Special Issue

Molecular, Cellular, and Genomic Insights into Thrombosis and Hemostasis

Submission Deadline: January 31, 2027 (Open) Submit Now

Guest Editor

Akbar Dorgalaleh, PhD

Hamin Pazhuhan Tis Institute, Tehran, Iran

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Research Interests: Molecular hematology; hematology; thrombosis and hemostasis; cloning; PCR; cell culture; RNA extraction; molecular genetics; DNA sequence analysis; CRISPR/CAS; gene editing; gene therapy

Co-Editor

Mahmood Shams, PhD

Cellular and Molecular Biology Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran.

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Research Interests: Thrombosis and hemostasis; molecular hematology; PCR; RNA extraction; molecular genetics; DNA sequence analysis; cell culture

About This Topic

Thrombosis and hemostasis represent critical physiological processes whose dysregulation underlies numerous cardiovascular, cerebrovascular, and hematological disorders. Recent advances in molecular biology, genomics, gene editing technologies, cellular imaging, and systems biology have revolutionized our understanding of the intricate mechanisms governing platelet function, coagulation cascades, endothelial regulation, and fibrinolysis. This special issue, "Molecular, Cellular, and Genomic Insights into Thrombosis and Hemostasis" aims to showcase cutting-edge research that illuminates the cellular, molecular, and genetic underpinnings of hemostatic balance and thrombotic disease.

We invite contributions exploring novel signaling pathways, genetic determinants, mutation detection, gene editing and gene therapy approaches, biomarker discovery, and innovative therapeutic targets in thrombosis and hemostasis. Topics of particular interest include platelet activation mechanisms, endothelial dysfunction, coagulation factor regulation, anticoagulant pathways, genetic variants and mutations associated with bleeding and thrombotic disorders, CRISPR-based therapeutic strategies, viral and non-viral gene delivery systems, pharmacogenomics of antithrombotic therapy, thrombus resolution, and the intersection of hemostasis with inflammation and immunity. Both original research articles and comprehensive reviews are welcome. This collection seeks to bridge fundamental discoveries with clinical implications, fostering translational insights that may improve diagnosis, risk stratification, and therapeutic interventions for thrombotic and hemorrhagic disorders.

Keywords

Thrombosis; hemostasis; gene editing; genetic mutation; coagulation disorders 

Manuscript Submission Information

Manuscripts should be submitted through the LIDSEN Submission System. Detailed information on manuscript preparation and submission is available in the Instructions for Authors. All submitted articles will be thoroughly refereed through a single-blind peer-review process and will be processed following the Editorial Process and Quality Control policy. Upon acceptance, the article will be immediately published in a regular issue of the journal and will be listed together on the special issue website, with a label that the article belongs to the Special Issue. LIDSEN distributes articles under the Creative Commons Attribution (CC BY 4.0) License in an open-access model. The authors own the copyright to the article, and the article can be free to access, distribute, and reuse provided that the original work is correctly cited.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). Research articles and review articles are highly invited. Authors are encouraged to send the tentative title and abstract of the planned paper to the Editorial Office (genetics@lidsen.com) for record. If you have any questions, please do not hesitate to contact the Editorial Office.

Welcome your submission!