Pharmacological Strategies to Enhance Bone Graft Integration: Emerging Agents and Molecular Pathways
Abstract
1342 3005
Pharmacological Strategies to Enhance Bone Graft Integration: Emerging Agents and Molecular PathwaysAbstract
Bone grafting remains a cornerstone technique in orthopedic and reconstructive surgery, yet achieving successful graft integration continues to pose significant challenges, particularly in conditions such as osteoporosis, diabetes mellitus, and large bone defects. Traditional graft materials such as autografts, allografts, xenografts, and synthetics, often encounter limitations including immune rejection, poor vascularization, and insufficient osteogenic support. Emerging pharmacological strategies have shown promi [...] 1342 3005 |
Acknowledgment to Reviewers of Advances in Environmental and Engineering Research in 2024Abstract
The editors of Advances in Environmental and Engineering Research would like to express their sincere gratitude to the following reviewers for assessing manuscripts in 2024. We greatly appreciate the contribution of expert reviewers, which is crucial to the journal's editorial process. We aim to recognize reviewer contributions through several mechanisms, of which the annual publication of reviewer names is one. Reviewers can download a certificate of recognition directly from our submission system. Additionally, r [...] 543 2982 |
Maladjustment in Minority Youth from Community Network Disparities in the COVID-19 Lockdown Environmentby
Abstract
Pandemic lockdown orders resulted in closures to critical community networks. One such infrastructure was community recreation centers/parks. This infrastructure serves a critical role in building psychosocial wellness for youth. Socioeconomic minority youth face baseline disparity in center/park distribution and services. Youth recreation activity declined 50% as result of lockdown orders with corresponding decline in youth mental health status. Despite overall youth activity decline, White and high socioeconomic [...] 556 2957 |
Fabrication of CuO-Decorated Fe2O3 Nanoparticles as Efficient and Durable Electrocatalyst for Oxygen Evolution Reactionby
Abstract
The electrochemical water oxidation application of CuO@Fe2O3 materials as potential catalysts is being reported for the first time. A series of CuO@Fe2O3 with different molar ratios of CuO (5, 7, 10, 12, and 15%) was fabricated through precipitation followed by the impregnation method. Structural and electrochemical studies were carried out by using different analytical platforms, including X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FTIR), scanning electron microscopy (SEM), Energy dispersive [...] 923 2883 |
Nursing Care for a Patient with a Risk of Suicide Due to Depression Using the Solution-Focused Brief Therapy Approach: Case StudyAbstract
Adolescent depression is linked to suicidal ideation and attempts. Nurses are well-positioned to deliver brief, supportive interventions. Solution-Focused Brief Therapy (SFBT) emphasizes solutions and the activation of personal resources. To describe the feasibility and clinical utility of SFBT, delivered alongside pharmacotherapy, for reducing suicide risk in an adolescent with depression. Single-case report using a nursing process approach in a 17-year-old female inpatient with a major depressive episode and high [...] 472 2863 |
Deep Learning Approaches for Predicting Strain Energy in Heterogeneous MaterialsAbstract
This paper investigates data-driven strain energy prediction for heterogeneous elastic materials using the Mechanical MNIST benchmark dataset (60,000 28 × 28 stiffness maps by precomputed finite-element results). The results by classical regression models (linear regression, random forest, and gradient boosting) using hand-crafted features were compared with the results by the deep learning models (Convolutional neural network (CNN) and residual network (ResNet)) trained end-to-end on images. In held-out tests, CNN [...] 755 2782 |
Acknowledgment to Reviewers of OBM Genetics in 2024Abstract
The editors of OBM Genetics would like to express their sincere gratitude to the following reviewers for assessing manuscripts in 2024. We greatly appreciate the contribution of expert reviewers, which is crucial to the journal's editorial process. We aim to recognize reviewer contributions through several mechanisms, of which the annual publication of reviewer names is one. Reviewers can download a certificate of recognition directly from our submission system. Additionally, reviewers can sign up to the Web of Sci [...] 623 2779 |
Network Topology Similarities Across Cancer Types: Identifying Central Protein Hubs for Drug Discoveryby
Abstract
A molecular-level understanding of cancer is essential for the development of effective therapies. Constructing protein-protein interaction (PPI) networks offers a valuable approach to identifying dysregulated driver genes and potential therapeutic targets. In this study, we modeled cancer PPI networks as metric spaces and applied mathematical and computational algorithms to analyze their structural and functional properties. Our findings reveal that these networks share a conserved architecture across different ca [...] 663 2713 |
Evaluation of the Transitional Pain Service Specialized Iyengar-Informed Yoga Program for Chronic Post-Surgical Pain: A Pilot Randomized Controlled Trialby
Abstract
The objective of this randomized controlled trial (RCT) was to evaluate the feasibility and efficacy of a specialized Iyengar-informed yoga intervention for individuals who experience chronic post-surgical pain (CPSP). This prospective, multi-wave pilot RCT was pre-registered at clinicaltrials.gov (NCT03460028) and designed in accordance with the 2010 CONSORT statement. Participants (N = 21) with CPSP were out-patients or community members affiliated with a Toronto hospital. Participants were randomized to an 8-wee [...] 709 2699 |
TOP