OBM Geriatrics is an Open Access journal published quarterly online by LIDSEN Publishing Inc. The journal takes the premise that innovative approaches – including gene therapy, cell therapy, and epigenetic modulation – will result in clinical interventions that alter the fundamental pathology and the clinical course of age-related human diseases. We will give strong preference to papers that emphasize an alteration (or a potential alteration) in the fundamental disease course of Alzheimer’s disease, vascular aging diseases, osteoarthritis, osteoporosis, skin aging, immune senescence, and other age-related diseases.
Geriatric medicine is now entering a unique point in history, where the focus will no longer be on palliative, ameliorative, or social aspects of care for age-related disease, but will be capable of stopping, preventing, and reversing major disease constellations that have heretofore been entirely resistant to interventions based on “small molecular” pharmacological approaches. With the changing emphasis from genetic to epigenetic understandings of pathology (including telomere biology), with the use of gene delivery systems (including viral delivery systems), and with the use of cell-based therapies (including stem cell therapies), a fatalistic view of age-related disease is no longer a reasonable clinical default nor an appropriate clinical research paradigm.
Precedence will be given to papers describing fundamental interventions, including interventions that affect cell senescence, patterns of gene expression, telomere biology, stem cell biology, and other innovative, 21st century interventions, especially if the focus is on clinical applications, ongoing clinical trials, or animal trials preparatory to phase 1 human clinical trials.
Papers must be clear and concise, but detailed data is strongly encouraged. The journal publishes research articles, reviews, communications and technical notes. There is no restriction on the length of the papers and we encourage scientists to publish their results in as much detail as possible.
Archiving: full-text archived in CLOCKSS.
Publication Speed (median values for papers published in 2022): Submission to First Decision: 5 weeks; Submission to Acceptance: 14 weeks; Acceptance to Publication: 11 days (1-2 days of FREE language polishing included)
Depression and Aging: Role of Social Support
Submission Deadline: August 30, 2019 (Open) Submit Now
Adjunct Professor, Department of Health and Behavior Studies, Program in Health Education, Teachers College and School of Health and Behavioral Sciences, Columbia University, New York, NY, USA; Department of Health, Physical Education & Gerontological Studies and Services, York College, City University of New York, New York, NY, USA.
Research Interests: Osteoporosis; osteoarthritis; knee osteoarthritis; falls prevention; depression; aging
About This Topic
Geriatric depression is a mental and emotional disorder affecting older adults. Feelings of sadness and occasional “blue” moods are normal. Depression in older adults can reduce quality of life, and it increases risk of suicide. However, social support plays an important role in prevention and treating depression.
Articles of any genre concerning the importance of social support in preventing and treating depression in the context of successful aging, obesity, chronic pain and chronic disease would be in order."
Manuscripts should be submitted online at http://www.lidsen.com/account-login by registering and logging in to this website. Once you are registered, click here to go to the submission form. Papers will be published continuously (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles, case reports and communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website. Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are refereed through a peer-review process.
Received: 30 August 2019; Published: 02 January 2020; doi: 10.21926/obm.geriatr.2001096
Social isolation and social disconnectedness have resulted in some older adults ending their lives by suicide; therefore, improving social connectedness has become an integral part of suicide prevention programmes. The purpose of this literature review was to assess the impact of social connectedness interventions for preventing suicide in [...]
Received: 06 August 2019; Published: 04 December 2019; doi: 10.21926/obm.geriatr.1904091
The prevalence of Late-life Depression (LLD) is estimated between 10 and 15 % and therefore LLD is a considerable world-wide problem. The psychopathology is not substantially different from that of depressive episodes in young adults, but somatic complaints in combination of end-of-life perspective leave an imprint on emotional experience [...]
Received: 14 August 2019; Published: 25 November 2019; doi: 10.21926/obm.geriatr.1904088
Louise H., Ph.D was referred to me by her long-term primary care physician (PCP) who was certain that his patient was seriously depressed and in need of medication and possibly psychotherapy. My own assessment, in consultation with a neurologist, was that Louise’s problems with coping were primarily neurological, and that her issues were [...]
Facilitation of Social Support through Negative Allosteric Modulation of α5-Associated GABAA Receptors: A Novel Mechanism for the Treatment of Depression, Agitation, and Aggression in the Elderly
by Jeffrey M. Witkin , Lalit K. Golani , Rok Cerne , Md. Toufiqur Rahman , Guanguan Li , Michael M. Poe , James M. Cook and Jodi L. Smith
Received: 05 May 2019; Published: 26 August 2019; doi: 10.21926/obm.geriatr.1903073
Major depressive disorder is a highly-prevalent and debilitating disorder in the aged population. Recent and accumulating clinical evidence suggests a key role for social support in helping to mitigate depression. Preclinical data are reviewed that indicate that selective negative allosteric modulation of α5-associated GABAA [...]
Differential Effects of Social Network on Health in Later Life and the Moderating Role of Depression
Received: 23 March 2019; Published: 12 August 2019; doi: 10.21926/obm.geriatr.1903067
Background: We studied the differential effects of social network characteristics on limitations with activities (LWA) and quality of life (QOL) among older adults, and the moderating role of depression. Methods: Data from two consecutive waves of the Survey of Health, Aging and Retirement in Europe (SHARE) were examined. Results: Emotional [...]
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