Macroscopic Aspergillus Infection at the Anastomosis of a Lung Transplant Recipient
Abstract
1467 8370
Macroscopic Aspergillus Infection at the Anastomosis of a Lung Transplant RecipientAbstract
A 65-year-old female with a history of right lung transplantation (LTx) for chronic obstructive pulmonary disease (COPD) 9-years prior complicated by grade 3 bronchiolitis obliterans syndrome (BOS) was admitted to the hospital for chest pain and dyspnea on exertion (DOE). Her bronchoscopy revealed fluffy, endobronchial lesions that were adherent to the right sided anastomosis resulting in mild obstruction of the right mainstem bronchus. Pathology from biopsies of the endobronchial lesions revealed hyphal fungal org [...] 1467 8370 |
Dysphagia in the Older Age SettingAbstract
Dysphagia, or difficulty swallowing, is a common condition, especially among the elderly population and can become debilitating. As we age, there are subtle changes in esophageal motility, but by no means is dysphagia ever considered to be a normal result of aging. Dysphagia usually presents with a variety of accompanying symptoms ranging from regurgitation during meals, mild discomfort, to severe chest pain. It can be challenging to localize the dysphagia from the history. The underlying etiology may become eviden [...] 1977 18046 |
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Open Access Short Communication Lack of Effect of Human Chorionic Gonadotropin in Mixed Lymphocyte Reaction in XenotransplantationAbstract
It has been speculated that the immunomodulation associated with pregnancy, e.g., decreasing pro-inflammatory cytokines, increasing anti-inflammatory cytokines, upregulation of T regulatory cells (Tregs), is in part due to the effect of human chorionic gonadotropin (hCG). In this study, we tested the effect of hCG on proliferation of human peripheral blood mononuclear cells (PBMCs) stimulated by irradiated pig PBMCs. Mixed lymphocyte reaction (MLR) was carried out with human PBMCs as responders and irradiated wild- [...] 1693 8756 |
Design and Implementation of a Laboratory Sucker Rod Pumping Unit Using Industry 4.0 ConceptsAbstract
The Industry 4.0 is here, and advanced technologies are widely available for domains such oil and gas which are traditionally slow in adopting extreme new technologies. This paper presents the design architecture and implementation of effective data acquisition (DAQ) and monitoring system applied to an experimental sucker rod pumping unit for both event occurrence and educational purpose using latest technological advancements and industry 4.0 principles. The designed framework allows control and monitoring of anal [...] 2847 15255 |
Modeling Tile Drainage Outflow in Thin Agricultural Soils with Impermeable under Layer in Newfoundland and Labrador, Canadaby
Abstract
Subsurface tile drainage installation helps to maintain water table levels and to meet adequate crop moisture requirements. Artificial subsurface drainage continues to be a common practice in Newfoundland and Labrador (NL) and elsewhere around the world. The main objective of this study was to evaluate the performance of DRAINMOD in simulating water table depth (WTD) and water outflow from tile drained agricultural fields. This site on the Avalon Peninsula of Eastern Newfoundland has a rolling landscape with predom [...] 2141 12103 |
Numerical Investigation of Pyrotechnical Initiators and Their Impact in Airbag Inflator Applications: Ballistic Modeling and Functional AnalysisAbstract
A numerical model describing the ballistic behavior of a commercially used initiator is presented in this article. This model was built on the principle of conservation of mass and energy in the multi-phase framework incorporated with multi-loaded conditions. After obtaining the information about the grain size distribution in each composite, a fixing factor was proposed based on the surface area ratio of the composites. Thus, the solid propellant burning process based on distributed grain size was described, and t [...] 3175 17459 |
Cytomegalovirus in Lung TransplantAbstract
Lung transplantation is a therapeutic option for patients with advanced lung diseases. Lung transplant outcomes have improved over time with improvements in the management of these complex patients. Cytomegalovirus is a common opportunistic organism affecting all solid organ transplant recipients. Characteristics unique to lung transplantation can make this virus difficult to manage, with myriad complications including graft failure and death. Ongoing research into and understanding of cytomegalovirus has opened ex [...] 3474 19472 |
Influence of Aging, Sterilization, and Composition on the Degradation of Polyurethane Foamsby
Abstract
Shape memory polymers (SMPs) are highly attractive materials for medical devices. Specifically, SMP foams are currently being used as embolic devices in peripheral and cerebral vascular applications. To ensure the proper function and safety of these materials in their intended applications, it is important to understand how processing treatments, such as aging, sterilization, and foam composition can influence their degradation. Here, SMP foams were treated with industry relevant processing parameters, and the infl [...] 2251 13310 |
Automated Probabilistic Analysis and Parametric Modelling of the Seasonal-Diurnal Wind VectorAbstract
A refined and extended version of the Offset Elliptical Normal mixture model has been developed to parameterise the seasonal diurnal wind vector automatically. Automated using R scripts, the method eliminates any potential risk of confirmation bias posed by the manual supervision in the original method. Refinements to the method include the latest algorithms for clustering of Gaussian mixtures, with Bayesian regularisation to set the number of components and to limit the predisposition to overfit. A new extension u [...] 1649 9096 |
Psilocybin as a Novel Pharmacotherapy for Treatment-Refractory Anorexia NervosaAbstract
Anorexia Nervosa (AN) is a major health problem with one of the highest mortalities and treatment costs of any psychiatric condition. Cognitive behavioural therapy (CBT) is currently the most widely used treatment for AN in adults but provides remission rates ≤ 50%. Treatment drop-out is exceedingly high and those that persevere with treatment often relapse, causing increased risk of morbidity and mortality. There is an urgent need to find new interventions, especially as there are no approved pharmacological treat [...] 3540 32405 |
Dynamic Behavior of Li in Solid-State Li-Ion Batteries Studied using MeV Ion Beam Analysis Techniquesby
Abstract
In this review, various studies on the Li depth profiles of metal/electrolyte/metal capacitors and batteries of Au/LCO/LATP/Pt, LCO/LiPON/Si, and LMO/LiPON/NbO with different metal electrodes at both sides (by bias; LCO =LiCoO2, LATP =Li3.1Al0.86Ti1.14Ge1.27P1.73O12, LMO =LiMn2O4, NbO = Nb2O5) using the in-situ reflection ERD (ERD) technique with 9MeV O+4 ion beam and transmission ERD (TERD) technique with 5MeV He+2 ion beam, respectively, are described. For capacitors, the transport fraction of Li-ion in the elect [...] 1839 9582 |
Development of Wind IPMSG Based Bipolar DC MicrogridsAbstract
This paper presents the development of a wind Interior Permanent-Magnet Synchronous Generator (IPMSG) based bipolar DC microgrids along with various switch-mode rectifiers. Firstly, the wind IPMSG is established and adequately controlled to possess satisfactory generating characteristics during different driven speeds and loads. Later, the boost switch-mode rectifier (SMR) based bipolar DC bus is established. Further, three-phase single-switch (3P1SW) boost SMR, three-phase two-switch (3P2SW) three-level boost SMR, [...] 1743 9810 |
Use of α-Lactalbumin [α-La] from Whey as a Vehicle for Bioactive Compounds in Food Technology and Pharmaceutics: A ReviewAbstract
Whey protein is a byproduct of cheese, casein, and Greek yogurt produced in Europe, North America, and Australasia. It is a substantial source of functional proteins and peptides for the worldwide food industry. α-Lactalbumin (α-La) is a globular protein that can be isolated from WPI (whey protein isolates) using techniques such as chromatography/gel filtration, membrane separation, etc. α-La is used in the elaboration of functional foods and is a very good source of peptides with anticancer, antimicrobial, antivir [...] 2077 13660 |
Varicella-Zoster Gastritis in a Liver Transplant Patient: A Call to Attentionby
Abstract
The reactivation of the Varicella-zoster virus (VZV) is a rare cause of acute gastritis in adults. About 30 cases have been reported in the literature, mostly with immunocompromised patients and mainly after bone marrow transplantation or during the development of malignant hematological diseases. Clinically, it is usually accompanied by cutaneous manifestations. Here, we studied a case of VZV gastritis in a liver transplant (LT) patient. We described the main symptoms, endoscopic findings, histologic changes, and [...] 1192 5681 |
A Review of the Multi-Physical Characteristics of Plant Aggregates and Their Effects on the Properties of Plant-Based ConcreteAbstract
The use of plant aggregates obtained from agricultural co-products mixed with mineral binders to form eco-friendly insulating building materials has been initiated for a few years to bring environmentally friendly solutions to the construction sector. Several studies on different agro-resources have already been carried out, providing various information about the properties of plant aggregates and plant-based concrete. However, the characteristics of the agricultural co-product, which allow it to qualify as a plan [...] 2614 21802 |
Potential Impact of UWWT Effluent Discharges on Ruditapes decussatus: An Approach Using BiomarkersAbstract
The use of biomarkers in bivalves has gained significance as a reliable method for the assessment of the presence and effect of contaminants in aquatic ecosystems. However, it is important to note that the biomarkers respond not only to contaminant loadings and bioavailability but also to environmental stress. Therefore, the association between biomarkers and contamination/pollution should be conducted cautiously as the environmental factors also affect their response. These factors should be integrated into the as [...] 1445 10058 |
Estimating Met-Ocean Parameters during a Tropical Cyclone for Marine Science and Engineeringby
Abstract
During a tropical cyclone (TC) worldwide, the Regional and Mesoscale Meteorological Branch (RAMMB) of NOAA/NESDIS (http://rammb.cira.colostate.edu/) issues real-time TC surface wind analyses. The purpose of this article is to provide value-added estimations of several meteorological and oceanographic (met-ocean) parameters including overwater friction velocity and turbulence intensity, variation of the wind speed with height, significant wave height, peak or dominant wave period, wind-driven currents and wind-stres [...] 2073 11319 |
Establishing and Evaluating a Multidisciplinary Community-Based Sleep Clinic for Children with Neurodevelopmental Difficulties in Inner LondonAbstract
We describe our experience of setting up and evaluating a community-based multi-disciplinary sleep service for children with neurodevelopmental disorders and psychosocial vulnerabilities.Referrals are accepted for children (1-18 years of age) with persistent sleep problems, and neurodevelopmental difficulties or significant psychosocial adversity, living in two inner-city boroughs.Holistic sleep assessment involves 1-hour Paediatrician-led consultation, often followed by Psychologist-led parent workshop, with follo [...] 1665 9558 |
The PBAR Protocol: Antipsychotic Medication Reduction in the Nursing HomeAbstract
Neuropsychiatric symptoms (NPS) occur in almost all persons living with dementia. Antipsychotic medications are often prescribed inappropriately for persons living with dementia who experience NPS. Adverse side effects of antipsychotic medications include falls, sedation, cognitive dysfunction, prolonged QTc interval, extrapyramidal side effects, cerebrovascular events, metabolic changes, infection, and mortality. The purpose of this descriptive quality improvement project was to test the feasibility and preliminar [...] 1794 326153 |
The Use of Sulfur Waste to Protect Against Corrosion of Metal ImplantsAbstract
Metal parts of endoprosthesis have a detrimental effect on the bones that come into contact with them and on the entire body of the patient. Coating them with biocompatible layers (hydroxyapatite and bioglass) has not yet brought about permanent results. In this study, the author showed the possibility of using a binder containing sulfur waste for this purpose. The sulfur binder is used industrially in electrical engineering and construction applications. The chemical properties of elemental sulfur indicate that it [...] 1819 9061 |
Performance Investigation of a Nickel Cermet Anode Modified with Copper, Alkaline Earth Metal Oxide, Boron, and Perovskite for Direct Methane Fuel CellAbstract
The metallic copper, alkaline earth metal oxide, boron, and perovskite were incorporated on the surface of a Ni-cermet anode, and the performance of the modified Solid Oxide Fuel Cell (SOFC) anode was evaluated. The cell performance was analyzed by voltage-current characteristics (V-I curve) and H2-CH4 step reactions (P-t curve) in a potentiostatic mode. Besides, we also determined if a metallic phase or high electronic conductivity of the anode is important for a cell to perform well when H2 is used as a fuel, whe [...] 2185 12301 |
Modelling the Cumulative Number of COVID-19 CasesAbstract
Each country has its own characteristics of COVID-19 infection trajectory and epidemic waves. Differences in government-implemented restrictions and social regulations result in variability of the virus transmissions and spread dynamics. This in turn results in various shapes of the growth function used to represent and describe the propagation of infection. Statistical methods are applied to fit non-linear functions to represent daily time-series data of the cumulative numbers of COVID-19 cases. The aim of this wo [...] 2190 12478 |
Effects of Oxygen on Renal Function and Oxidative Stress During Hypothermic Machine Perfusion in an Experimental Porcine Model of Kidney Donation after Cardiac Deathby
Abstract
The efficacy and safety of using high concentrations of oxygen during hypothermic machine perfusion (HMP) have not been fully elucidated to date. This study investigated the impact of administering high concentrations of oxygen on renal function during HMP in a porcine donation after circulatory death (DCD), as well as the metabolic and biochemical effects of this method. A randomized nonblinded cohort study was established in a porcine transplant (KT) model mimicking Maastricht type III DCD under oxygen-supplement [...] 1560 9946 |
An Ab Initio Study of Li/Ni-doped NaxMeO2 Cathode Material for Na-Ion Batteriesby
Abstract
The current state-of-the-art quantum mechanics methodologies were applied to derive information on the bulk and surface properties of the P2-type layered oxide Na0.85Li0.17Ni0.21Mn0.64O2 (NLNMO), a cathode material. The special quasi-random structure (SQS) approach was employed to identify the arrangement of Li, Ni, and Mn ions in a supercell containing 115 atoms. Both the cell parameters and atomic positions were determined from DFT-PBE+U calculations to highlight specific distortions induced by the dopants (Ni an [...] 2154 11615 |
The Trails Making Test. Does a Single Trial Reflect Performance Capability?Abstract
Information processing speed (Reaction time, RT) to a single administration of the Trails A and Trails B components of the Trail Making Test (TMT) is used in the assessment of brain and behavioural functional integrity across the lifespan in both clinical and research contexts. Although the clinical utility of such single trial-related and thus rapidly gained results, is recognised, it is possible that its administration as a single trial only, precludes its ability to provide a more in-depth and thus relevant repr [...] 2246 32195 |
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