Linking Brain, Hormones, and Metabolism: Pathophysiology and Treatment of Antipsychotic-Induced Cardiometabolic Side Effects
Abstract
847 2576
Linking Brain, Hormones, and Metabolism: Pathophysiology and Treatment of Antipsychotic-Induced Cardiometabolic Side Effectsby
Abstract
This narrative review explores the pathophysiological consequences, neuroendocrine processes, and treatment approaches aimed at reducing the cardiometabolic adverse effects linked to antipsychotic medications; in particular, it highlights recent mechanistic advances in receptor-mediated metabolic dysregulation and emerging therapeutic implications. Schizophrenia, which is a long-term and debilitating disorder, correlates with a substantially shorter life expectancy (15-20 years less than that of the general populac [...] 847 2576 |
Administration of the Effects of Wireless Electromagnetic Fields on Living Tissues in Sustainable Urban Ecosystemsby
Abstract
A relevant objective of managing an electromagnetic (EM) device is to improve its expected results and reduce its undesirable side effects. In this context, this paper aims to evaluate the interest of the two One Health and Responsible Attitude methods in the daily practice of wireless transmission (or transfer) in EM energy devices. These approaches are respectively linked to device eco-design and optimization, as well as to the protection of biodiversity and ecosystems against device side effects related to EM fi [...] 817 2573 |
Advancing Marine Renewable Energy for Island Nations: Design and Development of a 20 kW Floating Kuroshio Turbine (FKT)Abstract
Taiwan relies heavily on imported fossil fuels, with over 98% of its energy demand supplied by foreign sources, posing significant challenges to national energy security. To explore alternatives, this study investigates the potential of marine renewable energy by developing a 20 kW floating hydrokinetic turbine prototype designed for deployment in the Kuroshio Current. The research encompasses system design, model validation, and both tank and at-sea testing to evaluate hydrodynamic performance and power generation [...] 784 2565 |
Preparation and Properties of Frozen Yoghurt Made from Camel Milk Fortified with Dates and Banana FruitsAbstract
This study was conducted to process frozen yoghurt (FY) from camel milk (CM) flavored with either 5% or 8% banana (B) or dates (D). The mix of FY consists of stirred yoghurt, sugar, Gum Arabic, and banana (Musa lutea) or dates (Phoenix dactylifera). The mix was divided into 4 portions and then each mix was sub-derived into an ice-cream machine and then packed into plastic cups that were stored at -18°C for 5 weeks. The chemical composition and sensory evaluation were conducted weekly. The chemical composition of FY [...] 874 2556 |
Framework for the Secured Integration of Renewable Energy into Power SystemsAbstract
This research introduces a blockchain framework to improve security and transparency for the use of renewable energy in power systems. The framework utilizes a permissioned blockchain architecture and IoT-based real-time monitoring to ensure data integrity and confidentiality and support efficient peer-to-peer (P2P) energy trading. Compared with traditional centralized energy management systems, the proposed design increases transaction security by 35%, decreases verification wait times by 28%, and decreases the ri [...] 772 2551 |
Rapid Green Synthesis of Silver Nanoparticles and Alginate-Silver Nanocomposite Beads Using Mashmoom (Ocimum basilicum), a Bahraini Household Medicinal HerbAbstract
The study focuses on the rapid green synthesis of silver nanoparticles (AgNPs) and alginate-silver nanocomposite (Alg-AgNc) beads using sweet basil or Mashmoom (Ocimum basilicum), a common household medicinal herb in Bahrain. The aqueous extract of mashmoom was used as a reducing and stabilizing agent in the reduction of the precursor salt, silver nitrate, and formation of stable AgNPs. The Alg-AgNc beads were prepared by ionotropic gelation of sodium alginate-AgNPs solution in calcium chloride. A strong surface pl [...] 728 2528 |
Optimizing Donor Management Strategies for DCD Lung Procurementby
Abstract
Donation after circulatory death (DCD) offers a vital strategy to expand the donor lung pool; however, DCD lungs are uniquely susceptible to warm ischemic injury during procurement. This chapter reviews evidence-based and emerging donor management strategies aimed at mitigating ischemic damage and optimizing the suitability of DCD lungs for transplantation, encompassing hemodynamic and ventilatory optimization, bronchoscopic clearance, targeted pharmacological interventions, and strategies to minimize transfusion r [...] 697 2526 |
Characterization of Drought Severity Using GRACE and TerraClimate Dataset in the Rift Valley Basin, EthiopiaAbstract
Characterizing drought severity using GRACE and TerraClimate datasets is globally important because it enables consistent, large-scale monitoring of both surface and subsurface water availability across data-scarce regions. This integrated perspective supports improved drought assessment, climate change impact analysis, and informed water-resource management worldwide. The Ethiopian Rift Valley has experienced recurrent hydrological drought hazards, posing serious threats to water availability, agricultural product [...] 839 2515 |
The Relationship between Hereditary Predisposition and Epigenetic Mechanisms of Schizophrenia DevelopmentAbstract
Schizophrenia is a multifactorial mental disorder associated with multiple SNPs in the human genome, located mainly outside the annotated protein-coding genes. These regions contain a large number of retroelements, which drive epigenetic regulation. Therefore, it is suggested that schizophrenia-associated SNPs exert their influence on the pathological functioning and activation of retroelements, which contribute to epigenetic imbalance in the brain with the development of pathological processes. A reflection of the [...] 752 2502 |
Differential Expression of MiR-21 and MiR-19 in Biliary Atresia: Diagnostic Potential and Therapeutic Implicationsby
Abstract
Biliary atresia (BA), a severe pediatric liver disease of unknown etiology, causes neonatal jaundice, progressive cholestasis, and life-threatening liver fibrosis. Emerging evidence suggests microRNAs (miRNAs) – small non-coding RNAs that regulate gene expression by binding target mRNAs may play a role in BA pathogenesis. Circulating miRNAs have shown diagnostic potential for various diseases, prompting our investigation of miR-21 and miR-19 as potential biomarkers in BA. We conducted a case-control study comparing [...] 823 2417 |
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