by Mohammad-Reza Ghasemi  , Maryam Mirahmadi  , Hadi Bayat  , Morteza Sheikhi Nooshabadi  , Sanaz Jamshidi  , Shadab Salehpour  , Reza Mirfakhraie  , Fatemeh Fazeli  , Mohammad Miryounesi  and Milad Gholami

Received: 22 November 2024;  Published: 14 April 2025;  doi: 10.21926/obm.genet.2502291

Knobloch Syndrome (KS) is a rare genetic disorder characterized by ocular abnormalities and central nervous system (CNS) defects, which are attributed to collagenopathy. The primary gene implicated in KS is COL18A1, which encodes the alpha chain of type XVIII collagen. This type of collagen functions as a proteoglycan, predominantly located in the basement membrane of human tissues. This study examined an Iranian female presenting with symptoms of horizontal nystagmus, strabismus, and suspected vision loss, with a [...]

by Recent Progress in Science and Engineering Editorial Office

Received: 07 April 2025;  Published: 11 April 2025;  doi: 10.21926/rpse.2502008

by Modupe Akintomide  , Xinyue Zhang  , Lota Iwuagwu  and Mary Ramos

Received: 03 October 2024;  Published: 10 April 2025;  doi: 10.21926/obm.geriatr.2502306

About 90% of people living with Alzheimer's disease and related dementias experience behavioral and psychological symptoms during the course of the disorder. Although extensive research exists on the roles of informal caregivers in dementia care, their abilities to manage behavioral symptoms and the resources they turn to for support remain understudied. This phenomenological study explored informal caregivers' experience, knowledge sources, and self-initiated strategies for managing behavioral symptoms of dementia [...]

by Fabiana Cristina Lima Barbosa  , Ana Carolina Teles de Aquino  , Marcos Paulo Gomes Mol  and Raphael Tobias de Vasconcelos Barros

Received: 16 October 2024;  Published: 10 April 2025;  doi: 10.21926/aeer.2502018

When addressing Healthcare Waste Management (HCWM), numerous factors play a crucial role in ensuring its safety and environmentally responsible handling within institutional processes. Recognizing this imperative, this study employed the Analytical Hierarchical Process (AHP) methodology to establish a comprehensive assessment of 10 primary criteria and 66 sub-criteria concerning the governance and operational aspects of Healthcare Waste Management. This evaluation was based on the insights of 14 specialists in the [...]

by Che Aishah Nazariah Ismail  , Nazlahshaniza Shafin  , Khairunnuur Fairuz Azman  , Idris Long  and Nor Syafinaz Yaakob

Received: 28 September 2024;  Published: 09 April 2025;  doi: 10.21926/obm.neurobiol.2502283

Chronic pain is a significant and global healthcare issue that hugely implies the quality of life and productivity of the affected individuals. It is challenging to treat and thus necessitates a deeper understanding of its underlying pathomechanisms to develop targeted interventions. Serotonin is one of the essential neurotransmitters involved in the propagation of pain signals through both ascending and descending pathways, acting via various receptor subtypes, including the 5-hydroxytryptamine receptor-6 (5-HT6R) [...]

by Sara Evans  , Ariba Moin  and Ashwini Arjuna

Received: 13 June 2024;  Published: 09 April 2025;  doi: 10.21926/obm.transplant.2502246

Varicella-zoster virus (VZV) significantly impacts the central and peripheral nervous systems, particularly in immunocompromised individuals. This case report details a rare presentation of VZV meningoencephalitis in a 42-year-old woman with interstitial lung disease and connective tissue disease undergoing lung transplant evaluation who presented with a thunderclap headache and a new-onset seizure. Despite normal initial MRI findings, further investigation with PCR of the cerebrospinal fluid (CSF) revealed the pre [...]

by Alessia Bartolacci  , Fabrizio Stocchi  , Vilberto Stocchi  and Sabrina Donati Zeppa

Received: 17 November 2024;  Published: 08 April 2025;  doi: 10.21926/rpn.2502007

In recent years, there has been an alarming increase in the incidence of inflammatory bowel disease (IBD), which includes both Crohn's disease (CD) and ulcerative colitis (UC), particularly in Western countries. This chronic condition is intricately linked to the composition and health of the gut microbiota (GM) — a complex community of microorganisms residing in the gastrointestinal (GI) tract. Despite extensive research, the underlying pathogenesis of IBD remains poorly understood, making it a wide area of invest [...]

by Ousman Bajinka  , Mamtuti Panneh  , Sang Mendy  , Amadou Barrow  , Haddy Bah  , Lamarana Jallow  , Jarry Jallow  , Kaddy Drammeh  , Kaddijatou Kah  , Oulimatou Lateef  , Mariama A Bah  , Isatou K Sillah  , Fatoumata Bah  , Nyima Ceesay  , Mariama Jaiteh  and Yurong Tan

Received: 31 August 2024;  Published: 08 April 2025;  doi: 10.21926/rpn.2502006

The adverse effects of maternal passive smoking during pregnancy on offspring health remain understudied in sub-Saharan Africa, particularly in The Gambia, where smoke-free regulations are limited. To determine the prevalence of maternal passive smoking (MPS) during pregnancy and investigate its associations with adverse pregnancy outcomes and offspring health complications in The Gambia. A cross-sectional study was conducted in February 2023 among 401 mothers with children under 5 years in urban and rural regions [...]

by Fatima A. M. Lino  , Kamal A. R. Ismail  , Waldir A. Bizzo  , Lucas A. N. da Silva  and João P. S. Veiga

Received: 23 September 2024;  Published: 07 April 2025;  doi: 10.21926/aeer.2502017

Urbanization driven by industrialization and population growth amplifies food consumption and reinforces the need for more fuels and energy. However, the expansion of biofuels can impose risks on long-term food security. This paper examines potential alternative crops for energy generation and food production, including those used by family farmers and their associations, to decentralize energy production and utilization as a crucial pillar of the global energy transition. Cassava, corn, and sugar beet are the chos [...]

by Lindsay E. Turgeon-Brown

Received: 19 November 2024;  Published: 07 April 2025;  doi: 10.21926/obm.icm.2502017

Teachers face at-work risk factors including compassion fatigue, burnout, dealing with violence, and a teacher shortage. A review of the literature shows that self-care can have positive benefits that mitigate and help to buffer these at-work risk factors This study examines teachers’ stories of self-care. The data suggests that self-care is a positive practice for teachers professionally and personally.