Table of Contents

Open Access

ISSN 2638-1311

OBM Geriatrics , Volume 5 , Issue 4 (2021)

Pages: 107

Published: March 2022

(This book is a printed edition that was published in OBM Geriatrics)

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Cover story: Despite significant improvements in prevention and treatment, atherosclerosis-related diseases remain the leading cause of mortality in developed nations. FT-IR spectroscopy, a noninvasive method to identify atherosclerosis, showed up that oxidative stress leads to lipid peroxidation, fibril formation, AGEs and calcium accumulation while smoking and professional toxic metals alter the ROS formation. View this paper.

Volume 5,Issue 4

Open Access Original Research

Adjustment for Covariates of Major Depressive Episodes among Men and Women Aged 65 Years Old and Older

Received: 17 August 2021;  Published: 22 December 2021;  doi: 10.21926/obm.geriatr.2104185


The current study aimed to examine if sex can significantly predict risk for lifetime major depressive episodes among adults aged 65 and older with and without adjustment for covariate variables of race, education, marital status, health, and poverty. Secondary data was obtained from the National Su [...]

Open Access Research Article

The Safety of Oral Telomerase Activator in UV-Induced Skin Cancer with A Review of Telomerase in Aging and Skin Carcinogenesis

Received: 29 July 2021;  Published: 13 December 2021;  doi: 10.21926/obm.geriatr.2104184


The supplement telomerase activator TA-65 (purified from Astragalus membranaceus) has been shown to retard cellular senescence, boost the aging immune system, and retard age-related symptoms. Lengthened telomeres retard aging, but because cancers often maintain longe [...]

Open Access Original Research

Cisplatin-Based Neoadjuvant Chemotherapy for Elderly Patients with Muscle-Invasive Bladder Cancer: Is It Feasible?

Received: 23 July 2021;  Published: 08 November 2021;  doi: 10.21926/obm.geriatr.2104183


Cisplatin-based neoadjuvant chemotherapy (C-NAC) has been the standard of care in localized muscle-invasive bladder cancer (MIBC). However, the feasibility and benefit of C-NAC in elderly patients remain uncertain since this population has always been underrepresented in pivotal trials a [...]

Open Access Original Research

Men's Bones Matter Too, a Cross Sectional Study Examining Bone Health among Men with Intellectual Disability in Ireland.

Received: 23 June 2021;  Published: 08 November 2021;  doi: 10.21926/obm.geriatr.2104182


Globally between 30-40% of all osteoporotic fractures occur among men, with a quarter of all hip fractures, the most serious complication of osteoporosis, occurring in men. Among men of 50 years of age or older, osteoporotic fracture risk reaches an alarming 20%. What is of great concern [...]

Open Access Review

An Overview of Osteoporosis Management

Received: 28 June 2021;  Published: 19 October 2021;  doi: 10.21926/obm.geriatr.2104181


Osteoporosis is one of the most common disorders around the world. Osteoporotic fracture especially hip fracture are associated with an increased mortality rate in elders. However, elders with osteoporosis or at high risk of fractures remain largely underdiagnosed and undertreated. The s [...]

Open Access Research Article

Study of the Development of Carotid Artery Atherosclerosis upon Oxidative Stress using Infrared Spectroscopy and Scanning Electron Microscopy

Received: 07 March 2021;  Published: 12 October 2021;  doi: 10.21926/obm.geriatr.2104180


In the present study, Fourier-transform infrared (FTIR) spectroscopy and Scanning Electron Microscopy (SEM) were used to investigate the formation and development of carotid artery atherosclerosis. The FTIR spectra showed that with the progression of atheromatic plaque formation, the col [...]