by Bruno A Lima

Received: 15 December 2023;  Published: 11 March 2024;  doi: 10.21926/obm.transplant.2401208

Human Leucocyte Antigens (HLA) constitute a highly polymorphic set of genes pivotal to the immune response. The HLA heterozygous advantage hypothesis assumes that heterozygous individuals at the HLA level have a wider range of peptides for T cell recognition than homozygous individuals. Consequently, they possess an enhanced capacity to trigger a targeted immune reaction. The divergent allele advantage hypothesis is an extension of heterozygous advantage, considering the excessive sequence divergence between allele [...]

by Mimi Mun Yee Tse  , Shamay Sheung Mei Ng  , Vivian Lou  , Raymond SK Lo  , Daphne Sze Ki Cheung  , Paul H Lee  , Shuk Kwan Tang  , Siu Hang Leung  and Percy Poo-See Tse

Received: 02 August 2023;  Published: 15 September 2023;  doi: 10.21926/obm.neurobiol.2303183

The COVID-19 pandemic started at the beginning of 2020. It significantly impacted the older adults in Hong Kong, with most of the community centers and elderly centers being closed down under various restrictive measures. Thus, community-based health promotion activities were temporarily paused, which decreased older adults’ health-promoting behaviors and motivation to stay active. This research aimed to improve the quality of life and the health of older adults with chronic pain through the pain management program [...]

by Rim Werheni Ammeri  , Wafa Hassen  , Ines Mehri  , Nesrine Khelifi  and Abdennaceur Hassen

Received: 29 July 2022;  Published: 18 November 2022;  doi: 10.21926/rpm.2204024

Bioaugmentation by Pseudomonas strains is widely used for the removal of pollutants in wastewater. In this study, we aimed to determine the removal of pentachlorophenol (PCP, 800 mg·L–1) in secondary wastewater by the bioaugmentation process. We determined the effects of using three surfactants, namely sodium dodecyl sulfate (SDS), cetyl-tri-methyl-ammonium bromide (CTAB), and Tween 80 for PCP removal. We determined the effect of the role of PCP surfactant for the biofilm and auxin production of the se [...]

by Andrey Nasledov  , Liubov Tkacheva  and Sergey Miroshnikov

Received: 03 July 2024;  Published: 27 November 2024;  doi: 10.21926/obm.neurobiol.2404259

The work identifies the factor structure of autism symptoms in older preschoolers to check their age dynamics. An Autism Marker Questionnaire containing 330 potential symptoms of autism spectrum disorder (ASD) was developed to be implemented as an online survey. 501 children were examined (371 with ASD) already classified by experts as a group of ASD, typically developing (TD) or with developmental delay (DD). At the exploratory stage, a relatively simple 8-factor structure was obtained: Speech Understanding (SU), [...]

by Michal Kawka  , Tamara MH Gall  and Long R Jiao

Received: 25 February 2019;  Published: 05 June 2019;  doi: 10.21926/obm.hg.1902022

Background: Severe necrotising pancreatitis (SNP) is characterised by high mortality, severe complications and bad prognosis despite progress in understanding of aetiology and progression of the disease. Traditionally, necrotic changes were removed by open necrosectomy but the paradigm has shifted towards more conservative management and minimally-invasive surgical procedures. However, there is still no consensus on the best management pathway. Minimally-invasive procedures percutaneous drainage, endoscopic transl [...]

by Athina Markouizou  , Evrydiki Michali  , Christina Mamareli  , Jane Anastassopoulou  , Panayiota Kolovou  , Ioannis Mamarelis  and Theophile Theophanides

Received: 12 September 2022;  Published: 24 November 2022;  doi: 10.21926/obm.geriatr.2204215

Breast cancer affects the female population worldwide. Radiotherapy (RT) is part of the therapeutic modality in the management of breast cancer, after radical mastectomy or conserving surgery. The FTIR spectroscopic "marker bands" will lead us to approach the mechanism of skin damage due to the interaction of ionizing radiation and skin, on a molecular level at the very early stages. FT-IR spectroscopy, breast digital pictures, and ImageJ software were used in the study. Healthy breast skin was irradiated ex-vivo w [...]

by Alexander G. Mikhailov  and Ivan I. Vashlaev

Received: 08 June 2022;  Published: 27 September 2022;  doi: 10.21926/aeer.2203037

Mineral resources in the subsoil are classified as exhaustible. One of the ways to potentially replenish the sources of mineral resources is presented in the materials of these studies. In this article, we studied the natural formation in the bowels of the array of zones of high concentrations of compounds of useful components. We aimed to develop the technological methods of mass transfer and directed deposition of useful components. The technological transition of mineral resource extraction from the “gathering” [...]

by Paayal Naidu  , William Sandawana Majoni  , Toby Coates  and Manohar Mogulla

Received: 11 May 2023;  Published: 04 September 2023;  doi: 10.21926/obm.transplant.2303194

Thrombotic microangiopathy (TMA) in kidney transplant recipients is uncommon and difficult to manage, often with poor graft outcomes [1]. This is a complex and interesting case of an older, highly sensitised kidney transplant recipient who presented with de novo post-transplant TMA in the setting of antibody mediated rejection (ABMR), with other drivers being tacrolimus toxicity, cytomegalovirus (CMV) infection and anti-SARS-CoV-2 BNT162b2 mRNA vaccination. This led to rapid, irrecoverable graft loss. 76-year-old f [...]

by Elsa Abreu  , Catarina Simões  and Rita Figueiredo

Received: 02 March 2024;  Published: 31 July 2024;  doi: 10.21926/obm.geriatr.2403283

Skin is the largest organ of the human body. Skin changes can result from natural ageing, as well as from acute or chronic diseases and failure of body systems. Various types of wounds are identified in Palliative Care, and terminal pressure ulcers are often incorrectly classified. This case study highlights the importance of recognizing skin ulcers in patients’ last hours and days of life as a diagnostic indicator for impending death. The first focus of nursing care was pain management and maintaining skin integri [...]

by Oleksandr Beshta  , Gennadiy Pivnyak  , Oleksandr Beshta Jr  , Roman Borovik  , Cáceres Cabana Edgar  and Adam Smolinski

Received: 17 August 2022;  Published: 14 November 2022;  doi: 10.21926/rpm.2204023

In a lithium-ion battery, the crossing of its charging–discharging curves represents an unambiguous current capacity. The reproduction of a complete charging–discharging cycle defines the maximum possible charge for a current battery state. When obtaining of the curves experimentally, one should consider the duration of polarization or depolarization. It is reported that the battery capacity depends considerably on the value of the battery’s internal resistance as this value defines the location of the actual charg [...]