Table of Content

Open Access Perspective

Therapeutic Carbohydrate Reduction for Lipedema: Guidelines for a Patient-Centered, Holistic Approach

Received: 31 May 2025;  Published: 03 September 2025;  doi: 10.21926/rpn.2503019

Abstract

Lipedema is a chronic, often misdiagnosed disease characterized by painful, disproportionate fat accumulation in the extremities. Commonly mistaken for obesity or lymphedema, lipedema primarily affects women and has long been thought to be resistant to dietary intervention, a belief originating from its initial description by Allen and Hines at the Mayo Clinic in 1940. However, emerging research challenges this notion, revealing that individuals with lipedema often respond positively to therapeutic carbohydrate (CH [...]

3113 27430

Open Access Review

Engaging with an Industrial Pandemic: Drivers of and Responses to the Expansion of Ultra-Processed Foods in East and Southern Africa

Received: 14 January 2025;  Published: 29 August 2025;  doi: 10.21926/rpn.2503018

Abstract

Intensified marketing and expanding consumption of ultra-processed foods (UPFs) that contain high sugar, salt, trans-fats and other additives and sugar sweetened beverages in Sub-Saharan Africa (SSA) are associated with rising obesogenic environments and non-communicable diseases, termed by some an ‘industrial pandemic’ due to its commercial drivers and cross border nature. This review paper addresses the question of how far SSA, positioned at an early point of a rising wave, is controlling this growing health chal [...]

1145 4702

Open Access Interview

An Interview with Prof. Rosita Gabbianelli

Received: 24 August 2025;  Published: 27 August 2025;  doi: 10.21926/rpn.2503017

Abstract

An Interview with Prof. Rosita Gabbianelli

450 2204

Open Access Review

Physiological Impact of Milk on Multiple Health Outcomes in Human

Received: 19 December 2024;  Published: 20 August 2025;  doi: 10.21926/rpn.2503016

Abstract

Milk is best known as a nutrient-rich fluid produced by the mammary glands of mammals, designed primarily to feed young. In the human diet, cow milk is most prevalent, but milk of other mammals and plant milk are common too. This study aims to investigate milk's nutritional value in various age groups and review opposing evidence of its effect on cardiovascular diseases in adults. It is a literature-based strategy to synthesize information from observational and meta-analytic studies. The milk content—macronutrient [...]

1847 9316

Open Access Original Research

Germination-Induced Starch Influence on Structural Characteristics of Water-Soluble Extracts from Purple Pericarp Creole Corn

Received: 14 October 2024;  Published: 28 July 2025;  doi: 10.21926/rpn.2503015

Abstract

Germination is a viable, cost-effective, and environmentally friendly biotechnological process that enhances the industrial applications of cereals. This study evaluated the impact of germination (86 hours at 30°C) on soluble solids, proximate composition, and total phenolic compounds (TPC) in water-soluble extracts. It also included imaging analyses using scanning electron microscopy (SEM), X-ray diffraction (XRD), apparent amylose content, and starch pasting properties of purple pericarp Creole corn (PPCC) fr [...]

882 3957

Open Access Original Research

Attenuation of Blood Glucose by the Ketone Monoester (R)-3-betahydroxybutyrate Glyceride in Healthy Male Sprague Dawley Rats in Response to a Standard Oral Glucose Tolerance Test

Received: 31 January 2025;  Published: 25 July 2025;  doi: 10.21926/rpn.2503014

Abstract

Efficient glucose uptake by peripheral tissue is important for individuals who desire to maintain optimal wellbeing. Various methods to regulate postprandial blood glucose have been reported in the research literature, however, few have examined the effect of ketone esters on blood glucose levels. The present study evaluated blood glucose following the administration of an oral glucose tolerance test, with and without ketone esters delivered at two different dosages, in a sample of healthy Sprague-Dawley rats. We h [...]

967 5158

Open Access Research Article

Physicochemical Characterization of Fresh and Powdered Tomato in Arba Minch, Ethiopia

Received: 07 January 2025;  Published: 02 June 2025;  doi: 10.21926/rpn.2502013

Abstract

Tomato (Solanum lycopersicum L.) is the largest vegetable crop produced and consumed in the world. Tomatoes are a top source of Vitamin A and C, contain more dietary fibre, beta-carotene, iron, lycopene, magnesium, niacin, potassium, phosphorus, riboflavin, and thiamine. Tomatoes have a limited shelf life in ambient conditions and are highly perishable. It creates glut during the production season and becomes scanty during the off-season. Short shelf life, coupled with inadequate processing facilities results in he [...]

1356 7038

Open Access Original Research

The Importance of Specialized Inpatient Medical Stabilization for Weight Restoration of Individuals with Extreme Eating Disorders

Received: 19 December 2024;  Published: 23 May 2025;  doi: 10.21926/rpn.2502012

Abstract

Inpatient care is a significant contributor to the health-care costs associated with the treatment of individuals with eating disorders (EDs). This study seeks to better understand the treatment outcomes of individuals with extreme EDs requiring inpatient medical stabilization at specialized medical versus nonspecialized medical units. Patients transferred via air ambulance to ACUTE Center for Eating Disorders and Severe Malnutrition (specialized care) from an outside hospital (nonspecialized care) between January [...]

867 7525

Open Access Original Research

The Contribution of Dietary Fatty Acids to Prediction of All-Cause Mortality in a Cohort of Middle-Aged Men Followed-Up for 61 Years Until Extinction

Received: 09 November 2024;  Published: 19 May 2025;  doi: 10.21926/rpn.2502011

Abstract

To describe the contribution of three classes of dietary fatty acids to all-cause mortality and age at death among middle-aged men followed up for 61 years until extinction. The cohort comprised 1712 men aged 40-59 years at entry examination in 1960, belonging to the Italian Rural Areas of the Seven Countries Study of Cardiovascular Diseases. A dietary survey allowed to estimate dietary fatty acids [saturated (SAFA), mono-unsaturated (MUFA), poly-unsaturated (PUFA) and their ratios (M/S, P/S)] that were fed as poss [...]

872 3798

Open Access Review

Exclusive Enteral Nutrition as an Effective Treatment in Inflammatory Bowel Disease

Received: 17 November 2024;  Published: 13 May 2025;  doi: 10.21926/rpn.2502010

Abstract

In recent years, the incidence of Inflammatory Bowel Disease (IBD) has risen significantly in the Western population, pointing toward the potential influence of environmental and dietary factors. In order to explain this, some research on nutritional therapy identifies exclusive enteral nutrition (EEN) as a highly effective approach for managing IBD in children. This treatment achieves high remission rates; more specifically, some clinical trials have reported remission rates from 70% to 100%. EEN not only facilita [...]

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