OBM Transplantation (ISSN 2577-5820) is an international peer-reviewed Open Access journal published quarterly online by LIDSEN Publishing Inc., which covers all evidence-based scientific studies related to transplantation, including: transplantation procedures and the maintenance of transplanted tissues or organs; assimilation of grafted tissue and the reconstitution of removed organs or parts of organs; transplantation of heart, lung, kidney, liver, pancreatic islets and bone marrow, etc. Areas related to clinical and experimental transplantation are also of interest.
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Infections in Liver Transplantation
Yasuhiko Sugawara, MD, PhD
Associate Professor, Pediatric Surgery and Transplantation Division, Department of Surgery, Kumamoto University, 1-1-1 Honjo, Chuo-ku, Kumamoto 860-5783, Japan
Research Interests: Hepatobiliary surgery; liver transplantation
Topical Collection Information
Liver transplant is a life-saving procedure for many kinds of end-stage liver diseases. Despite of the use of protective measures such as, antimicrobial prophylaxis and vaccination, infections still represent one of the major causes of morbidity and mortality after liver transplantation. Bacteria, fungi, viruses and also parasites can cause infectious complications after liver transplantation.
In this special issue on infections in liver transplantation, submissions related to this topic are invited. Original research, quality and quantitative systematic analysis, review article, case reports pertaining on the infections in liver transplantation, in the adult or pediatric populations are welcome for submission. Topics including bacterial, viral and fungal infections are all eligible.
Publication (8 papers)
Cytomegalovirus (CMV) infection is the most common infection affecting kidney transplant recipients . CMV may be present as asymptomatic viremia or with symptoms ranging from mild to significant tissue-invasive disease [1-3]. Optimal kidney graft function and survival requires that transplant car [...]
Liver transplant is a life-saving therapy for patients with end stage liver disease and liver cancer. Liver re-transplantation cases are usually more challenging and riskier than primary surgery, they require careful consideration and larger recourse utilization. Decision making on who receives tran [...]
Bacterial infection represents a common event in the natural history of cirrhosis, especially in patients with end-stage liver disease. An episode of bacterial infection may significantly modify a patient’s outcome in the setting of liver transplantation (LT) by impairing hepatic and extrahepatic or [...]
The infectious complications before and after liver transplant (LT) are affected by the severity of liver disease and immunosuppression intensity after transplantation. Both cirrhosis and immunosuppression contribute to dysfunction of defensive mechanisms of the host. When a patient is evaluated for [...]
We report two cases of histoplasmosis in orthotopic liver transplant (OLT) recipients to illustrate the variable presentations, complications encountered during treatment, the spectrum of diagnostic modalities, and case outcomes. Case 1 describes the insidious presentation of presumed gastrointestin [...]
Primary biliary cholangitis (PBC) and primary sclerosing cholangitis (PSC) are idiopathic and progressive autoimmune hepatobiliary disorders that lead to liver failure and a need for liver transplantation in a proportion of individuals with poorly controlled disease. It is currently thought that an [...]
Toxoplasmosis in liver transplantation (LT) is uncommon, especially in the current era of universal prophylaxis with trimethoprim-sulfamethoxazole (TMP-SMX) for Pneumocystis jirovecii pneumonia (PJP). Here we present a case of a 55-year-old woman LT recipient, on dapsone or PJP prophylaxis due to su [...]
Background: Graft site candidiasis is a serious complication after solid organ transplantation, often presenting as invasive arteritis leading to graft loss or even death.
Case Report: We report a case of anastomotic site candidiasis leading to arterial rupture and death at postoperative day 10 with [...]