by Aline Duarte Folle  , Kimberly C Paul  , Cynthia D Kusters  , Jeff M Bronstein  , Adrienne M Keener  and Beate Ritz

Received: 30 June 2020;  Published: 26 August 2020;  doi: 10.21926/obm.geriatr.2003131

Insomnia and excessive daytime sleepiness are the most common sleep disturbances in Parkinson’s disease. This study aims at better understanding how severity of PD motor and non-motor features and dopaminergic treatments contribute to these sleep symptoms in the first decade of PD. Data from a community-based cohort of PD patients was used to model cross-sectional PD-related risk factors for insomnia and EDS sleep scores using linear regression models adjusted for age, gender, and PD duration. Longitudinal changes [...]

by Shih-Ang Hsu

Received: 25 July 2021;  Published: 02 September 2021;  doi: 10.21926/aeer.2103022

Spatial relation between wind stress and storm surge during two hurricanes in 2020 is investigated. It is found that, during Laura’s landfall, the area inside of 65 knots (34 m s -1) isotach or line of equal wind speed can produce up to 18 ft (5.5 m) inundation and during Delta, the area inside of 50 knots (26 m s -1) up to 11 ft (3.3 m) high water level above the ground. The tropical cyclone (TC) surface analysis near landfall by the Regional and Mesoscale Meteorology Branch (RAMMB) is recommended as a first [...]

by Marina Moguilevitch  and Tracey Straker

Received: 05 July 2020;  Published: 12 November 2020;  doi: 10.21926/obm.transplant.2004123

Clinical presentation and progression of Wilson’s disease can be diverse in different groups of patients. While young children most likely to present with acute or chronic liver failure, older children and adults may exhibit extrahepatic manifestation like neuropsychiatric, cardiac, renal, pancreatic and several others. Diagnosis of Wilson’s disease is based on the combination of specific clinical findings, laboratory and genetic testing. There are different modalities of treatment available for this condition. Liv [...]

by Aarthi Madhavan  , Isaac Sia  , Giselle Carnaby  and Michael Crary

Received: 29 October 2020;  Published: 22 February 2021;  doi: 10.21926/obm.geriatr.2101158

Individuals with acute stroke on nonoral feeding regimens frequently develop pneumonia, questioning the long-held belief that pneumonia in stroke patients is a caused by food and liquid aspiration alone. Refluxate and colonized oral secretions are thought to contribute to an acidic oropharyngeal environment. If aspirated, these colonized oral secretions with increased acidity, can result in increased risk to the respiratory system. This study aimed to investigate the relationship between pharyngeal acidity, dysphag [...]

by Boel De Paepe

Received: 28 February 2019;  Published: 16 May 2019;  doi: 10.21926/obm.genet.1902079

In order to successfully recover from damage, skeletal muscle tissue requires proper activation of a tightly orchestrated repair program. Non-coding RNAs actively participate in this complex process of demolition and rebuilding. In this review, the contribution of dysregulated non-coding RNA expression to disease-associated pathological changes is explored in hereditary muscular dystrophies and idiopathic inflammatory myopathies. Disturbances in spatiotemporal expression of non-coding RNAs appear to be key factors [...]

by M Wehming  , A Briem-Richter  , R Ganschow  , F Brinkert  , B Winkler  , L Fischer  and Enke Grabhorn

Received: 07 June 2020;  Published: 25 January 2021;  doi: 10.21926/obm.transplant.2101135

Some malignancies such as hepatoblastoma may be an indication for liver transplantation (LT) or some, for example, post-transplant lymphoproliferative disease (PTLD) may develop after successful LT. An immunosuppressive therapy after LT can promote the recurrence of the primary malignancy. The mammalian target-of-rapamycin inhibitors (mTORi) are immunosuppressive agents with anti-tumor properties. We examined the impact of everolimus (EVL) together with calcineurin inhibitors on allograft outcome and patient surviv [...]

by Sonal Mishra  , Neha Kumari  , Varsha K. Singh  and Rajeshwar P Sinha

Received: 18 January 2023;  Published: 03 August 2023;  doi: 10.21926/aeer.2303041

Cyanobacteria have great potential as a platform for biofuel production because of their fast growth, ability to fix CO2 gas, and genetic tractability. They also preserve the sustainability of an ecosystem without harming the environment. High-performance biofuels made from cyanobacteria can be utilized as a base for the production of green energy. Although a lot of studies have been conducted where plants and crops are used as the source of energy, cyanobacteria have been reported to have a more efficient photosyn [...]

by Jéssica A.P. Ponciano  and Marcelo S. Batista

Received: 01 December 2021;  Published: 26 January 2022;  doi: 10.21926/cr.2201002

In this paper, the relationship between activity and structure of Cu2+ in different chemical environments of Cu-BETA, La2CuO4, and CuO nanocatalysts was systematically investigated for acetonitrile combustion. The study revealed that exchanged and octahedral species of Cu2+ coexist in Cu-BETA, while octahedral species are dominant in CuO and La2CuO4. All nanocatalysts achieved high conversion rates of acetonitrile, which rapidly increased with temperature. CuO and La2CuO4 led to the formation of undesired products [...]

by Koorosh Goudarzi  and AliReza R. Taghizadeh

Received: 31 December 2022;  Published: 06 February 2023;  doi: 10.21926/jept.2301006

In this paper, due to the importance of energy recovery from internal combustion engines and the increasing human growing need for power and refrigeration, a two-cycle power and refrigeration system consisting of an organic Rankine cycle and an ejector refrigeration cycle is investigated analytically. The proposed system with the ability to use the ejector as an effective and economical system, can produce simultaneous power and refrigeration by drawing thermal energy from the exhaust gas and engine coolant in the [...]

by Deborah H. John  , Patrick Abi Nader  and Katherine Gunter

Received: 29 October 2018;  Published: 06 January 2020;  doi: 10.21926/obm.geriatr.2001098

Physical inactivity is the fourth leading risk factor for global mortality and as such, it is critical that physical activity guidelines for health consider equitable access to physical activity opportunities for all, including those aged 65 years and older. The purpose of this study was to examine the intersections of attributes of older people (e.g. income, gender, age, health, physical activity) and attributes of the places they live (e.g. rurality, public transit, sidewalks, parks, community centre) to explain [...]