Alpha-1 Antitrypsin Deficiency and Lung Transplantation: A Clinical Case






Abstract
(ISSN 2577-5820)
OBM Transplantation is an international peer-reviewed Open Access journal, which covers all evidence-based scientific studies related to transplantation, including: transplantation procedures and the maintenance of transplanted tissues or organs; assimilation of grafted tissue and the reconstitution of removed organs or parts of organs; transplantation of heart, lung, kidney, liver, pancreatic islets and bone marrow, etc. Areas related to clinical and experimental transplantation are also of interest.
OBM Transplantation is committed to rapid review and publication, and we aim at serving the international transplant community with high accessibility as well as relevant and high quality content.
We welcome original clinical studies as well as basic science, reviews, short reports/rapid communications, case reports, opinions, technical notes, book reviews as well as letters to the editor.
Archiving: full-text archived in CLOCKSS.
Rapid publication: manuscripts are undertaken in 8 days from acceptance to publication (median values for papers published in this journal in 2021, 1-2 days of FREE language polishing time is also included in this period).
Special Issue
Lung Transplant
Submission Deadline: February 28, 2017 (Closed) Submit Now
Guest Editor
Kamyar Afshar, DO
Clinical Associate Professor of Medicine, Division of Pulmonary, Critical Care and Sleep Medicine, San Diego, CA, USA
Research Interests: evaluation and management of lung transplantation; alpha 1 antitrypsin deficiency/copd and advanced stages management; sarcoidosis; lymphangioleiomyomatosis and interstitial lung disease management; phenotypic variance in cystic fibrosis
Publication
Alpha-1 Antitrypsin Deficiency and Lung Transplantation: A Clinical Caseby
![]() ![]() ![]() ![]() ![]() ![]() Abstract BACKGROUND: α1-antitrypsin deficiency is the most common hereditary disorder in adults and is associated to an increased risk of developing lung emphysema. METHODS: With this case report, we describe the case of a 54 years old patient, who underwent bilateral lung transplantation due to alpha-1 antitrypsin deficiency emphysema.
RESULTS: [...] |
Case of Lung Transplantation in a Recipient with Emphysema: Importance of Determining Alpha 1-Antitrypsin Deficiency Status for Lung TransplantationAbstract Here we present a case of a lung transplant recipient with alpha 1-antitrypsin deficiency as well as conducted a retrospective review of the United Network for Organ Sharing (UNOS) database from 1990 – 2016 specifically grouping patients with alpha-1 antitrypsin deficiency (A1ATD) and chronic obstructive pulmonary disease (COPD). |
Malignancy in the Lung Transplant Populationby
![]() ![]() Abstract The risk for developing a variety of malignancies is significantly elevated in the setting of lung transplantation. Malignancy remains among the three major causes of death in post-transplant recipients, and the relatively high risk of cancer development as well as metastatic aggression pose special threats to this population due to the need [...] |
IVIG Replacement for Hypogammaglobulinemia in Lung Transplant PatientsAbstract After lung transplant, infection is a leading contributor to morbidity and mortality, and hypogammaglobulinemia (HGG) may be an important risk factor for many of these infections. Some reports suggest that HGG not only increases the risk of various infections, but also worsens survival. The incidence of HGG has been shown to increase [...] |
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