by Victoria Rendell  , Natalie M. Bath  and Todd V. Brennan

Received: 09 May 2019;  Published: 10 March 2020;  doi: 10.21926/obm.transplant.2001104

Brazilian-born British biologist Dr. Peter Medawar played an integral role in developing the concepts of immunologic rejection and tolerance, which led to him receiving the Nobel Prize “for the discovery of acquired immunologic tolerance” and eventually made organ transplantation a reality. However, at the time of his early work in tolerance, a paradox to his theories was brought to his attention; how was pregnancy possible? Pregnancy resembles organ transplantation in that the fetus, possessing paterna [...]

by Tommy Sundqvist  , Lars Stenhammar  , Bo Tjellström  , Karl-Eric Magnusson  , Tore Midtvedt  , Elisabeth Norin  and Lotta Högberg

Received: 07 February 2020;  Published: 09 March 2020;  doi: 10.21926/obm.hg.2001043

by Fernando Cabo  and Isaac Aguaristi

Received: 01 September 2019;  Published: 05 March 2020;  doi: 10.21926/obm.icm.2001013

Several manual bodywork therapies that originated in Asia are related to the theory and practice of acupuncture and Traditional Chinese Medicine (TCM). One of the aims of these therapies is to stimulate specific points on the body called acupoints which are the same points in which needles are inserted in acupuncture. These manual therapies, however, vary in their interpretation and explanation of the theories of TCM, and even more so, in the practical way the stimulation is applied. The aim of this paper is to cla [...]

by H. Hakemi  , M. Khenkin  , R. Tamari  and D. Gal-Fuss

Received: 10 December 2019;  Published: 05 March 2020;  doi: 10.21926/rpm.2001006

In the present study, we report the experimental results related to the transient phenomenon, i.e., the time-dependent changes in the electro-optical properties of as-made polymer-dispersed liquid crystal (PDLC) films prepared by the UV-curing phase-separation method. This phenomenon occurs explicitly via polymer-induced phase separation when the matrix curing is not complete, some liquid crystal plasticized in the matrix, and some uncured pre-polymer components remain in the liquid crystal droplets. The outcome is [...]

by Yuri Shavrukov

Received: 03 March 2020;  Published: 04 March 2020;  doi: 10.21926/obm.genet.2001104

by Lucy Watts  , Joanna Smith  , Wilfred McSherry  , Michael Tatterton  and Alison Rodriguez

Received: 04 November 2019;  Published: 03 March 2020;  doi: 10.21926/obm.icm.2001012

In palliative and end of life care settings supporting people to make sense of their lives is as important as managing disease symptoms. Dignity Therapy is a validated psychotherapeutic intervention designed to bring about a sense of meaning and purpose for individuals at the end of life. Dignity Therapy has primarily been implemented and evaluated in adult palliative care settings. Prior to designing studies that evaluate Dignity Therapy for children and young people with life-limiting and life-threatening conditi [...]

by Jessica Scher Lisa  and Eric Shyman

Received: 24 October 2019;  Published: 02 March 2020;  doi: 10.21926/obm.neurobiol.2001051

With an increasing prevalence of children with Autism Spectrum Disorder (ASD) in schools, teachers are in need of different effective ways to educate these individuals who have distinctly different needs and modalities of experience. One area that has been explored is neuroeducation, or using findings from neuroscientific research to inform classroom practice. Neuroscientific findings appear to center on two main themes of neurological differences among children with ASD: sensory processing and emotional processing [...]

by Tina Huang  , Tony Hung  , S. Irene Kim  and Ka Kit Hui

Received: 07 October 2019;  Published: 02 March 2020;  doi: 10.21926/obm.icm.2001011

Acupuncture has increasingly been used to address a variety of symptoms in patients with cancer. Here we present a case to illustrate the use of acupuncture in a 35-year-old female with metastatic breast cancer who presented to the UCLA Center for East-West Medicine (CEWM) with physical and psychological symptom clusters of insomnia, anxiety, and joint pain.

by Joseph S. D'Arrigo

Received: 26 December 2019;  Published: 28 February 2020;  doi: 10.21926/obm.geriatr.2001110

Aging, hypertension, diabetes, obesity, atherosclerosis, traumatic brain injury, and other factors can all synergistically promote diverse pathological mechanisms. These risk factors trigger widespread inflammation and oxidative stress, both of which can lead to blood-brain barrier (BBB) disruption. These pathological cascades lead to neuronal Ca2+ increase, neurodegeneration, gradual cognitive/memory decline, and eventually Alzheimer's disease. In particular, more recent research indicates that chronic inflamm [...]

by Ryan L Dimmock  , Xuyiling Wang  , Yibin Fu  , Alicia J El Haj  and Ying Yang

Received: 09 December 2019;  Published: 28 February 2020;  doi: 10.21926/rpm.2001005

Advancements in surface engineering and material fabrication techniques have enabled the creation and replication of naturally occurring surface topographies or the extrapolation of natural patterns to become achievable targets. Polymers are used extensively in the field of biomedical sciences for containment, handling, and as cell culture substrates. It is well established that several polymers exhibit good biocompatibility for cell culture, with properties that include exhibiting minimal to no cytotoxicity and be [...]