Open Access Review

Volunteer Stem Cell Donor Registries: Global Evolution and the Indian Perspective

Received: 24 March 2026;  Published: 30 July 2026;  doi: 10.21926/obm.transplant.2603272

Abstract

Hematopoietic stem cell transplantation (HSCT) offers a potentially curative option for a range of malignant and non-malignant hematological disorders. However, only approximately 25-30% of patients have access to a human leukocyte antigen (HLA)-matched related donor (MRD), necessitating alternative donor approaches, including matched unrelated donor (MUD) and haploidentical transplantation. Although advances in haploidentical HSCT have substantially improved donor availability, MUD HSCT continu [...]