Enhanced Long-term Antithrombogenicity Instigated by Covalently-Attached Surface Modifier on Biomedical Polymers
Abstract
2195 10509
Enhanced Long-term Antithrombogenicity Instigated by Covalently-Attached Surface Modifier on Biomedical PolymersAbstract
During a variety of medical procedures such as renal dialysis, bypass surgery, and lung transplantation patient blood is exposed to the surface of a number of polymeric materials such as polycarbonate (PC), poly (vinyl chloride) (PVC) and polysulfone (PS) for a period up to several days. Such exposure may result in undesirable protein-material interactions that can potentially trigger deleterious biological processes including thrombosis, which may be responsible for other complications such as cognitive disability [...] 2195 10509 |
Exploring Potential Neurobiological Parallels of Restrictive Behaviour: Anorexia Nervosa and Chew and Spit (CHSP)Abstract
Consensus for where along the eating disorder spectrum the pathological eating behaviour of Chew and Spit (CHSP) falls has been a point of contention in academic literature. Using the case of Mary1, a 30 year old female from Australia who has engaged in excessive restrictive behaviour, was diagnosed with anorexia nervosa (AN) and has been engaging in Chew and Spit (CHSP) behaviour for over 10 years, the current paper examines the similarities from a neurobiological perspective between restrictive behaviours (akin w [...] 2028 11824 |
The Use of ECMO in Treatment of Post Liver Transplant Septic ShockAbstract
Liver transplant is a life-saving therapy for patients with end stage liver disease and liver cancer. Liver re-transplantation cases are usually more challenging and riskier than primary surgery, they require careful consideration and larger recourse utilization. Decision making on who receives transplantation surgery includes individual patient risks and benefits, physician judgment, specific transplant center policies, surgical experience, geographic organ availability, and ethical considerations. Several mathema [...] 1910 12116 |
Breeding “CRISPR” Crops1Abstract
The challenges which face the world today can be summed up in a few words: An increasingly congested world with dwindling areas of viable cultivated land and accelerating climate instability. The combined effect of these realities, together with the trend of striving to extend the average human life, puts the world on the path toward future catastrophe. This situation makes it imperative to seek realistic and practical solutions, which must be able to address food shortages and climate problems in a timely manner. [...] 2069 9682 |
Testing the Correlation between Prior Knowledge of - and Visualisation Guided WTPs for Reducing the Visual Impacts Visual from Offshore Wind FarmsAbstract
Visual external costs are significant elements in the cost-benefit analysis of wind farm locations. This has been demonstrated well in the literature. However, in the assessment of the visual costs, a large share of the earlier studies used no or only simplistic visualizations of the visual impacts at stake. The cost estimates thus rely on the respondents’ ability to imagine the visual impacts associated with wind turbines of different sizes and at different locations. This has been argued to potentially reduce the [...] 1973 9173 |
Human Gut Microbiota: Friend or Foe?by
Abstract
The human gut is a house to approximately 1,000 different species of bacteria. The bacterial composition of gut microbiota is influenced by several factors, including age, sex, mode of delivery, geographical location, ethnicity, diet, drugs, and administration of prebiotics and/or probiotics. Similarly, human health depends on the composition of gut microbiome, with gut bacteria playing a crucial role in human physiology. For instance, gut microbiota synthesizes vitamins and amino acids, and affects the biotransfor [...] 1576 8691 |
Neurostimulation Approaches in the Treatment of Severe Anorexia Nervosaby
Abstract
Psychiatry is seeking interventions that could reliably sustain weight gain and psychosomatic recovery of patients with severe anorexia nervosa (AN). Currently, patients with AN, even after receiving individually-tailored therapeutic interventions, often relapse following marginal weight restoration. Also, the evidence regarding the effectiveness of psychotropic medications in relieving and treating AN symptomology is limited. The research in the field is aiming to mitigate shortcomings associated with common pract [...] 2039 13701 |
Preclinical Investigation of the Acute Effects of Trigonella foenum-graecum Seed Powder on Blood Glucose in Normal and Alloxan-Induced Diabetic RabbitsAbstract
To investigate the blood glucose lowering effect of the seed powder of T. foenum-graecum Linn (Papilionaceae) in normal and alloxan-induced diabetic rabbits. The blood glucose lowering effect of the seed powder was determined in normal and alloxan-induced (100 mg/kg, i.v.) diabetic rabbits, after oral administration of doses of 50, 100 and 150 mg/kg body weight. Blood samples were collected from the marginal ear vein before and also at 4, 6, 8, 10, 12, 16, 18, 20 and 24 h after drug administration and blood glucose [...] 2127 10479 |
Detection of Circulating Tumor DNA in Solid TumorsAbstract
Cancer is characterized by sequential and progressive genetic and epigenetic alterations in key proto-oncogenes and tumor suppressor genes, which ultimately lead to tumor development. Advances in the technology of analysis of molecular mechanisms have increased the efficiency of clinical management of cancer patients. Recent years have witnessed a progressive development in technologies that enable the detection of specific molecular abnormalities associated with various types of solid tumors in body fluids, a proc [...] 2068 11139 |
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