Cooking Oil Biodiesel on Performance, Combustion and Emission Characteristics of a Compression Ignition Engine

Received: 07 February 2023;  Published: 20 June 2023;  doi: 10.21926/jept.2302020

Abstract

With their higher sustainability index, biofuels, environmentally-friendly and renewable nature is a viable alternative energy source in the transportation sector. This study presents the effect of waste cooking oil (WCO) biodiesel on performance, combustion, and emission from a compression ignition engine. The biodiesel was blended with diesel in varying proportions of 5% biodiesel and 95% diesel (designated as B5), 10% biodiesel in diesel (B10), 15% biodiesel in diesel (B15), 20% biodiesel in diesel (B20), 50% bi [...]

1401 12738

Open Access Concept Paper

Wave Age and Steepness Relation in Growing Wind Seas: A Case Study during Hurricane Matthew in 2016

Received: 12 March 2023;  Published: 20 June 2023;  doi: 10.21926/aeer.2302037

Abstract

For wind-wave interaction studies, from the literature, two criteria for the wind sea are used: one is the wave age and the other wave steepness. Analysis of pertinent datasets from a data buoy near the passage of Hurricane Matthew in 2016 indicates that CpU10 = -15 HsLp + 1.3. Here CpU10 is the wave age and HsLp is the wave steepness, where Cp is the phase speed of the peak wave, U10 is the wind speed at 10 m, Hs is the significant wave height, and Lp is the peak or dominant wave length. It is found that 87% of th [...]

1069 7361

Open Access Original Research

Micromechanics-Based Modeling of SiC/SiC Ceramic Matrix Composites and Structures

Received: 23 January 2023;  Published: 20 June 2023;  doi: 10.21926/rpm.2302025

Abstract

The behavior and response of ceramic matrix composites (CMCs), in particular silicon carbide fiber reinforced silicon carbide matrix (SiC/SiC), is affected by many factors such as variation of fiber volume fraction, residual stresses resulting from processing of the composites at high temperature, random microstructures, and the presence of matrix flaws (e.g., voids, pores, cracks etc.) as well as general material nonlinearity and heterogeneity that occurs randomly in a composite. Residual stresses arising from the [...]

1805 12344

Open Access Original Research

Kidney Transplantation in Nigeria: A Single Centre’s Early Surgical Experience and Outcomes

Received: 19 March 2023;  Published: 19 June 2023;  doi: 10.21926/obm.transplant.2302189

Abstract

With the rise in the population of patients with End-stage Renal Disease (ESRD) in Nigeria, there is an increased demand for Renal Replacement Therapy (RRT) including kidney transplantation (KT). We present our initial surgical experience and early outcomes with KT at a Nigerian transplant center over 2 years. A 2-year retrospective review of patients who underwent KT was done. Data of both kidney donors and recipients were recorded in designed proformas. Extracted information included demographic characteristics, [...]

2474 21577

Open Access Original Research

Efficacy of Zinc Pyrithione as A Novel Anti-Bacterial Coating Agent

Received: 02 May 2022;  Published: 15 June 2023;  doi: 10.21926/rpm.2302024

Abstract

Zinc pyrithione (ZPT) is used to prevent microbial degradation and deterioration of manufacturing starting materials such as plastics, polymers, and latexes. The main objective of this study was to evaluate the anti-bacterial properties of ZPT. Currently, there is insufficient data on the effect of ZPT on viability of commonly encountered bacterial pathogens. We tested the efficacy of ZPT manufactured in the form of film rolls as an anti-bacterial protective layer by using the ASTM–recommended protocol on gro [...]

1929 13833

Open Access Short Communication

Surgical Tips for Improving Success Rate of Deep Anterior Lamellar Keratoplasty in Keratoconus

Received: 20 April 2023;  Published: 15 June 2023;  doi: 10.21926/obm.transplant.2302188

Abstract

This article aims to provide some personal surgical tips to increase the success rate of deep anterior lamellar keratoplasty (DALK), a very advantageous yet complex procedure for treating keratoconus. The most troublesome surgical step is obtaining a successful pneumatic dissection of the deep stromal tissue, allowing the exposure of a deep cleavage plane. The following tips may aid the trainee surgeon in mastering this step, among others: performing a deep trephination, using intraoperative anterior segment optica [...]

998 7197

Open Access Review

Spinal Muscular Atrophy: An Overview

Received: 10 April 2023;  Published: 14 June 2023;  doi: 10.21926/obm.genet.2302182

Abstract

Spinal muscular atrophy, a leading cause of infant death, is a neurodegenerative disease classified categorically based on age of onset and achieved motor function. The standard method of diagnosis is through molecular genetic testing, ideally through the newborn screen to facilitate early diagnosis and treatment. There are 4 types of spinal muscular atrophy, each with varying degrees of symptoms based on the number of survival motor neurons. Current treatment options include gene therapy and supportive care. Futur [...]

1384 10662

Open Access Original Research

Successful Online Choir for People Living with Dementia: A Qualitative Case Study

Received: 26 February 2023;  Published: 13 June 2023;  doi: 10.21926/obm.icm.2302024

Abstract

Group singing as a social musical activity can be used to improve the quality of life, well-being, and overall health of people with dementia and caregivers. Online choirs have gained awareness since the COVID-19 pandemic; however, singing in an online choir is an unsatisfying experience for most choir members in the general population. In order to report on the feasibility of creating an online choir for people with dementia, we studied a successful case of such a choir. This choir began and continued online for o [...]

1444 9266

Open Access Original Research

The Geriatric Impact in the Management of Complex Cancer Patients: A Monocenter Experience

Received: 17 November 2022;  Published: 13 June 2023;  doi: 10.21926/obm.geriatr.2302238

Abstract

New technologies, aging-related changes, and evolution in patients' needs have led to a new scenario in all oncological fields in front of which we have to move on. Technological progress has made it possible to increase the number of patients treated, including elderly patients and generally those at higher risk of toxicity. However, this scenario has led to new problems requiring new skills to be addressed. For this reason, Gemelli-ART (Advanced Radiation Therapy) of Fondazione Policlinico Universitario A. Gemell [...]

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