Table of Content

Open Access Review

The Potential of Chickpea (Cicer arietinum L.) for Anti-Osteoporotic Agent in Post-Menopausal Women: A Systematic Review of In Vivo Study

Received: 09 April 2024;  Published: 23 August 2024;  doi: 10.21926/rpn.2403012

Abstract

This systematic review aimed to analyze the in vivo study of the anti-osteoporotic activity of chickpeas. A comprehensive search for English language papers published between January 2013 and December 2023 using the keywords chickpea or Cicer arietinum, anti-osteoporotic activity or anti-osteoporotic effect, chickpeas and anti-osteoporotic activity, Cicer arietinum and antiosteoporotic activity and their synonyms yielded 3566 results from PubMed, ScienceDirect, SpringerLink and Google Scholar. Articles were screene [...]

1661 12354

Open Access Original Research

Role of Automated Insulin Delivery (Artificial Pancreas) in Islet Transplantation: An In Silico Assessment

Received: 17 May 2018;  Published: 11 September 2018;  doi: 10.21926/obm.transplant.1803019

Abstract

Background: Human pancreatic islet transplantation is a minimally-invasive procedure that is gaining recognition for the treatment of type 1 diabetes (T1D). Selected patients with unstable T1D, hypoglycemia unawareness, history of severe hypoglycemia, and glycemic lability, not successfully stabilized with intensive insulin treatment, can be offered this alternative therapy that has been shown to provide long-term glycemic control with near-normalization of hemoglobin A1c in the absence of severe hypoglycemia. Toda [...]

1607 12349

Open Access Original Research

A Mixed Methods Approach to Understanding Conceptions of Mindfulness Meditation

Received: 19 June 2018;  Published: 14 October 2018;  doi: 10.21926/obm.icm.1804026

Abstract

Background: Mindfulness meditation (MM) is an increasing area of interest for health professionals and the general public alike. Beneficial outcomes are associated with this practice; however, definitions of mindfulness and meditation are varied, and anecdotal accounts suggest that people hold conceptions about the constructs. Furthermore, mindfulness has been incorporated into therapeutic modalities without much consideration for context, including the client’s previous experiences with and understanding of MM. To [...]

2076 12341

Open Access Original Research

Acupuncture for Chemo-Related Nausea and Vomiting

Received: 29 September 2018;  Published: 28 March 2019;  doi: 10.21926/obm.icm.1901020

Abstract

Background: In recent years, complementary and alternative medicine (CAM) techniques have become very widespread; among these, acupuncture can play an important role in the treatment of adverse effects related to chemotherapy. This role has been recognized by the National Institutes of Health after many clinical studies, thus allowing the official introduction of acupuncture in supportive therapy for oncological diseases, particularly to prevent nausea and vomiting. The aim of this paper is to describe the activity [...]

2344 12340

Open Access Review

The Multifaceted Roles of Ketogenic Diets in Neurology-Brain Cancers and Other Neurologic Diseases

Received: 30 December 2021;  Published: 19 April 2023;  doi: 10.21926/rpn.2302007

Abstract

The ketogenic diet (KD) is currently well known in the lay media as a quick way to lose weight. However, the KD is not a new medical concept. The KD was used in the early 1900s to control seizures. However, as we developed more effective pharmacological agents, we used the KD less until it became practically obscure by the 1980s. Similar to the effects of fasting, the KD leads to the production of ketones as an alternative energy source to glucose. Therefore, the KD has many beneficial metabolic effects, such as an [...]

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Open Access Review

The Roles of Collagen in Islet Transplantation

Received: 02 October 2020;  Published: 27 November 2020;  doi: 10.21926/obm.transplant.2004127

Abstract

Islet transplantation is a cellular replacement therapy for severe diabetes mellitus. Although the clinical outcome of islet transplant has been improving, the transplant efficacy of this treatment is not superior to that of pancreatic organ transplantation, a similar transplant therapy. Various factors have been characterized as ‘islet transplantation specific’, which includes lack of revascularization and ischemia, innate inflammation, or autoimmunity, affect the therapeutic outcome of this treatment. Among them, [...]

2200 12330

Open Access Review

Advances in Nanocarriers for Drug Delivery in Dental Therapies

Received: 19 August 2021;  Published: 28 September 2021;  doi: 10.21926/rpm.2103039

Abstract

Dental caries are one of the major causes of oral degeneration diseases. In order to treat dental-related diseases, it is often challenging and expensive. Recent literature has reported many advances in designing delivery systems utilizing polymers and novel biomaterials. Polymers play an important role in designing many nanoformulations like liposomes, polymeric micelles, polymeric nanoparticles, carbon-based nanoparticles, nano-hydroxyapatite, iron oxide, zirconia, silica, and silver nanoparticles were used to tr [...]

1721 12327

Open Access Research Article

Modeling Tile Drainage Outflow in Thin Agricultural Soils with Impermeable under Layer in Newfoundland and Labrador, Canada

Received: 30 December 2020;  Published: 28 June 2021;  doi: 10.21926/aeer.2102016

Abstract

Subsurface tile drainage installation helps to maintain water table levels and to meet adequate crop moisture requirements. Artificial subsurface drainage continues to be a common practice in Newfoundland and Labrador (NL) and elsewhere around the world. The main objective of this study was to evaluate the performance of DRAINMOD in simulating water table depth (WTD) and water outflow from tile drained agricultural fields. This site on the Avalon Peninsula of Eastern Newfoundland has a rolling landscape with predom [...]

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Open Access Original Research

Application of the FISH Method for Analyzing Chromosome Segregation Patterns in Preimplantation Embryos from Robertsonian Translocation Carriers

Received: 28 March 2022;  Published: 22 June 2022;  doi: 10.21926/obm.genet.2202157

Abstract

Robertsonian translocations (RTs) are very common balanced structural chromosome rearrangements in humans. Due to alterations in the chromosome segregation pattern and the formation of unbalanced gametes and embryos, the carriers of RTs have a significant risk of reproductive failure. For over 30 years, fluorescent in situ hybridization (FISH) has been used for preimplantation genetic testing for chromosomal structural rearrangement (PGT-SR) in carriers of RTs. The data obtained by performing FISH for PGT-SR can be [...]

1878 12323

Open Access Original Research

Faster and More Accurate Identification of Male Faces in Female Care Home Residents

Received: 21 August 2019;  Published: 26 February 2020;  doi: 10.21926/obm.neurobiol.2001050

Abstract

We investigated whether healthy older adults who live in female-dominated old age care homes can identify the gender of male and female faces of people from different ethnicities in the same way as young adults. We hypothesized that this mainly female environment would lead by exposure to a female-gender bias. A sample of 40 participants aged 20-30 and 70-80 years identified the sex-of-face of 120 images of young and old adults, male and female faces, black and white faces, presented in a randomized sequence in a s [...]

2151 12308

Open Access Review

Aspiration Pneumonia and the Traditional Chinese Medicine Banxia Houpu Tang

Received: 24 August 2020;  Published: 27 October 2020;  doi: 10.21926/obm.geriatr.2004136

Abstract

Aspiration pneumonia is one of the most common reasons for death in stroke patients. Recently, a traditional herbal medicine banxia houpu tang is remarked to prevent the aspiration pneumonia. This review tells the history of study of banxia houpu tang for prevent aspiration pneumonia.

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Open Access Case Report

The Use of ECMO in Treatment of Post Liver Transplant Septic Shock

Received: 28 May 2020;  Published: 17 August 2020;  doi: 10.21926/obm.transplant.2003116

Abstract

Liver transplant is a life-saving therapy for patients with end stage liver disease and liver cancer. Liver re-transplantation cases are usually more challenging and riskier than primary surgery, they require careful consideration and larger recourse utilization. Decision making on who receives transplantation surgery includes individual patient risks and benefits, physician judgment, specific transplant center policies, surgical experience, geographic organ availability, and ethical considerations. Several mathema [...]

1992 12304

Open Access Comment

Compassion in a Doctor-Patient Relationship: Objectively Measuring Compassionate Behavior Using the Emotional Availability (EA) Scales

Received: 13 March 2019;  Published: 25 July 2019;  doi: 10.21926/obm.icm.1903048

Abstract

Most research on compassion utilizes self-report measures. Subjective report of the individual can provide an authentic window about compassion toward the self. Compassionate behavior toward another person, on the other hand, can and should be measured more objectively than self-report allows. Compassionate behavior toward another can best be measured by how that individual actually interacts with others. In this essay, we will describe how behavior that is compassionate can be objectively measured, and one that ha [...]

2222 12302

Open Access Original Research

Zinc Silicate Thin Film Composites Obtained by a Sputtering Based Approach: Structural, Dielectric and Photovoltaic Properties

Received: 19 January 2021;  Published: 02 April 2021;  doi: 10.21926/jept.2102015

Abstract

This study deals with the production of zinc silicate thin films employing a solid-state reaction at temperatures ranging from 300 °C to 560 °C, to develop new inorganic, n-type materials with seemingly incompatible properties as low work function, high mobility, and high visible transmittance. Depending on a careful reaction control, zinc silicates can preserve reagents (silicon and/or ZnO) as nanoaggregate guests, exhibiting tunable light absorption and emission properties that make them useful for differ [...]

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Open Access Review

Genomic Biomarker Surveillance in the Care of Solid Organ Transplant Recipients: An Update for the General Clinician during the Coronavirus (CoVid-19) Pandemic

Received: 27 March 2020;  Published: 06 May 2020;  doi: 10.21926/obm.transplant.2002107

Abstract

Biomarker surveillance after solid organ transplant is an advancing field with promise for further elucidation through high-throughput analyses and “omics” technologies. To date, Gene Expression Profiling (GEP; AlloMapâ) is the only FDA-cleared genomic assay as surveillance for moderate-severe TCMR versus allograft quiescence after heart transplantation. Clinical validity and utility, however, have been recently established after kidney and heart transplantation, for analysis of donor-derived cell-free DNA in the a [...]

2131 12293

Open Access Original Research

Impact of the COVID-19 Pandemic Measures on the Number of Meals and the Types of Physical Activity of Adolescents: Cross-Sectional Study in Delhi, India

Received: 10 January 2022;  Published: 30 March 2022;  doi: 10.21926/rpn.2201010

Abstract

COVID-19 greatly affected the lives of adolescents through restrictions such as less playtime, more screen time, and limited interaction with peers. In this study, we assessed the impact of the COVID-19 pandemic on the dietary and physical activity-related behavior of school students aged 10–16 years. This cross-sectional study was conducted with adolescents recruited from seven randomly selected private schools in Delhi, India, during 2021. A self-administered web-based survey was conducted to evaluate the behavio [...]

2100 12289

Open Access Review

Newborn Screening for Inborn Errors of Metabolism

Received: 14 June 2023;  Published: 18 October 2023;  doi: 10.21926/obm.genet.2304197

Abstract

Newborn screening can now detect more than 50 disorders, providing early and often life-saving treatment. Inborn errors of metabolism account for the majority of these disorders. This review will consider the more common metabolic disorders identified on newborn screening, including history, technique and management of these disorders.

1829 12286

Open Access Review

Practical Review on the Impact of Celiac Disease on the Patient

Received: 05 August 2022;  Published: 13 February 2023;  doi: 10.21926/rpn.2301003

Abstract

Celiac disease (CD) is a multisystem immune-mediated disorder resulting in enteropathy of the small intestine with the ingestion of gluten, in genetically susceptible individuals. This condition impact 1% of the population and can result in the development of other conditions such as chronic fatigue, anemia, osteoporosis, aphthous stomatitis, elevated liver enzymes, joint pain, infertility, peripheral neuropathy, and epilepsy. In this review, we outline the clinical presentation of CD, the physiological differences [...]

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Open Access Review

Complementary Medicine and Expressive Arts Therapy: Adjuvant for Recovery Following Neurosurgical Procedures

Received: 12 October 2022;  Published: 17 January 2023;  doi: 10.21926/obm.icm.2301007

Abstract

Art as a way of healing is primordial in many cultures. Expressive Arts Therapy (ExAT) uses art, music, dance, and writing to help individuals navigate their healing journey. Patient self-expression as a mode of recovery has been observed in patients with Parkinson’s disease, epilepsy, Amyotrophic Lateral Sclerosis (ALS) and cancer. Complementary medical approaches such as acupuncture and mindfulness have also demonstrated benefits in patients suffering from neurological injury. Complementary medicine and ExAT are [...]

1900 12274

Open Access Opinion

FASD and Brain Development: Perspectives on Where We are and Where We Need to Go

Received: 14 March 2017;  Published: 23 March 2017;  doi: 10.21926/obm.neurobiol.1701002

Abstract

Maternal consumption of alcohol (ethanol) during pregnancy can lead to life-long neurobehavioral and cognitive abnormalities in the offspring, collectively referred to as Fetal Alcohol Spectrum Disorders (FASD). Prenatal exposure to ethanol is one of the leading causes of non-genetic intellectual disability and FASD is an umbrella category that includes Fetal Alcohol Syndrome, Partial Fetal Alcohol Syndrome, Alcohol Related Birth Defects, and Alcohol Related Neurodevelopmental Disorder. Children with a history of&n [...]

1701 12270

Open Access Original Research

The Effects of Subjective and Objective Sleep Monitoring on Sleep Patterns and Attitudes

Received: 22 November 2019;  Published: 11 March 2020;  doi: 10.21926/obm.neurobiol.2001052

Abstract

Self-reports and actigraphy are common methods of sleep monitoring. Portable polysomnography (p-PSG) may serve as a screening tool in natural environments. Common concerns with its use are that sleep and compliance might be affected. Further, dysfunctional beliefs of the subjects may contribute to sleep disturbances, which might manifest throughout sleep monitoring. This study examined the effect of monitoring sleep patterns and attitudes among healthy individuals. Sixty-eight physically active university students [...]

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Open Access Original Research

Dementia: Aloneness, Social and Relational Engagement, and Psychological Growth in Families

Received: 23 June 2018;  Published: 08 October 2018;  doi: 10.21926/obm.geriatr.1804013

Abstract

Background: Minimal research investigates negative and positive perspectives of wellbeing in families, when a member with dementia is limited in their speech, or speech is absent. Methods: Seeking to explore this phenomenon further, semi-structured interviews sought negative and positive subjective interpretations from 27 family carers (mild to profound dementia). Interviews explored the participants' experience of changing relational and social engagement when a family member lives with dementia. Data were analyse [...]

2170 12263

Open Access Review

Problems Associated with the Measurement of Neuropsychiatric Symptoms of Dementia

Received: 04 December 2019;  Published: 17 February 2020;  doi: 10.21926/obm.geriatr.2001106

Abstract

Neuropsychiatric symptoms (NPS) affect nearly all persons living with dementia (PLWD) at some point during the course of the disease. Given the absence of a cure or effective pharmacotherapy for dementia, it is particularly important to prevent, measure, track, and manage NPS in dementia care. Unfortunately, these efforts are hindered by inconsistent operational definitions and measurement tools for numerous neuropsychiatric symptoms. This review examines agitation, aggression, restlessness, and rejection of care a [...]

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Open Access Review

The Potential Role of Commensal Microbes in Optimizing Nutrition Care Delivery and Nutrient Metabolism

Received: 20 December 2021;  Published: 26 May 2022;  doi: 10.21926/rpn.2202014

Abstract

Microbes have been part of the diet throughout human history. In the evolution of food preservation practices, some techniques inadvertently leveraged microbial activity not only to extend the storage life but also to enhance the properties and nutritive value of foods. In the last century, a variety of bacterial species (referred to as probiotics) were found to confer health benefits to the host. The advent of high-throughput sequencing methods facilitated improved surveillance of conventional probiotics within gu [...]

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Open Access Original Research

Technical Analysis of Sawdust-to-Power: A Paradigm Shift in Waste Management in a Typical Developing Economy

Received: 01 August 2023;  Published: 08 November 2023;  doi: 10.21926/jept.2304033

Abstract

The proper management of sawdust is critical to socioeconomic development. In this research, waste-to-energy has been proposed to utilize sawdust in selected timber markets in Port Harcourt, namely, Illoabuchi Timber Market, Marine Base Timber Market, and Mile 3 Timber Market. A quantitative approach has been taken to estimate the sawdust generation, energy potential, power generation capacities, and pollutant reduction of indiscriminate combustion of sawdust. The findings suggest that, annually, 171 ktons, 42 kton [...]

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