Light-Activated Local Drug Delivery From Hydrogels: Potential for GBM Treatment







Abstract
Open Access
ISSN 2573-4407
© 2021 by the authors; CC BY 4.0 licence
OBM Neurobiology , Volume 5 , Issue 1 (2021)
Pages: 145
Published: May 2021
(This book is a printed edition that was published in OBM Neurobiology )
Cover story:Electroencephalography (EEG) is a powerful technique for studying electrical activity of the brain. The multiplicity of underlying cellular processes prevented creation of consistent quantitative models using deterministic methods of classical physics. This study undertakes a radical departure from deterministic equations of classical physics to the probabilistic reasoning of quantum mechanics. . View this paper.
Volume 5,Issue 1
Light-Activated Local Drug Delivery From Hydrogels: Potential for GBM Treatmentby
![]() ![]() ![]() ![]() ![]() ![]() ![]() Abstract Following post-operative treatment, the vast majority of GBMs recur, usually within 2 cm of the tumor resection margin. Since these tumors seldom metastasize outside the CNS, improved localized therapies should prove beneficial. Drug delivery systems (DDS) that allow control over drug release by an [...] |
Malignant Catatonia Requiring High Dose Bromocriptine: Case ReportAbstract Catatonia can occur in patients diagnosed with schizophrenia and bipolar disorder and malignant catatonia is life threatening. Anti-psychotic medications should be discontinued during acute phase of catatonia. Anti-psychotic discontinuation in catatonia is a challenge in patients maintained on long- [...] |
Smartphone Usage at Bedtime: The Effect of Sleep–Smartphone Hygiene, Trait Anxiety, and FOMO on Sleep QualityAbstract The present study was aimed to examine the relationship of sleep–smartphone hygiene, i.e., the habits of smartphone usage in the sleep environment, with the sleep quality among students and whether this relationship could be explained through psychological factors. A total of 467 Israeli college stu [...] |
Migraine as a Common Extra-Intestinal Presentation of Celiac Diseaseby
![]() ![]() ![]() ![]() ![]() ![]() Abstract Celiac disease (CD) is a common gluten-related enteropathy that presents several extra-intestinal manifestations. Migraine is globally recognized as one of the most diffuse primary headaches. The present paper aims to review the current evidence on the possible association between CD and migraine. B [...] |
Case Report of Lambert Eaton Myasthenic Syndrome in a Patient with Small Cell Lung Cancer on Immune Checkpoint Inhibitor Therapyby
![]() ![]() ![]() ![]() ![]() ![]() ![]() Abstract Lambert Eaton myasthenic syndrome (LEMS) is a rare autoimmune neuromuscular junction disorder involving loss of functional pre-synaptic P/Q-type voltage-gated calcium channels. Many cases occur as a paraneoplastic disorder, often in small cell lung cancer (SCLC). Recently, immune checkpoint inhibito [...] |
Prenatal and Preimplantation Genetic Diagnosis of Huntington's DiseaseAbstract Huntington’s disease (HD) is an autosomal dominant disease that immensely impacts the affected families. However, the transmission of the disease from carriers to their offspring could be prevented. Prenatal diagnosis (PND) and preimplantation genetic diagnosis (PGD) are the only two available repro [...] |
Quantum Theory of EEG with Application to the Single-Trial ERP AnalysisAbstract The probabilistic formalism of quantum mechanics is used to quantitatively link the electroencephalogram (EEG) with the underlying microscale activity of cortical neurons. Previous approaches applied methods of classic physics to reconstruct the EEG&l [...] |
N-Type Calcium Channels Control GABAergic Transmission in Brain Areas related to Fear and Anxietyby
![]() ![]() ![]() ![]() ![]() ![]() ![]() Abstract N-type (CaV2.2) calcium channels are key for action potential-evoked transmitter release in the peripheral and central nervous system. Previous studies have highlighted the functional relevance of N-type calcium channels at both the peripheral and central level. In the periphery, N-type calcium chan [...] |
Medical Hypothesis: Deep Brain Stimulation for Intractable MigraineAbstract Deep Brain Stimulation (DBS) has been introduced as an innovative treatment for several neurological disorders, including Parkinson’s disease, essential tremor, and dystonia and it has been proven effective in helping individuals affected by these disorders; hence, enhancing their quality of life. D [...] |
Acknowlegement to Reviewers of OBM Neurobiology in 2020Abstract The editors of OBM Neurobiology would like to express their sincere gratitude to the following reviewers for assessing manuscripts in 2020. We greatly appreciate the contribution of expert reviewers, which is crucial to the journal's editorial process. We aim to recognize reviewer contributions thro [...] |
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