Neurobiology of Sleep and Microbiomics in Aging
Abstract
2098 15531
Neurobiology of Sleep and Microbiomics in Agingby
Abstract
(1) Background: The daily rhythms of life on earth are governed by a central clock located in the hypothalamus and entrained primarily by light. By virtue of its connections to a myriad of other clocks located both in the brain and in peripheral organs and cells, this clock provides a timing signal based on the light/dark cycle by which organismal physiology and behaviour are governed. Disturbances of these natural rhythms have multiple downstream effects, frequently resulting in dysregulations of sleep and wake cy [...] 2098 15531 |
FASD and Brain Development: Perspectives on Where We are and Where We Need to Goby
Abstract
Maternal consumption of alcohol (ethanol) during pregnancy can lead to life-long neurobehavioral and cognitive abnormalities in the offspring, collectively referred to as Fetal Alcohol Spectrum Disorders (FASD). Prenatal exposure to ethanol is one of the leading causes of non-genetic intellectual disability and FASD is an umbrella category that includes Fetal Alcohol Syndrome, Partial Fetal Alcohol Syndrome, Alcohol Related Birth Defects, and Alcohol Related Neurodevelopmental Disorder. Children with a history of&n [...] 2143 13311 |
Perspectives on the Neurobiology of Antipsychotic Drugs in Psychiatric DisordersAbstract
Antipsychotics have been a pillar in the treatment of schizophrenia since their introduction more than 60 years ago. Their variety in structures and receptor binding properties confers on them a complex clinical profile of effectiveness and risk of adverse side-effects. Although antipsychotics are best known for their therapeutic effects in schizophrenia, these are limited to the positive symptoms, with much less influence on negative symptoms or cognitive deficits. Moreover, although the newer (so-called second-ge [...] 1999 15504 |
Scenario-Based Assessment of Life-Cycle GHG Emissions from Grid-Connected Photovoltaic Systems under Different Electricity Mixesby
Abstract
This study evaluates the carbon-related performance of grid-connected photovoltaic (PV) systems under different electricity-generation mixes using a literature-based, scenario-oriented life-cycle GHG emissions assessment. A 1 MWp utility-scale crystalline-silicon PV reference system was defined with an annual electricity generation of 1,640 MWh, a 30-year lifetime, and an annual degradation rate of 0.5%, resulting in a projected cumulative electricity output of 45,793.99 MWh. The analysis considered three benchmark [...] 183 512 |
Formation Testing Permeability and Pore Pressure Prediction in Open Hole and Isolated Straddle Packer ApplicationsAbstract
Knowledge of permeability, which measures a rock formation’s resistance to fluid flow, is essential to energy exploration, oilfield development and economic viability, since its value directly relates to cash flow and outlay: the greater permeability is, the faster monetary gains are realized, the lower the initial investment required. Formation testing is crucial to this understanding. It assists with reservoir characterization as it enables direct fluid sampling, reducing the need for resistivity, acoustic and nu [...] 142 483 |
Real-Time Prediction of Anisotropies kh and kv in Dual Axial Probe Formation TestingAbstract
Understanding anisotropy in reservoir dynamics is essential to energy exploration, oilfield development and economic viability since this indicator describes the natural flow directions preferred by the underground fluid. Quantifying its effects allows oil companies to design drilling programs and production facilities that extract the greatest benefit from newly discovered resources. Formation testers are important because they provide direct clues on hydrocarbon properties and resistance to flow through fluid sam [...] 143 442 |
Battery-Less Off-Grid Renewable Microgrid: A Review of Storage Alternatives and PV-WT-CSP Integration with Green HydrogenAbstract
Renewable energy systems play a critical role in reducing carbon emissions and promoting energy sustainability. Conventional battery storage remains the dominant but problematic solution for intermittency management in off-grid renewable energy systems (RES), imposing high capital costs ($150-400/kWh for lithium-ion), short replacement cycles of 3-15 years, and significant environmental burdens from toxic material disposal barriers that are particularly acute in the remote and resource-limited communities that most [...] 489 1751 |
Ethanol-Based Organosolv Pretreatment for Enhancing Enzymatic Hydrolysis of Corn Straw, Corn Cob, Sugarcane Straw, and Sugarcane Bagasseby
Abstract
Organosolv pretreatment is an attractive approach to disrupt the recalcitrant structure of lignocellulosic biomass from agroindustrial wastes, aiming to facilitate its bioconversion into valuable bioproducts. This study investigated the ability of an ethanol/water (1:1 v/v) organosolv pretreatment to improve the enzymatic digestibility of sugarcane bagasse (SB), sugarcane straw (SS), corn straw (CS), and corn cob (CC) for the production of reducing sugars and monosaccharides, aiming at future applications in bioeth [...] 532 1151 |
Correction: Zhang D. Operation of AC Microgrids with PV Panels’ Output Power Curtailment for Minimizing the Use of Energy Storage. Journal of Energy and Power Technology 2022; 4: 008by
Abstract
In this paper, a method for operating AC microgrids in both off-grid or standalone and grid-connected modes is proposed to minimize the use of energy storage by increasing the number of PV panels and curtailing their output power. When the intensity of daylight decreases, power is imported from the main grid through an AC/DC/AC converter or solid-state transformers in parallel to compensate for the shortage. By using a three-phase transformer in Δ-Y connection with Y’s neutral connected to its local grounding syste [...] 329 765 |
Technical and Economic Feasibility Assessment of a Mini Wind Turbine Using Statistical Method for Sustainable Urban Energy: A Case Study of Zvishavane Urban, ZimbabweAbstract
Unreliable electricity supply remains a significant barrier to economic development in sub-Saharan Africa, with Zimbabwe experiencing acute load-shedding that disrupts residential, commercial, and industrial activity. This paper presents a techno-economic feasibility assessment of a mini wind turbine for distributed urban energy generation in Zvishavane, Zimbabwe. Wind resource data were sourced from two independent platforms Weather Spark (30-year climatological record) and Meteoblue (high-resolution reanalysis) a [...] 1097 2711 |
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