An Interview with Dr. Blanca Hernandez-Ledesma
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Machine Perfusion in DCD Lung Transplantation: Advances in Preservation and Donor Pool Expansionby
Abstract
To address the pressing shortage of donor lungs, Donation after Circulatory Death (DCD) transplantation has become a vital strategy for expanding the donor pool. Minimizing warm ischemic injury is crucial for optimizing organ viability and function. This review synthesizes current evidence on Normothermic Regional Perfusion (NRP) and Ex-Vivo Lung Perfusion (EVLP) in DCD lung transplantation. Analysis reveals their growing efficacy in minimizing ischemic damage, facilitating organ assessment, and expanding the trans [...] 451 1584 |
Selenium Supplementation in Rheumatoid Arthritis: Evidence from Controlled Clinical Trials and Mechanistic InsightsAbstract
Selenium (Se) is a key micronutrient integrated into selenoproteins such as glutathione peroxidases (GPx), which are responsible for crucial antioxidant and anti-inflammatory mechanisms. Oxidative stress contributes to the immunopathogenesis and chronic joint damage of rheumatoid arthritis (RA), supporting interest in selenium supplementation as an adjunct therapeutic strategy. This review was based on a structured literature search of major biomedical databases and evaluated six controlled clinical trials involvin [...] 704 1583 |
Correlation between the Storage Pattern of Spent Fuel Casks and the Neutron Multiplication FactorAbstract
The effective neutron multiplication factor (keff) of a fissile system is a function of space and time f(x, y, z, t), where (x, y, z) are the coordinates of the reference point in space, and t is time. The evidence of the time-dependence of the neutron multiplication factor of a fissile system was published in 2017. The spatial dependence is as important as the time dependence, as interacting arrays of fissile material during storage can lead to an increase in the system (keff). Therefore, evaluation of how the sto [...] 417 1554 |
Preparation and Properties of Frozen Yoghurt Made from Camel Milk Fortified with Dates and Banana FruitsAbstract
This study was conducted to process frozen yoghurt (FY) from camel milk (CM) flavored with either 5% or 8% banana (B) or dates (D). The mix of FY consists of stirred yoghurt, sugar, Gum Arabic, and banana (Musa lutea) or dates (Phoenix dactylifera). The mix was divided into 4 portions and then each mix was sub-derived into an ice-cream machine and then packed into plastic cups that were stored at -18°C for 5 weeks. The chemical composition and sensory evaluation were conducted weekly. The chemical composition of FY [...] 524 1540 |
Red Meat Consumption and Rheumatic Diseases: A Comprehensive Narrative ReviewAbstract
Dietary factors influence chronic inflammation and immune regulation, potentially affecting the onset and activity of rheumatic disease. Red meat, a major source of protein, heme iron, and saturated fat, has been linked to metabolic and inflammatory disorders, yet its role in rheumatic diseases remains unclear. To comprehensively evaluate the relationship between red-meat consumption and major rheumatic diseases—including rheumatoid arthritis (RA), gout, systemic lupus erythematosus (SLE), and other inflammatory or [...] 660 1533 |
Wind Turbine Tower Structural and Cost Optimisation within Acceptable Structural Integrityby
Abstract
As the demand for cleaner-greener energy surges owing to more nations adopting Net Zero Emission by 2050, wind turbine (WT) technology is increasingly poised as one of the technologies to match the demand. Capacity building in the development of cost-effective WT tower with improved reliability and safety has become critical to delivering Net Zero mandate. This research demonstrates implementation of Taguchi Design of Experiment (DoE) in conjunction with Signal-to-noise ratio (S/N) to optimise both structural desig [...] 445 1498 |
Compassionate Mind Training for All: An Evaluation of a One-Day Compassionate Mind Training Workshop for Mental Health NHS Staff as Part of Compassion Focused Staff SupportAbstract
It has become increasingly evident that individuals who work in the NHS can be heavily impacted by the nature of their work; for instance, PTSD, work related burnout, vicarious trauma, moral injury, anxiety, and depression. In turn, individuals who experience said psychological difficulties often require work-related mental health leave from work. This paper examines the experience of a One-day Compassionate Mind Training workshop (CMT), available for all NHS staff. This day has an emphasis on developing multidirec [...] 439 1497 |
Diagnostic Challenges of Rothmund-Thomson Syndrome in Infancy: A Case Report from a Resource-Limited Settingby
Abstract
Rothmund-Thomson syndrome (RTS) is a rare autosomal recessive disorder characterized by early-onset poikiloderma and multisystem abnormalities. Diagnosis is often confirmed through genetic testing, but in many resource-limited settings, molecular studies are unavailable, necessitating reliance on clinical and histopathological evaluation. We report a 1-year-old boy referred for assessment of progressive pigmented skin lesions. The patient was referred by a pediatrician with febrile neutropenia, bicytopenia suspicio [...] 523 1493 |
Psychological Flexibility in Borderline Personality Disorder: A Comparative Study with Healthy ControlsAbstract
This study aimed to examine the psychological flexibility of individuals diagnosed with borderline personality disorder (BPD) compared to healthy controls. Psychological flexibility is a key construct related to mental health and adaptive functioning, and understanding its levels in BPD can provide insight into symptom severity and treatment outcomes. The study included 58 individuals diagnosed with BPD and 62 healthy volunteer controls, all meeting specific inclusion and exclusion criteria. Participants completed [...] 393 1457 |
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