Table of Content

Open Access Original Research

BESS Sizing Optimization Combined with Optimal Scheduling Method Considering the Battery Degradation Using PSO

Received: 17 June 2025;  Published: 24 October 2025;  doi: 10.21926/jept.2504015

Abstract

Recently, renewable energy projects using storage systems have gained significant attention. This innovative technology requires a comprehensive investigation to overcome the technical and economic issues, which are related to optimal storage system capacity and operational requirements. In this study, an extensive battery energy storage system (BESS) sizing method was proposed considering four variables: charging and discharging scheduling, state of charge, BESS rate energy and power capacity, and degradation effe [...]

1232 4343

Open Access Original Research

Immunologic Response after COVID-19 Vaccination in Heart Transplant Recipients

Received: 30 June 2025;  Published: 21 October 2025;  doi: 10.21926/obm.transplant.2504259

Abstract

To date, all large-scale randomized controlled trials for COVID-19 vaccines have excluded solid organ transplant recipients; therefore, the effectiveness and safety of COVID-19 vaccines in preventing coronavirus infection using COVID-19 vaccines in patients with heart transplants have not been sufficiently studied. This paper presents the characteristics of humoral and cellular immunity in heart transplant recipients following vaccination against coronavirus infection. The study group consisted of 40 patients who u [...]

570 2431

Open Access Review

Mycotoxins Exposure: Neuroinflammation, Cognitive Decline and Behavioral Alteration

Received: 13 June 2025;  Published: 21 October 2025;  doi: 10.21926/obm.neurobiol.2504305

Abstract

Evidence from recent studies has suggested a significant association between mycotoxin exposure and neuroinflammation, potentially contributing to the onset of neurocognitive disorders during key developmental stages of the brain. Various research highlights how exposure to these toxins is correlated with a decline in cognitive performance, reduced motor skills, and behavioral issues. Mycotoxins are also implicated in interfering with neuronal signaling pathways and the functioning of neurotransmitters, which may l [...]

1043 5878

Open Access Review

Impact of Heavy Metals as Trace Elements on the Ecosystem and Health

Received: 10 June 2025;  Published: 21 October 2025;  doi: 10.21926/rpn.2504023

Abstract

Heavy metals are integral parts of our environment, originating initially from the universe and used in the industry, which may contribute to pollution. This book chapter aims to address the impact of heavy metals on the ecosystem and human health. Among the 32 heavy metals, eight belong to the group of essential ones: cobalt, copper, iron, manganese, molybdenum, nickel, selenium, and zinc. They were necessary in physiological amounts for the evolution of flora and fauna, including humans on earth, and are still ne [...]

1448 10420

Open Access Editorial

Life Sciences Worldwide – Global Perspectives and Networking for International Professionals1

Received: 15 October 2025;  Published: 16 October 2025;  doi: 10.21926/obm.icm.2504044

Abstract

The International Exchange of Professionals – Thematic Event in Life Science, held on October 15-17, 2025, in Nice, France, inaugurated a global congress series focused on frontier topics in biomedical sciences. This editorial summarizes the first day of the event, including the opening ceremony, keynote forum, and welcome banquet. With more than 150 participants from over 35 countries, the event created a platform for cross-disciplinary exchange and collaboration. Key themes included translational medicine, neurom [...]

673 2555

Open Access Research Article

Potential Synergistic Interaction Between Curcumin and Sorafenib Enhances Cytotoxicity in NCI-H5222 Lung Cancer Cells

Received: 25 August 2025;  Published: 15 October 2025;  doi: 10.21926/obm.genet.2504313

Abstract

Non-small cell lung cancer (NSCLC), accounting for approximately 85% of lung cancer cases, remains a leading cause of cancer-related mortality. Genetic alteration such as EGFR mutations, tobacco exposure, and resistance to apoptosis, slows its progression and limits therapeutic success. Although targeted therapies and immunotherapy have improved outcomes for select patients, resistance remains a major challenge, highlighting the need for more effective treatments. This study investigated the potential synergistic i [...]

718 3186

Open Access Review

Bridging Togo’s Energy Gap: Renewable Energy Potentials, Policy Challenges, and Strategic Pathways for Sustainable Development

Received: 22 December 2024;  Published: 13 October 2025;  doi: 10.21926/jept.2504014

Abstract

This work investigates the potential of renewable energy to significantly reduce Togo’s energy deficit, offering a critical analysis of the country’s current energy landscape. It evaluates the availability and viability of renewable energy sources—particularly solar and small-scale hydropower—and examines the mismatch between energy supply and growing demand. The study highlights Togo’s heavy reliance on biomass and energy imports from neighbouring countries such as Ghana, Côte d’Ivoire, and Nigeria, which exacerba [...]

1154 7017

Open Access Original Research

Network Topology Similarities Across Cancer Types: Identifying Central Protein Hubs for Drug Discovery

Received: 18 June 2025;  Published: 13 October 2025;  doi: 10.21926/obm.genet.2504312

Abstract

A molecular-level understanding of cancer is essential for the development of effective therapies. Constructing protein-protein interaction (PPI) networks offers a valuable approach to identifying dysregulated driver genes and potential therapeutic targets. In this study, we modeled cancer PPI networks as metric spaces and applied mathematical and computational algorithms to analyze their structural and functional properties. Our findings reveal that these networks share a conserved architecture across different ca [...]

679 2757

Open Access Editorial

Transcutaneous Auricular Vagus Nerve Stimulation (taVNS): Precise Integration Between Neuroscience and Integrative Medicine

Received: 10 September 2025;  Published: 10 October 2025;  doi: 10.21926/obm.icm.2504043

Abstract

Transcutaneous auricular vagal nerve stimulation (taVNS) is a non-invasive method that regulates the autonomic nervous system via electrical stimulation of the auricular branch of the vagus nerve. Recent literature demonstrates that taVNS can decrease systemic inflammation, attenuate emotional disorders, modulate autonomic functions, and facilitate neural plasticity. This review examines the neurophysiological mechanisms of taVNS, including stimulation paradigms (short- and intensive, prolonged), and clinical findi [...]

2308 10209

Open Access Original Research

When the Psychological Weight of the Burden Affects the Physical Weight of Caregivers of Older Patients in a French Memory Hospital (Lille, France)

Received: 23 May 2025;  Published: 10 October 2025;  doi: 10.21926/obm.geriatr.2504328

Abstract

Caring for patients with neurocognitive disorders (NCD) can be challenging for caregivers, with the risk of malnutrition. Observational, retrospective, monocentric study carried out with patient-caregiver dyads admitted to the Memory Day Hospital of the Gerontology Center of the University Hospital of Lille over 6 months in 2023. Our objectives were to identify the socio-characteristics of caregivers who had recently experienced a variation in their weight, their degree of fatigue (using the Fatigue Numerical Ratin [...]

645 2247

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