by Jignesh P. Sathvara  and Rajendrasinh N. Jadeja

Received: 12 February 2026;  Published: 30 April 2026;  doi: 10.21926/rpse.2602007

A new series of bis-quadridentate ligands (L1-L3) and their corresponding zinc(II) complexes (Complex 1-3) were rationally designed, synthesized, and characterized. The ligand framework features multiple donor sites that enable stable coordination to zinc(II), yielding well-defined metal complexes. The structures of the synthesized compounds were confirmed using a combination of analytical and spectroscopic techniques. Thermal gravimetric analysis revealed that all zinc complexes exhibit exceptional thermal stabili [...]

by Alžbeta Jauschová  , Jana Žiarovská  and Lenka Kučerová

Received: 26 December 2025;  Published: 23 March 2026;  doi: 10.21926/obm.genet.2601331

Genetically conditioned variation in pollen has been demonstrated to have a substantial influence on reproductive mechanisms and population dynamics. The present study evaluated the genetic variability of 28 pollen samples of Corylus avellana L. using iPBS (Inter Primer Binding Sites Polymorphism) markers 1882 and 2152. The collection of biological material was undertaken at various locations across five European countries, with the objective of capturing a broad spectrum of environmental conditions. The genetic re [...]

by Thu-Thao Thi Huynh  , Thi Nga Nguyen  , Anh-Duy Hoang Nguyen  and Minh Trong Quang

Received: 15 January 2026;  Published: 07 April 2026;  doi: 10.21926/obm.genet.2602334

Rauvolfia tetraphylla L. (1753) is an important medicinal species of Apocynaceae, widely used for its rich indole alkaloids and related bioactive compounds. We report the first complete chloroplast genome of R. tetraphylla. The genome exhibits a typical circular quadripartite structure of 155,667 bp, with an overall GC content of 37.8%. The genome comprises a large single-copy (LSC) region of 86,332 bp, a small single-copy (SSC) region of 17,853 bp, and a pair of inverted repeat (IR) regions of 25,741 bp each. A to [...]

by Noora A. Hadi  , Rehab S. Ramadhan  , Khalid Suhail A. AlAzzawi  , Rebah N. Algafari  , Sura S. Talib  and Rawaa A. Khalaf

Received: 06 December 2025;  Published: 15 March 2026;  doi: 10.21926/obm.genet.2601328

Diabetes mellitus (DM) is widely spread among populations. About 3 of 10 people show the symptoms of this disease. Many factors may cause this illness in both types (type 1 and type 2 DM), mainly attributed to insufficient insulin production in type 1 DM or developing insulin resistance in type 2 DM. Genes that control specific biochemical pathways involving glucose metabolism can interfere with the manifestation of this disease when they undergo genetic changes like KRAS. Investigating the role of KRAS in DM. Abou [...]

by Lyubov Starodub  , Nataliia Mokhnachova  and Ostap Zhukorskyi

Received: 01 December 2025;  Published: 01 April 2026;  doi: 10.21926/obm.genet.2602333

The article reveals the variability of the genome of cattle of the local small-numbered domestic Brown Carpathian breed using cytogenetic and molecular genetic polylocus markers, and justifies the need to integrate local breeds into the modern system of agricultural production in accordance with FAO requirements. The work aimed to study the genetic uniqueness of cows of the brown Carpathian breed using cytogenetic and molecular genetic markers. The karyotype of the animals corresponded to the species norm and was 2 [...]

by Nisa Ayu Thayalisha Hadi  , Agustini Utari  , Nydia Rena Benita Sihombing  , Tri Indah Winarni  and Nani Maharani

Received: 08 January 2026;  Published: 06 May 2026;  doi: 10.21926/obm.genet.2602338

Noonan syndrome (NS) is an autosomal dominant disorder with a wide spectrum of symptoms and clinical phenotypes, including short stature, congenital heart defects (CHD), and distinctive facial features. A pathogenic variant in the PTPN11 gene is the major cause of NS. This is a preliminary study in Indonesia involving 29 patients with clinical features of NS. Detailed clinical and echocardiography data were collected. Genomic DNA was extracted from a peripheral blood sample. Exome sequencing or PCR followed by Sang [...]

by Aster Woldu Gebrearegay  , Melaku Tesfaye  and Alemu Gizaw

Received: 04 January 2026;  Published: 24 April 2026;  doi: 10.21926/aeer.2602007

Hexavalent chromium (Cr(VI)) is a carcinogenic pollutant commonly found in wastewater from tanning and electroplating industries. This study investigates the efficiency of raw Cordia africana sawdust as a biosorbent for Cr(VI) removal. Batch adsorption experiments were conducted by varying pH (3-8), contact time (10-120 min), and Cr(VI) concentration (21-47 mg/L) using Response Surface Methodology (RSM) with Box-Behnken design. Characterization was performed using FTIR, SEM, BET, pH, and PZC analysis before and aft [...]

by William Winlow  and Andrew Simon Johnson

Received: 04 August 2025;  Published: 13 April 2026;  doi: 10.21926/obm.neurobiol.2602331

Comprehending the nature of nerve communication is fundamental to our understanding of the functioning of nervous systems in general. The ionic mechanisms underlying action potentials in the squid giant axon were first described by Hodgkin and Huxley in 1952, and their findings have formed our orthodox view of how the physiological action potential functions. However, substantial evidence has now accumulated to show that the action potential is accompanied by a synchronized coupled soliton pressure pulse in the cel [...]

by Elham Alimoradi  , Parham Nejati  , Fatemeh Molavi  , Setareh Isaee  , Soudeh Ghafouri-Fard  and Reza Alibakhshi

Received: 25 November 2025;  Published: 13 April 2026;  doi: 10.21926/obm.genet.2602336

Sensorineural hearing loss (SNHL) describes a diverse group of clinically and genetically distinct disorders of the auditory system. SNHL is associated with mutations in up to 150 genes. Among them is Cadherin 23 (CDH23), which is associated with both Usher syndrome and non-syndromic hearing loss. In the current study, we used WES to find the genetic cause of SNHL in an extended Iranian family. WES and subsequent Sanger sequencing confirmed the occurrence of a novel homozygote variant in the CDH23 gene (c.817T>C, p [...]

by Anastasiia Kornutii  , Oleksandr Kornutii  , Ivanna Shymanska  , Maiia Bondarenko  and Natalia Prokopchuk

Received: 12 September 2025;  Published: 13 April 2026;  doi: 10.21926/obm.genet.2602335

Craniosynostosis is a disorder characterized by premature closure of cranial sutures, resulting in restricted skull growth perpendicular to the affected suture and compensatory growth in other directions. Over 180 syndromes have been classified under craniosynostosis, of which eight are associated with mutations in the fibroblast growth factor receptor 2 (FGFR2) gene: isolated coronal synostosis, Pfeiffer syndrome, Crouzon syndrome, Apert syndrome, Beare–Stevens syndrome, Jackson–Weiss syndrome, Crouzon syndrome wi [...]