Table of Content

Open Access Short Review

The Application of Next-Generation Sequencing in Leukemia

Received: 02 May 2025;  Published: 25 December 2025;  doi: 10.21926/obm.genet.2504321

Abstract

Leukemia is a heterogeneous group of hematologic malignancies characterized by the dysfunctional proliferation of white blood cells in the bone marrow. Genetic alterations are important risk factors for the development and progression of leukemia, and their detection is crucial. Although many genetic techniques, including karyotyping, fluorescence in situ hybridization (FISH), and polymerase chain reaction (PCR), have provided valuable information, they all have the limitation of incomplete genomic coverage. The ev [...]

463 1700

Open Access Original Research

Technology to Help People with Blindness and Intellectual Disability Manage Indoor Travel: Anticipating and Bypassing Obstacles

Received: 18 August 2025;  Published: 27 November 2025;  doi: 10.21926/obm.neurobiol.2504313

Abstract

Recent work with people with blindness and intellectual disability assessed a technology-aided program intended to help eight participants travel indoor routes to reach relevant destinations. The technology included a smartphone, two barcode readers worn by the participants at their ankles, barcodes displayed at specific points of the travel routes, and a mini speaker. The technology ensured that participants received verbal instructions on how to proceed (e.g., take a left turn, cross from one side to the other of [...]

460 1746

Open Access Review

Machine Perfusion in DCD Lung Transplantation: Advances in Preservation and Donor Pool Expansion

Received: 30 June 2025;  Published: 21 January 2026;  doi: 10.21926/obm.transplant.2601264

Abstract

To address the pressing shortage of donor lungs, Donation after Circulatory Death (DCD) transplantation has become a vital strategy for expanding the donor pool. Minimizing warm ischemic injury is crucial for optimizing organ viability and function. This review synthesizes current evidence on Normothermic Regional Perfusion (NRP) and Ex-Vivo Lung Perfusion (EVLP) in DCD lung transplantation. Analysis reveals their growing efficacy in minimizing ischemic damage, facilitating organ assessment, and expanding the trans [...]

451 1584

Open Access Editorial

Acknowledgment to Reviewers of Journal of Energy and Power Technology in 2025

Received: 04 January 2026;  Published: 04 January 2026;  doi: 10.21926/jept.2601001

Abstract

The editors of Journal of Energy and Power Technology would like to express their sincere gratitude to the following reviewers for assessing manuscripts in 2025. We greatly appreciate the contribution of expert reviewers, which is crucial to the journal's editorial process. We aim to recognize reviewer contributions through several mechanisms, of which the annual publication of reviewer names is one. Reviewers can download a certificate of recognition directly from our submission system. Additionally, reviewers can [...]

447 981

Open Access Perspective

Optimizing Psychopharmacotherapy Using Personality Biomarkers: A Seven-Factor Model Perspective

Received: 19 September 2025;  Published: 26 January 2026;  doi: 10.21926/obm.neurobiol.2601320

Abstract

Personalized psychopharmacotherapy remains a critical yet underdeveloped frontier in psychiatry, as traditional approaches often fail to address substantial interindividual variability in drug efficacy and tolerability. While demographic, clinical, and genetic factors have improved treatment precision, they do not fully account for observed heterogeneity. Recent advances highlight the promise of personality traits, particularly as operationalized by Cloninger’s Seven-Factor Model, as novel biomarkers for treatment [...]

447 1198

Open Access Original Research

Wind Turbine Tower Structural and Cost Optimisation within Acceptable Structural Integrity

Received: 26 June 2025;  Published: 13 February 2026;  doi: 10.21926/jept.2601003

Abstract

As the demand for cleaner-greener energy surges owing to more nations adopting Net Zero Emission by 2050, wind turbine (WT) technology is increasingly poised as one of the technologies to match the demand. Capacity building in the development of cost-effective WT tower with improved reliability and safety has become critical to delivering Net Zero mandate. This research demonstrates implementation of Taguchi Design of Experiment (DoE) in conjunction with Signal-to-noise ratio (S/N) to optimise both structural desig [...]

445 1495

Open Access Review

Genetic and Clinical Features of Tuberous Sclerosis Patients from the Republic of Bashkortostan

Received: 29 September 2025;  Published: 08 January 2026;  doi: 10.21926/obm.genet.2601323

Abstract

Tuberous sclerosis (TS) is one of the most common hereditary tumor syndromes, occurring with an average incidence of 1 in 9,000 newborns worldwide. The disease manifests itself through the development of tumors of the brain, kidneys, heart, lungs, and skin, along with characteristic depigmented spots. Tuberous sclerosis is caused by germline variants in the TSC1 (encoding hamartin) and TSC2 (encoding tuberin) genes. The hamartin-tuberin protein complex, together with the TBC1D7 molecule, inhibits the serine/threoni [...]

441 1197

Open Access Original Research

Compassionate Mind Training for All: An Evaluation of a One-Day Compassionate Mind Training Workshop for Mental Health NHS Staff as Part of Compassion Focused Staff Support

Received: 13 October 2025;  Published: 13 February 2026;  doi: 10.21926/obm.icm.2601009

Abstract

It has become increasingly evident that individuals who work in the NHS can be heavily impacted by the nature of their work; for instance, PTSD, work related burnout, vicarious trauma, moral injury, anxiety, and depression. In turn, individuals who experience said psychological difficulties often require work-related mental health leave from work. This paper examines the experience of a One-day Compassionate Mind Training workshop (CMT), available for all NHS staff. This day has an emphasis on developing multidirec [...]

438 1495

Open Access Interview

An Interview with Dr. Blanca Hernandez-Ledesma

Received: 28 August 2025;  Published: 09 October 2025;  doi: 10.21926/rpn.2504022

435 1632

Open Access Original Research

Restoring the Resilience of Water-Energy-Food Nexus Based on Desalination through Biomass Management: Case Study West Mani, Greece

Received: 03 November 2025;  Published: 01 March 2026;  doi: 10.21926/aeer.2601005

Abstract

Mediterranean regions like West Mani, Greece, face escalating water scarcity exacerbated by climate variability and seasonal tourism peaks, straining the water-energy-food (WEF) nexus. Olive cultivation, central to the region’s economy and culture, generates substantial underutilized biomass residues that increase wildfire risk if left unmanaged. At the same time, water supply increasingly relies on energy-intensive desalination and pumping. This study addresses the gap in integrated, place-based WEF nexus applicat [...]

434 1423

Open Access Original Research

Psychometric Properties of a Scale to Measure Family Inclusion in Mexican Adults

Received: 20 June 2025;  Published: 17 December 2025;  doi: 10.21926/obm.geriatr.2504332

Abstract

This study aimed to evaluate the psychometric properties of the Family Inclusion Scale (FIS) for administration to adults and older Mexican adults. To this end, a questionnaire was structured with scales to evaluate family inclusion, loneliness, and perceived stress; the last two scales were previously validated. The sample (n = 347) consisted of young university adults aged 20 to 24 years and their grandparents aged 60 years. The conceptual emphasis of the Family Inclusion Scale generated was the identification of [...]

433 1220

Open Access Original Research

Hydroclimatic Variability and Precipitation Extremes in Sindh under a Changing Climate

Received: 12 August 2025;  Published: 24 February 2026;  doi: 10.21926/aeer.2601004

Abstract

Sindh Province, Pakistan, is highly vulnerable to hydroclimatic extremes, necessitating a detailed understanding of its precipitation patterns for effective water management. This study assesses spatiotemporal precipitation dynamics across Sindh from 2001 to 2024 by integrating satellite-based CHIRPS data, in situ observations from the Climate Knowledge Portal (CKP), and CMIP6 climate model projections. Validation results show strong agreement between CHIRPS and ground data (R ≈ 0.87, d ≈ 0.93), confirming the sate [...]

431 1233

Open Access Original Research

Promising Electrocatalytic Systems 2,5-di-Me-Pyrazine-di-N-Oxide - Cyclohexanol - Single-Walled and Multi-Walled Carbon Nanotubes for the Simultaneous Metal-Free Oxidation of Cyclohexanol at Anode and Release of Hydrogen Evolution at Cathode

Received: 07 August 2025;  Published: 26 January 2026;  doi: 10.21926/cr.2601003

Abstract

Electrocatalytic oxidation of organic compound in the absence of noble metals or their oxides as catalysts and using metal-free electrodes is a "green" electrochemical, inexpensive and attractive process for practical use in electrocatalysis, power sources and sensors. The process accompanied by the elimination of protons, is of interest both for obtaining valuable organic compounds at the anode and for the release of hydrogen evolution at the cathode. In this work, the catalytic oxidation of cyclohexanol in the pr [...]

425 1082

Open Access Original Research

Analysis of Leukocyte Telomere Length in Brazilian People Living with HIV with and Without Cancer

Received: 31 May 2025;  Published: 04 February 2026;  doi: 10.21926/obm.genet.2601326

Abstract

Advances in antiretroviral therapy (ART) have normalized the life expectancy of people living with HIV (PLWH) but have been linked to a premature presentation of age-related comorbidities, including cancer. Telomere length (TL) is a marker of cellular aging and was investigated in blood leukocytes from 78 PLWH on ART, compared with 163 HIV-uninfected controls. The PLWH group was stratified into three subgroups: HIV-only (n = 57), HIV with AIDS-defining cancer (ADC, n = 9), and HIV with NADC (n = 12). Quantitative p [...]

421 980

Open Access Research Article

Correlation between the Storage Pattern of Spent Fuel Casks and the Neutron Multiplication Factor

Received: 21 April 2025;  Published: 19 December 2025;  doi: 10.21926/jept.2504018

Abstract

The effective neutron multiplication factor (keff) of a fissile system is a function of space and time f(x, y, z, t), where (x, y, z) are the coordinates of the reference point in space, and t is time. The evidence of the time-dependence of the neutron multiplication factor of a fissile system was published in 2017. The spatial dependence is as important as the time dependence, as interacting arrays of fissile material during storage can lead to an increase in the system (keff). Therefore, evaluation of how the sto [...]

417 1554

Open Access Original Research

Chemical Composition, Antioxidant Properties, and Nutritional Value of Diospyros kaki L. as a Potential Functional Food

Received: 10 November 2025;  Published: 12 February 2026;  doi: 10.21926/obm.icm.2601008

Abstract

Persimmon (Diospyros kaki L.) is increasingly recognized as a nutrient-dense fruit rich in health-promoting compounds. This study aimed to comprehensively evaluate the nutritional composition, phenolic profile, antioxidant potential, and elemental content of D. kaki fruit and its contribution to dietary mineral intake. Proximate analysis revealed a high moisture content, low fat, and appreciable fiber and carbohydrate levels, supporting its classification as a low-calorie, fiber-rich food. Methanolic extracts exhib [...]

411 1142

Open Access Editorial

Acupuncture’s Effects on Intracranial Pressure: From Early Observations to Modern Insights

Received: 04 January 2026;  Published: 06 January 2026;  doi: 10.21926/obm.icm.2601003

Abstract

Understanding whether acupuncture can influence intracranial pressure (ICP) and cerebral hemodynamics remains a relevant and insufficiently explored question in contemporary neurovascular research. This editorial synthesizes early experimental observations with recent clinical and technological advances to reassess the cerebral effects of acupuncture from a modern perspective. Evidence from clinical studies indicates that acupuncture can alter cerebral blood flow velocity and regional perfusion, suggesting an inter [...]

411 1125

Open Access Original Research

The Value of Camellia sinensis in the Management of Toxicity Induced by Cancer Treatments

Received: 17 June 2025;  Published: 02 December 2025;  doi: 10.21926/obm.icm.2504052

Abstract

While radiotherapy is one of the main treatments for head and neck cancer, adverse effects limit its effectiveness and affect patients' quality of life. Although various radioprotective substances have been proposed, comprehensive strategies are needed to modulate radiotoxicity. In this regard, compounds from green tea (Camellia sinensis), with antioxidant, anti-inflammatory, and antiproliferative properties, could be suitable for optimizing the radiotherapy relationship. A descriptive, prospective study was conduc [...]

397 1447

Open Access Editorial

Acknowledgment to Reviewers of OBM Neurobiology in 2025

Received: 04 January 2026;  Published: 04 January 2026;  doi: 10.21926/obm.neurobiol.2601317

Abstract

The editors of OBM Neurobiology would like to express their sincere gratitude to the following reviewers for assessing manuscripts in 2025. We greatly appreciate the contribution of expert reviewers, which is crucial to the journal's editorial process. We aim to recognize reviewer contributions through several mechanisms, of which the annual publication of reviewer names is one. Reviewers can download a certificate of recognition directly from our submission system. Additionally, reviewers can sign up to the Web of [...]

394 974

Open Access Original Research

Psychological Flexibility in Borderline Personality Disorder: A Comparative Study with Healthy Controls

Received: 09 March 2025;  Published: 31 December 2025;  doi: 10.21926/obm.neurobiol.2504316

Abstract

This study aimed to examine the psychological flexibility of individuals diagnosed with borderline personality disorder (BPD) compared to healthy controls. Psychological flexibility is a key construct related to mental health and adaptive functioning, and understanding its levels in BPD can provide insight into symptom severity and treatment outcomes. The study included 58 individuals diagnosed with BPD and 62 healthy volunteer controls, all meeting specific inclusion and exclusion criteria. Participants completed [...]

393 1455

Open Access Original Research

Sexuality in Older Adults Receiving Palliative Care: A Fundamental Dimension through the End of Life

Received: 08 October 2025;  Published: 11 February 2026;  doi: 10.21926/obm.geriatr.2601335

Abstract

The sexuality of older adults at advanced stages of illness, or at the end of life, remains a taboo topic that is rarely addressed in the literature and in practice. As a result, the knowledge base informing the support needs of older adults at the final stages of life with regards to sexuality remains scant. The present study seeks to explore experiences of sexuality in older adults with serious illness or receiving palliative care, focusing specifically on the place of sexuality in their lives, the forms of sexua [...]

382 1080

Open Access Editorial

Acknowledgment to Reviewers of OBM Integrative and Complementary Medicine in 2025

Received: 04 January 2026;  Published: 04 January 2026;  doi: 10.21926/obm.icm.2601002

Abstract

The editors of OBM Integrative and Complementary Medicine would like to express their sincere gratitude to the following reviewers for assessing manuscripts in 2025. We greatly appreciate the contribution of expert reviewers, which is crucial to the journal's editorial process. We aim to recognize reviewer contributions through several mechanisms, of which the annual publication of reviewer names is one. Reviewers can download a certificate of recognition directly from our submission system. Additionally, reviewers [...]

374 931

Open Access Editorial

Acknowledgment to Reviewers of Recent Progress in Materials in 2025

Received: 04 January 2026;  Published: 04 January 2026;  doi: 10.21926/rpm.2601001

Abstract

The editors of Recent Progress in Materials would like to express their sincere gratitude to the following reviewers for assessing manuscripts in 2025. We greatly appreciate the contribution of expert reviewers, which is crucial to the journal's editorial process. We aim to recognize reviewer contributions through several mechanisms, of which the annual publication of reviewer names is one. Reviewers can download a certificate of recognition directly from our submission system. Additionally, reviewers can sign up t [...]

370 891

Open Access Editorial

Acknowledgment to Reviewers of OBM Genetics in 2025

Received: 04 January 2026;  Published: 04 January 2026;  doi: 10.21926/obm.genet.2601322

Abstract

The editors of OBM Genetics would like to express their sincere gratitude to the following reviewers for assessing manuscripts in 2025. We greatly appreciate the contribution of expert reviewers, which is crucial to the journal's editorial process. We aim to recognize reviewer contributions through several mechanisms, of which the annual publication of reviewer names is one. Reviewers can download a certificate of recognition directly from our submission system. Additionally, reviewers can sign up to the Web of Sci [...]

364 913

Open Access Review

Novel Therapies for the Treatment of Antibody Mediated Rejection in Solid Organ Transplantation: A Systematic Review

Received: 29 October 2025;  Published: 24 February 2026;  doi: 10.21926/obm.transplant.2601267

Abstract

Antibody mediated rejection (AMR) is a considerable cause of late allograft failure in solid organ transplantation. Conventional approaches, using plasmapheresis, intravenous immunoglobulin, rituximab, bortezomib, and eculizumab have been unsuccessful in improving graft survival. This review aims to assess emerging therapies for AMR treatment across all organs. Using a PubMed search, literature published up to July 20, 2025 regarding tocilizumab, clazakizumab, carfilzomib, daratumumab, imlifidase, felzartamab, and [...]

355 1438

Open Access Original Research

Evidence for an Impact of Super Skills for Life on Emotional and Behavioral Difficulties in Greek Anxious Children

Received: 23 September 2025;  Published: 22 January 2026;  doi: 10.21926/obm.neurobiol.2601319

Abstract

Super Skills for Life (SSL) is a transdiagnostic psychoeducational program designed for children with anxiety and depressive symptoms based on cognitive-behavioral therapy. Empirically documented studies to date have demonstrated its immediate and long-term effectiveness in different contexts. The aim of this study was to assess the efficacy of the SSL program to reduce emotional and behavioral difficulties in a clinical sample of Greek-speaking primary school children aged 6 to 12. The program was implemented over [...]

348 1214

Open Access Editorial

Acknowledgment to Reviewers of Recent Progress in Nutrition in 2025

Received: 04 January 2026;  Published: 04 January 2026;  doi: 10.21926/rpn.2601001

Abstract

The editors of Recent Progress in Nutrition would like to express their sincere gratitude to the following reviewers for assessing manuscripts in 2025. We greatly appreciate the contribution of expert reviewers, which is crucial to the journal's editorial process. We aim to recognize reviewer contributions through several mechanisms, of which the annual publication of reviewer names is one. Reviewers can download a certificate of recognition directly from our submission system. Additionally, reviewers can sign up t [...]

346 839

Open Access Original Research

Quasi-Solid-State Electrolytes of Polyethylene Oxide-Based Composite Electrolyte with Liquid Electrolytes

Received: 18 November 2025;  Published: 26 February 2026;  doi: 10.21926/jept.2601004

Abstract

A thin film of PEO18Li(CF3SO2)2N(LiTFSI)-tetraethylene glycol dimethyl ether (G4)-Li1.4Al0.4Ge0.2Ti1.4(PO4)3-LiCl·H2O (LAGTP·LiCl) was prepared by addition of 1,2-dimethoxyethane (DME). The grain boundary resistance of PEO18LiTFSI-LAGTP·LiCl was considerably reduced by the addition of G4, and a large-sized thin film of the composite polymer electrolyte was prepared easily by the addition of 10 wt.% DME. The electrical conductivity of [(PEO18LiTFSI-2G4)-5 wt.% LAGTP·LiCl]-10 wt.% DME was 1.2 × 10-4 S cm-1 at 25°C, a [...]

344 878

Open Access Review

Balancing Preservation and Maximizing Utilization: A DCD Lung Procurement Strategy During Abdominal Normothermic Regional Perfusion

Received: 30 June 2025;  Published: 22 January 2026;  doi: 10.21926/obm.transplant.2601265

Abstract

The increasing demand for organ transplantation has necessitated innovative strategies to maximize donor organ utilization, especially in donation after circulatory death (DCD) contexts. This article explores the integration of direct lung recovery with abdominal normothermic regional perfusion (A-NRP) to optimize organ preservation and expand the donor pool. A-NRP effectively mitigates warm ischemic injury, supporting the viability of both abdominal and thoracic organs. Our approach emphasizes meticulous surgical [...]

340 1283

Open Access Research Article

Transformational Spaces: An Interpretative Phenomenological Inquiry into the Lived Experience of Young People Visiting Kanha Shanti Vanam Meditation Center, Telangana, India

Received: 29 October 2025;  Published: 04 February 2026;  doi: 10.21926/obm.icm.2601007

Abstract

The innate desire to belong and to connect is profoundly human, yet in a world of instant communication, millions of young people increasingly feel untethered and adrift. Loneliness is the 21st century's primary health care concern across all age groups. Young people not only feel lonely and emotionally isolated, but they also describe a lack of meaningful connections and purpose. Young people lack safe spaces where they can connect with their peers, without fear of judgment, prejudice, and pressure to succeed. In [...]

339 1033

Open Access Editorial

Acknowledgment to Reviewers of Recent Progress in Science and Engineering in 2025

Received: 03 January 2026;  Published: 04 January 2026;  doi: 10.21926/rpse.2601001

Abstract

The editors of Recent Progress in Science and Engineering would like to express their sincere gratitude to the following reviewers for assessing manuscripts in 2025. We greatly appreciate the contribution of expert reviewers, which is crucial to the journal's editorial process. We aim to recognize reviewer contributions through several mechanisms, of which the annual publication of reviewer names is one. Reviewers can download a certificate of recognition directly from our submission system. Additionally, reviewers [...]

334 828

Open Access Research Article

On the Prediction of Spur Gear Maintainability in Bottling Machines based on Failure Data

Received: 27 October 2025;  Published: 02 February 2026;  doi: 10.21926/rpse.2601002

Abstract

In bottling companies, spur gears play a vital role in ensuring efficient mechanical power transmission in bottling machines. Therefore, the maintainability of spur gears in these machines is important because it directly affects the overall efficiency, productivity, and cost-effectiveness of bottling operations. The study focused on data collection for different tasks performed on a failed gear from January to December of a particular year based on task time and frequency of occurrence, which are important factors [...]

333 937

Open Access Editorial

Acknowledgment to Reviewers of OBM Transplantation in 2025

Received: 03 January 2026;  Published: 04 January 2026;  doi: 10.21926/obm.transplant.2601263

Abstract

The editors of OBM Transplantation would like to express their sincere gratitude to the following reviewers for assessing manuscripts in 2025. We greatly appreciate the contribution of expert reviewers, which is crucial to the journal's editorial process. We aim to recognize reviewer contributions through several mechanisms, of which the annual publication of reviewer names is one. Reviewers can download a certificate of recognition directly from our submission system. Additionally, reviewers can sign up to the Web [...]

326 878

Open Access Editorial

Nutrition and Transplant Outcomes

Received: 27 January 2026;  Published: 12 February 2026;  doi: 10.21926/obm.transplant.2601266

Abstract

Dietary guidelines and Nutrient Reference Intakes are important tools for maintaining optimal health in the general population. Similar guidelines have also been developed by specific organ health associations to help their patient populations recover from disorders or prevent/delay clinical events and subsequent complications. However, there are no specific national and international guidelines to provide dietary and nutrient intake recommendations peri-transplantation. The complex nature of transplantation and in [...]

298 721

Open Access Original Research

The Impact of Governmental and Workplace Measures on the Employment Sustainability of Chronically Ill Individuals

Received: 03 November 2025;  Published: 12 February 2026;  doi: 10.21926/obm.neurobiol.2601324

Abstract

Using a two-stage qualitative design (Stage 1: expert interviews; Stage 2: biographical interviews with people with MS), existing governmental and organizational support measures for maintaining the work capacity of individuals with multiple sclerosis (MS) were analyzed, and proposals for improvement were developed. Additional state support measures were proposed, including relaxing the criteria for state assistance, creating a centralized contact point for MS-specific inquiries, and enhancing collaboration between [...]

275 726

Open Access Review

Migraine Surgery: Assessment of the Prevalence and Surgical Outcomes of Different Trigger Sites

Received: 14 November 2025;  Published: 28 February 2026;  doi: 10.21926/obm.neurobiol.2601327

Abstract

Migraine surgery is primarily indicated for patients with chronic migraine who are refractory to conventional pharmacological treatments. The procedure aims to deactivate peripheral trigger sites—anatomical zones where migraines can be triggered by nerve compression and irritation. The most common trigger areas are the frontal, occipital, and temporal. This review seeks to analyse the prevalence of treatment and corresponding success rates for these three main trigger sites. A systematic review was conducted on Pub [...]

249 808

Open Access Original Research

Aversion But Not Aggression: Emotional Traits of KM Rats in Sociability Tests

Received: 28 September 2025;  Published: 25 February 2026;  doi: 10.21926/obm.neurobiol.2601326

Abstract

The inbred Krushinsky-Molodkina (KM) rat strain, characterized by latent genetic epilepsy, reduced social motivation, and a high propensity for freezing, is a promising model for translational research of social deficits in autism spectrum disorder (ASD). In clinical practice, social deficits often lead to social withdrawal and can be accompanied by aggression. It was unknown if KM rats exhibit such aggression during inescapable social encounters. We assessed intraspecific aggression in KM and control rats using th [...]

245 727

Open Access Research Article

Modelling and Optimisation of Integrated Renewable Energy Conversion Technologies with Dual Energy Storage for an Island

Received: 17 September 2025;  Published: 09 March 2026;  doi: 10.21926/jept.2601005

Abstract

The work focused on modelling and optimisation of integrated renewable energy conversion technologies based on sunlight, wind, and biomass, with dual energy storage (battery and hydrogen), for Patani Island, Delta State, Nigeria. The study was aimed at satisfying the energy demand of the Patani Island community (5°13’43” N, 6°11’29” E). A mathematical model was developed to describe the integrated system, and a genetic algorithm was employed to optimize the allocation of energy demand, energy generation, and energy [...]

235 706

Open Access Original Research

End-of-Life Care Disparities in Older Adults with Schizophrenia Spectrum Disorders

Received: 14 October 2025;  Published: 10 March 2026;  doi: 10.21926/obm.geriatr.2601336

Abstract

Schizophrenia spectrum disorders (SSDs) are complex conditions with chronic symptoms and impairments associated with greater risk for physical comorbidity and early mortality. Understanding end-of-life care in older adults with SSDs is crucial for improving geriatric psychiatric care and identifying healthcare disparities. A cohort of 254 older adult decedents with a history of schizophrenia or schizoaffective disorder was identified using the Rochester Epidemiology Project. A control group of 254 older adult deced [...]

234 685

Open Access Original Research

Investigating Interfacial Thermal Resistance and Effective Thermal Conductivity in Epoxidized Natural Rubber Composites

Received: 14 January 2026;  Published: 09 March 2026;  doi: 10.21926/rpse.2601003

Abstract

Effective thermal management in polymeric materials still represents a considerable challenge for emerging applications, such as wearable electronics, soft robotics, and sustainable composite systems, wherein flexibility and environmental compatibility are of utmost importance. This research utilizes non-equilibrium molecular dynamics (NEMD) simulations to examine interfacial thermal resistance (ITR) and effective thermal conductivity (keff) in bio-based PBS-ENR-PBS trilayer systems. Two varieties of epoxidized nat [...]

234 1107

Open Access Review

Insights from Stem Cell and CRISPR-Based Therapies for Diabetes Mellitus: A Systematic Review

Received: 27 November 2025;  Published: 17 March 2026;  doi: 10.21926/obm.genet.2601329

Abstract

Diabetes mellitus (DM) is a metabolic disorder resulting from aberrations in insulin secretion or action. Diabetes mellitus still presents as a global health challenge. Conventional diabetes treatment may result in unwanted side effects and/or poor compliance. More personalized and curative approaches to the treatment of DM are required. The review explores recent developments in the fields of genetic and molecular underpinnings of DM, focusing on the revolutionary potential of cell- and Clustered Regularly Intersp [...]

221 950

Open Access Review

Integrated Evaluation of Electric Submersible Pump Failures under Diverse Field Operating Conditions

Received: 09 September 2024;  Published: 26 March 2026;  doi: 10.21926/jept.2601006

Abstract

Electrical submersible pumps (ESPs) are an efficient and reliable artificial lift method for lifting large volumes of fluids from wellbores at flexible rates. Despite their advantages, including high flow rates and real-time downhole telemetry, ESPs are prone to frequent and unforeseen failures under harsh reservoir conditions, resulting in costly production delays and interventions. This paper presents an integrated evaluation of ESP failure mechanisms based on an analysis of run and pull reports, dismantle inspec [...]

212 440

Open Access Original Research

Image Generation Inspired by Electroencephalography for Neuromarketing Applications Using Extracted Features from Transformer-Based Models

Received: 25 September 2025;  Published: 10 March 2026;  doi: 10.21926/obm.neurobiol.2601328

Abstract

The design of products in Neuromarketing using machine learning methods has been a continuous challenge in Computer-aided design. Previously, deep learning techniques have been applied to generate random images for domains such as furniture, fashion, and product design. However, using deep generative methods requires a large amount of data and overlooks human aspects in the design process. This paper aims to extract human perceptual factors from brain signals using a Transformer-based model and involve them in arti [...]

206 675

Open Access Original Research

Examining the Pre-Hospital Workflow of Stroke Patients Referred with Code SAMA (724) and their Outcome in the Emergency Department of Imam Reza Hospital (AS)

Received: 22 February 2025;  Published: 25 February 2026;  doi: 10.21926/obm.neurobiol.2601325

Abstract

The "Sama Code" is a protocol implemented in Iranian pre-hospital emergency services to manage time and treat patients with suspected stroke symptoms based on the FAST criteria. This study aims to analyze the workflow of patients with stroke symptoms transferred under the Sama Code. All patients with neurological symptoms who were brought to Imam Reza Hospital by pre-hospital emergency services after activating the Sama Code during the years 2021 and 2022 were included in the study. Data were collected from pre-hos [...]

184 617

Open Access Review

Unraveling the Role of Non-Coding Genetic Variants in Male Infertility: Insights from the Chinese Population

Received: 03 December 2025;  Published: 09 March 2026;  doi: 10.21926/obm.genet.2601327

Abstract

Male infertility is a growing concern worldwide, with almost half of infertility cases being male, and the trend is rising in China as a result of multifaceted genetics-environment interaction. Important breakthroughs have been made in identifying mutations in annotated protein-coding genes associated with male infertility. However, a significant part of the human genome, namely non-coding DNA, has not yet been explored. Recent breakthroughs in the realm of high-throughput genomic technologies have unveiled the ind [...]

172 658

Open Access Research Article

Embodied Rituals and Healing Practices in Turkish Health Culture: Implications for Contemporary Healthcare Environments

Received: 14 October 2025;  Published: 02 March 2026;  doi: 10.21926/obm.icm.2601010

Abstract

Throughout human history, movement has functioned not only as a physical activity but also as a ritual, considered a healing practice linked to meaning-making and social balance. Bodily performances and ritual-based practices—such as folk dances and mystical rituals—have historically supported the physical and emotional integrity of individuals. This paper examines the historical continuity of movement-based performative practices in Turkish health culture through religious and mystical rituals, folk dances, and mu [...]

164 713

Open Access Review

Challenges and Ethical Issues Related to Non-Invasive Prenatal Testing (NIPT)

Received: 21 January 2026;  Published: 26 March 2026;  doi: 10.21926/obm.genet.2601332

Abstract

Non-invasive prenatal testing (NIPT) is now standard in prenatal care in many countries, even though it was introduced only about 15 years ago. Due to its rapid adoption into decades-old prenatal care plans, gynecologists, obstetricians, and the general public still struggle to understand the possibilities, benefits, and limitations of NIPT. The biggest challenge facing NIPT is that comprehensive training for healthcare professionals and independent, unbiased information for pregnant women and their families about [...]

160 561

Open Access Research Article

“Make Sure That Our Culture and Color is Known:” Maternal Perceptions of Using Media in the Ethnic-Racial Socialization of Young Black Children

Received: 10 October 2025;  Published: 13 March 2026;  doi: 10.21926/obm.icm.2601011

Abstract

Although methods of ethnic-racial socialization have been studied in the past, welcoming in a new digital age has affected how parents engage with their children on topics such as race and culture. While media can be an engaging way to expose young children to race and culture, the underrepresentation of Black youth in media in the United States has posed a dilemma for Black parents about the best way of using media to socialize their young children. To understand how Black mothers expose their children to ideas ab [...]

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Open Access Original Research

A New Model for the Shear of Atomic Planes

Received: 21 December 2025;  Published: 18 March 2026;  doi: 10.21926/rpm.2601002

Abstract

The article presents a model that describes the shear of atomic planes in crystalline solids by accounting for their electronic structure. Previous studies have shown that an isotropic distribution of valence electrons leads to a spherically symmetric interatomic potential, which affects the stability of the crystal lattice against small shear deformations. Under these conditions, lattice stability is largely determined by the crystal's surface layer. As a consequence, the resistance to atomic-plane shear exhibits [...]

133 402

Open Access Original Research

Determining the Role of KRAS in Patients with Different Demographic Profiles Diagnosed with Diabetes Mellitus: A Case-Control Study

Received: 06 December 2025;  Published: 15 March 2026;  doi: 10.21926/obm.genet.2601328

Abstract

Diabetes mellitus (DM) is widely spread among populations. About 3 of 10 people show the symptoms of this disease. Many factors may cause this illness in both types (type 1 and type 2 DM), mainly attributed to insufficient insulin production in type 1 DM or developing insulin resistance in type 2 DM. Genes that control specific biochemical pathways involving glucose metabolism can interfere with the manifestation of this disease when they undergo genetic changes like KRAS. Investigating the role of KRAS in DM. Abou [...]

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