by Ryan Anthony  , Michael J. Macartney  and Gregory E. Peoples

Received: 12 November 2024;  Published: 19 March 2025;  doi: 10.21926/rpn.2501004

Long-chain omega-3 fatty acids (LCn-3PUFA), including eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), support heart function during exercise and recovery by incorporating into the cardiac cell membranes. Traditionally sourced from fish and fish oil, algae-derived LCn-3PUFA have become alternative in supplemental forms. This study evaluated whether 12 weeks supplementation of a microencapsulated algal oil, delivered as chewable tablets, would perform equivalently to fish-derived LCn-3PUFA in boosting the [...]

by Farida Arisanti  , Tertianto Prabowo  , Putri Endyana  and Apichana Kovindha

Received: 03 October 2024;  Published: 18 March 2025;  doi: 10.21926/obm.neurobiol.2501279

Spinal tuberculosis (TB), an extrapulmonary manifestation of TB, primarily involves one or multiple vertebrae, with a high prevalence at the thoracolumbar region, which can compromise spinal cord integrity and result in severe sequelae such as paraplegia, bladder and bowel dysfunction, and mobility limitation. This study aimed to review medical, surgical, and rehabilitation management, clinical outcomes, and prognostic factors of spinal TB with spinal cord injury (SCI). Research was conducted utilizing databases su [...]

by Victoria M. Dahl  , Alyssa L. Chimiklis  , Sarah Peralta  , Yasmin Siddiqui  and Anil Chacko

Received: 15 August 2024;  Published: 18 March 2025;  doi: 10.21926/obm.icm.2501015

Schools have made commendable efforts to incorporate yoga and mindfulness programs to address the wellbeing of students; however, research on the efficacy of school-based yoga and mindfulness programs is still in its infancy, particularly with school-aged students at risk of developing externalizing disorders. Much of the research has also focused on evaluating interventions implemented by researchers, rather than evaluating those implemented by the school and its staff. The aim of this pilot study was to evaluate [...]

by Amy J Hopper  and Angus M Brown

Received: 19 May 2024;  Published: 17 March 2025;  doi: 10.21926/obm.neurobiol.2501278

The legacy of Hodgkin and Huxley rests on their squid giant axon studies, which were summarised in an empirical model of impressive predictive power that successfully quantified the permeability changes of excitable membranes and accurately reconstructed the action potential. Hodgkin and Huxley applied the independence principle to their experimental data in order to reveal potential mechanism(s) of trans-membrane ion movements. This was motivated by their lack of information on the manner in which ions crossed the [...]

by Mojtaba Ehsanifar  and Zeinab Yavari

Received: 13 December 2024;  Published: 16 March 2025;  doi: 10.21926/obm.neurobiol.2501277

The pervasive presence and enduring existence of micro and nanoplastics in the environment render their exposure to humans and aquatic creatures unavoidable. Research indicates these tiny plastic particles can be taken in by aquatic beings and mammals. Once within the body, micro and nanoplastics have the capability to infiltrate the brain, although the level of penetration and the subsequent neurotoxic effects are not fully explored. Previous studies indicate that metal (oxide) nanoparticles can enter the brain an [...]

by Babak Sokouti

Received: 30 October 2024;  Published: 14 March 2025;  doi: 10.21926/obm.neurobiol.2501276

Delirium is an acute neurocognitive disorder marked by disruptions in attention, cognition, and awareness, particularly prevalent among older and critically ill patients. This study applies a systems biology framework to dissect the molecular underpinnings of delirium and evaluate natural compounds for potential therapeutic roles. Through bioinformatics analyses, key biomarkers related to delirium, including IL6, AKT1, JUN, APP, and PPARGC1A, were identified, implicating pathways tied to neuroinflammation, oxidativ [...]

by Jennifer Vasquez  , Michele Quill  and Chase Bossart

Received: 17 January 2025;  Published: 14 March 2025;  doi: 10.21926/obm.icm.2501014

In this qualitative study, the impact of therapeutic Viniyoga on health and healing was explored from the perspective of 14 Viniyoga therapists who were interviewed on their perceptions of how yoga therapy contributes to the health and healing of their clients. A philosophical definition of Therapeutic Viniyoga was developed. Three themes related to health and healing from the perspective of Viniyoga therapists were identified using NVivo and Interpretative Phenomenological Analysis procedures: The definition of he [...]

by Liana Spytska

Received: 04 December 2024;  Published: 14 March 2025;  doi: 10.21926/obm.neurobiol.2501275

The relevance of studying the cognitive and behavioral dynamics of psychopathy lies in its importance for improving diagnosis, therapeutic interventions, and reducing crime, thereby contributing to public safety. This study aimed to investigate how cognitive and behavioral mechanisms influence psychopathy. A combination of methods was employed, including the Levenson Self-Report Psychopathy Scale, semi-structured interviews, and the analysis of non-verbal reactions. The sample consisted of eight participants (four [...]

by Koji Kawago  , John A Farag  , Yujiro Kawai  , Umayr Syed  , Eric Pfrender  , Satoshi Miyairi  and Yasuhiro Shudo

Received: 21 October 2024;  Published: 14 March 2025;  doi: 10.21926/obm.transplant.2501242

Heterotopic heart transplantation (HHT) in rats is a valuable tool for cardiac transplantation research. While abdominal HHT has been established in rats for nearly 90 years, novel approaches involving cervical and femoral techniques have also been explored. The abdominal HHT model, despite its long history, is technically demanding and has a steep learning curve. In contrast, the cervical HHT model enables surgeons with more basic microsurgical skills to achieve competency more quickly while producing comparable o [...]

by Ajay Kumar  and Juveriya Israr

Received: 03 August 2024;  Published: 12 March 2025;  doi: 10.21926/obm.transplant.2501241

Allogeneic stem cell transplantation (allo-SCT) improves the treatment of hematopoietic cancer and non-malignant disease. In this case, stem cells from a genetically similar but not identical donor may stimulate immune-mediated tumor cell destruction. Allogeneic stem cell transplantation, or allo-SCT, has significantly extended the life expectancy of numerous people. Nevertheless, complications such as infections, graft-versus-host disease (GVHD), and recurrence continue. This paper provides a thorough analysis of [...]