by Yohanes Ridora  , Niken Trisnowati  and Retno Danarti

Received: 05 February 2024;  Published: 19 April 2024;  doi: 10.21926/obm.genet.2402229

Xeroderma pigmentosum (XP) is a rare genodermatosis characterized by increased sensitivity to ultraviolet radiation, leading to severe skin manifestations and a higher risk of early-onset malignancies. Previous studies from temperate climate countries with sound economic levels showed adequate photoprotection compliance among pediatric XP patients. However, no studies have assessed photoprotection compliance among children with XP living in tropical and low-economic settings. This article reports a low photoprotect [...]

by Anna Passaro  , Antonio Zullo  , Mariacarla Di Gioia  , Mirella Dragone  , Khalida Akbar  and Fabrizio Stasolla

Received: 30 May 2024;  Published: 15 August 2024;  doi: 10.21926/obm.neurobiol.2403240

The management and treatment of challenging behaviors in children diagnosed with Autism Spectrum Disorder (ASD) is a priority for caregivers, educators, and healthcare professionals. This selective review examined how different technologies were used to help manage challenging behaviors in children with autism, describing each technology's strengths, weaknesses, and applications. This paper aimed to provide accessible choices for caregivers, educators, and healthcare professionals, enabling them to make well-inform [...]

by OBM Transplantation Editorial Office

Received: 09 October 2022;  Published: 17 October 2022;  doi: 10.21926/obm.transplant.2204167

by Alastair C. Gray  , Parker Pracjek  , Christine D. Luketic  and Denise Straiges

Received: 03 September 2024;  Published: 09 December 2024;  doi: 10.21926/obm.icm.2404069

Research into the uptake profile and usage of Homeopathy has hitherto tended to be buried amongst complementary medicine research. Despite high levels of uptake of homeopathy, and robust numbers of over-the-counter sales of homeopathic products the current evidence evaluating the uptake of homeopathy remains limited on several fronts. The aim of this study is to explore the basic demographic features and characteristics of users of homeopathy services. The setting is a student teaching tele-health facility based in [...]

by Boram Lee  and Hyelin Jeong

Received: 13 April 2023;  Published: 07 August 2023;  doi: 10.21926/obm.neurobiol.2303177

The COVID-19 pandemic and its associated disruptions have significantly impacted university students’ lives worldwide. The COVID Stress Scale (CSS) is a 36-item self-reporting instrument designed to measure stress caused by the COVID-19 pandemic. This study purposed to examine the psychometric properties of the Korean version of the CSS for use with Korean university students. The study sample comprised 402 undergraduate students enrolled in a four-year private university in central South Korea. This cross-sectiona [...]

by Yusuke Kataoka

Received: 25 October 2022;  Published: 06 April 2023;  doi: 10.21926/aeer.2302026

Understanding the urban environment and the health status of residents is necessary for appropriate administrative services and regional management. This study used indicator scores derived from the area statistics of cities in the Tokyo metropolitan area to identify factors that affect health status. Indices were classified into two groups: health-related and non-health-related. The index values of each group served as the observed variables and were statistically standardized. The relationship between the two gro [...]

by Rolf Teschke  and Axel Eickhoff

Received: 08 January 2025;  Published: 14 February 2025;  doi: 10.21926/obm.transplant.2501234

Liver transplantation (LT) can be the only option for patients with acute liver failure (ALF) where medical approaches are ineffective. Causes of ALF are multiple and commonly easily detectable, but uncertainty remained on the role of drug-induced liver injury (DILI) within the published ALF cohorts. Therefore, an analysis was undertaken to clarify which drugs may have caused the DILI and how the diagnosis of the liver injury was established. Using the PubMed database and Google Science, the search term of acute li [...]

by Olubunmi Yemisi Fashoto  , Maureen Nokuthula Sibiya  and Olanrewaju Oladimeji

Received: 09 July 2024;  Published: 08 November 2024;  doi: 10.21926/obm.neurobiol.2404253

The availability and utilization of digital technologies can leverage the challenges of the sharp-depleting workforce due to the consistent migration of healthcare professionals (HCPs), the alarming ratio of the number of patients to HCPs, discretional use of digital technologies among HCPs in providing effective therapeutic interventions and mental healthcare services. This study aimed to develop an operational model that integrates digital technologies in mental healthcare service delivery for public facilities i [...]

by Dorcas N. Magai  and Hans M. Koot

Received: 29 May 2024;  Published: 29 November 2024;  doi: 10.21926/obm.icm.2404068

This cross-sectional study addressed the association between parental and family characteristics as risk factors for emotional and behavioral problems (EBP) and quality of life (QoL) and the potential moderation of these associations by adolescents' characteristics. A total of 533 households from Central Kenya with adolescents between 12 to 18 years (median age 15 years) and their mothers (or female caregivers) were included in this study. Adolescents and their mothers completed questionnaires on parent and family [...]

by John A. T. Bye

Received: 13 November 2022;  Published: 05 February 2023;  doi: 10.21926/aeer.2301018

This paper presents a model for the similarity structure of the velocity profiles in air and water in the wave boundary layer, which provides predictions in terms of two parameters, F and R, of all its important properties, including the Charnock parameter, the surface drift velocity and the condition for the cancellation of the surface Stokes velocity by the surface current. The parameter, F, arises from the fetch variability of the wave field, and the parameter, R, arises from the duration variability of the wave [...]

by Richard J. Bloomer  , Alice Raphael Karikachery  , Velaphi C. Thipe  , Kavita K. Katti  , Kattesh V. Katti  , Mysore R. Harsha  , Vadakkanchery V. Vaidyanathan  , Caleb M. Schmidt  , Michael A. Schmidt  , Niraj A. Arora  , Bradley J. Ferguson  and Alton Michael Chesne

Received: 31 January 2025;  Published: 25 July 2025;  doi: 10.21926/rpn.2503014

Efficient glucose uptake by peripheral tissue is important for individuals who desire to maintain optimal wellbeing. Various methods to regulate postprandial blood glucose have been reported in the research literature, however, few have examined the effect of ketone esters on blood glucose levels. The present study evaluated blood glucose following the administration of an oral glucose tolerance test, with and without ketone esters delivered at two different dosages, in a sample of healthy Sprague-Dawley rats. We h [...]

by Irina V. Tarasova  and Olga A. Trubnikova

Received: 02 November 2023;  Published: 19 March 2024;  doi: 10.21926/obm.neurobiol.2401215

Postoperative cognitive dysfunction (POCD) has been observed as a complication after cardiac surgery consistently. The ineffectiveness of current treatments for POCD is causing a search for non-invasive alternatives. The present review aims to consolidate the current understanding of how VR methods effectively facilitate the recovery of cognitive functioning in cardiac surgery patients. To obtain information about the effects of VR technology on cognitive functions, we investigated the PubMed, Scopus, and Web of Sc [...]

by Recent Progress in Materials Editorial Office

Received: 11 April 2022;  Published: 14 April 2022;  doi: 10.21926/rpm.2202007

An Interview with Prof. Vincenzo M. Sglavo.

by José A. Cedeño-Escudero  , Luis A. Sotillo-Bent  , Carolina Vega- Cuellar  , Rolando González-Angulo  , Evelyn Medina-Batista  , José Sotillo-Lindo  and Luis A. Méndez-Rosado

Received: 13 August 2024;  Published: 12 October 2024;  doi: 10.21926/obm.genet.2404266

Hypertrophic cardiomyopathy (HCM) is the most common inherited cardiomyopathy, affecting approximately 1 in 500 people. It is the most common genetic cardiomyopathy inherited as a Mendelian trait in approximately 50% of patients, mainly due to pathogenic variants in genes encoding sarcomeric proteins. Mutations in the sarcomeric protein filamin C (FLNC) gene, with a cytogenetic localization on 7q32.1, have been linked to hypertrophic cardiomyopathy, as they have been determined to increase the risk of ventricular a [...]

by Vladimir N. Gorchakov  , Kirill M. Nicolaychuk  , Olga V. Gorchakova  , Georgi A. Demchenko  and Bayan A. Nurmakhanova

Received: 09 July 2023;  Published: 01 November 2023;  doi: 10.21926/obm.geriatr.2304257

Lymph nodes are prioritized in protecting and ensuring endoecological safety at different periods of life, especially in retirement age. It destabilizes the structure and function of the lymphatic system and organs when aging increases the risk of comorbid conditions. This is a sign of age-related pathology. Improving lymph node function is an essential task in integrating gerontology and lymphology. The solution to this problem is possible with the help of a phytotherapeutic agent, which involves the evaluation of [...]

by Joseph S. D'Arrigo

Received: 26 June 2022;  Published: 19 December 2022;  doi: 10.21926/obm.icm.2204054

The cardiovascular risk factors for dementia trigger widespread inflammation and oxidative stress. These two interacting processes lead to neurodegeneration, gradual cognitive/memory decline, and eventually (late-onset) dementia. In addition, there is supporting evidence pointing to elevated pulse pressure as a clear risk factor for cognitive decline. Accordingly, an effective therapeutic strategy to delay dementia could be based upon nanotargeting bioactive molecules, using lipid nanocarriers, toward cell-surface [...]

by Brittany Montgomery  , Calvin Mammen  and Matt Golden

Received: 18 October 2024;  Published: 09 May 2025;  doi: 10.21926/obm.geriatr.2502311

Assistive technology (AT) interventions have shown promising results in supporting cognitive, social, and physical activities in persons living with dementia (PLWD) and their caregivers. Despite strong evidence of the effectiveness of AT, PLWD and their caregivers can disengage with the technology after it is used for a time – i.e., the “stickiness challenge”. Diminished use of AT reduces the opportunity for it to have optimal impact. We asked whether the opportunity to engage in cognitive games may enhance continu [...]

by Fatimazahra Smaili  , Khawla Zerrouki  , Fatima Ezzahra Aouni  , Ayad Ghanam  , Maria Rkain  , Abdeladim Babakhouya  and Mariam Tajir

Received: 04 October 2024;  Published: 04 February 2025;  doi: 10.21926/obm.genet.2501283

Dystrophinopathies are genetic muscular disorders with recessive inheritance linked to the X chromosome due to mutations in the dystrophin gene, the DMD gene located in Xp21. The best-known forms are Duchenne muscular dystrophy (DMD) and Becker muscular dystrophy (BMD). Our study aims to determine the molecular profile and genotype/phenotype correlations of dystrophinopathies in the eastern region of Morocco. We report patients referred for 4 years (2020-2023) to the Medical Genetics Laboratory of the Mohammed VI U [...]

by Andrés R. Latorre-Rodríguez  , Devika Sindu  , Sumeet K. Mittal  and Ashwini Arjuna

Received: 23 February 2024;  Published: 21 June 2024;  doi: 10.21926/obm.transplant.2402219

Activated pepsin (pepA) in bronchoalveolar lavage (BAL) fluid may be a biomarker of gastric aspiration. We sought to i) evaluate the association of pepA in BAL fluid with acute cellular rejection (ACR) in a cohort of lung transplant recipients (LTRs), ii) assess the association between pepA and isolation of typical gastrointestinal microorganisms from BAL fluid, and iii) explore the accuracy of using pepA concentration as a biomarker of ACR. After IRB approval, we conducted a retrospective observational study analy [...]

by Mohammad-Reza Ghasemi  , Maryam Mirahmadi  , Hadi Bayat  , Morteza Sheikhi Nooshabadi  , Sanaz Jamshidi  , Shadab Salehpour  , Reza Mirfakhraie  , Fatemeh Fazeli  , Mohammad Miryounesi  and Milad Gholami

Received: 22 November 2024;  Published: 14 April 2025;  doi: 10.21926/obm.genet.2502291

Knobloch Syndrome (KS) is a rare genetic disorder characterized by ocular abnormalities and central nervous system (CNS) defects, which are attributed to collagenopathy. The primary gene implicated in KS is COL18A1, which encodes the alpha chain of type XVIII collagen. This type of collagen functions as a proteoglycan, predominantly located in the basement membrane of human tissues. This study examined an Iranian female presenting with symptoms of horizontal nystagmus, strabismus, and suspected vision loss, with a [...]

by Zongqi Guo  and Wenxu Wei

Received: 12 January 2024;  Published: 12 April 2024;  doi: 10.21926/rpm.2402010

Ceramic bonds are conventionally formed during the burning of refractory bricks and by using pre-fabricated blocks or monolithic lining, which is characterized as the coalescence of the particles by liquid sintering. However, the whisker bond was discovered with the outstanding performance of unburnt periclase–spinel–Al bricks while substituting magnesia–chrome bricks in the chromium-free campaign of refractory lining of RH degassers. Thanks to the prominent effect of the whisker bond, such a refr [...]

by Gilles R. G. Monif

Received: 06 January 2019;  Published: 04 June 2019;  doi: 10.21926/obm.hg.1902021

Using the therapeutic intervention points identified by the Hruska Postulate, the probability of curing Crohn’s disease through destroying the anti-MAP template is discussed.

by Koji Takahashi  , Tatsuo Kanda  , Yuki Haga  , Reina Sasaki  , Masato Nakamura  , Shuang Wu  , Shin Yasui  , Hidehiro Kamezaki  and Osamu Yokosuka

Received: 23 June 2017;  Published: 27 July 2017;  doi: 10.21926/obm.hg.1703004

(1) Background: Infection with hepatitis B virus (HBV) infection during pregnancy occasionally raises concerns, including acute exacerbation and the potential for mother-to-child transmission. (2) Case Report: Here, we present a case of a female patient with a chronic HBV infection who was treated with tenofovir disoproxil fumarate (TDF) and had a normal pregnancy and delivery. Furthermore, the use of TDF, HBV vaccination and passive immunization of her child with hyperimmune hepatitis B immunoglobulin successfully [...]

by Varrassi Giustino

Received: 01 February 2024;  Published: 02 February 2024;  doi: 10.21926/obm.neurobiol.2401210

Neurobiology is an expansive field of studies encompassing the nervous system's anatomical and physiological aspects [1]. This complex framework's deep study and understanding have facilitated a more intricate comprehension of the interconnections among various nervous system components implicated in pain perception, transmission, modulation, and adaptation.

by Nadia A. Abdelmegeed Abdelwahed  and Muhammad Sufyan Ramish

Received: 12 May 2024;  Published: 19 August 2024;  doi: 10.21926/obm.neurobiol.2403242

In the present era of digitalization, technology plays a prominent role in relaxation and brain development (BD), specifically for university students. The present study explores the impact of technology use and digital characteristics (DC) in developing students' BD. We applied the quantitative methods; the study collected 328 samples from Egypt's different public sector universities through a questionnaire. Using path analysis through analysis of moment structures (AMOS), the results demonstrate a positive effect [...]