by Pari Muradova

Received: 24 June 2022;  Published: 26 September 2022;  doi: 10.21926/cr.2203030

In this study, we prepared a fine-grained, aluminum-reinforced alumina support matrix of the active mass of catalysts, which showed activity in heterogeneous catalytic reactions stimulated by electromagnetic radiation in the microwave range. The support absorbed microwave radiation of 2.45 GHz. We compared the textural characteristics of samples of Al/Al2O3 supports obtained by conventional heat treatment to those synthesized by heat treatment in a microwave field. We found several advantages of heat treating poten [...]

by OBM Neurobiology Editorial Office

Received: 22 September 2022;  Published: 26 September 2022;  doi: 10.21926/obm.neurobiol.2203136

by Elaine Beaumont  , Chris Irons  and Sue McAndrew

Received: 25 May 2022;  Published: 26 September 2022;  doi: 10.21926/obm.icm.2203045

Self-guided, smartphone apps may be helpful in reducing symptoms associated with psychological distress and may boost wellbeing, and levels of compassion. To our knowledge this is the first study to examine the impact a 28-day app based on Compassion Focused Therapy and Compassionate Mind Training has on participant’s levels of compassion, wellbeing, and self-criticism. The Self-Compassion App includes exercises, meditations, quotes, a daily wisdom, and audios, all of which aim to help individuals develop com [...]

by Emory Ryan  , Tiffany Jong  and Ellen Sidransky

Received: 20 July 2022;  Published: 26 September 2022;  doi: 10.21926/obm.genet.2203165

Gaucher disease (GD) is one of the most common lysosomal storage disorders resulting from biallelic mutations in the GBA1 gene, causing a dysfunction of the lysosomal hydrolase, glucocerebrosidase (acid-β-glucosidase; E.C 3.2.1.45). Clinical manifestations are heterogenous and can include splenomegaly, anemia, and neurological impairments in the case of neuronopathic Gaucher disease types 2 and 3. Newborn screening, arguably the most important public health initiative to date, has been regularly conducted on n [...]

by Anna A. Pendina  , Mikhail I. Krapivin  , Irina D. Mekina  , Irina V. Aleksandrova  , Yanina M. Sagurova  , Evgeniia M. Komarova  , Mariia A. Ishchuk  , Andrei V. Tikhonov  , Olesya N. Bespalova  , Alexander M. Gzgzyan  , Igor Yu. Kogan  and Olga A. Efimova

Received: 13 May 2022;  Published: 23 September 2022;  doi: 10.21926/obm.genet.2203164

This paper suggests an approach for the use of a single paucicellular histological sample to investigate two characteristics indicative of the cell’s functional potential: 1) the content of telomerase reverse transcriptase (TERT) and 2) the telomere length. An algorithm has been suggested for the successive detection of the catalytic telomerase subunit with immunohistochemical staining and assessment of telomere length with Q-FISH on the same set of cells. The described approach uses three incontestable advantages [...]

by Sergey Yu. Udovichenko  , Alexander D. Pisarev  , Alexander N. Busygin  , Abdulla H. Ebrahim  , Andrey N. Bobylev  and Alexey A. Gubin

Received: 14 June 2022;  Published: 22 September 2022;  doi: 10.21926/obm.neurobiol.2203134

In the present study, we present the results of the modeling of incoming information processing in a neuroprocessor that implements a biomorphic spiking neural network with numerous neurons and trainable synaptic connections between them. Physico-mathematical models of processes of encoding information into biomorphic pulses and their decoding following a neural block into a binary code were developed as well as models of the process of routing the output pulses of neurons by the logic matrix to the synapses of oth [...]

by Kuldeep Saini  , Vinay Mohan Pathak  , Arpit Tyagi  and Rani Gupta

Received: 11 June 2022;  Published: 22 September 2022;  doi: 10.21926/cr.2203029

Cyclodextrin glycosyltransferase (CGTase) is a multifunctional enzyme that hydrolyzes the α-glycosidic bond between two sugar molecules and synthesizes cyclodextrins (CDs) and other transglycosylation products. It is a ubiquitously present extracellular enzyme that offers the CGTase-producing organism the sole right onto starch substrates over other microbes. The present review provides a brief account of diversity among CGTase-producing microbes, CGTase production in different heterologous hosts (wherein ext [...]

by Kelly Swing  , Jaime Chaves  , Stella de la Torre  , Luis Sempértegui  , Alex Hearn  , Andrea Encalada  , Esteban Suárez  and Gonzalo Rivas

Received: 30 March 2022;  Published: 22 September 2022;  doi: 10.21926/aeer.2203035

The rights of nature have been widely discussed at a philosophical level for a long time, but examples of its practical application are quite rare. Ecuador is the first country to incorporate this concept into its constitutional foundation and put the theory into practice. However, implementing entirely justifiable rights of nature is hindered by factors, such as economic considerations, legal interpretations, cultural norms, political will, and disproportionate perspectives of “the greater good”. After getting opp [...]

by Divya Taneja  , Madhumita Sadhukhan  , Padmalaya Rath  , Manas R Sarangi  , Renu Mittal  , Akshaya Kumar Prusty  , Deepthi Gilla  , Ashish Shivadikar  , Birendra Rawat  , Ravi Kumar Sadarla  , Gurudev Choubey  , Nidhi Mahajan  , Renu Bala  , Neha Kalra  , Anupam Mukherjee  , Anil Khurana  and Raj K. Manchanda

Received: 12 August 2022;  Published: 21 September 2022;  doi: 10.21926/obm.icm.2203044

Patients with psoriasis commonly opt for homeopathic treatment. However, no study has assessed the response to homeopathic treatment by using standardized disease-specific scales, and the findings are based on clinical assessments only. The objective of this study was to evaluate the response to the individualized homeopathic treatment of psoriasis with respect to changes in disease severity and quality of life based on Psoriasis Area and Severity Index (PASI) and Psoriasis Disability Index (PDI) scales, respective [...]

by Le Thanh Mai Pham  , Kai Deng  , Trent R. Northen  , Steven W. Singer  , Paul D. Adams  , Blake A. Simmons  and Kenneth L. Sale

Received: 26 July 2022;  Published: 20 September 2022;  doi: 10.21926/cr.2203028

Lignin is the most abundant renewable source of aromatics on earth, and conversion of it to chemicals and fuels is needed to build an economically viable renewable biofuels industry. Biological routes to converting lignin to fuels and chemicals involve depolymerizing lignin using lignin-degrading enzymes that catalyze the breaking of ether and carbon-carbon bonds in the phenolic and non-phenolic subunits of lignin. Laccases are a crucial class of lignin-degrading enzymes and are copper-containing enzymes capable of [...]