Table of Content

Open Access Original Research

Computer-Aided Study on Metal Complexes with Benzohydrazide Schiff Base as Potential Bacterial and Fungi Inhibitors

Received: 22 October 2024;  Published: 06 March 2025;  doi: 10.21926/rpse.2501002

Abstract

The biochemical properties of metal complexes containing benzo hydrazide Schiff base have been reported by numerous researchers worldwide in various ways. In this work, the evaluation of biochemical roles of the metal complexes with benzo hydrazide Schiff base activity as anti-gram positive and gram-negative bacteria, as well as antifungal agents, were observed. The use of various techniques, including the induced fit docking methodology, the density functional theory method, and pharmacokinetics investigations wit [...]

1357 5382

Open Access Original Research

A Fuel Cell Control System for Performance Improvement under Variable Atmospheric Pressure Conditions

Received: 20 September 2024;  Published: 20 January 2025;  doi: 10.21926/rpse.2501001

Abstract

This work focuses on designing a control unit for improving Proton Exchange Membrane Fuel Cell (PEMFC) performance powering electric vehicles when operating in variable atmospheric pressure conditions, a current situation in mountainous countries with sudden changes in road altitude. The paper studies and analyzes the PEM fuel cell behavior working with hydrogen supply from a pressurized tank and oxygen input from atmospheric air supply in journeys with continuous variation of road level due to the orography. The w [...]

1514 7084

Open Access Review

Food Biodiversity Loss, Climate Change, and Malnutrition: Implications for Sustainable and Healthy Diets

Received: 01 January 2026;  Published: 09 July 2026;  doi: 10.21926/rpn.2603014

Abstract

Climate change, biodiversity loss, and malnutrition are interconnected global challenges that increasingly threaten food security, healthy diets, and environmental sustainability. Current dietary patterns characterized by high consumption of ultra-processed foods have negative environmental impacts, including increased greenhouse gas emissions, water and land use, malnutrition, and biodiversity loss. Sustainable and healthy diets that emphasize plant-based foods, minimize food waste, and promote ecosystem conservat [...]

37 137

Open Access Original Research

The Effect and Mechanisms of Risperidone and Voluntary Exercise Intervention on Hepatic Lipid Metabolism in Juvenile Female Rats

Received: 20 November 2025;  Published: 09 July 2026;  doi: 10.21926/rpn.2603013

Abstract

Risperidone is a commonly used antipsychotic drug in juveniles, but with serious metabolic side-effects. Previous evidence suggests that exercise mitigates risperidone-induced hypertriglyceridemia and adipose accumulation, yet the underlying hepatic mechanisms remain unclear. In this study, female juvenile rats were randomly assigned to four groups (n = 8/group): Vehicle + Sedentary, Risperidone (0.9 mg/kg, twice daily) + Sedentary, Vehicle + Exercise (3-hour voluntary access to a running wheel/day), and Risperidon [...]

27 123

Open Access Review

Health-Promoting Potential of Hemp (Cannabis sativa) Root Extracts: Phytochemical Composition, Biological Activities, and Nutraceutical Applications

Received: 09 April 2026;  Published: 05 July 2026;  doi: 10.21926/rpn.2603012

Abstract

Despite industrial hemp (Cannabis sativa L.) being long recognized for its diverse bioactive phytochemicals, most scientific studies have predominantly focused on aerial tissues, leaving the roots relatively underexplored. This review provides a comprehensive overview of the phytochemical architecture, biological functionalities, and nutraceutical prospects of hemp root extracts. Characterized by a unique metabolic profile featuring pentacyclic triterpenoids, phytosterols, specialized alkaloids, and neolignans, hem [...]

70 375

Open Access Research Article

Iron Demand and Regulation in Early Pregnancy: A Study of Erythropoietin, Hepcidin, and Iron Status at First Booking

Received: 21 January 2026;  Published: 24 June 2026;  doi: 10.21926/rpn.2602011

Abstract

During pregnancy, the increased demand for elemental iron makes pregnant women particularly susceptible to iron deficiency anemia. The management of iron homeostasis and erythropoiesis is controlled by hepcidin and erythropoietin. A comprehensive assessment that incorporates the stimulus, the regulatory gatekeeper (hepcidin), and the resulting iron status provides a robust, mechanistic framework for comprehending the initial disruptions in iron metabolism during pregnancy. This study aims to evaluate alterations in [...]

175 580

Open Access Review

The Role of Plant-Forward Diets in Physical Attractiveness: Integrating Facial, Olfactory, and Morphological Signals for Health Behavior Change

Received: 11 January 2026;  Published: 22 June 2026;  doi: 10.21926/rpn.2602010

Abstract

Traditional public health messaging prioritizes disease prevention, whereas individual motivations for dietary change frequently focus on appearance and social outcomes. Physical attractiveness functions as a multimodal signal, combining facial appearance, body odor, and body composition. Evolutionary models posit that such cues communicate fitness-relevant information regarding health status. This narrative review integrates empirical evidence linking plant-forward dietary patterns to facial attractiveness, body o [...]

483 2835

Open Access Review

Vegan and Plant-Based Diets in Rheumatic Diseases: A Review of Current Evidence, Mechanisms, and Perspectives

Received: 28 January 2026;  Published: 16 June 2026;  doi: 10.21926/rpn.2602009

Abstract

Plant-based diets have attracted increasing interest in the context of rheumatic diseases due to their potential anti-inflammatory, antioxidant, and immunomodulatory effects. However, there is an important conceptual distinction between a vegan diet, which completely excludes animal-derived products, and a plant-based diet, which prioritizes plant foods but may include small amounts of animal-derived foods. This differentiation is essential to understand the variability in clinical outcomes reported across studies. [...]

284 1213

Open Access Review

Role of Cereals and Pseudo-cereals in the Management of Neurodegenerative Diseases (NDDs) with a Special Reference to Alzheimer’s and Parkinson’s Disease

Received: 19 January 2026;  Published: 12 June 2026;  doi: 10.21926/rpn.2602008

Abstract

Neuro degenerative diseases involve protein aggregation that causes neural cell death or loss of neural communication that affects body balance, movement, talking, breathing, and heart function. Aggregation of proteins, like α-synuclein, are found in Parkinson’s disease (PD), while tau, amyloid-β42 and TDP-43, are aggregated in Alzheimer’s disease (AD). Besides, amyotrophic lateral sclerosis (ALS); dementia with Lewy bodies (DLB); dystrophic neuritis (DN); corticobasal degeneration (CBD); argyrophilic grain disease [...]

306 794

Open Access Review

Milk-Derived Extracellular Vesicles as Multifunctional Therapeutic Platforms in Human Health, Nutrition, and Diagnostics

Received: 06 February 2026;  Published: 09 June 2026;  doi: 10.21926/rpn.2602007

Abstract

Extracellular vesicles (EVs) are nanoscale, lipid-bilayer carriers that mediate intercellular communication by transporting proteins, lipids, and nucleic acids, thereby influencing physiological and pathological processes. This review integrates current knowledge on milk-derived and human extracellular vesicles, highlighting their multifunctional roles in therapy, diagnostics, and regenerative medicine. Milk-derived EVs (MEVs), small EVs (sEVs), and human milk EVs (hMEVs) demonstrate unique stability, biocompatibil [...]

439 1485

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