(ISSN 2577-5790)
OBM Genetics is an international Open Access journal published quarterly online by LIDSEN Publishing Inc. It accepts papers addressing basic and medical aspects of genetics and epigenetics and also ethical, legal and social issues. Coverage includes clinical, developmental, diagnostic, evolutionary, genomic, mitochondrial, molecular, oncological, population and reproductive aspects. It publishes a variety of article types (Original Research, Review, Communication, Opinion, Comment, Conference Report, Technical Note, Book Review, etc.). There is no restriction on the length of the papers and we encourage scientists to publish their results in as much detail as possible.
Special Issue
Molecular, Cellular, and Genomic Insights into Thrombosis and Hemostasis
Submission Deadline: January 31, 2027 (Open) Submit Now
Guest Editor
Akbar Dorgalaleh, PhD
Hamin Pazhuhan Tis Institute, Tehran, Iran
Research Interests: Molecular hematology; hematology; thrombosis and hemostasis; cloning; PCR; cell culture; RNA extraction; molecular genetics; DNA sequence analysis; CRISPR/CAS; gene editing; gene therapy
Co-Editor
Mahmood Shams, PhD
Cellular and Molecular Biology Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran.
Research Interests: Thrombosis and hemostasis; molecular hematology; PCR; RNA extraction; molecular genetics; DNA sequence analysis; cell culture
About This Topic
Thrombosis and hemostasis represent critical physiological processes whose dysregulation underlies numerous cardiovascular, cerebrovascular, and hematological disorders. Recent advances in molecular biology, genomics, gene editing technologies, cellular imaging, and systems biology have revolutionized our understanding of the intricate mechanisms governing platelet function, coagulation cascades, endothelial regulation, and fibrinolysis. This special issue, "Molecular, Cellular, and Genomic Insights into Thrombosis and Hemostasis" aims to showcase cutting-edge research that illuminates the cellular, molecular, and genetic underpinnings of hemostatic balance and thrombotic disease.
We invite contributions exploring novel signaling pathways, genetic determinants, mutation detection, gene editing and gene therapy approaches, biomarker discovery, and innovative therapeutic targets in thrombosis and hemostasis. Topics of particular interest include platelet activation mechanisms, endothelial dysfunction, coagulation factor regulation, anticoagulant pathways, genetic variants and mutations associated with bleeding and thrombotic disorders, CRISPR-based therapeutic strategies, viral and non-viral gene delivery systems, pharmacogenomics of antithrombotic therapy, thrombus resolution, and the intersection of hemostasis with inflammation and immunity. Both original research articles and comprehensive reviews are welcome. This collection seeks to bridge fundamental discoveries with clinical implications, fostering translational insights that may improve diagnosis, risk stratification, and therapeutic interventions for thrombotic and hemorrhagic disorders.
Keywords
Thrombosis; hemostasis; gene editing; genetic mutation; coagulation disorders
Manuscript Submission Information
Manuscripts should be submitted through the LIDSEN Submission System. Detailed information on manuscript preparation and submission is available in the Instructions for Authors. All submitted articles will be thoroughly refereed through a single-blind peer-review process and will be processed following the Editorial Process and Quality Control policy. Upon acceptance, the article will be immediately published in a regular issue of the journal and will be listed together on the special issue website, with a label that the article belongs to the Special Issue. LIDSEN distributes articles under the Creative Commons Attribution (CC BY 4.0) License in an open-access model. The authors own the copyright to the article, and the article can be free to access, distribute, and reuse provided that the original work is correctly cited.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). Research articles and review articles are highly invited. Authors are encouraged to send the tentative title and abstract of the planned paper to the Editorial Office (genetics@lidsen.com) for record. If you have any questions, please do not hesitate to contact the Editorial Office.
Welcome your submission!
Publication
Prenatal Diagnosis of Severe Factor VII Deficiency in the Setting of Maternal Breast CancerAbstract Congenital factor VII (FVII) deficiency is the most common rare bleeding disorder (RBD), presenting with various clinical manifestations. Given the heightened risk of life-threatening bleeding and fatal hemorrhagic complications, prompt detection of the disorder is critical, especially in cases with low FVII levels and a history of familial [...] |
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| CiteScore | SJR | SNIP |
| 0.7 | 0.147 | 0.167 |
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