by Habibur P. Rahman  , DaiRicky H Bhogal  and Patricia F. Lalor

Received: 05 February 2018;  Published: 16 May 2018;  doi: 10.21926/obm.hg.1802007

Background & Aims. Acute kidney injury (AKI) is a serious complication of liver surgery and associated with significant morbidity and mortality. The incidence of AKI following hepatic surgery can be as high as 94%, with highest rates seen following orthotopic liver transplantation, particularly when extended criteria grafts are used. Strategies to identify patients at risk of AKI may enable early interventions to prevent or minimise AKI. Methods. A systematic review was conducted using PubMed, Medline, Cochrane and [...]

by Hidehiro Kamezaki  , Dai Sakamoto  , Daiki Okamura  , Koji Nakagawa  and Naoya Kato

Received: 10 December 2017;  Published: 14 March 2018;  doi: 10.21926/obm.hg.1801006

(1) Background: Endoscopy has become the primary diagnostic and treatment technique for non-variceal upper gastrointestinal bleeding. Despite advancements in therapeutic methods and instrumentation, endoscopic hemostatic failure occurs in 10% of patients. This study aimed to analyze endoscopic findings in patients with failed hemostasis and to elucidate strategies for endoscopists and gastroenterologists to facilitate improved treatment outcomes. (2) Methods: A total of 128 patients received hemostatic treatment fo [...]

by Tatsuo+ Kanda  , Shunichi Matsuoka  and Mitsuhiko Moriyama

Received: 18 October 2017;  Published: 29 October 2017;  doi: 10.21926/obm.hg.1704005

(This is review and no abstract)

by Koji Takahashi  , Tatsuo Kanda  , Yuki Haga  , Reina Sasaki  , Masato Nakamura  , Shuang Wu  , Shin Yasui  , Hidehiro Kamezaki  and Osamu Yokosuka

Received: 23 June 2017;  Published: 27 July 2017;  doi: 10.21926/obm.hg.1703004

(1) Background: Infection with hepatitis B virus (HBV) infection during pregnancy occasionally raises concerns, including acute exacerbation and the potential for mother-to-child transmission. (2) Case Report: Here, we present a case of a female patient with a chronic HBV infection who was treated with tenofovir disoproxil fumarate (TDF) and had a normal pregnancy and delivery. Furthermore, the use of TDF, HBV vaccination and passive immunization of her child with hyperimmune hepatitis B immunoglobulin successfully [...]

by Tomomi Kogiso  , Mutsuki Kobayashi  , Kuniko Yamamoto  , Yuichi Ikarashi  , Kazuhisa Kodama  , Makiko Taniai  , Nobuyuki Torii  , Kazunari Tanabe  , Hideki Ishida  , Shohei Fuchinoue  , Hiroto Egawa  , Masakazu Yamamoto  , Etsuko Hashimoto  and Katsutoshi Tokushige

Received: 08 February 2017;  Published: 06 April 2017;  doi: 10.21926/obm.hg.1702003

Background: Hepatitis C virus (HCV) infection frequently occurs in recipients of liver or kidney transplants (LT/KT). Interferon (IFN)-based therapies are used to treat HCV, but their efficacy is low. Methods: We report 24 patients who received HCV therapy after LT/KT. Design, Setting, and Participants-Twelve LT and 12 KT recipients (median age, 59 years; 15 males; 21 serological type 1) were enrolled, of whom eight (six with LT) were treated with IFN-based therapy. Twelve received direct-acting antiviral drugs [ [...]

by Tatsuo Kanda  and Osamu Yokosuka

Received: 22 January 2017;  Published: 03 February 2017;  doi: 10.21926/obm.hg.1701002

by Hidehiro Kamezaki  , Tatsuo Kanda  , Osamu Yokosuka  , Yasunori Kasahara  and Takayuki Sakurai

Received: 16 November 2016;  Published: 21 January 2017;  doi: 10.21926/obm.hg.1701001

(1) Background: Preventative treatment for Pneumocystis jirovecii pneumonia (PCP) has been recommended for patients receiving ≥20 mg/day prednisolone. We describe a patient who developed PCP while receiving a dose of 15 mg/day prednisolone, and consider criteria for the initiation of preventative therapy for PCP in patients with autoimmune hepatitis (AIH) treated with prednisolone. (2) Case Report: A 71-year-old woman initially possessed dark-colored urine, white stool, and decreased appetite, which indicated hepat [...]

by Rayone Moreira Costa Veloso Souto  , Rafael Belo Corassa  , José Veloso Souto Júnior  , Elaine Leandro Machado  and Otaliba Libânio de Morais Neto

Received: 12 September 2025;  Published: 27 March 2026;  doi: 10.21926/obm.geriatr.2601337

Elder abuse is a global public health issue, with consequences on individual health, increased burden on healthcare systems, and high social costs. The study aimed to estimate the prevalence of family violence among older adults in Brazil and analyze its association with disability, comorbidities, functional limitation, and sociodemographic characteristics. Cross-sectional study using data from the 2019 National Health Survey (PNS 2019), including older adults aged 60 years or older. Bivariate and multiple logistic [...]

by Joshua M. Baruth  , Jennifer Geske  , Elizabeth Sokolowski  and Maria I. Lapid

Received: 14 October 2025;  Published: 10 March 2026;  doi: 10.21926/obm.geriatr.2601336

Schizophrenia spectrum disorders (SSDs) are complex conditions with chronic symptoms and impairments associated with greater risk for physical comorbidity and early mortality. Understanding end-of-life care in older adults with SSDs is crucial for improving geriatric psychiatric care and identifying healthcare disparities. A cohort of 254 older adult decedents with a history of schizophrenia or schizoaffective disorder was identified using the Rochester Epidemiology Project. A control group of 254 older adult deced [...]

by Isabelle Wallach  , Julie Beauchamp  , Tamara Sussman  , Arianne Laplante  and Patrick Durivage

Received: 08 October 2025;  Published: 11 February 2026;  doi: 10.21926/obm.geriatr.2601335

The sexuality of older adults at advanced stages of illness, or at the end of life, remains a taboo topic that is rarely addressed in the literature and in practice. As a result, the knowledge base informing the support needs of older adults at the final stages of life with regards to sexuality remains scant. The present study seeks to explore experiences of sexuality in older adults with serious illness or receiving palliative care, focusing specifically on the place of sexuality in their lives, the forms of sexua [...]