Calculated Human Leucocyte Antigens Evolutionary Divergence (cHED)
Abstract
(ISSN 2577-5820)
OBM Transplantation (ISSN 2577-5820) is an international peer-reviewed Open Access journal published quarterly online by LIDSEN Publishing Inc., which covers all evidence-based scientific studies related to transplantation, including: transplantation procedures and the maintenance of transplanted tissues or organs; assimilation of grafted tissue and the reconstitution of removed organs or parts of organs; transplantation of heart, lung, kidney, liver, pancreatic islets and bone marrow, etc. Areas related to clinical and experimental transplantation are also of interest.
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Special Issue
HLA in Transplantation: Typing, Matching and Outcomes
Submission Deadline: July 30, 2025 (Open) Submit Now
Guest Editors
Vikash C. Mishra, PhD, Scientist
Chimera Transplant Research Foundation, New Delhi, India
Research Interests: Human leukocyte Antigen (HLA); Histocompatibility tissue testing; Solid organ transplant; Hematopoietic stem cell transplant; Matched unrelated donor hematopoietic stem cell transplant; Stem cell registry; STR; Mitochondrial DNA analysis; Autosomal STR Analysis and Y STR DNA Analysis; CDC crossmatch; Anti HLA antibodies
Muhammad Mujtaba, MD, FASN, FAST
Associate Professor of Clinical Medicine, Division of Nephrology, University of Texas Medical Branch Galveston, Texas, USA
Research Interests: pancreas transplantation; kidney transplantation; transplant surgery; organ donation; transplant immunology
Dr. Abbas Ghazanfar, Consultant Transplant Surgeon
Renal Transplant Unit, St George's University Hospitals NHS Foundation Trust, Blackshaw Road, Tooting, London SW17 0QT, UK
Research Interests: Live donor renal transplantation; Renal Transplant in complex recipients i.e. high BMI, multiple transplants and complex anatomy; Dual Kidney transplant; Vascular access in patients with chronic kidney disease
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Publication
Calculated Human Leucocyte Antigens Evolutionary Divergence (cHED)by
Bruno A Lima
Abstract Human Leucocyte Antigens (HLA) constitute a highly polymorphic set of genes pivotal to the immune response. The HLA heterozygous advantage hypothesis assumes that heterozygous individuals at the HLA level have a wider range of peptides for T cell recognition than homozygous individuals. Consequently, they possess an enhanced capacity to trigge [...] |
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