by Debora Di Jorio

Received: 14 April 2020;  Published: 22 June 2020;  doi: 10.21926/obm.neurobiol.2002063

The story of each individual is essentially the story of their learning processes and relationships from the moment they were born. Indeed, the story of learning processes is merely a constant stratification of experiences based on biological and neurofunctional features that are influenced by genetic and cultural factors and subject to environmental stimuli constantly reshaping their behaviour.Neuroscientific studies conducted over the past decades have highlighted a unique feature of the human nervous system, cal [...]

by Zheer Al-Mashhadi  , Rikke Viggers  , Rasmus Fuglsang-Nielsen  , Bente Langdahl  , Peter Vestergaard  , Søren Gregersen  and Jakob Starup-Linde

Received: 02 April 2020;  Published: 18 June 2020;  doi: 10.21926/obm.geriatr.2002123

Type 2 diabetes mellitus (T2DM) and osteoporosis are two major public health concerns worldwide, contributing to morbidity and mortality in the elderly. Aging is one of the most significant risk factors for low bone mass, bone fragility, and fractures. Among the several comorbidities that affect the elderly with diabetes, increased fracture risk is a relatively recently discovered complication. Generally, individuals with T2DM exhibit higher bone mineral density, which complicates the assessment of fracture risk. D [...]

by Clarissa E.H. Fang  , Li Guo  , Daniel Hill  , Timothy E. Yap  and M. Francesca Cordeiro

Received: 16 April 2020;  Published: 15 June 2020;  doi: 10.21926/obm.neurobiol.2002062

Neuroprotection in glaucoma is any medical treatment by which decline in visual function can be slowed or prevented by supporting the health and survival of neural cells, independent of lowering of intraocular pressure (IOP). This is achieved by targeting mechanisms to inhibit or delay retinal ganglion cell death and promote cell survival pathways. Despite demonstrating promising results in preclinical trials, many neuroprotective strategies have failed to show success in subsequent clinical trials. Of the clinical [...]

by Yi-Chia Liao  , Chun-Hway Hsueh  and Wen-Shin Lee

Received: 16 May 2020;  Published: 15 June 2020;  doi: 10.21926/rpm.2002014

Inspired by the application of metallic glass sheet as face material for improving the performance of golf clubs, the present work was aimed to explore the application of thin-film metallic glass (TFMG) coatings for enhancing the performance of strings. In order to achieve this aim, badminton strings were coated with TFMG coatings of different thicknesses. The compositions of these TFMG coatings were analyzed using an electron probe micro-analyzer. The amorphous structure of the film was verified using X-ray diffra [...]

by Brian C. Keller  , Sadia Z. Shah  and Amy Pope-Harman

Received: 24 April 2020;  Published: 15 June 2020;  doi: 10.21926/obm.transplant.2002113

Systemic capillary leak syndrome is a disorder characterized by recurrent, life-threatening episodes of acute capillary hyperpermeability resulting in edema and hypovolemic shock. We report a case of systemic capillary leak syndrome in a lung transplant recipient who developed recurrent episodes of volume overload, respiratory failure, and acute kidney injury in association with hypotension and hypoalbuminemia. Initiation of monthly high dose intravenous immunoglobulin prophylaxis effectively abrogated the syndrome [...]

by Ioannis Syros  , Panagiota Pervanidou  , Charis Liapi  , Filia Apostolakou  , George P Chrousos  and Gerasimos Kolaitis

Received: 01 March 2020;  Published: 11 June 2020;  doi: 10.21926/obm.neurobiol.2002060

Data available on possible associations of lipids, steroid levels, and depression are conflicting. This study investigated their possible associations in a sample of youth with depression. Ninety-eight youth with depression and individually matched healthy volunteers on the basis of age and sex were enrolled for the study. The two groups had nearly similar body mass index. After fasting overnight, they underwent blood sampling for triglycerides (TG), total cholesterol, low-density lipoprotein, high-density lipoprot [...]

by Tania Re  and Giuseppe Vitiello

Received: 30 April 2020;  Published: 11 June 2020;  doi: 10.21926/obm.neurobiol.2002061

The present report discusses brain visual experiences in conditions of low degree of openness of the brain toward the environment, for example, while dreaming, during meditation, or in non-ordinary brain activity states such as under the effects of psychoactive substances, in the state of coma, or in other states of reduced sensory perception, among others. In the present report, for brevity, such states are referred to as brain-mind visual experiences, implying that such a visual activity is not one connected to t [...]

by Ryan J. Clarke  and David A. Miller

Received: 15 April 2020;  Published: 09 June 2020;  doi: 10.21926/jept.2002010

As wind turbine blades grow longer, new design parameters gain additional importance such as blade weight, tip deflection and material cost. These parameters require designers to relook at carbon fiber as a potential design solution. However, the composite materials in wind turbine blades are subjected to significant compressive loading, and the compressive strength of carbon fiber reinforced polymer (CFRP) composites is much lower than its tensile strength. This reduction in compression strength is due to a change [...]

by Robert B. Diller  , Robert G. Audet  , Mediha Gurel  , Eric E. Lee  , Aaron J. Tabor  , Peter McFetridge  and Robert S. Kellar

Received: 25 September 2019;  Published: 09 June 2020;  doi: 10.21926/obm.transplant.2002112

Mesenchymal Stromal/Stem Cells (MSCs) were originally discovered in the 1970s. MSCs are considered a multipotent population that retain tri-lineage differentiation. These cells can be sourced from a variety of tissues, including bone marrow, adipose, molar pulp, and birth tissues. Historically varying definitions of MSCs have existed, but in 2006, the International Society for Cellular Therapy (ISCT) set forth a standardized, minimal criteria for MSCs, including plastic adherence, differentiation into osteoblasts, [...]

by Jacques De Reuck  , Florent Auger  , Nicolas Durieux  , Claude-Alain Maurage  , Vincent Deramecourt  , Charlotte Cordonnier  , Florence Pasquier  , Didier Leys  and Regis Bordet

Received: 06 April 2020;  Published: 04 June 2020;  doi: 10.21926/obm.geriatr.2002122

Regional brain atrophy and an escalation in vascular risk are associated to increasing age in normal cognitive healthy persons. The present post-mortem study compares the incidence of cerebrovascular lesions between young-aged, middle-aged, and elderly cognitive normal persons with additional 7.0-tesla MRI). The patients consisted of 10 young adults, 20 middle-aged adults, and 14 elderly ones. In addition to the macroscopic visible cerebrovascular lesions, a whole coronal section of a cerebral hemisphere was taken [...]