Open Access Original Research

Systems Immunology of Colorectal Liver Metastases in the Context of Liver Transplantation: Multi-Omics Insights into Tumor Progression and Post-Transplant Recurrence

Received: 11 August 2025;  Published: 14 September 2026;  doi: 10.21926/obm.transplant.2603276

Abstract

After liver transplantation, colorectal cancer (CRC) recurrence is a serious clinical issue. This underscores the need to understand the molecular and immunometabolic axes that promote tumor development and transplant fragility. This research combines compound-gene network analysis, immune cell deconvolution, and transcriptome profiling to [...]