by Parisa Gazerani

Received: 27 June 2020;  Published: 08 September 2020;  doi: 10.21926/obm.neurobiol.2003071

Sleep plays an important role in maintaining brain function, memory consolidation, hormonal balance, immune system function, growth, and repair. The physiological and psychological effects of disruptions in sleep highlight its importance in human health and wellness. Epigenetic roles are proposed in sleep, and circadian regulation, but only a limited number of studies have determined the mechanism that underlies the epigenetics of environmental factors interacting with the sleep, particularly the ones related to sl [...]

by Yashiro Rojas  , Evana Halaka  , Mary Hanna  , Alex Sidotu  , Jehan Joma  , Mina Mikhael  , Roger A. Lalancette  and Ivan Bernal

Received: 26 July 2020;  Published: 07 September 2020;  doi: 10.21926/acr.2003008

The compound, [cis-dichloro-(tris-2-amino(ethylamine))cobalt(III)]chloride hydrate, [cis-Cl2-(tren)Co(III)Cl]·H2O, a conglomerate crystallizing in P21 with Z = 4 (Z’ = 2), has been used as a precursor in the synthesis of a new dicobalt(III) peroxo complex: [(μ2-hydroxo)(μ2-peroxo)bis(tris-2-amino(ethylamine))di-cobalt(III)] tris(triiodide) dihydrate. This material crystallizes, without disorder, in space group P212121 with Z = 4 (Z’ = 2), thus making it, unambiguously, an example of a conglomerate. Its cell constan [...]

by Giuseppe De Benedittis

Received: 25 August 2020;  Published: 31 August 2020;  doi: 10.21926/obm.icm.2003039

by Mario F. Tecce  , Walter Milano  and Anna Capasso

Received: 26 June 2020;  Published: 31 August 2020;  doi: 10.21926/obm.icm.2003038

Adipocytes play a central role in maintaining lipid homeostasis and energy balance by storing triacylglycerols (TAGs) or releasing free fatty acids in response to changes in energy requirements. Obesity is a major risk factor for many diseases, including diabetes, hypertension, and cardiovascular disease. Besides, morbidity and mortality associated with being overweight and obese are on the rise. The development of obesity is characterized by an increase in lipid cells due to mitogenesis and differentiation, which [...]

by Renly Dutton  , Frank Abdi  , Levon Minnetyan  and James L. Sherley

Received: 22 April 2020;  Published: 28 August 2020;  doi: 10.21926/obm.transplant.2003117

Although tissue stem cells are essential for the maintenance, renewal, and repair of vertebrate organs and tissues, previously, the simple act of counting them has not been possible. For more than a half-century, progress in tissue stem cell research and medicine has been undermined by the lack of a means to determine tissue stem cell number. In particular, a major unmet need for stem cell transplantation medicine has been a way to quantify the specific dosage of tissue stem cell treatments. The counting problem pe [...]

by Marek Łożyński  , Iwona Mądrzak-Litwa  and Aleksandra Borowiak-Resterna

Received: 29 June 2020;  Published: 27 August 2020;  doi: 10.21926/acr.2003007

1-Decylbenzimidazole (dbim) copper(II) complexes formed during solvent extraction were thoroughly studied, and their structures were predicted. Density functional theory (DFT) calculations of their structures and Time-dependent DFT (TD-DFT) calculations of their spectra indicated that 1-decylbenzimidazole forms both mono- and binuclear complexes with copper(II), with coordination numbers of 4 or 5. At the molar ratio of [Cu(II)]aq/[dbim]org ≥ 1 and at [Cl-]aq ≥ 0.9 mol dm-3 in the extraction media, a binuclear 1:1 [...]

by Evelyne El Masri  and Tat-Hean Gan

Received: 28 May 2020;  Published: 27 August 2020;  doi: 10.21926/rpm.2003020

Carbon fibre reinforced polymer (CFRP) systems as sheets or plates are commonly used to strengthen and retrofit damaged reinforced concrete beams. In general, the bond between the FRP element and concrete defines the effectiveness of the externally bonded FRP materials. In most cases, the interface bonding behaviour is usually tested via static loading conditions. In this paper, the bonding is verified under dynamic conditions. Wave propagation is modelled in delaminated CFRP strengthened reinforced concrete beam. [...]

by Aline Duarte Folle  , Kimberly C Paul  , Cynthia D Kusters  , Jeff M Bronstein  , Adrienne M Keener  and Beate Ritz

Received: 30 June 2020;  Published: 26 August 2020;  doi: 10.21926/obm.geriatr.2003131

Insomnia and excessive daytime sleepiness are the most common sleep disturbances in Parkinson’s disease. This study aims at better understanding how severity of PD motor and non-motor features and dopaminergic treatments contribute to these sleep symptoms in the first decade of PD. Data from a community-based cohort of PD patients was used to model cross-sectional PD-related risk factors for insomnia and EDS sleep scores using linear regression models adjusted for age, gender, and PD duration. Longitudinal changes [...]

by Melissa Gaule  , Erin Allen  and Kathleen Benton

Received: 29 March 2020;  Published: 26 August 2020;  doi: 10.21926/obm.icm.2003037

by Michael Falkenstein

Received: 11 August 2020;  Published: 19 August 2020;  doi: 10.21926/obm.geriatr.2003130