by Eugene Stephane Mananga  and Lamisa Rusmeha

Received: 23 December 2020;  Published: 13 April 2021;  doi: 10.21926/obm.icm.2102012

Towards the end of 2019, an unanticipated outbreak, coronavirus also referred to as COVID-19’s first cases occurred in Wuhan City, Hubei Province, China. In early 2020, the World Health Organization (WHO) declared the pandemic as a Public Health emergency of international concern. COVID-19 is a transmissible disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The COVID-19 puts a spotlight on numerous issues varying from educational, social, political, and economic that were already prese [...]

by Sara B Taylor  , Kristy Arbon  and Faith Reynolds

Received: 27 October 2020;  Published: 31 March 2021;  doi: 10.21926/obm.icm.2101011

Somatic Self-Compassion® training is a newly developed trauma-informed self-compassion training that was designed to combine interoception and sensory modulation in order to teach individuals to more effectively cope with current and past stress. Thirty-two non-clinical adults across five cohorts participated in this pre-post design feasibility study. Participation in Somatic Self-Compassion® Online resulted in significant reductions in perceived stress, internalized shame, and bodily shame and significant improvem [...]

by Keita Kiuchi  , Katsumasa Kishi  and Kanto Araki

Received: 23 December 2020;  Published: 17 March 2021;  doi: 10.21926/obm.icm.2101010

This study investigated the physical and psychological impacts of elements related to coronavirus disease (COVID-19) and demographic data in Japan both directly and as mediated by stressors, immediately following the rescinding of the state of emergency declaration accompanying the severe acute respiratory syndrome coronavirus 2 outbreak. An online survey was administered to 1,500 Japanese registered with an online outsourcing service. Data were analyzed with structural equation modeling using Mplus. Relatively lar [...]

by Gerhard Litscher  , Tong Li  and Fengxia Liang

Received: 14 March 2021;  Published: 15 March 2021;  doi: 10.21926/obm.icm.2101009

In a pioneer transcontinental pilot study conducted with 50 volunteers, it was revealed that women could have apparently overcome the world's toughest lockdown in terms of changes in the general state of health measured using the heart rate variability parameter better than men. The results of the present study obtained in Wuhan provide information on the initial trend in this regard.

by Kanto Araki  , Keita Kiuchi  and Katsumasa Kishi

Received: 28 December 2020;  Published: 12 March 2021;  doi: 10.21926/obm.icm.2101008

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) outbreak is expected to have harmed the mental health of numerous people worldwide. Therefore, the present study was aimed to explore the effects of the SARS-CoV-2 outbreak on the overall health of the general Japanese population, with a particular focus on identifying the factors associated with a requirement for mental health treatment. Japanese residents aged 18 years and above were surveyed online, and among the 1,500 obtained responses included for a [...]

by Lucille Marchand  , Donna Lewin  and Leila Kozak

Received: 02 October 2020;  Published: 22 February 2021;  doi: 10.21926/obm.icm.2101007

Both palliative care (PC) and integrative medicine (IM) focus on the whole person to optimize wellbeing. Integrative palliative care combines the best of both approaches in relieving the distressing symptoms of serious illness and its treatment by combining evidence informed, pharmacological and nonpharmacological modalities that are aligned with the person’s goals, values and preferences. Healing is valued, as well as symptom relief, shared decisionmaking, person empowerment, compassionate care, and nurturing of h [...]

by Mitsuro Chiba  , Masafumi Komatsu  , Satomi Watanabe  and Yoko Daimon

Received: 13 January 2021;  Published: 20 February 2021;  doi: 10.21926/obm.icm.2101006

The high prevalence of obesity is a global concern. However, obesity and inflammatory bowel disease have similarities in epidemiology, diet, and gut microbial dysbiosis. An omnivorous (westernized) diet replacement with a plant-based diet in inflammatory bowel disease achieved better outcomes in both the induction and quiescent phases. Educational hospitalization providing a plant-based diet was found effective in suppressing flare-up in ulcerative colitis. This case report was designed to assess whether a plant-ba [...]

by Allison Ast  , Margaret Meyer  , R. Elyse Heidelberg  , Jennifer M. Allen  , Amy Ly  and Holly Spraker-Perlman

Received: 02 December 2020;  Published: 08 February 2021;  doi: 10.21926/obm.icm.2101005

Children with cancer can experience intense suffering. Currently, despite our best efforts, symptoms associated with both cancer and its treatment result in physical, psychological, and emotional discomfort that can be difficult to manage with traditional Western medicine alone. Developing integrative services within a pediatric hematology-oncology program may help improve cancer-related symptoms by combining different modalities targeting overall health with traditional oncology care. This study details the initia [...]

by Sharon F. Clevenger

Received: 20 December 2020;  Published: 07 February 2021;  doi: 10.21926/obm.icm.2101004

Healthcare workers (HCWs) have been adapting to the changing needs of people worldwide in response to the COVID-19 pandemic. The purpose of this descriptive study was to evaluate how HCWs are managing dietary self-care needs during the increased stress-load of the COVID-19 pandemic and determine if nutritional changes are being made that could place them at higher risk for mental health problems. A cross-sectional epidemiological nonprobability snowball sampling design was used to expand access to participants. Occ [...]

by Gerhard Litscher

Received: 18 January 2021;  Published: 20 January 2021;  doi: 10.21926/obm.icm.2101003

Neuro-photobiomodulation (PBM) is a relatively novel optical stimulation method that is not yet generally accepted in conventional medicine. Therefore, evidence-based research in this sub-area, which is important for laser medicine, is necessary in order to provide appropriate scientific evidence for a better understanding of neuro-PBM. In this editorial, a summary of the recent results with stimulation using different frequencies (e.g., 40 Hz, 136.1 Hz) is presented. The contribution is intended to stimulate resea [...]

by Arnaud Philippot  , Yannick Bleyenheuft  and Anne De Volder

Received: 21 June 2020;  Published: 07 January 2021;  doi: 10.21926/obm.icm.2101002

In a previous study conducted to assess the impact of physical exercise on the symptoms of depression and anxiety in preadolescents in the school environment, which included a subgroup of participants comprising eleven randomly selected teens (aged 9–11) and all enrolled in primary education, it was immediately observed that one participant referred to as Andy was being bullied and teased, and the teachers were completely unaware of this scenario. All the participants of the study were volunteers, and were subjecte [...]

by OBM Integrative and Complementary Med Editorial Office

Received: 07 January 2021;  Published: 07 January 2021;  doi: 10.21926/obm.icm.2101001

The editors of OBM Integrative and Complementary Medicine would like to express their sincere gratitude to the following reviewers for assessing manuscripts in 2020. We greatly appreciate the contribution of expert reviewers, which is crucial to the journal's editorial process. We aim to recognize reviewer contributions through several mechanisms, of which the annual publication of reviewer names is one. Reviewers receive a voucher entitling them to a discount on their next LIDSEN publication and can download a [...]

by Takahiro Fujimoto  , Hidetake Kobayashi  , Takeshi Hataoka  , Kazuo Taniguchi  and Keisuke Miura

Received: 17 May 2020;  Published: 09 December 2020;  doi: 10.21926/obm.icm.2004045

Obesity causes serious long-term health problems in people worldwide. Since the effect of dietary advice is possibly limited, weight loss can be a major challenge; therefore, additional weight control techniques may be beneficial. We conducted four experiments to evaluate if auricular acupuncture point stimulation with simple metal beads (AA) rather than the popular use of intradermal needle (DA) to stimulate auricle would support weight loss. In this retrospective study, weight change in Japanese women (aged 18 to [...]

by Wangkuk Son  , Jason Lin  and Melissa Puppa

Received: 28 September 2020;  Published: 07 December 2020;  doi: 10.21926/obm.icm.2004044

Cancer cachexia contributes to 30% of cancer-related deaths. There is currently no treatment or standard of care for cancer cachexia. Many nutritional interventions show promise for the treatment and or prevention of cachexia. Supplementation with omega-3 fatty acids, protein and vitamins either alone or in combination has shown some beneficial effects in the prevention and treatment of cancer cachexia. The mechanisms through which many nutritional interventions work to attenuate cachexia are just beginning to be u [...]

by Gerhard Litscher

Received: 11 November 2020;  Published: 13 November 2020;  doi: 10.21926/obm.icm.2004043

The Nogier reflex or reflex auriculo-cardiac (RAC) or the dynamic pulse reaction is a physiological phenomenon that is not generally accepted in conventional medicine. Therefore, evidence-based research in this sub-area is important for auricular medicine as it provides appropriate scientific evidence for better acceptance. In this editorial, a RAC measurement based on a modified smartphone registration and analysis is presented. The contribution is intended to stimulate researchers to continue working in this inte [...]

by Vasilios M. Polymeropoulos

Received: 01 August 2020;  Published: 26 October 2020;  doi: 10.21926/obm.icm.2004042

There is a dramatic need for extensive research into the predictors of severe infection with SARS-CoV2 and therapeutic options for infected people. People who suffer from severe illness and higher mortality display a pattern of having specific co-morbidities (diabetes, obesity, hypertension) and are of higher age. Recent research has described methods of viral entry via receptors (ACE2, TMPRSS2) and the hyper-inflammatory state often associated with severe illness (increase in interleukins, increase in TNF-alpha). [...]

by Emily Reeves  , Brigitte Liebig  and Eveline Degen

Received: 14 July 2020;  Published: 20 October 2020;  doi: 10.21926/obm.icm.2004041

High-quality care is an important aim of palliative care services. However, the quality of care is a complex phenomenon and is subjectively perceived by those who are closest to the services and are often evaluated poorly. Prior research has highlighted the difficulties in evaluating the quality of care because of different perspectives, and still, only a little is understood about the perception of the quality of care in palliative care services. Investigating the perspectives of key individuals involved in pallia [...]

by Deborah R. Simkin  and L. Eugene Arnold

Received: 06 April 2020;  Published: 19 October 2020;  doi: 10.21926/obm.icm.2004040

Teen depression and suicide rates have risen despite conventional treatments. This article reviews adjunctive interventions that may improve outcomes. A search of the National Library of Medicine database used tailored searches with combinations of specific terms. Modern lifestyle is associated with increased inflammation and pro-inflammatory cytokines leading to, for instance, hyperactivation of the hypothalamic-pituitary-adrenal axis, which promotes depression. Inflammation also increases oxidative stress, leadin [...]

by Giuseppe De Benedittis

Received: 25 August 2020;  Published: 31 August 2020;  doi: 10.21926/obm.icm.2003039

by Mario F. Tecce  , Walter Milano  and Anna Capasso

Received: 26 June 2020;  Published: 31 August 2020;  doi: 10.21926/obm.icm.2003038

Adipocytes play a central role in maintaining lipid homeostasis and energy balance by storing triacylglycerols (TAGs) or releasing free fatty acids in response to changes in energy requirements. Obesity is a major risk factor for many diseases, including diabetes, hypertension, and cardiovascular disease. Besides, morbidity and mortality associated with being overweight and obese are on the rise. The development of obesity is characterized by an increase in lipid cells due to mitogenesis and differentiation, which [...]

by Melissa Gaule  , Erin Allen  and Kathleen Benton

Received: 29 March 2020;  Published: 26 August 2020;  doi: 10.21926/obm.icm.2003037

by Ramesh Alluri  , Hardik Ghelani  , Shayal Devi  , Vamsi Krishna Inampudi  and Srinivas Nammi

Received: 03 May 2020;  Published: 07 August 2020;  doi: 10.21926/obm.icm.2003036

To investigate the blood glucose lowering effect of the seed powder of T. foenum-graecum Linn (Papilionaceae) in normal and alloxan-induced diabetic rabbits. The blood glucose lowering effect of the seed powder was determined in normal and alloxan-induced (100 mg/kg, i.v.) diabetic rabbits, after oral administration of doses of 50, 100 and 150 mg/kg body weight. Blood samples were collected from the marginal ear vein before and also at 4, 6, 8, 10, 12, 16, 18, 20 and 24 h after drug administration and blood glucose [...]

by Francisco V. Muñoz  and Linda Larkey

Received: 20 May 2020;  Published: 27 July 2020;  doi: 10.21926/obm.icm.2003035

Breast cancer survivors (BCSs) report decrements in cognitive functioning. A Meditative Movement (MM) program (Qigong/Tai Chi Easy) combines meditation and exercise, practices known to improve cognitive function. Method: Using a single group, pre- to post-intervention assessment design, a pilot study was conducted in BCSs to test the effects of an 8-week MM intervention on cognitive functioning, sleep and mood and to explore changes on selected gene expression factors, BDNF, NF-kB1, and TP53, expected to improve wi [...]

by Kokila Jeyamurugan  and Ratna B Basak

Received: 12 May 2020;  Published: 17 July 2020;  doi: 10.21926/obm.icm.2003034

Child life specialists (CLS) are trained providers who form part of a pediatric multidisciplinary and pediatric palliative care team. Their role is invaluable to mitigate the stress and anxiety of children during hospitalization. They may use various strategies in children like play, art and music therapy and pet therapy, to help self-express and cope with painful procedures. We present a brief narrative on CLS with a case of a 10- year- old Hispanic boy who had metastatic osteosarcoma. The case illustration is f [...]

by Maya Kudo  , Misa Hayashi  , Peng Tian  , Danyang Liu  , Lili Wu  , Wei Li  , Zhaoyang Hong  , Yitang Zhao  , Toshiaki Nishigaki  , Masaaki Nishihara  , Kazuo Koike  , Tonghua Liu  and Ming Gao

Received: 13 April 2020;  Published: 09 July 2020;  doi: 10.21926/obm.icm.2003033

Increased body fat mass can lead to lifestyle diseases such as hypertension, diabetes, and hyperlipidemia. Metabolic syndrome is a cluster of conditions that increases the onset of multiple diseases, such as cardiovascular diseases, stroke, and type 2 diabetes, which are closely related to lipid metabolism; therefore, new prevention approaches and treatments are needed. Our study investigated the effects and mechanism of YNCRG on anti-obesity in metabolic syndrome model SHR.Cg-Leprcp/NDmcr (SHRCP) rats. Eight-week- [...]

by Enrico Facco

Received: 04 February 2020;  Published: 08 July 2020;  doi: 10.21926/obm.icm.2003032

The topic of resilience is of paramount importance. Although the term resilience was coined in the fields of physics and engineering, its use has spread to the fields of social sciences, biology, psychology, and psychiatry, as well as to the industry. Moreover, the term is now endowed with a wide range of meanings. The topic of resilience plays a central role in all critical life events. It is of paramount importance in medicine as well as in psychology and psychotherapy, where it is involved in both psychiatric di [...]

by Sharon Clevenger

Received: 02 April 2020;  Published: 18 May 2020;  doi: 10.21926/obm.icm.2002031

The novel coronavirus COVID-19 is a viral pathogen that first emerged in Wuhan, China in 2002 and has spread to 202 countries (as of March 28, 2020) [1]. Despite the fact that the 2005 SARS-CoV pandemic infected over 8,500 people, and caused over 800 deaths with billions of dollars in economic loss worldwide, as of 2015 there were still no clinically approved antiviral drugs, vaccines or monoclonal antibody therapies to treat SARS-CoV infections [2]. Antiviral medications that have been used to treat or control oth [...]

by Gerhard Litscher

Received: 15 April 2020;  Published: 11 May 2020;  doi: 10.21926/obm.icm.2002030

In this technical report, we present for the first time a newly developed multimodal light-emitting diode (LED) pad for photobiomodulation (PBM). In order to demonstrate the range of possibilities for its application, we carried out a comparison of measurements with and without infrared (IR) LEDs in a volunteer, and are presenting the results. The pad consists of several components, which are mainly composed of LEDs of different modalities (IR, red, yellow, and blue). This multicolor system was applied to a periphe [...]

by Joseph P. Green  , Steven Jay Lynn  , Olivia J. Green  , Victoria R. Bradford  and Rouhangiz Rasekhy

Received: 18 February 2020;  Published: 11 May 2020;  doi: 10.21926/obm.icm.2002029

Since Charcot [1], researchers and theorists have associated hypnotic responsiveness with dissociation. However, contemporary researchers have typically not documented impressive or statistically significant correlations between the most commonly used measure of dissociation, the Dissociative Experiences Scale-II [2, 3] and hypnotic responsiveness. We examined the ability of two measures of non-pathological dissociation, which have received scant attention in the hypnosis literature, the Wessex Dissociation Scale ( [...]

by Audrey Vanhaudenhuyse  , Anne-Sophie Nyssen  and Marie-Elisabeth Faymonville

Received: 14 February 2020;  Published: 09 May 2020;  doi: 10.21926/obm.icm.2002028

Hypnosis is a modified state of consciousness widely used to decrease pain perception in research protocols and clinical practice. In recent decades, hypnosis has been increasingly proposed to patients to re-engage their resources and capacities to modulate pain and emotional distress and to improve their treatment and recovery of well-being. Neuroimaging research helps clinicians to understand better how hypnosis works in terms of brain modulation. Hypnotic suggestions dramatically influence the self and environme [...]

by Lucy Watts  , Joanna Smith  , Wilfred McSherry  , Michael Tatterton  and Alison Rodriguez

Received: 08 May 2020;  Published: 08 May 2020;  doi: 10.21926/obm.icm.2002027

by Gerhard Litscher

Received: 03 May 2020;  Published: 07 May 2020;  doi: 10.21926/obm.icm.2002026

The present moment lacks any reliable vaccine or treatment for the SARS-CoV-2 virus and the resultant disease COVID-19 (Corona Virus Disease-2019). Laser medicine like photobiomodulation (PBM) or photodynamic therapy (PDT), and laser acupuncture may possess some potential to interact and relieve the symptoms of this disease. PubMed lists only two results for the search term ‘PBM or PDT and COVID-19’, indicating the paucity of validated scientific clinical studies on the subject. On the contrary, it does not mean th [...]

by Barbara Schmidt  , Teresa Deffner  and Jenny Rosendahl

Received: 11 December 2019;  Published: 28 April 2020;  doi: 10.21926/obm.icm.2002025

Patients in the intensive care unit are confronted with an extreme situation that may cause stress and anxiety. The negative experiences may cause patients to suffer for the long-term after leaving the intensive care unit. One such stressor in the intensive care unit is non-invasive ventilation. Positive therapeutic suggestions under hypnosis can help patients in intensive care to enhance their well-being by helping them to deal with specific stress like being ventilated. The aim of our study is to assess the effec [...]

by Heidrun Männle  , Birthe Osorio  and Karsten Münstedt

Received: 09 March 2020;  Published: 28 April 2020;  doi: 10.21926/obm.icm.2002024

Palliative care is a steadily growing component of medicine that focuses on treating individuals with life-limiting diseases such as cancer. It aims at improving the quality of life and alleviating cancer-related symptoms, including anxiety, pain, dyspnea, cough, nausea/vomiting, and constipation, which could result in significant physical and mental impairment. Integrative palliative care (IPC), as a subspecialty of palliative care, includes complementary approaches to treat patients holistically in their biopsych [...]

by Giuseppe De Benedittis

Received: 18 February 2020;  Published: 24 April 2020;  doi: 10.21926/obm.icm.2002023

There is increasing evidence demonstrating that hypnosis could be effective in the down-modulation of pain sensation in both acute and chronic pain states. In the neurophysiological context, recent evidence has deciphered, to a certain extent, the mystery of pain relief upon hypnosis. It is probable that hypnotic suggestions of analgesia are able to modulate pain processing at multiple levels and sites within the central nervous system (CNS). At the peripheral level, hypnosis may modulate the nociceptive input thro [...]

by Valérie Morin-Alain  , Eddy Larouche  , Anne-Marie Chouinard  , Marie-Claude Audet  , Sonia Goulet  , Louis-Simon Rousseau  and Carol Hudon

Received: 23 November 2019;  Published: 17 April 2020;  doi: 10.21926/obm.icm.2002022

Peripheral inflammation plays an important role in the pathophysiology of Alzheimer’s disease (AD) and dysregulations in circulating levels of different inflammatory mediators are detectable as early as the mild cognitive impairment (MCI) stage towards AD. Depressive symptoms, another risk factor of AD, are often found in individuals with MCI and associated with heightened levels of peripheral inflammatory mediators. Diminution in depressive symptoms and alterations of peripheral inflammation profiles have been obs [...]

by Paulo Henrique Fernandes de Oliveira  and Reginaldo de Carvalho Silva Filho

Received: 29 December 2019;  Published: 15 April 2020;  doi: 10.21926/obm.icm.2002021

Rosacea is a chronic inflammatory disease of the skin characterized by facial papules, pustules, erythema, and telangiectasia. Emotional factors such as stress and anxiety may induce and aggravate the symptoms of rosacea. It is hypothesized that tongue acupuncture, a technique that has been used successfully in the treatment of various neurological and psychiatric diseases, could be beneficial in relieving rosacea symptoms. This study evaluated the immediate effect of tongue acupuncture at specific anatomical point [...]

by Lisa Vogelgesang  , Damien Moore  and Paul D. Loprinzi

Received: 12 April 2020;  Published: 15 April 2020;  doi: 10.21926/obm.icm.2002020

by Ronald J. Pekala  and Kevin Creegan

Received: 20 January 2020;  Published: 13 April 2020;  doi: 10.21926/obm.icm.2002019

Noetic analysis is a methodology to quantify the mind during hypnosis, meditation, or other stimulus conditions/states of consciousness in a reliable and valid manner. The methodology uses retrospective phenomenological assessment (RPA) to comprehensively assess subjective experience. By having the participant complete a first person, self-report questionnaire, the Phenomenology of Consciousness Inventory (PCI), in reference to a short stimulus condition, the researcher can generate a “snapshot” of the mind, and it [...]

by Fernando Cabo  and Isaac Aguaristi

Received: 01 April 2020;  Published: 02 April 2020;  doi: 10.21926/obm.icm.2002018

by Krisztian Kasos  , Luca Csirmaz  , Fanni Vikor  , Szabolcs Zimonyi  , Katalin Varga  and Anna Szekely

Received: 07 February 2020;  Published: 01 April 2020;  doi: 10.21926/obm.icm.2002017

Hypnosis has proven to be an effective treatment in disorders that affect the autonomic nervous system (ANS). However, the studies investigating the nature of its effect on the ANS have reported contradictory results. Measurement of electrodermal activity (EDA) is an objective way to assess the activity of the sympathetic branch of the ANS. We aim to elucidate the effects of hypnosis on EDA. Here, we report the results of two studies, both investigating the psychophysiological effects of hypnosis.In the first exper [...]

by Cynthia M.A. Geppert  and Ronald W. Pies

Received: 17 March 2020;  Published: 23 March 2020;  doi: 10.21926/obm.icm.2001016

Cultural and religious competence is an essential component of palliative and end-of-life care. Because religious, ethnic and racial groups often differ in their values and preferences, including their attitudes toward palliative and end-of-life care, clinicians must maintain an open and respectful attitude toward these differences. Cultural and religious competence can improve palliative and end-of-life care, and strengthen the therapeutic alliance with patients and their families.

by Yan Yang  , Gerhard Litscher  , Zemin Sheng  and Lu Wang

Received: 12 February 2020;  Published: 20 March 2020;  doi: 10.21926/obm.icm.2001015

Pain could be directly related to autonomous imbalance. To date, only one scientific work examining heart rate variability (HRV) and heart rate (HR) as the important parameters of autonomous nervous system (ANS) in the context of clinical routine acupuncture treatments for lumbosacral pain conditions is available in the listed databases. The present study aimed to investigate the short-term effects of HRV and HR, during and after the acupuncture needle stimulation in patients with lower back pain. Eighteen patients [...]

by Antonella Ciaramella

Received: 01 January 2020;  Published: 17 March 2020;  doi: 10.21926/obm.icm.2001014

Over the last 30 years, several neuroimaging and neurophysiological experiments have lent support to the neuropsychology of consciousness, and several definitions have followed to describe it. The phenomenological perspective of consciousness facilitates the description of the individual’s awareness experience of internal states (e.g., perception, sensations, emotion, volition, or memories), thus helping us to better understand the relationship between the brain and mind. Although significant research has been aime [...]

by Fernando Cabo  and Isaac Aguaristi

Received: 01 September 2019;  Published: 05 March 2020;  doi: 10.21926/obm.icm.2001013

Several manual bodywork therapies that originated in Asia are related to the theory and practice of acupuncture and Traditional Chinese Medicine (TCM). One of the aims of these therapies is to stimulate specific points on the body called acupoints which are the same points in which needles are inserted in acupuncture. These manual therapies, however, vary in their interpretation and explanation of the theories of TCM, and even more so, in the practical way the stimulation is applied. The aim of this paper is to cla [...]

by Lucy Watts  , Joanna Smith  , Wilfred McSherry  , Michael Tatterton  and Alison Rodriguez

Received: 04 November 2019;  Published: 03 March 2020;  doi: 10.21926/obm.icm.2001012

In palliative and end of life care settings supporting people to make sense of their lives is as important as managing disease symptoms. Dignity Therapy is a validated psychotherapeutic intervention designed to bring about a sense of meaning and purpose for individuals at the end of life. Dignity Therapy has primarily been implemented and evaluated in adult palliative care settings. Prior to designing studies that evaluate Dignity Therapy for children and young people with life-limiting and life-threatening conditi [...]

by Tina Huang  , Tony Hung  , S. Irene Kim  and Ka Kit Hui

Received: 07 October 2019;  Published: 02 March 2020;  doi: 10.21926/obm.icm.2001011

Acupuncture has increasingly been used to address a variety of symptoms in patients with cancer. Here we present a case to illustrate the use of acupuncture in a 35-year-old female with metastatic breast cancer who presented to the UCLA Center for East-West Medicine (CEWM) with physical and psychological symptom clusters of insomnia, anxiety, and joint pain.

by Consuelo C. Casula

Received: 18 January 2020;  Published: 27 February 2020;  doi: 10.21926/obm.icm.2001010

This article is based on the assumption that the therapist's focused attention, open awareness and kind intention are the basic ingredients for creating a relationship of trust with the patient from the first session. He also stresses that when the attention of a genuine therapist, without prejudice or judgment, is centered on how the patient expresses him/herself and on the contents s/he proposes, the patient relies more easily on the competent care of the therapist. The author argues that to empower patients it i [...]

by Fengxia Liang  and Gerhard Litscher

Received: 25 February 2020;  Published: 26 February 2020;  doi: 10.21926/obm.icm.2001009

Traditional Chinese Medicine (TCM) has been used to prevent and alleviate epidemic diseases for hundreds of years. The combination of TCM and Western medicine can effectively reduce fever; alleviate cough, fatigue, diarrhoea and other symptoms of patients with mild COVID-19 (Coronavirus disease-19). For the treatment of moderate and severe syndromes, the integrative approach can reduce lung exudation and inhibit the further development of the disease. However the risk of infection is a limit for example in needle a [...]

by Danielle Gentile  , Danielle Boselli  , Matthew Flores  , Susan Yaguda  , Rebecca Greiner  , Paulomi Campbell  and Chasse Bailey-Dorton

Received: 31 October 2019;  Published: 21 February 2020;  doi: 10.21926/obm.icm.2001008

Literature suggests Oncology Massage (OM) reduces anxiety. However, research is limited in large, diverse, nonexperimentally manipulated outpatient samples of cancer patients. The purpose of this study was to 1) describe OM visit patterns, 2) describe anxiety response to OM, and 3) determine if OM resulted in significantly reduced anxiety at first visit, across all visits, and longitudinally over time controlling for demographic factors. From January 2015-June 2019, a cohesive, consecutive, retrospective sample eva [...]

by Donald Moss

Received: 20 January 2020;  Published: 19 February 2020;  doi: 10.21926/obm.icm.2001007

The face of illness has changed with progress in public health, immunizations, and antibiotic medication. Today, medical clinics are more likely to see patients with chronic illnesses, stress-related conditions, and complex bio-psycho-social conditions. This is a global trend, affecting patients worldwide, as Western lifestyle and diet have produced increases in chronic lifestyle-based disorders. Integrative medicine, which attends more fully to psychosocial dimensions of illness, appears to offer promise for today [...]

by Sheng-Chieh Lu  , Connie W. Delaney  , Mary Fran Tracy  , Chih-Lin Chi  and Karen A. Monsen

Received: 30 December 2019;  Published: 17 February 2020;  doi: 10.21926/obm.icm.2001006

Integrative health (IH) therapies are increasingly used to manage health conditions, but barriers hindering nurses from offering IH therapies persist. Informatics and artificial intelligence (AI) approaches have potential to promote nurses’ professional use of IH therapies. The purposes of this review are to (1) describe the state of the science of informatics and AI approaches promoting nurses’ use of IH therapies and (2) identify gaps in literature for future investigations. This systematic scoping review followe [...]

by Anupa Pathak  , Saurab Sharma  and Mark P. Jensen

Received: 30 December 2019;  Published: 05 February 2020;  doi: 10.21926/obm.icm.2001005

There is a growing body of research evaluating the effects of hypnosis for the management of clinical pain. A summary of the recent systematic review would help understand the quality of evidence regarding the efficacy of hypnosis, and provide directions for future research. We conducted a scoping review of systematic reviews and meta-analyses on the efficacy of hypnosis for management of clinical pain conditions published after 2013. We searched four databases and two reviewers independently screened studies. We e [...]

by Jean Youngwerth  , Heather Coats  , Amy Jones  , Angela Wibben  , Elizabeth Somes  , Sue Felton  , Ashley Anderson  , Kathleen Flarity  , Kellar Elliot  and Jean Kutner

Received: 17 November 2019;  Published: 14 January 2020;  doi: 10.21926/obm.icm.2001004

The University of Colorado Hospital (UCH) implemented a Creative Arts Therapy (CAT) program offering CAT to hospitalized patients as a component of comprehensive palliative care (PC) services. The objective of this pilot program evaluation study was to evaluate short-term effects of CAT on patient symptoms and patient/family perceptions regarding their experience. The sample included adult patients hospitalized in an academic medical center who were seen by the Palliative Care Consult Service (PCCS) between October [...]

by Yan Yang  and Gerhard Litscher

Received: 08 January 2020;  Published: 14 January 2020;  doi: 10.21926/obm.icm.2001003

Acupuncture, being a unique method, is a millennia-old tradition in the field of Chinese medicine. However, it is surprising that there are very few scientific publications on acupuncture and its gender-specific effects. This article summarizes the previous work from the perspective of both Western and Eastern medicine, involving manual acupuncture, electro-acupuncture, and modern innovative laser acupuncture. There is scientific evidence that future gender-specific considerations should be included in the assessme [...]

by Tara T. Lineweaver  , Suneeta Kercood  , Elyse B. Morgan  , Shelby L. Rampone  , Colleen C. Frank  , Scott A. McLuckie  and Mack F. Reed

Received: 27 October 2019;  Published: 07 January 2020;  doi: 10.21926/obm.icm.2001002

Past research suggests that exercise is associated with improved working memory (WM) abilities, and that athletes have better executive functioning and WM skills than non-athletes. However, no studies to date have separated the effects of exercise from the effects of athletic participation when examining WM. This study had three primary goals: (1) to determine whether amateur college athletes have better auditory and visual WM than their non-athlete peers who exercise frequently and whether non-athlete frequent exe [...]

by Thierry Provencher  , Jonathan Charest  and Celyne H. Bastien

Received: 09 October 2019;  Published: 02 January 2020;  doi: 10.21926/obm.icm.2001001

Neuroimaging evidences point to the role of hyperarousal in the pathophysiology of insomnia. While actual treatments fail to directly target brain hyperarousal, emergent complementary therapies known as neuromodulation techniques aim to improve sleep in people with insomnia by targeting irregularities in their brain activity. In this paper, we narratively review the most relevant studies reporting the application of neuromodulation techniques to improve sleep in individuals with insomnia. Using a non-systematic app [...]

by Simona Ruggirello  , Enrica L. Santarcangelo  and Laura Sebastiani

Received: 10 September 2019;  Published: 18 December 2019;  doi: 10.21926/obm.icm.1904066

Background: Hypnotizability is a psychophysiological trait associated with several differences including the level of functional equivalence (FE) between imagery and perception, i.e., the similarity of the cortical activations and network configurations associated with each of them. FE is stronger in high hypnotizability individuals (highs) than low hypnotizable participants (lows). In this framework, this study investigates the correlation between electroencephalogram (EEG) of imagined arm/hand movements (MI) and [...]

by Peta Stapleton  , Trude Roos  , Glenn Mackintosh  , Emma Sparenburg  , Debbie Sabot  and Brett Carter

Received: 14 October 2019;  Published: 17 December 2019;  doi: 10.21926/obm.icm.1904065

Background: The combination of dietary restraint and physical exercise as a recommended treatment for weight loss has had limited long-term success. One factor proposed as limiting weight management techniques efficacy is the failure to target psychological processes linked with overeating. Consistent with prior research that has identified the efficacy of emotional freedom techniques (EFT) in reducing food cravings and aiding weight loss, this pilot randomised controlled trial (RCT) examined the impact of online d [...]

by Lyndsie Koon  , Robert Brustad  and Megan Babkes Stellino

Received: 15 May 2019;  Published: 27 November 2019;  doi: 10.21926/obm.icm.1904064

Physical activity participation has been found to favorably influence cognitive function across the lifespan. Specific characteristics, or qualities, of physical activity involvement (e.g., type, intensity, level of cognitive demand) may yield particular benefits. The purpose of this study was two-fold. The first objective was to develop taxonomies for two physical activity characteristics of interest: the level of task complexity (motoric and cognitive) and the level of social engagement. The second objective was [...]

by Michael Frass

Received: 13 November 2019;  Published: 14 November 2019;  doi: 10.21926/obm.icm.1904063

Highlights of Application of Homeopathy in Oncology Patients: An Interview with Prof. Michael Frass

by Joseph V. Pergolizzi  , Aaron Tabor  , Jo Ann LeQuang  , Michael Annabi  and Hani Annabi

Received: 05 June 2019;  Published: 05 November 2019;  doi: 10.21926/obm.icm.1904062

Background: The ketogenic diet (KD) was developed in the 1920s as a treatment for pediatric epilepsy and is emerging as a possible treatment option for certain mental health disorders. There is a link between certain mental health disorders and epilepsy, suggesting some commonality among underlying mechanisms. Methods: The literature relating to mental disorders and the KD is sparse. The authors attempt to a narrative review of the existing literature to show that there may be validity to studying the KD as a treat [...]

by Sonia Baccetti  , Elisabetta Barbara Cortesi  , Maria Valeria Monechi  , Mariella Di Stefano  , Barbara Cucca  , Tommaso Conti  , Antonella Traversi  , Filippa Terranova  , Sylvie Yvonne Barberousse  , Roberto Montelatici  , Federica Sabatini  , Catia Vuono  , Christian Bini  , Elio Rossi  and Francesca Martella

Received: 27 September 2018;  Published: 25 October 2019;  doi: 10.21926/obm.icm.1904061

Background: Pain and vasomotor symptoms are the common side effects experienced by breast cancer patients undergoing conventional oncology treatments. Traditional Chinese Medicine might represent a key treatment option for these side effects in a multidisciplinary pathway. Aim: The present study with a retrospective design was aimed at confirming the effectiveness of acupuncture, plum blossom, and auriculotherapy in reducing hot flashes and the intensity and frequency of pain in women with breast cancer. Materials [...]

by Francesco Sivelli  , Elio Rossi  , Sonia Baccetti  , Mariella Di Stefano  , Eugenia Gallo  and Fabio Firenzuoli

Received: 27 September 2018;  Published: 18 October 2019;  doi: 10.21926/obm.icm.1904060

Phytotherapy, which is defined as the use of titrated herbal extracts in clinical practice, has been receiving increasing interest in the scientific community recently. In the present report, information regarding the most important mechanisms underlying the drug-drug interactions (DDI) and herb-drug interactions (HDI) has been discussed briefly. Furthermore, the best known and relevant interactions of Ginkgo biloba, Citrus paradisi (Grapefruit Juice), Silybum marianum (Milk Thistle), Hypericum perforatum (St. John [...]

by Myriam Rudaz  , Thomas Ledermann  , Michael P. Twohig  and Michael E. Levin

Received: 24 May 2019;  Published: 10 October 2019;  doi: 10.21926/obm.icm.1904059

Background: There is robust evidence that mindfulness trainings enhance mindfulness as operationalized in Western psychology, but evidence about their effect on aspects of heartfulness is sparse. The present study, therefore, sought to evaluate whether a brief mindfulness training enhances heart qualities, including self-compassion, gratitude, and the generation of feelings of happiness. Methods: Eighteen students enrolled in a mindfulness training that was offered as part of an interdisciplinary class. The trainin [...]

by Sarah Fogarty  and Phillipa Hay

Received: 06 August 2019;  Published: 08 October 2019;  doi: 10.21926/obm.icm.1904058

Background: Death is a universal human experience. The experience of grief is unique for each person experiencing it. There is emerging research on modalities that provide support for bereaved individuals including bereavement massage. There is limited information in the literature about the specific role that massage can play in supporting bereaved individuals. The aim of this scoping review is to explore the literature that reports on the use and outcomes of bereavement massage so that massage therapists, consume [...]

by Niamh Flynn

Received: 01 July 2019;  Published: 26 September 2019;  doi: 10.21926/obm.icm.1903057

Hypnosis interventions consistently produce significant decreases in pain associated with a variety of chronic-pain problems (Elkins, Jensen & Patterson 2007) while neurophysiological studies have shown that specific hypnotic suggestions have clear effects on the brain and spinal cord functioning (Jensen & Patterson 2014; Flynn, 2019). Thus, it isuseful for clinicians who practise hypnotherapy to understand pain paradigms.

by Kelly Armstrong  , Raman Gokal  and Todd Todorsky

Received: 25 March 2019;  Published: 25 September 2019;  doi: 10.21926/obm.icm.1903056

Background: Direct Current (DC) micro-current point stimulation (MPS) is increasingly recognized as a therapy for chronic pain and stress management. However, there remains limited evidence as to the therapeutic value of MPS in chronic post surgical pain (CPSP) management related to C-Section scars. Objectives: We aimed to determine the effect and magnitude that MPS has when applied to C-section scars and its effects on a wide variety of non-specific chronic post surgical pain syndromes. Study Design: This was a co [...]

by Thibault Deschamps

Received: 24 July 2019;  Published: 24 September 2019;  doi: 10.21926/obm.icm.1903055

Let’s consider the issues of exercise and cognitive function from a different angle, by moving from sitting to standing for instance. Not only does seeing anything from different perspectives reflect our cognitive flexibility [1], it also has a direct impact on the executive performance. Interestingly, recent studies reported a smaller Stroop effect when standing than when sitting [2-3] or after stepping backward [4], evidencing that the body posture enhances selective attention and cognitive control. Hence a call [...]

by Randolph James  , Amy Lawson Moore  , Dick M Carpenter II  , Terissa Michele Miller  and Christina Ledbetter

Received: 29 April 2019;  Published: 06 September 2019;  doi: 10.21926/obm.icm.1903054

Background: The current study examined a multifaceted anti-neuroinflammatory intervention that included physical exercise, mental exercise, grain-free/sugar-free diet, anti-inflammatory nutritional supplements, sleep optimization, and stress management within the context of a functional medicine practice for five patients with varying levels of cognitive impairment. Methods: In a prospective chart review, we examined impact measures including assessment of (1) cognitive skills, (2) brain connectivity, and (3) daily [...]

by Siti Hana Nasir  , Olga Troynikov  , Dawn Wong Lit Wan  and Zhen Zheng

Received: 25 February 2019;  Published: 02 September 2019;  doi: 10.21926/obm.icm.1903053

Background: Pressure and thermal therapy gloves are the two types of therapeutic gloves that are commonly used to relieve symptoms and improve hand function in patients with hand arthritis. However, no published clinical study exists indicating ideal pressure and thermal stimuli for the gloves. Understanding user thresholds for the pressure and thermal stimuli is crucial to improve therapeutic outcomes, wearer's comfort, and adherence to the therapy. There were two main aims of this pilot study, firstly to examine [...]

by Max Oberste  , Sophia Sharma  and Philipp Zimmer

Received: 24 April 2019;  Published: 28 August 2019;  doi: 10.21926/obm.icm.1903052

This systematic review and meta-analysis investigated whether acute aerobic exercise improves subsequent set shifting performance in healthy young individuals. Potential moderation of studies’ methodological quality and exercise intensity, as well as the presence of small-study effect was also examined. Studies were identified using electronic databases Medline, PsycINFO, and SPORTDiscus, as well as references of recent meta-analyses and references of included studies. In total, 12 studies were included into [...]

by Avneet K. Mangat  and Georg M. Schmölzer

Received: 07 June 2019;  Published: 20 August 2019;  doi: 10.21926/obm.icm.1903051

The incidence of Neonatal Abstinence Syndrome (NAS) is increasing due to more mothers using illicit drugs. This results in an increase in costs and resources for the healthcare system. Newborns with NAS might experience withdrawal symptoms that can cause pain, distress, and may potentially increase the risk of future health complications. It is therefore important to find effective treatments that can alleviate NAS. Various non-pharmacological treatments are used in conjunction with pharmacological treatments to re [...]

by Patricia Lynn Dobkin

Received: 14 May 2019;  Published: 07 August 2019;  doi: 10.21926/obm.icm.1903050

The author writes a genuine story using a narrative medicine writing style [1]. She relates how she applied mindfulness awareness and meditation practices to accompany her best friend, Abigail (Abigail is a pseudonym), who struggled through stages 3 and 4 breast cancer, including its noxious treatments and upsetting side effects. Clinical practice can be enhanced with narrative competence in that it helps the author recognize, interpret and be touched by patients’ stories, including all aspects of illness experienc [...]

by Ryan A. Williams  , Lorna Hatch  and Simon B. Cooper

Received: 29 April 2019;  Published: 02 August 2019;  doi: 10.21926/obm.icm.1903049

It is well documented that an acute bout of exercise has a positive effect on subsequent cognitive function in children and adolescents. However, the effect of: the exercise characteristics (i.e. intensity, duration and modality), the cognitive domain assessed, and moderating variables (such as the participant’s age, physical fitness and baseline cognitive abilities); all of which affect this relationship are poorly understood. Therefore, the purpose of this review is to examine the impact of these variables on the [...]