by Amitha Banu S.  and Khan Sharun

Received: 25 May 2023;  Published: 02 June 2023;  doi: 10.21926/obm.transplant.2302187

Platelet-rich plasma (PRP) is a promising tool in regenerative medicine because it stimulates tissue repair and regeneration. PRP contains a high concentration of platelets, growth factors, and cytokines involved in the healing process. This editorial paper aims to give an overview of PRP in regenerative medicine and its potential applications in various medical fields such as orthopedics, dentistry, dermatology, and wound healing. PRP can be integrated with other regenerative therapies, such as [...]

by Atena Samarehfekri  , Mohammad Ali Zakeri  , Hemn Kaka Mirza  , Adnan Rashid Aziz  and Mahlagha Dehghan

Received: 21 December 2022;  Published: 02 June 2023;  doi: 10.21926/obm.transplant.2302186

Foot reflexology has improved numerous physical and psychological symptoms in patients. The researchers in this study aimed to investigate the effect of foot reflexology on laboratory parameters, intake/output/weight and medication regimen after kidney transplant surgery. The research was a secondary analysis of a parallel randomized controlled trial. The research included patients who were admitted to the transplantation ward. The stratified randomization approach divided 53 eligible patients i [...]

by Rouvick M Gama  , Mysore Phanish  , Abbas Ghazanfar  and Debasish Banerjee

Received: 09 January 2023;  Published: 23 May 2023;  doi: 10.21926/obm.transplant.2302185

Despite preventative measures, including vaccination, severe acute respiratory syndrome coronavirus (SARS-CoV-2) infection may result in severe illness, particularly in immunosuppressed transplant recipients. This has had a negative impact on organ donation and transplantation rates. However, the risk of transmission from SARS-CoV-2 positive donors to kidney transplant recipients is unknown. We describe 2 cases of successful kidney transplantation from SARS-CoV-2 positive donors. Case 1: 38-year [...]

by R. Paul Robertson

Received: 13 February 2023;  Published: 17 May 2023;  doi: 10.21926/obm.transplant.2302184

Pancreatic islet transplantation (ITx) has moved from the experimental phase of development to a position of an accepted and appropriate procedure to apply in clinical medicine. The primary indication for use of ITx is for management of dangerous and recurrent hypoglycemia secondary to use of exogenous insulin for management of hyperglycemia in people with type 1 diabetes. ITx involves procurement of a pancreas donated by a person who has died. The organ is taken to a specialized laboratory for [...]

by Rhythm Joshi  , Zehva Khan  , Aakriti Garg  , Dinesh Bhurani  , Nidhi B Agarwal  , Ubada Aqeel  and Mohd Ashif Khan

Received: 30 September 2022;  Published: 25 April 2023;  doi: 10.21926/obm.transplant.2302183

by Amer Belal  , Shawna Lord  , Rohan Mehta  and Alfonso Santos

Received: 28 October 2022;  Published: 19 April 2023;  doi: 10.21926/obm.transplant.2302182

Cryptococcosis is a common invasive fungal infection in solid organ transplant recipients (SOTR) that can be challenging to manage. We discuss a case of disseminated cryptococcosis in a transplant recipient. A 26-year-old woman with a history of ESRD from C1q nephropathy, living-related kidney transplant in early 2012, and allograft nephrectomy in 2015, received a deceased donor kidney transplant (DDKT). Induction after the first transplant was anti-thymocyte globulin (ATG) and maintenance immun [...]

by Kristen R Szempruch  , Alec D Martschenko  , Harendra Arora  , Robert S Isaak  , Ravindra Prasad  , John L Schmitz  , Chuning Liu  , Fei Zou  and Pablo Serrano Rodriguez

Received: 13 February 2023;  Published: 18 April 2023;  doi: 10.21926/obm.transplant.2302181

Fluid management intra- and post-operatively for kidney transplant recipients (KTR) is essential to maintain adequate perfusion to the kidney. 0.9% normal saline (NS) is commonly used, but it can cause hyperchloremic metabolic acidosis, which may result in hyperkalemia and lead to delayed graft function (DGF). Plasma-Lyte A (PA) is an alternative option that has a lower amount of chloride and a neutral pH, which may offset the risk of hyperkalemia. The aim of this study is to determine the incid [...]

by Michelle N. Bremer  , Garrick J. Gama  , Omkar Rao  , Eugene Golts  , Deepa Kurup  , Aarya Kafi  , Christine M. Lin  , Gordon Yung  and Kamyar Afshar

Received: 28 November 2022;  Published: 10 April 2023;  doi: 10.21926/obm.transplant.2302180

Race, while a social construct, has a strong effect on a person’s health. There is limited data on racial disparities within lung transplantation (LTx), especially for Hispanic recipients. Therefore, the aim of this study was to identify inequalities that may involve this population. We analyzed historical data from the Organ Procurement and Transplantation Network (OPTN) and performed a retrospective review of Hispanic and Caucasian patients who underwent lung transplantation in the United Stat [...]

by Suresh Keshavamurthy  and Cody Russell

Received: 11 January 2023;  Published: 04 April 2023;  doi: 10.21926/obm.transplant.2302179

A boundless spectrum of chronic lung diseases is said to effect over 500 million persons globally. Lung transplantation is a well-established therapeutic option for patients suffering from end-stage lung diseases, however waitlist mortality and primary graft failure remain major determinants as post-transplantation 5-year survival is just above 50 percent. Recent innovations in lung transplantation have been aimed at increasing organ availability, improving allograft quality, function, and longe [...]