by Yang Xu  , Eng Hwa Wong  , Rusli Bin Nordin  , Abdul Kareem Meera Mohaideen  , Benjamin Samraj Prakash Earnest  and Yin How Wong

Received: 11 July 2023;  Published: 16 January 2024;  doi: 10.21926/obm.neurobiol.2401209

Stroke is the second and third leading cause of death and disability, respectively, all over the world. It seriously affects patients' lives and brings huge burdens to their families. Ischemic stroke accounts for most of the stroke cases. In the absence of any effective treatment, prevention measures through controlling the risk factors for ischemic stroke become crucial. While uric acid has been reported as an essential risk factor for ischemic stroke, researchers hold inconsistent views regarding the specific ass [...]

by Naylya Djumaeva  , Gulnara Akhundjanova  , Leyla Djumaeva  and Dilbar Urunova

Received: 08 October 2023;  Published: 16 January 2024;  doi: 10.21926/obm.icm.2401010

Long COVID syndrome resulting from SARS-CoV-2 infection has a prevalence of 10%-35% in the population. Numerous studies of the disease are currently being conducted concerning the manifestations of long COVID syndrome; however, there are no data on the use of electroacupuncture diagnosis (EAV) and medicament testing (MT) in assessing this condition. The purpose of the study was to study the possibilities of diagnosing EAV to determine changes in the electrodermal activity of acupuncture points of the meridian test [...]

by Loree Cook-Daniels

Received: 16 July 2023;  Published: 15 January 2024;  doi: 10.21926/obm.geriatr.2401266

Lesbian, gay, bisexual, transgender, and queer (LGBTQ+) elders are vulnerable to both the “usual” types of elder abuse (physical, sexual, emotional, and financial abuse, along with neglect), and with abuse that is specific to the context and history of LGBTQ+ elders. Training for adult protective services, long-term care ombudsmen, and other professionals who work with abused elders therefore should include information and skill-building in responding to this population. Research into effective training about LGBTQ [...]

by Joana Sousa

Received: 15 May 2023;  Published: 15 January 2024;  doi: 10.21926/aeer.2401003

The climate change and the social crisis launched the basis for the policy discussion about future trajectories of development and sustainability. Innovation policies are expected to promote the transformation of complex socio-technical systems and call for fundamentally different societal production and consumption patterns. This is strictly associated with energy systems and energy policies. A policy framework was conceptualized considering three levels approach: the policy shape at the micro level, the policy co [...]

by Shibani Kanungo  , Samantha A. Vergano  , Thomas Clark  , Rami Madani  , Melissa Schott  , Kira Couch  , Rubie Villela  and Natalie White

Received: 07 September 2023;  Published: 12 January 2024;  doi: 10.21926/obm.genet.2401210

Krabbe disease (KD), a severe neurodegenerative disorder, has been controversial in the space of newborn screening (NBS) in the United States. Families continue to advocate for the addition of KD to the Recommended Uniform Screening Panel (RUSP) after being declined for the second time in February 2023. Even with significant progress in KD screening tests, uncertainty about the phenotypic presentations, and effectiveness of hematopoietic stem cell transplant (HSCT) seems to have impeded the addition of this conditi [...]

by Aaryan Gupta  , Arpita Roy  , Kirtanjot Kaur  , Sarvesh Rustagi  , Sumira Malik  and Soumya Pandit

Received: 08 November 2023;  Published: 11 January 2024;  doi: 10.21926/obm.neurobiol.2401208

In the last decade, development in nanotechnology has been used intensively. By studying nanotechnology and nanomaterials, we can generate excellent responses in healthcare related to neurological disorders. It also includes easy diagnosis of diseases in their early stages, delivery of genes, and many more. Neurological disorders are one of the most sensitive topics. Therefore, nanomaterials promise to treat neurological disorders as they are highly efficient. Nanomaterials will significantly expand our knowledge o [...]

by James David Adams

Received: 22 August 2023;  Published: 11 January 2024;  doi: 10.21926/obm.icm.2401009

Many websites are dedicated to educating the public about chronic pain and its management. The majority of these websites say there is no cure for chronic pain, but encourage patients to try exercise, diet, stress reduction and other techniques to decrease the severity of chronic pain. Patients are also taught to use oral or injected drugs to treat their chronic pain. This can be dangerous and leads to adverse events and death in some patients. The majority of these websites teach patients that chronic pain comes f [...]

by Stephanie Bryan  and Maryellen Hamilton

Received: 20 October 2023;  Published: 10 January 2024;  doi: 10.21926/obm.icm.2401008

This paper provides an overview of gratitude as a concept and as a mind-body-spirit practice, impacting health and human functioning throughout the lifespan, that can be integrated into daily life to great benefit at no cost. Current society is rife with increases in stress, anxiety, depression, lifestyle-related diseases, and social isolation. The practice of gratitude and its interrelated pro-social, health-enhancing, resilience-building effects suggest that promoting gratitude from childhood through adulthood ma [...]

by Yulia Aleksandrova  , Alexey Semakov  , Dmitry Tsypyshev  , Kirill Chaprov  , Sergey Klochkov  and Margarita Neganova

Received: 23 August 2023;  Published: 09 January 2024;  doi: 10.21926/obm.neurobiol.2401207

Here, we report the results of an investigation of the neuroprotective effects of securinine with tryptamine conjugate-allomargaritarine (2b), previously selected as the leading compound among a wide range of natural derivatives. 2b was synthesized from securinine using various Lewis acids as catalysts. In addition to the antioxidant and cytoprotective properties previously shown for 2b, in this work, in vitro analysis of the biological activity of the compound demonstrated that this conjugate is also able to influ [...]

by Charlotte Grégoire  , Alexandra Paye  and Audrey Vanhaudenhuyse

Received: 16 October 2023;  Published: 09 January 2024;  doi: 10.21926/obm.icm.2401007

Self-compassion consists of an attitude of self-support and self-benevolence. In the general population, increased self-compassion has been associated with well-being and decreased psychopathology. In oncology, higher self-compassion has also been linked with various benefits, such as lower emotional distress, fatigue, body-image disturbances, and sleep difficulties. Self-compassion also seems to foster treatment adherence. Various interventions based on self-compassion have recently been designed and tested in dif [...]