by Nasrin Motazedian  , Masoud Mokhtari  , Negar Azarpira  , Kimia Falamarzi  , Mohsen Mohammadi  , Seyed Mohsen Dehghani  , Sarina Pourjafar  , Maryam Ataollahi  , Elaheh Esfandiari  , Mahdokht Hossein-Aghdaie  , Seyed Ali Malekhosseini  , Tayebeh Kazemi  and Mahintaj Dara

Received: 05 May 2024;  Published: 04 June 2024;  doi: 10.21926/obm.transplant.2402217

Crigler-Najjar syndrome (CNS) is a rare autosomal recessive disorder characterized by impaired bilirubin metabolism, leading to neurotoxic unconjugated bilirubin accumulation. Liver transplantation remains the only effective treatment, highlighting the need for novel diagnostic and therapeutic approaches. Long non-coding RNAs (lncRNAs) have emerged as potential biomarkers in various diseases, including cancer. This study aimed to evaluate the expression of lncRNAs HOTTIP and HOTAIR in CNS patients and healthy contr [...]

by Sandra Kiessling

Received: 06 September 2024;  Published: 15 January 2025;  doi: 10.21926/aeer.2501006

The World climate is changing, with a great impact on global food production systems. Extreme weather events, floods, wildfires and draughts are phenomena of disrupted previously stable natural weather patterns, which are vital for crop production and animal husbandry alike. Most of the World’s food is produced in temperate climatic zones rich in arable land and those are affected by the increasing unpredictability of previously naturally occurring seasons and weather conditions. This work aims to provide a possibl [...]

by Adam Resnick  , Alicia Bergman  , Rebecca Oberman  , Stephanie L. Taylor  , Emmeline Chuang  , Kelsey Cummings  and Evelyn T. Chang

Received: 20 December 2023;  Published: 31 January 2024;  doi: 10.21926/obm.icm.2401012

The Veterans Health Administration (VA) offers complementary and integrative health (CIH) therapies to Veterans with chronic pain and opioid use disorder (OUD). While CIH therapies have known benefits for chronic pain, less research exists on its use for patients with OUD. In this qualitative study, we aimed to assess provider and patient perceptions of CIH therapies for Veterans with OUD. We interviewed 45 providers involved in OUD care and 17 Veterans with OUD from five VA medical centers as part of a larger mixe [...]

by Tammie Lee Demler  , Samantha Morales  , Geoffrey Brown  , Andrea Derosas  and Claudia Lee

Received: 18 March 2024;  Published: 14 September 2024;  doi: 10.21926/obm.geriatr.2403288

There are few reports that describe incidence of hypothermia in patients treated with olanzapine. We report a case of an elderly 83-year-old black male, readmitted to the state psychiatric hospital December 2023 due to psychiatric exacerbation after 6 months of successful discharge to community, who experienced a fall and profound hypothermia with bradycardia that resulted in a 10-day acute hospitalization in January 2024. Medical workup was unrevealing except for multivessel disease found on CT stroke study of the [...]

by Hicham Bouchahta  , Zhour EL Amrani  , Siham Chafai Elalaoui  , Fatima Ouboukss  , Aziza Sbiti  , Laila Sbabou  , Thomas Liehr  , Abdelaziz Sefiani  and Abdelhafid Natiq

Received: 14 October 2024;  Published: 27 January 2025;  doi: 10.21926/obm.genet.2501282

Cat-eye syndrome (CES) is a rare genetic disease first reported in 1965. The estimated prevalence of CES is 1:50,000 to 1:150,000, and it is typically associated with an inverted duplicated small supernumerary marker chromosome (sSMC) derived from chromosome 22. The specific chromosomal band involved in CES causing partial tetrasomy is 22q11.21, where chromosomal rearrangements occur due to the presence of low-copy repeats (LCR22). The phenotype of CES is extremely diverse, ranging from normal to multiple abnormali [...]

by Fabian Banda  , Leonard Simukoko  , Mulenga Kalumba  and Mwansa Kaoma

Received: 26 September 2024;  Published: 17 April 2025;  doi: 10.21926/aeer.2502020

Aquatic weeds present significant ecological and socio-economic challenges in the Bangweulu Wetlands of northern Zambia, where their proliferation disrupts aquatic ecosystems, impedes fishing activities, and affects local livelihoods. Despite these challenges, aquatic weeds also offer a unique opportunity for sustainable biochar production, a clean alternative cooking fuel that can alleviate pressure on diminishing forest resources. This study explores the application of machine learning (ML) techniques to estimate [...]

by James David Adams

Received: 22 August 2023;  Published: 11 January 2024;  doi: 10.21926/obm.icm.2401009

Many websites are dedicated to educating the public about chronic pain and its management. The majority of these websites say there is no cure for chronic pain, but encourage patients to try exercise, diet, stress reduction and other techniques to decrease the severity of chronic pain. Patients are also taught to use oral or injected drugs to treat their chronic pain. This can be dangerous and leads to adverse events and death in some patients. The majority of these websites teach patients that chronic pain comes f [...]

by Andrea Bellieni  , Beatrice Di Capua  , Emanuele Rocco Villani  , Luca Tagliaferri  , Domenico Fusco  , Maria Antonietta Gambacorta  , Francesco Presta  , Serena Bracci  , Vincenzo Valentini  , Francesco Landi  and Giuseppe Ferdinando Colloca

Received: 17 November 2022;  Published: 13 June 2023;  doi: 10.21926/obm.geriatr.2302238

New technologies, aging-related changes, and evolution in patients' needs have led to a new scenario in all oncological fields in front of which we have to move on. Technological progress has made it possible to increase the number of patients treated, including elderly patients and generally those at higher risk of toxicity. However, this scenario has led to new problems requiring new skills to be addressed. For this reason, Gemelli-ART (Advanced Radiation Therapy) of Fondazione Policlinico Universitario A. Gemell [...]

by Recent Progress in Science and Engineering Editorial Office

Received: 22 June 2025;  Published: 23 June 2025;  doi: 10.21926/rpse.2502010

by Anita Padmanabhanunni  and Tyrone Pretorius

Received: 26 April 2023;  Published: 25 September 2023;  doi: 10.21926/obm.neurobiol.2303184

The COVID-19 pandemic was characterized as a continuous traumatic stressor and associated with high levels of posttraumatic stress disorder (PTSD). This study examines the associations between demographic factors, COVID-19-related factors (fear of COVID-19 and perceived stress), and PTSD, as well as the associations between PTSD and indices of mental health. The participants in the study were university students (n = 322) who completed the PTSD Checklist for the Diagnostic and Statistical Manual-5 (DSM-5), the Fear [...]