by Remedios Martinez-Guijarro  , Maria Pachés  , Inmaculada Romero  and Daniel Aguado

Received: 08 October 2021;  Published: 15 December 2021;  doi: 10.21926/aeer.2104033

Heavy metal(loid)s are a group of elements present commonly in the environment, including Cr, Ni, Cu, Zn, Cd, Hg, Pb, and As elements, among others. While these elements could have their origins in natural sources, anthropogenic activities, such as mining, agriculture, industry, etc., are also responsible for enhancing the concentration of these elements in the ecosystems up to undesirable levels. A few of these metal(loid)s serve as necessary micronutrients for life, while the others are extremely harmful and migh [...]

by Joshua A Vova

Received: 21 February 2022;  Published: 20 April 2022;  doi: 10.21926/obm.neurobiol.2202120

Cerebral Palsy (CP) is the most frequent cause of childhood disability. CP occurs in 1 out of every 345 children in the United States. CP is primarily a motor disease that is the result of an insult to the brain that occurs during the prenatal or early postnatal period when the brain is still developing. CP is not a single disease but a physical description of motor impairments that originate from multiple etiologies. This article briefly discusses the etiologies, classification and management of the neurologic med [...]

by Garuth Chalfont  , Jane Simpson  , Sarah Davies  , David Morris  , Ruth Wilde  , Leigh Willoughby  and Christine Milligan

Received: 08 April 2019;  Published: 07 August 2019;  doi: 10.21926/obm.geriatr.1903066

The dominant narrative around dementia argues that progression cannot be halted or reversed. However, evidence on multimodal non-pharmacological treatments formulated around a ‘personalised medicine’ approach challenges this view. This paper reviews the current evidence for dementia prevention utilising such treatments and explains the logic of applying personalised medicine. The functional medicine treatment approach to ‘root cause’ analysis is presented as currently practiced with patients experiencing cognitive [...]

by Richard B. Kreider

Received: 01 April 2021;  Published: 03 November 2021;  doi: 10.21926/obm.icm.2104041

Obesity has historically been thought to simply be related to an imbalance between energy intake and expenditure. Weight loss recommendations have traditionally focused on reducing energy intake, maintaining either a high-carbohydrate low-fat diet or vice versa, and increasing physical activity typically through low to moderate intensity exercise. More recently, genetic, physiological, and behavioral factors have also been found to play a significant role in the etiology of obesity. For this reason, the prevention [...]

by Babak Jahani  , Xinnan Wang  and Amanda Brooks

Received: 26 June 2020;  Published: 08 September 2020;  doi: 10.21926/rpm.2003021

Bone tissue engineering (BTE) as a modern and more effective treatment for bone defects has recently received lots of attention. One of the pivotal parts of BTE is the “scaffold”, which functions as an indwelling carrier of cells and additives, as well as, providing a foundation for cell growth and eventually forming new, native-like bone. Up to now, many methods and materials have been employed to manufacture bone scaffolds. This review focuses on providing both basic knowledge of BTE as well as possible methods o [...]

by Maurizio Arena  and Claudia Aprea

Received: 16 December 2020;  Published: 22 February 2021;  doi: 10.21926/aeer.2101002

The current situation of the COVID-19 pandemic has led to multiple changes in the international market as well as in the lifestyle of people worldwide. The transport sector has undoubtedly been one of the most affected sectors due to restrictions imposed by the governments across the world to protect the health of their citizens, particularly the restrictions imposed on the operation of airlines. On the other hand, the reduction in travel by means of transport has contributed in part to the improvement in the envir [...]

by Kenneth Ugoeze  , Christian Alalor  , Chidozie Ibezim  , Bruno Chinko  , Peter Owonaro  , Clement Anie  , Ngozi Okoronkwo  , Amaka Mgbahurike  , Chijioke Ofomata  , Deghinmotei Alfred-Ugbenbo  and Geraldine Ndukwu

Received: 22 September 2023;  Published: 22 January 2024;  doi: 10.21926/aeer.2401005

The discovery of antibiotics and their use in the last century substantially shifted the management of an array of infections. However, its unprecedented irrational usage and inept disposal of their waste exposed the ecosystems to unquantifiable antibiotic deposits, triggering the emergence of antimicrobial resistance (AMR) with its immeasurable critical risk to public health. By adopting a narrative review method and accessing the available literature, the authors described what constitutes antibiotic waste, their [...]

by Nikolai A. Zarkevich

Received: 30 September 2019;  Published: 06 January 2020;  doi: 10.21926/jept.2001001

Most power plants produce electricity by converting a mechanical motion into alternating current (AC). Photovoltaic solar panels convert an electromagnetic flux of light into direct current (DC). In general, electric energy can be harvested from a flux in the environment or from a change of the environment itself. One can produce electricity from mechanical, chemical, thermal, electromagnetic (light), or another physical flux, or from a change of temperature, chemical composition, or a physical field: gravitationa [...]

by Peta Stapleton  , Trude Roos  , Glenn Mackintosh  , Emma Sparenburg  , Debbie Sabot  and Brett Carter

Received: 14 October 2019;  Published: 17 December 2019;  doi: 10.21926/obm.icm.1904065

Background: The combination of dietary restraint and physical exercise as a recommended treatment for weight loss has had limited long-term success. One factor proposed as limiting weight management techniques efficacy is the failure to target psychological processes linked with overeating. Consistent with prior research that has identified the efficacy of emotional freedom techniques (EFT) in reducing food cravings and aiding weight loss, this pilot randomised controlled trial (RCT) examined the impact of online d [...]

by Wisut Chamsa-ard  , Derek Fawcett  , Chun Che Fung  and Gerrard Poinern

Received: 28 September 2020;  Published: 29 December 2020;  doi: 10.21926/jept.2004018

The demand for high-quality freshwater is increasing due to global population growth, intensifying agricultural practices and expanding industrial development. Additionally, many global regions have low levels of rainfall which makes them arid and incapable of supporting large human populations or agriculture. Currently, large quantities of fossil fuels are used to generate the power needed to drive energy intensive desalination processes that deliver high-quality freshwater to many of these regions. However, the u [...]

by Trevor R Norman

Received: 07 February 2021;  Published: 14 October 2021;  doi: 10.21926/obm.neurobiol.2104108

Depression in the elderly is a significant clinical problem which is likely to endure as an ongoing issue as the cohort of individuals aged over 65years continues to increase as a proportion of the total population. While there are a multiplicity of approaches to the treatment of depression, the mainstay for moderate to severe cases is pharmacotherapy. The majority of extant antidepressants have demonstrated efficacy, at least in short term (6-12weeks) clinical evaluations. There is demonstrable efficacy over and a [...]

by David Smithard  , Signe Westmark  and Dorte Melgaard

Received: 15 September 2019;  Published: 15 November 2019;  doi: 10.21926/obm.geriatr.1904086

Background: With the increasing age of the world population, the number of old and frail people is increasing. Respiratory disease is a common reason for hospital admission for older people. Aspiration of saliva, which is probably infected, is the likely etiological agent. The incidence of an abnormal swallow is high in frail older people. Despite the high incidence of swallow problems among older people, many hospital services do not routinely screen older people for dysphagia. Methods: A survey, using Research El [...]

by Dorothy S Greene

Received: 17 July 2021;  Published: 16 November 2021;  doi: 10.21926/obm.icm.2104047

Yoga is increasingly becoming a strategy for wellness in the United States. A 2016 survey found that nearly 37 million Americans practice yoga and an additional 12 million say they intend to try it in the coming year. Yoga is also being studied as an intervention for a number of physical and behavioral health disorders. This short report examines yoga’s utility as a treatment or adjunctive tool for addiction recovery. Because addiction is characterized as a biopsychosocial-spiritual disorder and yoga is a holistic [...]

by Takahiro Fujimoto  , Hidetake Kobayashi  , Takeshi Hataoka  , Kazuo Taniguchi  and Keisuke Miura

Received: 17 May 2020;  Published: 09 December 2020;  doi: 10.21926/obm.icm.2004045

Obesity causes serious long-term health problems in people worldwide. Since the effect of dietary advice is possibly limited, weight loss can be a major challenge; therefore, additional weight control techniques may be beneficial. We conducted four experiments to evaluate if auricular acupuncture point stimulation with simple metal beads (AA) rather than the popular use of intradermal needle (DA) to stimulate auricle would support weight loss. In this retrospective study, weight change in Japanese women (aged 18 to [...]

by Carrie Reedy  , Siobhan Huggins  and Leslyn Keith

Received: 31 May 2025;  Published: 03 September 2025;  doi: 10.21926/rpn.2503019

Lipedema is a chronic, often misdiagnosed disease characterized by painful, disproportionate fat accumulation in the extremities. Commonly mistaken for obesity or lymphedema, lipedema primarily affects women and has long been thought to be resistant to dietary intervention, a belief originating from its initial description by Allen and Hines at the Mayo Clinic in 1940. However, emerging research challenges this notion, revealing that individuals with lipedema often respond positively to therapeutic carbohydrate (CH [...]

by Krish Chetty

Received: 02 March 2023;  Published: 25 July 2023;  doi: 10.21926/obm.geriatr.2303243

This study delves into the potential benefits of Artificial Intelligence (AI) literacy training for late-career-stage workers approaching retirement. These workers often possess extensive experience but may lack the necessary digital and AI skills. AI literacy training can empower them to leverage their experience and become proficient contributors to the digital economy. Furthermore, the article describes how these workers might benefit from AI training, particularly when employing practical applications of AI in [...]

by Gabriel Moss  , Gi-Ming Wang  , Bethanny Bristol  , Hasina Momotaz  , Ming Li  and Richard T. Lee

Received: 05 May 2022;  Published: 04 August 2022;  doi: 10.21926/obm.icm.2203033

Reiki is a form of energy healing that has gained popularity in the United States, but there remains skepticism about its scientific validity. This study examines the ability of Reiki practitioners (RP) to detect human energy fields (HEF). Volunteer RP were asked to identify the location of a human hand under blinded conditions for a total of 20 trials. Four potential options existed for subjects (right, left, both, or neither); thus, random chance would predict a success rate of 25%. A success rate of >40% was [...]

by Naoki Ohkura  , Gen-ichi Atsumi  , Seima Uehara  , Mitsuhiro Ohta  and Masahiko Taniguchi

Received: 18 July 2018;  Published: 23 January 2019;  doi: 10.21926/obm.icm.1901005

Metabolic syndrome is a serious health condition comprising a combination of glucose metabolism disorder, high blood pressure and obesity. The main underlying risk factors for metabolic syndrome are abdominal obesity and insulin resistance. Various studies have shown that herbal medicines can effectively reduce the risk of developing metabolic syndrome. Angelica keiskei Koidzumi (ashitaba), a large perennial herb native to the Southeast Pacific coast of Japan, has recently become a popular herbal medicine, dietary [...]

by Ju dong Lee  , Jinho Kim  and Seungjoo Lee

Received: 29 September 2022;  Published: 16 January 2023;  doi: 10.21926/rpm.2301007

Most spent coffee grounds (SCGs), a byproduct of brewing coffee, are buried in landfill sites, and their decomposition produces significant greenhouse gases. As the recent warming of the Earth’s climate has made it imperative that industries reduce greenhouse gas emissions, the present study investigates the viability of recycling SCGs for use as a partial replacement of aggregates in concrete materials. Cement mortar samples with a fixed cement-to-water ratio and varying amounts of SCGs were fabricated and tested. [...]

by Che Mohd Nasril Che Mohd Nassir  , Hafizah Abdul Hamid  , Aqilah Hambali  , Nizar Abd Manan  , Muhammad Zulfadli Mehat  , Nurul Iman Ismail  and Muzaimi Mustapha

Received: 31 July 2022;  Published: 14 November 2022;  doi: 10.21926/obm.neurobiol.2204144

The nectar produced by bees in nature is known as honey and has been consumed for its nutritional and medicinal properties. There is growing evidence that honey and its compounds have anti-inflammatory, antioxidant and anti-microbial properties that are relevant to the maintenance of health and the prevention of illnesses, including cardiocerebrovascular disease. Cerebral small vessel disease (CSVD) is one of the major risk factors for diseases such as stroke, dementia, Alzheimer’s disease, and Parkinson’s disease. [...]

by Gila Chen

Received: 04 March 2019;  Published: 24 April 2019;  doi: 10.21926/obm.icm.1902026

Background: A large body of empirical evidence has supported the notion that individuals with substance use disorders (SUDs) have difficulty regulating their negative emotions and employing emotion-regulation strategies. The aim of this article is to (a) explore the role of self-compassion in providing an emotion-regulation strategy for initiating a process of recovery from SUDs; (b) examine the role of self-compassion in building recovery capital (RC) to promote long-term recovery; and (c) examine the practice of [...]

by Kyunga Kim  , Shlomit Kenigsberg  , Andrea Jurisicova  and Yaakov Bentov

Received: 01 January 2019;  Published: 29 March 2019;  doi: 10.21926/obm.genet.1901070

The mitochondria of the oocyte are a prominent source of energy metabolism as well as mitochondrial DNA that will later populate the cells of the offspring. Recent discoveries provided new insight into the physiology of the mitochondria and its unique genetics. The concept of heteroplasmy defined as the presence of more than one type of mitochondrial genome, is gaining increasing recognition as an important contributor to several complex morbidities, age-related reproductive dysfunction and aging. Understanding the [...]

by Kai-Yang Liu  , Li-Xia Yin  , Xu Lin  and Shun-Xing Liang

Received: 20 March 2022;  Published: 21 April 2022;  doi: 10.21926/rpm.2202008

Biomaterials have always been the focus of material scientists and engineers. Titanium and its alloys have favorable properties, such as high strength, low density, good corrosion resistance, non-toxicity, low elastic modulus, biocompatibility, etc. Thus, Ti alloys have received much attention from scientists and engineers who work with biomaterials. Among these properties, the elastic modulus is a very important property for implant biomaterials because it avoids the “stress shielding” effect. In this study, we su [...]

by Milky Mittal  , Annu Kumari  , Bhashkar Paul  , Adya Varshney  , Bhavya  , Ashok Saini  , Chaitenya Verma  and Indra Mani

Received: 07 October 2023;  Published: 04 March 2024;  doi: 10.21926/obm.genet.2401219

Gene therapy involves either the direct introduction of genetic material (DNA or RNA) into the host cell (or organ), known as in vivo gene therapy, the re-introduction of the modified target cells taken out of the host, or ex vivo gene therapy. Cancer is mainly caused by the non-functioning of genes required for normal cell proliferation, and it has emerged as the leading cause of death globally due to the absence of efficient and safe therapies as well as early diagnostic modalities. Therapeutic trials using gene [...]

by Eric A. Armour  , Angela M. Curcio  and Robert H. Fryer

Received: 04 February 2020;  Published: 28 July 2020;  doi: 10.21926/obm.neurobiol.2003068

Hypoxic-ischemic encephalopathy is a major cause of death and disability in the newborn period. Experimental models have demonstrated that brain injury in hypoxic-ischemic encephalopathy occurs in two phases: primary energy failure and secondary energy failure. In primary energy failure, there is a cessation of oxidative metabolism and irreversible neuronal injury, followed by secondary energy failure due to glutamate release, elevation of intracellular calcium, reactive oxygen species formation, apoptotic cell dea [...]