A Review of Practical Applications of Fluid Flow and Associated Heat Transfer Modeling in Wellbores
Abstract
1645 11958
A Review of Practical Applications of Fluid Flow and Associated Heat Transfer Modeling in WellboresAbstract
Investigations on two-phase gas/liquid flow in pipes have been under study for nearly six decades. These studies have significantly assisted in managing fluid flow in the wellbore and surface networks, leading to the separation of phases and transmission of oil and gas into the market. This study summarizes some of the main lessons learned in flow through wellbores. Besides understanding some of the fundamental principles, we focused on the practical items of interest: Conventional production scenarios for oil and [...] 1645 11958 |
Membranome Similarity between Glioblastoma Multiforme Cell Lines and Primary TumorsAbstract
Genes encoding for proteins associated with the plasma membrane, referred to as the membranome, have long been recognized to play an important role in the development and maintenance of glioblastoma multiforme (GBM). GBM cell lines are commonly used to mimic tumors for in vitro experiments, but the extent to which they resemble GBM tumors in relation to the membranome is unclear. The present study explores the resemblance of GBM cell lines to primary tumors regarding membranome expression. Gene expression data was [...] 1645 8070 |
Do Social Isolation and Loneliness Kill People with Alzheimer's Disease?by
Abstract
Patients with AD have shortened life expectancy than the general older population is well established. Loneliness may be another risk factor to consider if we wish to understand and improve the premature mortality of AD. 1644 10785 |
Versatility of Supported Gold Nanoparticles on Hydrotalcites used for Oxidation and Reduction Reactionsby
Abstract
Regardless of their size, supported gold nanoparticles are largely used for liquid-phase oxidation reactions. Small gold nanoparticles exhibit good performance during the reduction of organic compounds. The direct reduction of carboxylic acid to aldehyde is a famous and familiar reaction in the field of organic chemistry and is considered as one of the fundamental chemical transformations. Herein, we present Au/hydrotalcite, Au/MgO, and Au/Al2O3 systems as heterogeneous versatile catalysts to realize the oxidation [...] 1642 11010 |
The Cost-Effectiveness of Mindfulness-Based Interventions for Medical Students: A Scoping ReviewAbstract
This scoping review aims to understand the available research and the quality of evidence about the cost-effectiveness of mindfulness-based interventions when applied to the medical student context. There is considerable literature pertaining to the application of mindfulness-based interventions in this context. However, the links between cost and effectiveness need to be established to ensure the relative integrity of these therapeutic systems. The participants included in the study were medical students (undergra [...] 1642 8660 |
Palmitoylethanolamide for Neurological DisordersAbstract
Neurological tissue along with the cartilage remains one of the tissues that escapes human efforts of regeneration after injury. The human body, after an injury, can repair its tissues only to a certain extent that can help in recovering the function of organs. However, this is not the case in some organs, such as the brain and spinal cord. For a long time, basic medical science has been investigating the regeneration process that helps the human body, which is mainly through the pharmacological agents, proteins/ot [...] 1642 13067 |
An Approach to Fungal Diagnostics in Solid Organ Transplantationby
Abstract
The approach to diagnosing fungal infections following solid organ transplantation (SOT) is patient-specific. An assessment of an individual’s risk for particular infections, also understood as the pre-test probability, should guide appropriate diagnostic testing whereas diagnostic stewardship is needed to produce interpretable, actionable and cost-sensitive results. This review provides a cognitive framework for practitioners aiming to diagnose fungal infections in recipients of SOT, taking into consideration the [...] 1642 10859 |
Synthesis of Tris(arylphosphite)-ligated Cobalt(0) Complexes [Co2(CO)6{P(OAr)3}2], and their Reactivity towards Phenylacetylene and DiphenylacetyleneAbstract
The dinuclear complexes [Co2(CO)6{P(OAr)3}2] (1a, Ar = Ph; 1b, Ar = o-Tol) were prepared and reacted with PhC≡CH and PhC≡CPh to yield dimetallatetrahedranes [{(ArO)3P}(OC)2Co-Co(μ-RC≡CPh)(CO)2{P(OAr)3}] (3a, Ar = Ph, R = H; 3b, Ar = o-Tol, R = H; 3c, Ar = Ph, R = Ph; 3d, Ar = o-Tol, R = Ph). The main reaction of diphenylacetylene was accompanied by a side reaction, leading to the dissociation of a P(OAr)3 ligand for the formation of mono(phosphite) complexes [{(ArO)3P}(OC)2Co-Co(μ-PhC≡CPh)(CO)3] (2b, R = Ph; 2d, R [...] 1640 8712 |
Nanomedicine: Pioneering a New Frontier in Neuro-OphthalmologyAbstract
Nanotechnology is one of the most promising fields of study, and it represents a pioneering leap in science and technology by the precise control over materials at the atomic and molecular level. This transformation affects numerous aspects of modern human life, including medicine, healthcare, electronics, computing, and energy storage. Nanotechnology has shown significant advancements in managing various health problems through different nano-formulations. These engineered nano-systems can be used as drug delivery [...] 1640 7822 |
The Puzzle of Immunosuppressive DrugsAbstract
Kidney transplantation has become the preferred treatment option in end-stage chronic renal failure as it provides significant improvements over dialysis in terms of both quality and duration of life. Even after several randomized studies conducted in the last 20 years, the combination of CNI, MMF, and steroids continues to be considered the gold standard for kidney transplantation. However, novel molecules aimed at minimizing renal and cardiovascular toxicity, particularly with CNI sparing, are being identified. T [...] 1640 9962 |
Recycling Potential in the European Union (EU) of Low Voltage Three-Phase Induction Motors Up to 75 kW of Power: Quantitative AnalysisAbstract
This article quantifies the recycling potential of the metallic materials that make up three-phase induction motors. The data on the use of electric motors by type and power determines that the most significant recycling potential lies in this low-voltage motor which powers up to 75 kW. The work aims to show the possibility of such recycling in the European Union (EU). The metals used to make the various parts of the induction motor and the main recycling methods that allow their reuse are listed. It evaluates whic [...] 1639 9387 |
Treating Dementia Early: Limiting Cellular Damage in Brain TissueAbstract
Much evidence has been published which indicates that microvascular endothelial dysfunction, due to cerebrovascular risk factors (e.g., atherosclerosis, hypertension, obesity, diabetes, smoking, aging), precedes cognitive decline in Alzheimer's disease and contributes to its pathogenesis. By incorporating appropriate drug(s) into biomimetic (lipid cubic phase) nanocarriers, one obtains a multitasking combination therapeutic which targets certain cell-surface scavenger receptors, and crosses the blood-brain barrier [...] 1639 9673 |
Automated Probabilistic Analysis and Parametric Modelling of the Seasonal-Diurnal Wind VectorAbstract
A refined and extended version of the Offset Elliptical Normal mixture model has been developed to parameterise the seasonal diurnal wind vector automatically. Automated using R scripts, the method eliminates any potential risk of confirmation bias posed by the manual supervision in the original method. Refinements to the method include the latest algorithms for clustering of Gaussian mixtures, with Bayesian regularisation to set the number of components and to limit the predisposition to overfit. A new extension u [...] 1639 9072 |
Ectopic Pelvic Kidney with Anomalous Vascular Supply during Deceased Organ Procurement – Case ReportAbstract
Even though renal ectopia is common, there have been very few reports of these kidneys being used for transplantation. The concerns with using such kidneys are subnormal function, ureteral anomalies and complications and anomalous arterial supply which makes arterial reconstruction challenging. Majority of reports are for use in living donor transplantation where good preoperative imaging is available. There is very scant literature reporting use of ectopic pelvic kidneys from deceased donors. We report a case of a [...] 1639 9209 |
The Effects of Loneliness on the Aged: A Reviewby
Abstract
Social support has been shown to have many positive effects on our lives, health, and ability to grow and flourish. Lack, or diminished social support results in loneliness. This thematic review focuses on the elderly, and the loneliness that is part of the life of many of them. The review highlights the social connections and the expectations that the elderly may have of them, and how being connected to others may alleviate, loneliness. Loneliness is known to negatively affect one’s health, social life, familial r [...] 1637 14038 |
Adsorption of Rhodamine-B (RhB) and Regeneration of MCM-41 Mesoporous Silicaby
Abstract
Rhodamine (RhB) adsorption was carried out on MCM-41 and MCM-41 calcined. The effect of parameters such as pH was investigated. The reusability potential of MCM-41 was also established and the mechanism of RhB adsorption was discussed. MCM-41 was synthesized and calcined, with all samples characterized by X-Ray Diffractometry, X-ray Fluorescence by Dispersive Energy, Infrared Spectroscopy, Scanning Electron Microscopy, and Thermogravimetric analysis. The results of the characterization techniques performed confirme [...] 1636 11798 |
Teachers’ Perceptions of Integrating Tower Gardens into Pre-K4 CurriculumAbstract
Schools play an integral role in providing opportunities for children of all ages to be exposed to nutrition education. There are a variety of ways children can receive nutrition education in the school setting, such as explicit lessons, modeled dialogue, and exposure to nutrition-based principles. However, there continues to be a disconnect between teacher perceptions of nutrition education and time spent implementing it in the classroom. Nutrition education can come in many forms, including hands-on gardening and [...] 1636 9158 |
Advances in Nanocarriers for Drug Delivery in Dental TherapiesAbstract
Dental caries are one of the major causes of oral degeneration diseases. In order to treat dental-related diseases, it is often challenging and expensive. Recent literature has reported many advances in designing delivery systems utilizing polymers and novel biomaterials. Polymers play an important role in designing many nanoformulations like liposomes, polymeric micelles, polymeric nanoparticles, carbon-based nanoparticles, nano-hydroxyapatite, iron oxide, zirconia, silica, and silver nanoparticles were used to tr [...] 1635 12042 |
Impact of Pt-Ni Nanoparticle Architecture on Electrocatalytic Oxidation Reaction in Fuel Cellsby
Abstract
This paper investigates how the aggregation of bimetallic nanoparticles (NPs) influences the electronic condition of the surface adsorption site and, hence, the performance of materials during the electrooxidation of fuels in an alkaline medium. First, we synthesized Pt-Ni NPs in three configurations: ordered intermetallic, ordinary alloy, and core-shell. The NPs contained Pt and Ni close to a 1:1 Pt/Ni atomic ratio. They had similar particle sizes, which allowed us to evaluate their performance without the influen [...] 1634 8452 |
Net Zero Corridors: A Case Study Approach from Perth, Australia to Decarbonize Urban Power and Transportby
Abstract
The transition to net zero cities is a pivotal challenge in the face of climate change. This research introduces a novel methodology termed "Net Zero Corridors," which emphasizes a bottom-up approach to decarbonize urban power and transport systems. By focusing on urban corridors, this method integrates distributed power systems with urban transport, offering a localized solution to the broader challenge of urban decarbonization. Drawing from urban fabric theory and urban metabolism data, the study provides insight [...] 1634 9692 |
Effect of Microwave Radiation on the Development of a Porous Aluminum Carrier of the Active Mass of Catalysts in Heterogeneous Catalytic ReactionsAbstract
In this study, we prepared a fine-grained, aluminum-reinforced alumina support matrix of the active mass of catalysts, which showed activity in heterogeneous catalytic reactions stimulated by electromagnetic radiation in the microwave range. The support absorbed microwave radiation of 2.45 GHz. We compared the textural characteristics of samples of Al/Al2O3 supports obtained by conventional heat treatment to those synthesized by heat treatment in a microwave field. We found several advantages of heat treating poten [...] 1633 7390 |
Unexpected Associations between the Number of FRAXE Repeats in Boys and Evidence of Diabetes in Their Mothers and Maternal Grandmothersby
Abstract
The FRAXE section of the FMR2 gene, located on the X chromosome, contains varying numbers of trinucleotide repeats; boys with over 200 repeats tend to have mild cognitive impairments, though this is rare. Little is known, however, concerning the phenotypes of individuals with smaller numbers of repeats. Here we answer the research question as to whether the health of ancestors of boys from whom the relevant X chromosome was inherited differed in any way according to the number of FRAXE repeats. Numbers of FRAXE rep [...] 1633 10505 |
Hematopoietic Stem Cell Transplantation in Refractory Celiac Disease: An Overview with Focus on Infectious Complicationsby
Abstract
Refractory celiac disease (RCD) is a rare condition in which a known celiac patient, usually an adult, suffers from persistence or recurrence of gluten-related symptomatology, laboratory abnormalities, and inflammatory enteropathy despite following an optimal dietary therapy with gluten-free diet (GFD). Arbitrarily, a duration of at least 12 months of GFD has been recommended prior to establishing such a diagnosis. Furthermore, exclusion of the other possible causes of non-celiac villous atrophy, particularly enter [...] 1633 11641 |
Views of Conventional Medicine and Integrative Medicine among Informal Dementia Caregivers and Healthcare Professionals in NW EnglandAbstract
The urgent need for innovative approaches to dementia treatment that are acceptable, effective and affordable underlies this research. Growing evidence supports ‘integrative medicine’ as a potential treatment approach aligned with and including conventional medicine. However, success will depend on addressing barriers, recognising needs of diverse communities and involving people in co-creating desired interventions. The three aims of this study were to, 1) describe conventional allopathic medicine and integrative [...] 1632 12949 |
Bacteriophages Therapy: Exploring Their Promising Role in Microbiome Modulation and Combatting Antibiotic ResistanceAbstract
Bacteriophages, or phages, are viruses that infect bacteria, exhibiting specificity towards particular bacterial strains. Despite being overshadowed by traditional antibiotics in the West, interest in phage therapy has resurged due to the escalating antimicrobial resistance crisis. Understanding phage biology, selection, production, and pharmacology is crucial for their clinical application. Phages interact intricately with the human microbiome, influencing bacterial populations and potentially offering therapeutic [...] 1630 10180 |
Translation and Validation of “Brief Bedside Dysphagia Screening Test” in a Greek Sample of Neurological Patientsby
Abstract
Dysphagia may become a threatening condition if not diagnosed and treated at an early stage. Healthcare professionals require simple, rapid, and reliable tools for the immediate evaluation of dysphagia in their daily clinical practice. The aim of the present study was the translation and validation of the “Brief Bedside Dysphagia Screening Test-Revised (BBDST-R)” tool in the Greek language in a sample of patients with neurological disorders. The present study was designed as a cross-sectional study cond [...] 1630 9323 |
Examining the Psychometric Properties of the Compassionate Engagement and Action Scales (CEAS) in the UK General PopulationAbstract
Research has shown that compassion – whether to others, from others or to oneself – can be associated with improved well-being and mental health. Most measures to date focus on one of these flows of compassion, with only one recently published scale tracking all three. The primary aim of the current study was to investigate the psychometric properties of The Compassionate Engagement and Action Scales (CEAS) in a UK sample. The secondary aims were to investigate the level of compassion, as measured by th [...] 1630 10454 |
Validation of the Insomnia Severity Index among University Students in Koreaby
Abstract
Insomnia is the most common sleep complaint in clinical practice, affecting both the physical and mental health of patients as well as many aspects of their life quality. Young adults, especially university students, are prone to a high prevalence of poor sleep quality or insomnia. Accurate assessment of insomnia severity among university students has become an important issue. One promising screening tool to identify clinically significant insomnia in the campus setting is the Insomnia Severity Index (ISI), a seve [...] 1630 12751 |
Hot Water Preparation along with Combined Solar Thermochemical Energy Storage System: Experimental Validation and Performance SimulationAbstract
Hybrid solar thermal systems are considered to be a promising solution for delivering clean thermal energy for the building sector, especially while combining them with other renewable energy sources. Usually, solar energy production does not match the thermal energy demand, and hence the energy storage must be integrated. Thermochemical energy storage is adapted particularly to be used along with solar thermal applications. In this article, the design of the combined solar thermochemical energy storage system is p [...] 1629 9288 |
Electrochemical Synthesis of Germanium-Polypyrrole Composite Nanomaterials in Ionic Liquids for the Fabrication of Lithium-Ion BatteriesAbstract
Herein, we report the coating of nanostructured germanium using a polypyrrole (PPy) polymer coat as a composite anode material for the fabrication of lithium-ion batteries. The Ge/PPy composites were synthesized following the direct electrochemical deposition method in an ionic liquid (IL). The results revealed that the coating of PPy on Ge helped realize stable battery cycling and reversible capacities, which were not observed in uncoated Ge. The PPy layers could effectively inhibit side reactions between the elec [...] 1629 10999 |
A Simple and Effective Non-Human Primate Diabetic Model Combining Sub-Total Pancreatectomy and Low-Dose Streptozotocin Injectionby
Abstract
Background: The existing non-human primate diabetic models, particularly those induced by total pancreatectomy or streptozotocin (STZ) injection, have several disadvantages, including a lengthy surgical procedure, the need for continual supplementation of digestive enzymes, and delayed oral intake after total pancreatectomy, and severe hypoglycemia and hepatic/renal toxicity following injection of high-dose STZ. This study aimed to develop and optimize a non-human primate diabetic model that would avoid the disadva [...] 1629 11962 |
“Real World” Australian Experience of Allogeneic Hematopoietic Stem Cell Transplantation (HSCT) in Adults with Severe Aplastic Anaemia.by
Abstract
Acquired Severe Aplastic Anaemia (SAA) is a rare bone marrow failure syndrome, for which allogeneic haematopoietic stem cell transplant (HSCT) is a proven curative therapy. Despite excellent outcomes for matched sibling SAA recipients in terms of engraftment and survival, HSCT remains highly challenging in older matched-unrelated-donor (MUD) recipients, due to increased non-relapse mortality (NRM) from causes such as graft versus host disease (GVHD), organ failure and infection. We sought to evaluate our local HSCT [...] 1629 9354 |
Loneliness or Solitude: How Are They Different?by
Abstract
Loneliness, social isolation, aloneness, and solitude may be used interchangeably by some who may miss the difference between them. Loneliness is the experience of being alone, or perceiving that one is alone and unimportant to others. Solitude is being geographically isolated out of one’s choice. Loneliness is not a feeling, but a multidimensional construct which is expressed cognitively, behaviorally and affectively. solitude is also reviewed and a clear distinction between loneliness and solitude is established. [...] 1628 10455 |
Automated Quality and Process Control for Additive Manufacturing using Deep Convolutional Neural Networksby
Abstract
Additive Manufacturing (AM) is a crucial component of the smart manufacturing industry. In this paper, we propose an automated quality grading system for the fused deposition modeling (FDM) process as one of the major AM processes using a developed real-time deep convolutional neural network (CNN) model. The CNN model is trained offline using the images of the internal and surface defects in the layer-by-layer deposition of materials and tested online by studying the performance of detecting and grading the failure [...] 1628 12886 |
New Frontiers in Solid Organ Transplantation from Donors with Human Immunodeficiency Virus, Hepatitis C Virus Infection, and Multidrug Resistant Organismsby
Abstract
Despite the advances that have been made in the field of solid organ transplant (SOT), organ shortage remains a persistent problem. In addition, the donor pool has been changing with the ongoing opioid epidemic and increase in deaths related to drug overdose each year. More donors are meeting the 2013 United States (U.S.) Public Health Service criteria for increased risk donors (IRDs), or donors who are at higher risk for transmission of Human Immunodeficiency Virus (HIV), Hepatitis C virus (HCV), and other multidr [...] 1628 8875 |
Donor Derived Strongyloidiasis in a Lung Transplant Recipient: From Life Cycle to Hyperinfection Syndromeby
Abstract
Strongyloides stercoralis infection derived from the donor in solid organ transplant (SOT) places recipients at risk for hyperinfection syndrome and death. We describe the case of a lung transplant recipient who developed strongyloidiasis presenting with GI symptoms and progressing to diffuse alveolar hemorrhage, bacteremia and multi-organ failure. The patient's clinical course illustrates the life cycle of Strongyloides. For treatment, the patient received ivermectin and albendazole. We advocate that early diagnos [...] 1628 9526 |
Cost-Effective Biodiesel Synthesis from Waste Marble Powder as A Green Heterogeneous Catalyst Using Pongamia Pinnata Oilby
Abstract
Waste marble powder (WMP) is Investigated for developing heterogeneous catalysts by calcination method and used in biodiesel synthesis by esterification-transesterification process from Pongamia Pinnata oil. Hammet indicators, Fourier transform infrared (FT-IR), Thermogravimetric analysis, and X-ray powder diffraction (XRD) techniques were also studied for the characterization of developed catalyst from waste marble powder (WMP). The conversion of calcium carbonate to calcium oxide in marble powder was found at 800 [...] 1626 10196 |
Positive Aging a Two-Way Street: Healthy Lifestyle and Attitudes of OthersAbstract
Background: Previous research has indicated the attitudes that others have toward older adults play an important role in their well-being. The current study contributes to the literature because it evaluates attitudes toward older adults. Methods: The participants included Caucasian and Indigenous people residing in Northern Ontario. All participants were asked to complete a demographics questionnaire and the Kogan’s Attitudes Toward Old People Scale (KAOP). Results: Results indicated that Indigenous participants h [...] 1626 9613 |
A Rechargeable Aqueous Lithium-Air Battery with an Acetic Acid Catholyte Operated at High Pressureby
Abstract
Acidic aqueous lithium-air batteries are attractive candidates for use as energy sources in electric vehicles because of their high energy and power densities and ability to operate under ambient conditions. An aqueous lithium-air battery with an acetic acid catholyte has a high theoretical energy density of 1,478 Wh kg-1, and the reaction product is soluble in the catholyte. In this study, we have studied the cell performance of a Li/interlayer electrolyte/NASICON-type solid lithium-ion conductor/acetic acid catho [...] 1626 12512 |
Improving the HealthCare of People with Dementia beyond the Diagnosis: The “Carlo Poma Dementia Care Pathway” Study Protocolby
Abstract
The WHO global action plan on the public health response to dementia 2017-2025 stressed the need to have a comprehensive approach with deep interconnections and cross-cutting elements through several action areas. As the elderly population grows worldwide, the number of patients with dementia increases rapidly because age is an important risk factor for developing late-onset dementia. Currently, dementia syndrome represents a true emergency. Once a diagnosis of dementia was made, informal caregivers, patients and t [...] 1625 13837 |
Barley and Malt as Base Ingredients for the Production of New Bio-Functional FoodsAbstract
This work aimed to evaluate the chemical composition, bioactive compounds (phenolics and γ-aminobutyric acid, GABA), and antioxidant properties of different barley varieties (Overture, Charles, Sinfonía, Montoya, and Andreia) and their malts to weigh up them as potential ingredients for producing new bio-functional foods. For this, five barleys and five malts obtained from them were studied. Regarding chemical composition, total starch was the main component (≈62%) of barleys followed by total di [...] 1624 11424 |
Where’s Waldo? Extrahepatic Site Options for Islet Transplantationby
Abstract
The current predominant location for allo- and auto-transplantation of islets is the liver. Despite the historical success of this site, recent studies have revealed multiple disadvantages. Portal hypertension, portal vein thrombosis, bleeding, low oxygen tension, instant blood mediated inflammatory reaction, inadequate alpha cell function, and delays in neovascularization are factors that continue to drive researchers to explore alternative sites for islet transplantation. Factors of an optimal site include: capac [...] 1624 11291 |
Promoting College Student and Staff Well-being Through a Mindfulness-based Coping ProgramAbstract
This study evaluated the impact on student and staff well-being of a mindfulness-based cognitive-behavioral coping program, Be REAL (Resilient Attitudes & Living), delivered by campus staff using a task-sharing approach. The program was adapted for online delivery during COVID19. Study participants included 325 undergraduate students and 100 staff members at a large tri-campus university in the U.S. Participants completed surveys with self-report measures assessing mindfulness, perceptions of stress, emotion regula [...] 1623 11826 |
Inclusion of Dietary-Fibers in Nutrition Provides Prebiotic Substrates to Probiotics for the Synthesis of Beneficial Metabolites SCFA to Sustain Gut Health Minimizing Risk of IBS, IBD, CRCby
Abstract
Usually, everyday meals constitute materials and ingredients for food preparation derived from different agricultural sources. Although most customers are aware of the benefits of a balanced diet, they mainly focus on a diet based on the daily requirements of protein, fat, and carbohydrates in their meals. However, the vital aspect of the including dietary fibers in diets is overlooked, which is equally important as is the daily requirement of calories and protein intake for maintaining the muscle mass. Some societ [...] 1623 11520 |
Delayed Clinically Significant Portal Hypertension after Total Pancreatectomy-Islet Auto-TransplantationAbstract
Portal hypertension often occurs transiently with injection of islet cells into the portal system during total pancreatectomy-islet autotransplantation (TPIAT). We describe a TPIAT patient with non-cirrhotic portal hypertension (NCPH) two years after surgery initially identified with esophageal varices on upper endoscopy. The underlying mechanism for the development of NCPH after TPIAT is unclear but infectious and immune-related pathways have been proposed. Management of NCPH is primarily treatment of complication [...] 1623 10926 |
Donor Cell-Derived Acute Myeloid Leukaemia with 3q26.2 Involvement/MECOM Rearrangement ‐ A Case Report and Literature Reviewby
Abstract
Donor cell-derived leukaemia (DCL) is an uncommon complication of allogeneic hematopoietic stem cell transplantation (HSCT). DCL might represent up to 5% of the post-HSCT disease relapses, but case numbers reported in the literature might underestimate the frequency. The leukemogenesis of DCL is not well understood due to the limited numbers of cases reported and lack of detailed molecular genetic information from recipients and donors. Although many theories have been proposed for leukemogenesis of DCL, the underl [...] 1623 9647 |
Compassion in Medicine – A Psychiatric Physician’s ViewAbstract
There are several definitions of sympathy, empathy, and compassion on the internet. I have chosen the above definitions to emphasize their salient differences, for the following reason: In medical school, in the early 1960s, we were taught not to sympathize with patients, but to empathize: By empathizing, one can retain some professional objectivity toward the patient, in order to be of some help. To sympathize, on the other hand, was to immerse oneself in the patient’s suffering and lose one’s professional per [...] 1622 8177 |
Right Heart Failure in Left Ventricular Assist Device Patientsby
Abstract
Left ventricular assist devices (LVADs) improve quality of life in end-stage heart failure patients but a frequent complication is Right heart failure (RHF) causing significant morbidity and mortality. This review article discusses key issues that need to be considered in the assessment and clinical management of RHF in LVAD patients including the use of Right Ventricle (RV) support devices and off-label LVADs as temporary or permanent RV support. 1622 14888 |
Examination of PCDD/F Formation in Thermal Systems Using Simple Mathematical ModelsAbstract
A set of empirical models which accounts for the formation of gas phase polychlorinated dibenzo-p-dioxins and furans (PCDD and PCDF), and solid phase PCDD/F by the de novo mechanism is described.In each case, competing formation and destruction reactions are considered to operate.The effect of the time-temperature history on their formation is then examined.At high temperatures, steady-state is reached in fractions of a second, resulting in the observed low product concentrations.Rapid cooling as found in furnaces [...] 1621 12941 |
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