by Adriano Zamperini  , Antonella Pittella  , Cristina Rizzo  , Giulia Marangon  , Erika Iacona  and Ines Testoni

Received: 24 July 2022;  Published: 10 March 2023;  doi: 10.21926/obm.neurobiol.2301162

The COVID-19 pandemic has drastically changed our daily lives. One of the sectors most affected was tourism and travel – and, more specifically, cruises, given the prolonged time passengers spend with others within the small spaces of the cruise ship. While finding well-organised entertainment opportunities on cruises is possible, emergency conditions may cause panic. On such occasions, reactions can be highly stressful or even traumatic. This research explores the events and emotions experienced by passengers duri [...]

by Michael Joseph Diaz  , Kevin Thomas Root  , Alice Beneke  , Yordan Penev  and Brandon Lucke-Wold

Received: 07 October 2022;  Published: 06 March 2023;  doi: 10.21926/obm.neurobiol.2301161

Traumatic brain injury (TBI) is a significant source of brain deficit and death among neurosurgical patients, with limited prospects for functional recovery in the cases of moderate-to-severe injury. Until now, the relevant body of literature on TBI intervention has focused on first-line, invasive treatment options (namely craniectomy and hematoma evacuation) with underwhelming focus on non-invasive therapies following surgical stabilization. Recent advances in our understanding of the impaired brain have encourage [...]

by Frank M. Mezzacappa  , Caroline Davidson  and Michele R. Aizenberg

Received: 22 February 2022;  Published: 03 March 2023;  doi: 10.21926/obm.neurobiol.2301160

Glioblastoma (GBM) is malignant, primary intracranial neoplasm associated with poor outcomes. Maximal, safe cytoreduction remains an important component of effective treatment for patients with this disease; however, some patients are not candidates for resection due to comorbid status, tumor location, or other factors. In this review, we aimed to describe minimally invasive surgical techniques that are emerging as important tools for improving safety and efficiency in GBM cytoreduction, including for patients with [...]

by Ellen Kuo  , Esther Belogolovsky  , Sarah Fracci  , Amy Wozniak  , Marina Feffer  , Rachel Klauber  , Theodote K. Pontikes  and Edwin Meresh

Received: 03 October 2022;  Published: 02 March 2023;  doi: 10.21926/obm.neurobiol.2301159

The Coronavirus Disease (COVID-19) pandemic has contributed to a co-occurring psychiatric epidemic. Children and adolescents have been particularly impacted, with disruptions in continuity of learning and healthcare. Psychological stressors such as fear of infection, boredom, decreased socialization, supply shortages, and incomplete information have contributed to low mood, irritability, insomnia, and emotional exhaustion. Our study contributes to this research by quantifying the devastating psychiatric toll that t [...]

by Isabella Zuccaroli  , Brandon Lucke-Wold  , Adhith Palla  , Alexander Eremiev  , Zachary Sorrentino  , Rasheedat Zakare-Fagbamila  , Jack McNulty  , Carlton Christie  , Vyshak Chandra  and David Mampre

Received: 16 November 2022;  Published: 22 February 2023;  doi: 10.21926/obm.neurobiol.2301158

Reported neuro-modulation schemes in the literature are typically classified as closed-loop or open-loop. A novel group of recently developed neuro-modulation devices may be better described as a neural bypass, which attempts to transmit neural data from one location of the nervous system to another. The most common form of neural bypasses in the literature utilize EEG recordings of cortical information paired with functional electrical stimulation for effector muscle output, most commonly for assistive application [...]

by Sai Batchu  , Michael Joseph Diaz  , Keldon Lin  , Namrata Arya  , Karan Patel  and Brandon Lucke-Wold

Received: 04 September 2022;  Published: 20 February 2023;  doi: 10.21926/obm.neurobiol.2301157

Pituitary neuroendocrine tumors (PitNETs) are common intracranial tumors comprising numerous subtypes whose metabolic profiles have yet to be fully examined. The present in silico study analyzed single-cell expression profiles from 2311 PitNET cells from various lineages and subtypes to elucidate differences in metabolic activities. Gonadotroph tumors exhibited high activities with histidine metabolism, whose activity is low in lactotroph tumors. Somatotroph tumors enriched for sulfur and tyrosine metabolism, while [...]

by Igor Val Danilov

Received: 25 October 2022;  Published: 17 February 2023;  doi: 10.21926/obm.neurobiol.2301156

The article discusses a definition of shared intentionality that reflects recent discoveries for inspiring further translational research in developing bioengineering systems based on human-computer interaction. The child's cognition begins through shared intentionality that occurs in child-caregiver interaction when communication via sensory cues is impossible. There needs to be more knowledge on how it appears. This article argues that shared intentionality is collaborative interactions in which participants shar [...]

by Laura Ryan  , Harriet Beer  , Ella Thomson  , Edward Philcox  and Clive Kelly

Received: 04 October 2022;  Published: 16 February 2023;  doi: 10.21926/obm.neurobiol.2301155

Chronic musculoskeletal pain is an increasingly frequent feature in young people. Many exhibit a range of additional physical and psychological features and fulfil criteria for fibromyalgia. Hypermobility, irritable bowel syndrome and migraine are frequent comorbid conditions. These are all in part mediated by dysfunction of the autonomic nervous system and commonly include fatigue, poor sleep and brain fog. Anxiety, social withdrawal and a range of autistic traits are frequently described by those with chronic mus [...]

by Addisu Yeshambel  , Tamiru Alene  , Getachew Asmare  , Gedion Asnake  , Wallilign Anmut  , Kelemu Abebe  and Belete Birhan

Received: 08 December 2022;  Published: 12 February 2023;  doi: 10.21926/obm.neurobiol.2301154

Perinatal loss is the most painful and unanticipated experience for those who conceived and it is a major global concern worldwide, especially in developed countries like Ethiopia. Women who lost their pregnancy are believed to be at higher risk of developing severe grief following a loss. To reduce the risk of complications after perinatal loss, healthcare providers need to appreciate the grieving process and identify grief factors in mothers for early copying and to be managed promptly by providing adequate emoti [...]

by Sai Batchu  , Michael J. Diaz  , Lauren Ladehoff  and Brandon Lucke-Wold

Received: 27 September 2022;  Published: 03 February 2023;  doi: 10.21926/obm.neurobiol.2301153

Genes encoding for proteins associated with the plasma membrane, referred to as the membranome, have long been recognized to play an important role in the development and maintenance of glioblastoma multiforme (GBM). GBM cell lines are commonly used to mimic tumors for in vitro experiments, but the extent to which they resemble GBM tumors in relation to the membranome is unclear. The present study explores the resemblance of GBM cell lines to primary tumors regarding membranome expression. Gene expression data was [...]