Table of Content

Open Access Research Article

Development of Parametric Voronoi-Based Scaffolds for Trabecular Bone Tissue Replacement Using Additive Manufacturing

Received: 07 February 2025;  Published: 28 May 2025;  doi: 10.21926/rpm.2502010

Abstract

Tissue engineering is a technique for regenerating living tissue using portions of the patient's tissue, which are dissociated into cells and cultured on biological or synthetic supports before being transferred to the patient. In this context, the present study seeks to develop implant models (scaffolds) for replacing trabecular bone tissue, with requirements such as porosity and interconnected pores. All design development was aimed at the manufacturing of scaffolds using the material extrusion additive manufactu [...]

1156 6480

Open Access Review

Emerging Progress in Nanotechnological Influence on Polymeric Textile Finishing

Received: 13 January 2025;  Published: 27 May 2025;  doi: 10.21926/rpm.2502009

Abstract

Nanotechnology has revolutionized the textile industry by introducing innovative finishing techniques that enhance the durability and performance of textile materials and the application of nanoscale/nanoparticles/nanomaterials and processes to improve the properties and performance of textiles. The synergism of textile technology and nanotechnological advancements has propelled a paradigm shift, changed the narrative, and formed novel platforms for textile surface engineering at both atomically affiliated and mole [...]

2530 20506

Open Access Original Research

The Relationship between Anger, Stress, Psychological Distress and Mood Disorders among Entrepreneurs

Received: 18 December 2024;  Published: 26 May 2025;  doi: 10.21926/obm.neurobiol.2502288

Abstract

The present study investigates the association between anger, stress, psychological distress and mood disorders among Egyptian entrepreneurs. Approach-wise, the study is quantitative, and its cross-sectional data were collected using a questionnaire. The study’s respondents are Egyptian entrepreneurs involved in several business activities. Hence, the study concluded based on 286 valid responses. We used analysis of moment structures (AMOS) software, where we conducted path analysis to conclude the results. C [...]

1146 8010

Open Access Original Research

In Silico Evaluation of Anti-SARS-CoV-2 Bioactive Compounds from Jatropha curcas

Received: 12 March 2025;  Published: 25 May 2025;  doi: 10.21926/obm.genet.2502295

Abstract

Jatropha curcas L., a medicinal shrub renowned for its diverse phytochemicals, has been traditionally used to treat various ailments, including ulcers, neoplasms, and dermatological conditions. Despite its pharmacological promise, its potential against Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) remains unexplored. This study investigates the antiviral efficacy of J. curcas phytochemicals targeting the SARS-CoV-2 main protease (Mpro), a critical enzyme for viral replication, using advanced computat [...]

1074 5802

Open Access Original Research

The Importance of Specialized Inpatient Medical Stabilization for Weight Restoration of Individuals with Extreme Eating Disorders

Received: 19 December 2024;  Published: 23 May 2025;  doi: 10.21926/rpn.2502012

Abstract

Inpatient care is a significant contributor to the health-care costs associated with the treatment of individuals with eating disorders (EDs). This study seeks to better understand the treatment outcomes of individuals with extreme EDs requiring inpatient medical stabilization at specialized medical versus nonspecialized medical units. Patients transferred via air ambulance to ACUTE Center for Eating Disorders and Severe Malnutrition (specialized care) from an outside hospital (nonspecialized care) between January [...]

924 7951

Open Access Original Research

Quantitative Evaluations on Harmonic and Anharmonic Lattice Thermal Capacity of Polymers

Received: 28 December 2024;  Published: 22 May 2025;  doi: 10.21926/rpm.2502008

Abstract

So-called ‘Generalized Skettrup Model(s)’ (GSMs) of different (1D, 2D, 3D) spatial dimensionalities are used at simulations on temperature-dependent harmonic and anharmonic fractions of lattice thermal capacity of polyethylene and polypropylene with crystalline and/or amorphous atomic structures of limited spatial extents. Basic equations of the GSM slot in explicitly quantization effects of the single-particle and many-particle energy levels of spatially confined phonons. The harmonic lattice thermal c [...]

850 4823

Open Access Case Report

Unraveling and Expanding the Genotypic Spectrum of Kabuki Syndrome with Identification of de Novo Protein-Truncating Mutations in the KMT2D Gene: Insights into the Role of Premature Stop Codons in the Etiology of the Disorder

Received: 16 January 2025;  Published: 21 May 2025;  doi: 10.21926/obm.genet.2502294

Abstract

Kabuki Syndrome (KS) is a rare, multisystem congenital disorder with five foremost clinical manifestations encompassing dysmorphic facial characteristics, postnatal growth constraint, craniofacial/skeletal anomalies, mild to moderate intellectual disability, and dermatoglyphic abnormalities. We analyzed two unrelated Iranian patients suspected of having KS using whole-exome sequencing. An in silico analysis was performed to evaluate the potential effects of the discovered variants on the structure and function of t [...]

1037 6030

Open Access Original Research

The Intra-Institutional Waste Management in Montevideo Healthcare Centers

Received: 23 September 2024;  Published: 20 May 2025;  doi: 10.21926/aeer.2502023

Abstract

Healthcare Waste (HCW) management is a pressing challenge in Latin America, where insufficient regulatory enforcement, poor segregation practices, and the lack of accurate generation data hinder sustainable waste management. This study presents a methodological proposal for the internal management of HCWs in Healthcare Centers (HCCs) in Uruguay, based on Decree 586/009 and developed through a situational diagnosis conducted at the Hospital de Clínicas "Dr. Manuel Quintela." The diagnosis involved the qualitative an [...]

1069 6396

Open Access Original Research

“It Seems to Sort of Wash My Brain Out”: The Experiences of Open-Water Swimmers with Depression

Received: 05 March 2025;  Published: 19 May 2025;  doi: 10.21926/obm.icm.2502022

Abstract

Depression is a leading cause of disability with many individuals experiencing recurrent episodes of depression across their lifetime. Existing treatment approaches have varied degrees of effectiveness, and the value of social prescribing practices is being recognised. Given the persistent nature of depression, many individuals seek out alternative methods to manage their own symptoms. Open-water swimming is becoming increasingly popular as a means of supporting mental health. There is an emerging evidence base ind [...]

889 8927

Open Access Original Research

The Contribution of Dietary Fatty Acids to Prediction of All-Cause Mortality in a Cohort of Middle-Aged Men Followed-Up for 61 Years Until Extinction

Received: 09 November 2024;  Published: 19 May 2025;  doi: 10.21926/rpn.2502011

Abstract

To describe the contribution of three classes of dietary fatty acids to all-cause mortality and age at death among middle-aged men followed up for 61 years until extinction. The cohort comprised 1712 men aged 40-59 years at entry examination in 1960, belonging to the Italian Rural Areas of the Seven Countries Study of Cardiovascular Diseases. A dietary survey allowed to estimate dietary fatty acids [saturated (SAFA), mono-unsaturated (MUFA), poly-unsaturated (PUFA) and their ratios (M/S, P/S)] that were fed as poss [...]

945 3965

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