by Edward F. Coyle

Received: 20 February 2025;  Published: 08 August 2025;  doi: 10.21926/obm.geriatr.2503320

The shrinkage of muscles with age, beginning at 30 y and accelerating in old age, is due largely to atrophy of fast-twitch muscle fibers (FT) partly from disuse. It was our purpose to develop an exercise program that is effective and time efficient at stimulating FT, as well as slow-twitch fibers (ST), to offset their atrophy. FT are recruited during movements requiring very high force and/or high velocity. We developed a safe exercise cycle that allows a person to ‘accelerate’ with the maximal effort needed to rec [...]

by Marta I. Litter

Received: 15 September 2025;  Published: 22 September 2025;  doi: 10.21926/aeer.2503029

by Lúcia Bacalhau  and Patrícia Pontífice-Sousa

Received: 19 September 2024;  Published: 06 February 2025;  doi: 10.21926/obm.transplant.2501233

Allogeneic Stem Cells Transplantation (ASCT) and, consequently, the chronicity associated with this life event has a growing prevalence and a significant impact on the life and daily life of each person who experiences it. The growing number of ASCT survivors highlights the need to reflect on the unique challenges they face throughout their recovery. To understand the meaning of the encounter with time in the lived experience of comfort for survivors of ASCT. Qualitative approach using van Manen's phenomenology of [...]

by Negar Gorjizadeh  , Payam Saadat  , Abbas Azadmehr  and Saeed Irian

Received: 09 June 2025;  Published: 11 September 2025;  doi: 10.21926/obm.genet.2503310

Genetic factors including TNF-β and DRD2 have been considered as essential components in the etiology of migraine. Several studies have investigated the association between TNF-β +A252G or DRD2 C939T polymorphisms and migraine risk, with debatable results. We aimed to examine whether TNF-β +A252G and DRD2 C939T polymorphisms confer genetic susceptibility to migraine in a Northern Iranian case-control sample. In total, 151 migraineurs (105 with MO 46 with MA) and 144 healthy control subjects were included in this st [...]

by James D Adams

Received: 09 February 2025;  Published: 10 February 2025;  doi: 10.21926/obm.icm.2501010

Medicines used in pain and chronic pain are aimed at relieving neuroinflammation. This neuroinflammation can occur in the brain, brain stem, dorsal root ganglion and other sites. What causes neuroinflammation? Why does this neuroinflammation last for years? Are there cures for neuroinflammation?

by Filomena Emanuela Laddaga  , Tommasina Perrone  , Pellegrino Musto  , Ilaria Farella  , Stefano Martinotti  and Francesco Gaudio

Received: 22 February 2025;  Published: 18 June 2025;  doi: 10.21926/obm.transplant.2502253

Primary mediastinal large B-cell lymphoma (PMLBCL) is an aggressive B-cell malignancy that may exhibit resistance to standard chemoimmunotherapy. Novel immunotherapeutic strategies, including checkpoint inhibitors and chimeric antigen receptor T-cell (CAR-T) therapy, are being explored in cases that are refractory to treatment. We report the case of a 29-year-old patient with refractory PMLBCL who was treated with pembrolizumab as a bridging therapy followed by axicabtagene ciloleucel (CAR-T) after failing R-CHOP a [...]

by Recent Progress in Materials Editorial Office

Received: 02 January 2025;  Published: 02 January 2025;  doi: 10.21926/rpm.2501001

The editors of Recent Progress in Materials would like to express their sincere gratitude to the following reviewers for assessing manuscripts in 2024. We greatly appreciate the contribution of expert reviewers, which is crucial to the journal's editorial process. We aim to recognize reviewer contributions through several mechanisms, of which the annual publication of reviewer names is one. Reviewers can download a certificate of recognition directly from our submission system. Additionally, reviewers can sign up t [...]

by Deanna Gray-Miceli

Received: 04 February 2025;  Published: 01 August 2025;  doi: 10.21926/obm.geriatr.2503319

The purpose of this original research was to describe the lived experience and meaning of a serious fall to independently residing older adults. A qualitative phenomenological approach was utilized with a purposive sample of 19, independent, high-level functioning older adult residents of a Continuing Care Retirement Community to describe their most serious fall and its personal meaning. Traced through multiple data sources, interpretive analysis of the language expressed by older adults were integrated to support [...]

by Chuk Ling Julian Lai  , Wei Yin  and Jianwei Shi

Received: 20 July 2024;  Published: 02 March 2025;  doi: 10.21926/obm.geriatr.2501300

Based on a framework derived from theories of social integration and health, this study examined the relationships between motivation to cultivate social ties or network cultivation, and diurnal salivary cortisol in Chinese older adults. The main objective was to determine the behavioral mechanism that translated a higher motivation to cultivate social ties into healthier diurnal cortisol rhythms in 82 community-dwelling elders in Shanghai. Participants were provided four saliva samples immediately, 30 minutes, and [...]

by Deanna Gray-Miceli  and Sarah J. Ratcliffe

Received: 30 January 2024;  Published: 10 March 2025;  doi: 10.21926/obm.geriatr.2501303

This research sought to determine feasibility for RNs to use the Post Fall Index™ (PFI) and to determine if an RN could identify underlying causal event factors for falls, would it be congruent with other providers (advanced practice nurse [APN], physician [MD])? PFI data from 23 falling residents of a nursing home were compiled into clinical vignettes and reviewed by experts for underlying causal event factors/fall sub-types. RNs used the PFI for one month in practice. The RN generated the most diagnoses; pe [...]