by Giacinto Libertini

Received: 22 July 2022;  Published: 14 October 2022;  doi: 10.21926/obm.geriatr.2204208

The interpretation of aging as an adaptive and programmed phenomenon implies the existence of specific genetically determined and regulated aging-causing mechanisms. This interpretation is in contrast to the explanation of aging as the gradual accumulation of the effects of harmful factors that are only partially countered by natural selection. The subtelomere–telomere theory of aging offers what is required by the interpretation of aging as a programmed phenomenon. The experimentally documented mechanisms that are [...]

by OBM Geriatrics Editorial Office

Received: 09 October 2022;  Published: 09 October 2022;  doi: 10.21926/obm.geriatr.2204207

Open AccessOBM GeriatricsInterviewAn Interview with Dr. David G. SmithardOBM Geriatrics Editorial OfficeLIDSEN Publishing Inc., 2000 Auburn Drive, One Chagrin Highlands, Suite 200, Beachwood, OH, USA; E-Mail: geriatrics@lidsen.comOBM Geriatrics 2022, volume 6, issue 4 doi:10.21926/obm.geriatr.2204207Received: October 09, 2022Accepted: October 09, 2022Published: October 09, 2022

by Dean M. Cordingley  and Stephen M. Cornish

Received: 30 May 2022;  Published: 07 October 2022;  doi: 10.21926/obm.geriatr.2204206

Myokines are cytokines secreted from muscle during contraction and are implicated in autocrine, paracrine, and endocrine regulation of biological systems. It is postulated that myokines contribute to skeletal muscle adaptations in response to resistance exercise. Exercise, including resistance exercise, is an important factor in the management of maintaining skeletal muscle strength, mass, and function with aging. Sarcopenia is exacerbated with increased age and therefore, it is important to understand the potentia [...]

by James S. Powers  , Shana Atkins  and Allison B. McCoy

Received: 05 June 2022;  Published: 28 September 2022;  doi: 10.21926/obm.geriatr.2203205

Many health systems have joined the Age-Friendly Health Systems movement to provide every older adult safe, high-quality care aligned with what matters most. Becoming an Age-Friendly Health System means that hospitals and health care systems reliably use a set of evidence-based practices known as the “4M’s” – What Matters, Medication, Mentation, and Mobility – to provide care for older, disabled and medically complex patients across all care settings. Implementing the Institute for Healthcare Improvement’s (IHI) 4M [...]

by Roy G Beran

Received: 01 July 2022;  Published: 13 September 2022;  doi: 10.21926/obm.geriatr.2203204

This paper examines sleep disorders in older people, focusing on Parkinson’s disease (PD). It defines PD and explores those conditions associated with sleep disorders and their relationship to PD. It identifies specific conditions which cause sleep disoders in patients with PD, namely: REM sleep behaviour disorder (RDB) which may be a precursor to PD; obstructive sleep apnoea (OSA) which is very prevalent amongst people with PD; depression and mood disorders which both increase with age and are more common in peopl [...]

by Kimberly Bader  , James J. Lah  , Allan I. Levey  , Greg J. Esper  , Whitney Wharton  and Joe R. Nocera

Received: 27 December 2021;  Published: 08 September 2022;  doi: 10.21926/obm.geriatr.2203203

Individuals with Alzheimer’s disease (AD) and Mild Cognitive Impairment (MCI) have increased gait disturbances throughout disease progression. However, an understanding of gait impairment and progression in early versus late AD is lacking. Further, the longitudinal progression of gait impairment in AD as well as in those with MCI that transition to AD is lacking. Understanding gait pathology and progression of gait impairment is critical for implementation of strategies that could limit the high prevalence of gait [...]

by Zsuzsanna M. Schmidt  and Gyula Poor

Received: 07 May 2022;  Published: 27 July 2022;  doi: 10.21926/obm.geriatr.2203202

Polymyalgia rheumatica (PMR) is an age-related chronic inflammatory disease with rheumatic features at the fore. In addition to the high-grade systemic inflammation, it is characterized by typical "polymyalgic" musculoskeletal symptoms, including diffuse and severe pain and prolonged morning stiffness of the shoulder girdle, pelvic girdle, and neck. PMR is a member of the so-called giant cell arteritis complex; however, in spite of the marked systemic inflammation in PMR, the local vasculitis process aborts. The pa [...]

by OBM Geriatrics Editorial Office

Received: 01 July 2022;  Published: 03 July 2022;  doi: 10.21926/obm.geriatr.2203201

by Giuseppe Cocco  and Stefano Pandolfi

Received: 07 February 2022;  Published: 16 June 2022;  doi: 10.21926/obm.geriatr.2202200

Syncope is characterized by a transient and rapid loss of consciousness for a short duration, with full spontaneous recovery within minutes. Syncope causes up to 2% of all emergency medical consultations. The incidence of syncope is similar in men and women, is higher in old patients (slightly higher in old women). The prevalence of syncope is up to 23% for the institutionalized elderly. In elderly patients, syncope often presents atypically, such as with falls; these patients might also have difficulty recalling e [...]

by OBM Geriatrics Editorial Office

Received: 01 June 2022;  Published: 09 June 2022;  doi: 10.21926/obm.geriatr.2202199

InterviewAn Interview with Dr. Carlo PedrolliOBM Geriatrics Editorial OfficeLIDSEN Publishing Inc., 2000 Auburn Drive, One Chagrin Highlands, Suite 200, Beachwood, OH, USA; E-Mail: geriatrics@lidsen.comOBM Geriatrics 2022, volume 6, issue 2 doi:10.21926/obm.geriatr.2202199Received: June 01, 2022Accepted: June 02, 2022Published: June 09, 2022