by Malin Vestin Fredriksson  , Love Kull  , Anton Rönnblom  , Lennart Flygare  , Diana Berggren  and Krister Tano

Received: 26 March 2024;  Published: 25 July 2024;  doi: 10.21926/rpm.2403018

To develop a modular anthropomorphic phantom to evaluate the performance of radiological techniques for detecting pathologies in the temporal bone region. A phantom was constructed using a human skull, temporal bone specimen, and 3D-printed contour of a human skull. The human skull was embedded in tissue-equivalent plastic, with a cavity to hold the plastic jars containing the exchangeable freshly frozen human temporal bones. Subsequently, stepwise introduction and examination of different clinicopathological scena [...]

by Suhani Sharma  , Sonali Karhana  and Mohd. Ashif Khan

Received: 15 May 2025;  Published: 29 September 2025;  doi: 10.21926/rpn.2503021

Vitamin D, a fat-soluble secosteroid, plays a pivotal role beyond its functions in calcium and bone homeostasis. Emerging evidence suggests its involvement in glucose metabolism and insulin sensitivity, thus influencing the pathophysiology of Type 2 Diabetes Mellitus (T2DM). For the current review, a search was conducted across four major databases: PubMed, Embase, Google Scholar, and Web of Science. The aim was to identify relevant studies and clinical trials, published in English, reporting the mechanistic insigh [...]

by Recent Progress in Materials Editorial Office

Received: 26 February 2023;  Published: 27 February 2023;  doi: 10.21926/rpm.2301010

InterviewAn Interview with Assoc. Prof. Carlo SantulliRecent Progress in Materials Editorial OfficeLIDSEN Publishing Inc., 2000 Auburn Drive, One Chagrin Highlands, Suite 200, Beachwood, OH, USA; E-Mail: rpm@lidsen.com Recent Progress in Materials2023, volume 5, issue 1doi:10.21926/rpm.2301010Received: February 26, 2023Accepted: February 26, 2023Published: February 27, 2023

by Yoko Kawamura

Received: 15 May 2025;  Published: 30 October 2025;  doi: 10.21926/obm.geriatr.2504329

In Japan, a super-aging society, the development of Ikigai is considered the key to extending healthy longevity in national policy. Thus, activities provided by local governments are designed to encourage Ikigai. At this point, Ikigai has developed its conceptual understanding, which includes its distinctiveness from life purposes and other closely related concepts. Empirical studies using developed measurements have shown that Ikigai has an impact on the mental and physical health of older adults across countries [...]

by Fatemeh Mollaamin  and Majid Monajjemi

Received: 27 November 2023;  Published: 21 February 2024;  doi: 10.21926/obm.genet.2401214

As proof has recommended a close connection between COVID-19 and neurodegenerative disorders, this article aims to investigate the chloroquine (CLQ) drug as the SARS-CoV-2’s primary protease, which can prevent in vitro viral duplication of all diverse experiments to present. CLQ is an anti-viral drug enlarged by Pfizer, which can operate as an orally effective 3C-like protease inhibitor. In this study, CLQ has been assessed for its effectiveness against coronavirus by trapping it within a boron nitride nanoca [...]

by Giulio E. Lancioni  , Gloria Alberti  , Chiara Filippini  , Nirbhay N. Singh  , Mark F. O'Reilly  and Jeff Sigafoos

Received: 14 March 2024;  Published: 28 June 2024;  doi: 10.21926/obm.neurobiol.2402228

People with profound intellectual and multiple disabilities (PIMD) are generally isolated, with a high risk of reduced stimulation input and physical inactivity. One of the strategies available to mitigate this situation relies on using technology-aided programs delivering stimulation contingent on people’s basic responses/activation. The two studies reported here were intended to extend the evidence available in this area. Specifically, Study I assessed whether a technology-aided program, which enabled participant [...]

by Che Aishah Nazariah Ismail  , Nazlahshaniza Shafin  , Khairunnuur Fairuz Azman  , Idris Long  and Nor Syafinaz Yaakob

Received: 28 September 2024;  Published: 09 April 2025;  doi: 10.21926/obm.neurobiol.2502283

Chronic pain is a significant and global healthcare issue that hugely implies the quality of life and productivity of the affected individuals. It is challenging to treat and thus necessitates a deeper understanding of its underlying pathomechanisms to develop targeted interventions. Serotonin is one of the essential neurotransmitters involved in the propagation of pain signals through both ascending and descending pathways, acting via various receptor subtypes, including the 5-hydroxytryptamine receptor-6 (5-HT6R) [...]

by Brittany Montgomery  , Calvin Mammen  and Matt Golden

Received: 18 October 2024;  Published: 09 May 2025;  doi: 10.21926/obm.geriatr.2502311

Assistive technology (AT) interventions have shown promising results in supporting cognitive, social, and physical activities in persons living with dementia (PLWD) and their caregivers. Despite strong evidence of the effectiveness of AT, PLWD and their caregivers can disengage with the technology after it is used for a time – i.e., the “stickiness challenge”. Diminished use of AT reduces the opportunity for it to have optimal impact. We asked whether the opportunity to engage in cognitive games may enhance continu [...]

by OBM Geriatrics Editorial Office

Received: 09 October 2022;  Published: 09 October 2022;  doi: 10.21926/obm.geriatr.2204207

Open AccessOBM GeriatricsInterviewAn Interview with Dr. David G. SmithardOBM Geriatrics Editorial OfficeLIDSEN Publishing Inc., 2000 Auburn Drive, One Chagrin Highlands, Suite 200, Beachwood, OH, USA; E-Mail: geriatrics@lidsen.comOBM Geriatrics 2022, volume 6, issue 4 doi:10.21926/obm.geriatr.2204207Received: October 09, 2022Accepted: October 09, 2022Published: October 09, 2022

by Hicham Bouchahta  , Zhour EL Amrani  , Siham Chafai Elalaoui  , Fatima Ouboukss  , Aziza Sbiti  , Laila Sbabou  , Thomas Liehr  , Abdelaziz Sefiani  and Abdelhafid Natiq

Received: 14 October 2024;  Published: 27 January 2025;  doi: 10.21926/obm.genet.2501282

Cat-eye syndrome (CES) is a rare genetic disease first reported in 1965. The estimated prevalence of CES is 1:50,000 to 1:150,000, and it is typically associated with an inverted duplicated small supernumerary marker chromosome (sSMC) derived from chromosome 22. The specific chromosomal band involved in CES causing partial tetrasomy is 22q11.21, where chromosomal rearrangements occur due to the presence of low-copy repeats (LCR22). The phenotype of CES is extremely diverse, ranging from normal to multiple abnormali [...]