Computer-Aided Study on Metal Complexes with Benzohydrazide Schiff Base as Potential Bacterial and Fungi Inhibitors
Abstract
1357 5382
Computer-Aided Study on Metal Complexes with Benzohydrazide Schiff Base as Potential Bacterial and Fungi Inhibitorsby
Abstract
The biochemical properties of metal complexes containing benzo hydrazide Schiff base have been reported by numerous researchers worldwide in various ways. In this work, the evaluation of biochemical roles of the metal complexes with benzo hydrazide Schiff base activity as anti-gram positive and gram-negative bacteria, as well as antifungal agents, were observed. The use of various techniques, including the induced fit docking methodology, the density functional theory method, and pharmacokinetics investigations wit [...] 1357 5382 |
A Fuel Cell Control System for Performance Improvement under Variable Atmospheric Pressure ConditionsAbstract
This work focuses on designing a control unit for improving Proton Exchange Membrane Fuel Cell (PEMFC) performance powering electric vehicles when operating in variable atmospheric pressure conditions, a current situation in mountainous countries with sudden changes in road altitude. The paper studies and analyzes the PEM fuel cell behavior working with hydrogen supply from a pressurized tank and oxygen input from atmospheric air supply in journeys with continuous variation of road level due to the orography. The w [...] 1514 7084 |
Food Biodiversity Loss, Climate Change, and Malnutrition: Implications for Sustainable and Healthy Dietsby
Abstract
Climate change, biodiversity loss, and malnutrition are interconnected global challenges that increasingly threaten food security, healthy diets, and environmental sustainability. Current dietary patterns characterized by high consumption of ultra-processed foods have negative environmental impacts, including increased greenhouse gas emissions, water and land use, malnutrition, and biodiversity loss. Sustainable and healthy diets that emphasize plant-based foods, minimize food waste, and promote ecosystem conservat [...] 37 137 |
The Effect and Mechanisms of Risperidone and Voluntary Exercise Intervention on Hepatic Lipid Metabolism in Juvenile Female RatsAbstract
Risperidone is a commonly used antipsychotic drug in juveniles, but with serious metabolic side-effects. Previous evidence suggests that exercise mitigates risperidone-induced hypertriglyceridemia and adipose accumulation, yet the underlying hepatic mechanisms remain unclear. In this study, female juvenile rats were randomly assigned to four groups (n = 8/group): Vehicle + Sedentary, Risperidone (0.9 mg/kg, twice daily) + Sedentary, Vehicle + Exercise (3-hour voluntary access to a running wheel/day), and Risperidon [...] 27 123 |
Health-Promoting Potential of Hemp (Cannabis sativa) Root Extracts: Phytochemical Composition, Biological Activities, and Nutraceutical ApplicationsAbstract
Despite industrial hemp (Cannabis sativa L.) being long recognized for its diverse bioactive phytochemicals, most scientific studies have predominantly focused on aerial tissues, leaving the roots relatively underexplored. This review provides a comprehensive overview of the phytochemical architecture, biological functionalities, and nutraceutical prospects of hemp root extracts. Characterized by a unique metabolic profile featuring pentacyclic triterpenoids, phytosterols, specialized alkaloids, and neolignans, hem [...] 70 375 |
Iron Demand and Regulation in Early Pregnancy: A Study of Erythropoietin, Hepcidin, and Iron Status at First Bookingby
Abstract
During pregnancy, the increased demand for elemental iron makes pregnant women particularly susceptible to iron deficiency anemia. The management of iron homeostasis and erythropoiesis is controlled by hepcidin and erythropoietin. A comprehensive assessment that incorporates the stimulus, the regulatory gatekeeper (hepcidin), and the resulting iron status provides a robust, mechanistic framework for comprehending the initial disruptions in iron metabolism during pregnancy. This study aims to evaluate alterations in [...] 175 580 |
The Role of Plant-Forward Diets in Physical Attractiveness: Integrating Facial, Olfactory, and Morphological Signals for Health Behavior Changeby
Abstract
Traditional public health messaging prioritizes disease prevention, whereas individual motivations for dietary change frequently focus on appearance and social outcomes. Physical attractiveness functions as a multimodal signal, combining facial appearance, body odor, and body composition. Evolutionary models posit that such cues communicate fitness-relevant information regarding health status. This narrative review integrates empirical evidence linking plant-forward dietary patterns to facial attractiveness, body o [...] 483 2835 |
Vegan and Plant-Based Diets in Rheumatic Diseases: A Review of Current Evidence, Mechanisms, and PerspectivesAbstract
Plant-based diets have attracted increasing interest in the context of rheumatic diseases due to their potential anti-inflammatory, antioxidant, and immunomodulatory effects. However, there is an important conceptual distinction between a vegan diet, which completely excludes animal-derived products, and a plant-based diet, which prioritizes plant foods but may include small amounts of animal-derived foods. This differentiation is essential to understand the variability in clinical outcomes reported across studies. [...] 284 1213 |
Role of Cereals and Pseudo-cereals in the Management of Neurodegenerative Diseases (NDDs) with a Special Reference to Alzheimer’s and Parkinson’s Diseaseby
Abstract
Neuro degenerative diseases involve protein aggregation that causes neural cell death or loss of neural communication that affects body balance, movement, talking, breathing, and heart function. Aggregation of proteins, like α-synuclein, are found in Parkinson’s disease (PD), while tau, amyloid-β42 and TDP-43, are aggregated in Alzheimer’s disease (AD). Besides, amyotrophic lateral sclerosis (ALS); dementia with Lewy bodies (DLB); dystrophic neuritis (DN); corticobasal degeneration (CBD); argyrophilic grain disease [...] 306 794 |
Milk-Derived Extracellular Vesicles as Multifunctional Therapeutic Platforms in Human Health, Nutrition, and Diagnosticsby
Abstract
Extracellular vesicles (EVs) are nanoscale, lipid-bilayer carriers that mediate intercellular communication by transporting proteins, lipids, and nucleic acids, thereby influencing physiological and pathological processes. This review integrates current knowledge on milk-derived and human extracellular vesicles, highlighting their multifunctional roles in therapy, diagnostics, and regenerative medicine. Milk-derived EVs (MEVs), small EVs (sEVs), and human milk EVs (hMEVs) demonstrate unique stability, biocompatibil [...] 439 1485 |
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