by Elio Rossi  , Marco Picchi  , Marialessandra Panozzo  and Linda Nurra

Received: 01 November 2018;  Published: 20 June 2019;  doi: 10.21926/obm.icm.1902038

Aim: To study the effect of homeopathic treatment on adult patients with atopic diseases visited at the Homeopathic Clinic of Lucca (Italy) and long-term evolution of the disease over approximately an 8-year period. Materials and Methods: Data derive from an observational longitudinal study carried out on 563 atopic adult patients who were consecutively visited from 1998 to 2017; 202 (35.9%) suffered from atopic dermatitis, 204 (36.2%) from allergic rhinitis, and 157 (27.9%) from asthma. Moreover, a long-term study [...]

by Ron Dolgin  and Matthew J. Davis

Received: 20 March 2019;  Published: 18 June 2019;  doi: 10.21926/obm.icm.1902037

Integration of behavioral health consultants and specialists into medical settings has accelerated the development of evidenced-based practices for an array of problems and concerns common to behavioral medicine. Though these treatments have shown to be beneficial for those that engage in protocols, attrition remains high. With an emphasis in directed problem solving and skill building, many brief treatments leave little room for compassion, validation, and understanding. This article explores this trend and advoca [...]

by Hong Chee Chew  , Ling Gao  , Jeanette E. Villaneuva  , Aoife Doyle  , Mark Hicks  , Andrew Jabbour  , Kumud K. Dhital  and Peter S. Macdonald

Received: 09 March 2019;  Published: 18 June 2019;  doi: 10.21926/obm.transplant.1902067

Background: Normothermic machine perfusion (NMP) utilises 1.2-1.5L of donor blood (DB) with a target perfusate haematocrit of 25% to reanimate the donor heart. Limitations to current practise include small donor size and donor anaemia which can impact on the recovery of these hearts. Furthermore, in donation after circulatory death (DCD), blood collection may delay delivery of preservation solutions resulting in longer warm ischaemic times for the heart and other organs. Banked blood (BB) is a potential alternative [...]

by Joseph S. D'Arrigo

Received: 27 December 2018;  Published: 17 June 2019;  doi: 10.21926/obm.geriatr.1902057

Much evidence has been published which indicates that microvascular endothelial dysfunction, due to cerebrovascular risk factors (e.g., atherosclerosis, hypertension, obesity, diabetes, smoking, aging), precedes cognitive decline in Alzheimer's disease and contributes to its pathogenesis. By incorporating appropriate drug(s) into biomimetic (lipid cubic phase) nanocarriers, one obtains a multitasking combination therapeutic which targets certain cell-surface scavenger receptors, and crosses the blood-brain barrier [...]

by Michael Chapman  , Jennifer Philip  and Paul Komesaroff

Received: 20 December 2018;  Published: 17 June 2019;  doi: 10.21926/obm.geriatr.1902056

Alzheimer’s Disease is increasingly seen as the major health problem in developed countries supplanting cancer and heart disease. The terror with which we respond to dementia, is grounded in a view of dementia as a monstrous descent, ambushing our healthy ageing through an incursion of pathology. The pervasiveness of this view can mean that other perspectives and even the views of those most touched by the challenges of dementia remain unheard. Part of the cultural conversation around dementia is informed by [...]

by Katerina G. Oikonomou  and Sarah Taimur

Received: 14 February 2019;  Published: 17 June 2019;  doi: 10.21926/obm.transplant.1902066

In non-endemic regions of the world, human T-cell lymphotropic virus type-1 (HTLV-1) is an uncommon pathogen in the transplant host, but can be associated with significant morbidity and mortality. Careful assessment for risk factors, targeted screening and heightened awareness of the clinical presentation of HTLV-1 associated disease is necessary for timely recognition and management in the transplant host. The use of antiretroviral agents in the management of symptomatic disease due to HTLV-1 remains controversial [...]

by Kurt Grüngreiff  , Thomas Gottstein  and Dirk Reinhold

Received: 15 March 2019;  Published: 13 June 2019;  doi: 10.21926/obm.hg.1902023

Acute and in particular chronic liver disease of viral, alcoholic and non-alcoholic genesis is a large, often unnoticed health hazard around the world. It can lead to cirrhosis and hepatocellular carcinoma (HCC) in the course of decades. Liver fibrosis, conversion of functional parenchyma to connective tissue (scar tissue) as a consequence of chronic liver damage, is a connecting pathogenic process in all chronic liver diseases. Zinc is an essential micronutrient in human health, playing a fundamental role in cellu [...]

by Pras Ramluggun  and Sanj Nathoo

Received: 07 March 2019;  Published: 13 June 2019;  doi: 10.21926/obm.icm.1902036

The evolving, dynamic and challenging healthcare landscape requires that the art and science of nursing equip preregistration nursing students with the knowledge and skills to positively respond to these changes. Central to these students’ ability to demonstrate competence in the fundamentals of nursing care are core nursing attributes to meaningfully engage and attend to patients’ in delivering compassionate care and meeting their needs. The literature identifies the process of delivering compassionate care as a h [...]

by Dietmar Payrhuber  , Piero Sangaletti  and Josef Muehlmann

Received: 10 May 2018;  Published: 10 June 2019;  doi: 10.21926/obm.icm.1902035

(1) Background: The article provides insight into the mode of the immune system acting hierarchically when administering potentized remedies. Occasionally, this can be best seen in severe cases as available with cancer. (2) Methods: The careful anamnesis and subsequent prescription is based on Jan Scholten’s hierarchic classification of homeopathic mineral remedies. (3) Results: In such cases we find syndrome shifts of symptoms shifting from vital to less vital organs, from inside outside and from up downwards, e [...]

by Sheila Krishnan  , Chadi Hage  , Raymond Coakley  , David van Duin  and Leonard Jason Lobo

Received: 18 February 2019;  Published: 10 June 2019;  doi: 10.21926/obm.transplant.1902065

Lung transplant recipients are at greater risk of respiratory viral infections as compared to other solid organ transplant recipients due to constant exposure of the allograft to the external environment. There are no standardized methods for surveillance, prevention, or treatment of these infections despite their association with increased morbidity and mortality. Various studies have linked respiratory viral infections with acute cellular rejection and chronic allograft dysfunction, and emerging data indicates a [...]