by R. Paul Robertson

Received: 13 February 2023;  Published: 17 May 2023;  doi: 10.21926/obm.transplant.2302184

Pancreatic islet transplantation (ITx) has moved from the experimental phase of development to a position of an accepted and appropriate procedure to apply in clinical medicine. The primary indication for use of ITx is for management of dangerous and recurrent hypoglycemia secondary to use of exogenous insulin for management of hyperglycemia in people with type 1 diabetes. ITx involves procurement of a pancreas donated by a person who has died. The organ is taken to a specialized laboratory for isolation of islets [...]

by Debora Di Jorio

Received: 14 April 2020;  Published: 22 June 2020;  doi: 10.21926/obm.neurobiol.2002063

The story of each individual is essentially the story of their learning processes and relationships from the moment they were born. Indeed, the story of learning processes is merely a constant stratification of experiences based on biological and neurofunctional features that are influenced by genetic and cultural factors and subject to environmental stimuli constantly reshaping their behaviour.Neuroscientific studies conducted over the past decades have highlighted a unique feature of the human nervous system, cal [...]

by Caroline Soares  and Paula Ministro

Received: 04 January 2024;  Published: 19 March 2024;  doi: 10.21926/rpn.2401003

Inflammatory bowel diseases (IBD) affect primarily the bowel, but they are multisystemic diseases with a wide range of extraintestinal manifestations and complications. Nutritional imbalance occurs frequently in patients with IBD. The spectrum of malnutrition goes from undernutrition (low protein-caloric intake, disease-related malnutrition, micronutrient deficiencies) to overnutrition and obesity. The nutritional status of patients with IBD is increasingly recognized as a key aspect of the treatment and must be ad [...]

by Fengxia Liang  , Qi Huang  , Rui Chen  , Song Wu  , Gary Lu  , Jianmin Liu  , Jia Li  , Lu Wang  , Hua Wang  and Gerhard Litscher

Received: 19 February 2017;  Published: 08 May 2017;  doi: 10.21926/obm.icm.1702002

Qigong is a form of traditional Chinese exercise combining breathing, movement, and meditation to improve fitness for the purpose of preventing disease and prolonging life. We review the clinical efficacy and underlying mechanism of the application of Qigong in the healthcare setting. In addition, we discuss topics such as the impacts on respiratory, cardiovascular function, and immune function, as well as studies of the influences on brain function and mental health. In summary, there is strong evidence of the cli [...]

by Jenny Berrío  , Weiwen Wang  and Bart A. Ellenbroek

Received: 22 February 2019;  Published: 14 March 2017;  doi: 10.21926/obm.neurobiol.1701001

Antipsychotics have been a pillar in the treatment of schizophrenia since their introduction more than 60 years ago. Their variety in structures and receptor binding properties confers on them a complex clinical profile of effectiveness and risk of adverse side-effects. Although antipsychotics are best known for their therapeutic effects in schizophrenia, these are limited to the positive symptoms, with much less influence on negative symptoms or cognitive deficits. Moreover, although the newer (so-called second-ge [...]

by Lei Zhang  , Xian-Zhang Hu  , Xiaoxia Li  , Jacob Dohl  , Tianzheng Yu  and Robert J. Ursano

Received: 28 December 2018;  Published: 21 March 2019;  doi: 10.21926/obm.geriatr.1901041

Depression, PTSD, and hostility are common mental conditions that are associated with aging. A growing body of research has highlighted the possible effects of depression, PTSD, and hostility on aging and telomere length (TL), a cellular aging marker. Individuals who exhibit excessive responses to stressors show notable circulating inflammatory responses with high cortisol reactivity, which increases cell turnover and oxidative stress and may subsequently contribute to shortened TL. This review focuses on the most [...]

by Kristin Drexler  and Ed Boles

Received: 02 March 2024;  Published: 25 July 2024;  doi: 10.21926/aeer.2403017

Watershed health and integrity are essential to human and ecosystem health and well-being. New River watershed communities in northern Belize, Central America are vulnerable to annual ‘cultural eutrophication’ - natural eutrophication exacerbated by human activity. Human-caused pollution from agriculture, septic effluent, and industrial drainage, in combination with extended drought and the slow flow of New River, has caused more frequent and prolonged periods of eutrophication. In this qualitative study, 42 New Ri [...]

by Antonella Sansone  , Peta Stapleton  , Alan Patching  and Zoe Lawrence

Received: 06 July 2023;  Published: 02 January 2024;  doi: 10.21926/obm.icm.2401001

This feasibility study sought to investigate the impact of an online 9-session Prenatal Mindfulness Relationship-Based (PMRB) group treatment program upon maternal mental health (depression, anxiety, and stress), interoception, and mother-infant relationship during pregnancy and post-partum. The study was designed in two parts 1) a quantitative examination of pre, post-treatment and 10-12 weeks post-partum measures targeting 13 pregnant women from a non-clinical population and 2) a qualitative exploration of the sa [...]

by Yan Yang  , Gerhard Litscher  , Zemin Sheng  and Lu Wang

Received: 12 February 2020;  Published: 20 March 2020;  doi: 10.21926/obm.icm.2001015

Pain could be directly related to autonomous imbalance. To date, only one scientific work examining heart rate variability (HRV) and heart rate (HR) as the important parameters of autonomous nervous system (ANS) in the context of clinical routine acupuncture treatments for lumbosacral pain conditions is available in the listed databases. The present study aimed to investigate the short-term effects of HRV and HR, during and after the acupuncture needle stimulation in patients with lower back pain. Eighteen patients [...]

by Neil E Clapton  and Syd Hiskey

Received: 31 July 2022;  Published: 04 January 2023;  doi: 10.21926/obm.icm.2301001

Traditional Martial Arts practice(s) can be construed as forms of fully embodied Compassionate Mind Training (CMT). Integration of these body-mind systems can be a powerful means to cultivate and entrain important therapist competencies in compassionate engagement and action. Through such training and personal practice, compassion-focused therapists can develop and enhance their abilities to stimulate and access compassionate motivation at a deeply embodied level. Martial arts-informed CMT thus has the potential to [...]