by Jasmin Hundal  and Mariam AlHilli

Received: 19 August 2024;  Published: 19 March 2025;  doi: 10.21926/obm.geriatr.2501304

Elderly patients with ovarian and pancreatic cancer frequently experience malnutrition and sarcopenia, which negatively impact treatment tolerance, functional outcomes, and survival. The increasing use of neoadjuvant chemotherapy in this population necessitates structured interventions to mitigate these challenges. While prehabilitation has shown promise in enhancing treatment tolerance and quality of life, its role during chemotherapy remains underexplored. This prospective study evaluates the feasibility and impa [...]

by Deanna Gray-Miceli  and Sarah J. Ratcliffe

Received: 30 January 2024;  Published: 10 March 2025;  doi: 10.21926/obm.geriatr.2501303

This research sought to determine feasibility for RNs to use the Post Fall Index™ (PFI) and to determine if an RN could identify underlying causal event factors for falls, would it be congruent with other providers (advanced practice nurse [APN], physician [MD])? PFI data from 23 falling residents of a nursing home were compiled into clinical vignettes and reviewed by experts for underlying causal event factors/fall sub-types. RNs used the PFI for one month in practice. The RN generated the most diagnoses; pe [...]

by Sudha Ramaprasad  , Atmakur Snigdha  , Nandi Krishnamurthy Manjunath  and Vijaya Majumdar

Received: 14 October 2024;  Published: 03 March 2025;  doi: 10.21926/obm.geriatr.2501302

The COVID-19 pandemic has increased stress and disrupted routines affecting the psycho-social health of older adults, a vulnerable section of the population. Yogic practices have shown the potential to reduce stress, inflammation, and psychological health among other benefits. Hence, we explored the benefits of regular yoga practice on specific key mental health attributes in older adults amidst the pandemic. Using a case-control design, older adults (n = 54) who had been regularly practising yoga for the past six [...]

by Cesar Augustus Zocoler de Sousa  , Ana Paula Renno Sierra  , Giscard Humberto Oliveira Lima  , Bryan Steve Martínez Galán  , Hermes Vieira Barbeiro  , Heraldo Possolo de Souza  and Maria Fernanda Cury-Boaventura

Received: 20 August 2024;  Published: 28 February 2025;  doi: 10.21926/obm.geriatr.2501301

This study compared markers of muscle damage and myokines between adult and middle-aged runners before and after the marathon. Seventy-four male runners: 48 adults aged 30-44 years (AA group), and 26 middle-aged individuals aged 45-59 years (MA group) participated of the study. Blood samples were collected 24 hours before, immediately after, 24 hours and 72 hours after the marathon to measure skeletal and cardiac muscle damage markers (CK, LDH, troponin, and proBNP) and myokines (IL-6, IL-15, decorin, BDNF, GDF-15, [...]

by Chuk Ling Julian Lai  , Wei Yin  and Jianwei Shi

Received: 20 July 2024;  Published: 02 March 2025;  doi: 10.21926/obm.geriatr.2501300

Based on a framework derived from theories of social integration and health, this study examined the relationships between motivation to cultivate social ties or network cultivation, and diurnal salivary cortisol in Chinese older adults. The main objective was to determine the behavioral mechanism that translated a higher motivation to cultivate social ties into healthier diurnal cortisol rhythms in 82 community-dwelling elders in Shanghai. Participants were provided four saliva samples immediately, 30 minutes, and [...]

by Byron J. Hoogwerf

Received: 09 July 2024;  Published: 20 February 2025;  doi: 10.21926/obm.geriatr.2501299

Sarcopenia is more common in persons with type 2 diabetes mellitus (T2DM) than in persons without diabetes. There is overlap of some pathophysiologic features of sarcopenia and T2DM. In addition, the risk for sarcopenia is associated with common complications of T2DM including renal disease, cardiovascular disease and neuropathy. Glycemic control in T2DM may have some benefits on sarcopenia. The specific effects of glucose lowering agents on sarcopenia suggest that metformin, insulin, thiazolidinediones and GLP1 re [...]

by Ana Marta Menezes  , Dalila Silva  , Catarina Simões  and Rita Figueiredo

Received: 29 October 2024;  Published: 18 February 2025;  doi: 10.21926/obm.geriatr.2501298

Chronic Kidney Disease is characterized by progressive, persistent, and irreversible loss of kidney function, with a high prevalence and increasing trend in the population. An important observation, common to all recent studies, is the constant changes experienced by these individuals. Analytical changes, health status and the patient's preferences should be considered when planning anticipatory care at any phase of the disease. To comprehend the significance of the Anticipatory Care Plan for Patients with End-Stag [...]

by Urs Nydegger  and Paul Imbach

Received: 18 July 2024;  Published: 23 January 2025;  doi: 10.21926/obm.geriatr.2501297

In addition to their hemostatic functions, platelets play an essential role in immunologic interactions, which is confirmed by the observation of an increase in platelet counts in patients with immune-related thrombocytopenia and other autoimmune diseases after immunomodulatory treatment with intravenous human immunoglobulin concentrate. The mechanisms of action of this biological therapeutic option induce the development of therapeutic monoclonal antibodies, agonists, and antagonists that target the complex pathop [...]

by Harnish P Patel  , Faidra Laskou  and Elaine M Dennison

Received: 15 February 2024;  Published: 23 January 2025;  doi: 10.21926/obm.geriatr.2501296

Sarcopenia is characterised by progressive and generalised decline in muscle strength, function, and muscle mass. Now recognised as a muscle disease, it is highly prevalent in older adults, with estimates of up to 30% in some populations. Sarcopenia has a complex multifactorial aetiology, including cellular and molecular changes, chronic disease, lower physical activity as well as nutritional deficiency. Sarcopenia is associated with a range of adverse physical and metabolic outcomes leading to disability, morbidit [...]

by Diana Viafara  , Ana L. Jaramillo-Sierra  and Laura Sofía Vega-Plazas

Received: 15 June 2024;  Published: 12 January 2025;  doi: 10.21926/obm.geriatr.2501295

This research article aims to address the critical gap in understanding intimate partner violence (IPV) among older women, particularly those over 60 years of age, in Colombian society. The study explores how IPV manifests during the later stages of life, providing insights specific to this age group. The research used qualitative methodology with 14 urban women who had experienced intimate partner violence in their later life. The study revealed that psychological violence was the most common type of abuse among o [...]