by Loren Pickart  and Anna Margolina

Received: 20 January 2021;  Published: 06 April 2021;  doi: 10.21926/obm.genet.2102128

The human copper-binding peptide GHK-Cu is a naturally occurring small plasma tripeptide (glycyl-l-histidyl-l-lysine) with a high affinity for copper (2+). GHK-Cu has multiple biological effects. It is known to stimulate regeneration of skin, nervous tissue, bones, lungs and liver, protect liver from oxidative damage, restore activity of irradiated fibroblasts, reduce inflammation and increase levels of antioxidant enzymes. Recent studies established that GHK modulates activity of a number of genes. It has been sho [...]

by John Hanna

Received: 30 April 2023;  Published: 21 February 2024;  doi: 10.21926/rpm.2401006

The main weakest point of concrete is its exposure to cracks, and concrete structure repair is expensive, especially for infrastructure maintenance, which is difficult to access. The ability of self-healing concrete (SHC) to successfully heal fractures without the assistance of humans has received much attention since it increases operational life and lowers maintenance expenses. This paper reviews various techniques and technologies of autogenous and autonomous self-healing concrete. Much more attention is given t [...]

by Ayodeji Folorunsho Ajayi  , Oluwole Tolulope David  , Adelakun Ademola Ayodele  , Ajayi Lydia Oluwatoyin  , Oyowvi Mega Obukohwo  , Oyedokun Precious  , Akanbi Grace Bosede  , Dare Sarah Nene  and Adeniran Adebola Magret

Received: 11 January 2024;  Published: 03 April 2024;  doi: 10.21926/obm.geriatr.2402276

This review aims to bring attention to the growing issue of andropause, a condition that affects men as they age. The literature was identified by searching the major bibliographic databases, including PubMed, Google Scholar, EBSCOhost, Web of Science, and CINAHL. Studies were included if they focused on strategies for reducing and preventing andropause, published between 1980 and 2023. Andropause, which is often overlooked and misconceived, is the result of a decrease in testosterone production and can result in p [...]

by Jeffrey T. Apter  and Kaylee M. White

Received: 01 December 2019;  Published: 29 April 2020;  doi: 10.21926/obm.geriatr.2002116

The Amyloid and Tau Hypothesis of Alzheimer’s disease once thought to be the key have shown marginal results but are bolstered by the recent revival of the Aducanumab study and some positive data on some anti-Tau drugs. It still behoves us to look at other mechanisms which include whole blood transfusions, an Epigenetic approach, a-derivative of a Parkinson's drug a low dose of an anti-epileptic drug, an antibiotic against P Gingivitis and many new approaches not directly involving Amyloid and Tau. Other newer appr [...]

by Marika Haritos Paul  , Mary Beth Arensberg  , Judy R. Simon  , Satya S. Jonnalagadda  , Suzette L. Pereira  , Jamie S. Partridge  and Joseph A. Rosenthal

Received: 10 April 2020;  Published: 22 May 2020;  doi: 10.21926/obm.geriatr.2002120

Poor nutrition is linked to frailty and both poor nutrition and frailty are recognized risk factors for falls. This study examined the association between dietary protein intake and subsequent reported falls in community-dwelling older Americans with a history of falls. Other nutritional, functional, and sociodemographic-related variables were also considered in our model. This was a retrospective analysis using data from the U.S. Health and Retirement Study (HRS) and Health Care and Nutrition Study (HCNS), both fu [...]

by Ana Jessica Alfaro  , Soledad Argüelles-Borge  , Ashley M. Stripling  and Paula M. Brochu

Received: 17 September 2018;  Published: 29 March 2019;  doi: 10.21926/obm.geriatr.1901043

Background: The world’s aging population is growing and diversifying at an unprecedented rate. In preparation for this, the National Institutes of Health and the Centers for Disease Control and Prevention have issued calls to improve the overall health of older adults. A promising avenue of research to improve health in late life has been dedicated to subjective aging; the way people perceive their own aging process. The main objective of this empirical study was to investigate subjective aging in late life among e [...]

by Gary Stanton

Received: 18 August 2024;  Published: 22 October 2024;  doi: 10.21926/obm.icm.2404061

The Shenmen Point is an auricular acupuncture point that is also known in France as the Cosmonaut Point. It is widely utilized therapeutically for its property of reducing stress. In some ways it is a controversial point. Differences of opinion exist regarding the most appropriate name of the point, who discovered it first, its location within the triangular fossa, its best method of detection, its best method of stimulation, its actions, its indications, its contraindications, its therapeutic effects, and even its [...]

by Ioannis Syros  , Aggeliki Karantzali  and Xenia Anastassiou-Hadjicharalambous

Received: 11 April 2022;  Published: 15 November 2022;  doi: 10.21926/obm.neurobiol.2204146

PTSD is a serious mental health condition with a lifetime prevalence of 1% to 14% in the general population. Several studies have evaluated evidence-based treatment approaches for children and adolescents. Interventions focusing on trauma are considered first-line treatments. Trauma-Focused Cognitive Behavioral Therapy (TF-CBT) and a similar type of group intervention, the Cognitive Behavioral Intervention on Trauma in Schools (CBITS), have received the most empirical support from randomized controlled trials. More [...]

by Muhammad Qasim Zafar  , Ramisha Sajjad  , Muhammad Tuoqeer Anwar  , Muhammad Salman Mustafa  , Naveed Husnain  , Anas Bin Aqeel  and Muhammad Bilal Khan

Received: 01 October 2024;  Published: 10 February 2025;  doi: 10.21926/rpm.2501006

Metal Additive Manufacturing (MAM) process has been established as an industrial process for customized and intricate metallic components. It is one of the growing technologies proving its potential in numerous fields by introducing the latest processing methods. The significant growth in this technology is partially fueled by its ability to manufacture parts that could be performance-beneficial and commercially utilizable in various industries. The adaptability of metal AM processes has prompted innovation across [...]

by Jeet Chand  , Shiva Jha  and Sameer Shrestha

Received: 29 August 2022;  Published: 25 November 2022;  doi: 10.21926/rpm.2204026

Water recycling is a potential tool for reducing the dependency on traditional water sources, which would eventually reduce the likelihood of volumetric restrictions and their impacts on the water sector. Therefore, exploration, development, and use of alternative water sources are required for sustainable development. Scientific studies on the efficient and economical use of nontraditional water sources developed using the recycling process have attracted the attention of agriculturists, planners, and engineers fo [...]