Table of Contents

Volume 7,Issue 2

Open Access Editorial

Prospects of Platelet-Rich Plasma in Regenerative Medicine

Received: 25 May 2023;  Published: 02 June 2023;  doi: 10.21926/obm.transplant.2302187


Platelet-rich plasma (PRP) is a promising tool in regenerative medicine because it stimulates tissue repair and regeneration. PRP contains a high concentration of platelets, growth factors, and cytokines involved in the healing process. This editorial paper aims to give an overview of PRP in regenerative medicine and its potential applications in various medical fields such as orthopedics, dentistry, dermatology, and wound healing. PRP can be integrated with other regenerative therapies, such as [...]

Open Access Original Research

Effect of Foot Reflexology on Laboratory Tests after Kidney Transplantation Surgery: A Secondary Analysis of a Parallel Randomized Controlled Trial Study

Received: 21 December 2022;  Published: 02 June 2023;  doi: 10.21926/obm.transplant.2302186


Foot reflexology has improved numerous physical and psychological symptoms in patients. The researchers in this study aimed to investigate the effect of foot reflexology on laboratory parameters, intake/output/weight and medication regimen after kidney transplant surgery. The research was a secondary analysis of a parallel randomized controlled trial. The research included patients who were admitted to the transplantation ward. The stratified randomization approach divided 53 eligible patients i [...]

Open Access Case Report

Successful Kidney Transplantation of Two Patients with Donors Positive for Severe Acute Respiratory Syndrome Coronavirus Infection

Received: 09 January 2023;  Published: 23 May 2023;  doi: 10.21926/obm.transplant.2302185


Despite preventative measures, including vaccination, severe acute respiratory syndrome coronavirus (SARS-CoV-2) infection may result in severe illness, particularly in immunosuppressed transplant recipients. This has had a negative impact on organ donation and transplantation rates. However, the risk of transmission from SARS-CoV-2 positive donors to kidney transplant recipients is unknown. We describe 2 cases of successful kidney transplantation from SARS-CoV-2 positive donors. Case 1: 38-year [...]

Open Access Short Review

Brief Review: Pancreatic Islet Transplantation for Type 1 Diabetes in Humans

Received: 13 February 2023;  Published: 17 May 2023;  doi: 10.21926/obm.transplant.2302184


Pancreatic islet transplantation (ITx) has moved from the experimental phase of development to a position of an accepted and appropriate procedure to apply in clinical medicine. The primary indication for use of ITx is for management of dangerous and recurrent hypoglycemia secondary to use of exogenous insulin for management of hyperglycemia in people with type 1 diabetes. ITx involves procurement of a pancreas donated by a person who has died. The organ is taken to a specialized laboratory for [...]

Open Access Research Article

Short-Term Impact of Hematopoietic Stem Cell Transplantation in Leukemia Patients on Bone Bio Markers, Electrolytes and Blood Profile

Received: 30 September 2022;  Published: 25 April 2023;  doi: 10.21926/obm.transplant.2302183


Hematopoietic stem cell transplantation (HSCT) or Bone Marrow Transplantation (BMT) has significantly improved the survival rates of patients suffering from hematological malignancies. However, the cure can only be achieved at the price of morbidity and long-term complications such as bone diseases leading to fractures and osteopenia. Several studies have reported the impact of organ transplants on bone metabolism, electrolytes and blood profile.

Open Access Case Report

A Case of Disseminated Cryptococcus Post-Kidney Transplant

Received: 28 October 2022;  Published: 19 April 2023;  doi: 10.21926/obm.transplant.2302182


Cryptococcosis is a common invasive fungal infection in solid organ transplant recipients (SOTR) that can be challenging to manage. We discuss a case of disseminated cryptococcosis in a transplant recipient. A 26-year-old woman with a history of ESRD from C1q nephropathy, living-related kidney transplant in early 2012, and allograft nephrectomy in 2015, received a deceased donor kidney transplant (DDKT). Induction after the first transplant was anti-thymocyte globulin (ATG) and maintenance immun [...]

Open Access Original Research

Normal Saline vs Plasma-Lyte A Use Intra- and Post-Operatively in Adult Kidney Transplant Recipients

Received: 13 February 2023;  Published: 18 April 2023;  doi: 10.21926/obm.transplant.2302181


Fluid management intra- and post-operatively for kidney transplant recipients (KTR) is essential to maintain adequate perfusion to the kidney. 0.9% normal saline (NS) is commonly used, but it can cause hyperchloremic metabolic acidosis, which may result in hyperkalemia and lead to delayed graft function (DGF). Plasma-Lyte A (PA) is an alternative option that has a lower amount of chloride and a neutral pH, which may offset the risk of hyperkalemia. The aim of this study is to determine the incid [...]

Open Access Original Research

Robust Outcomes for Hispanic Lung Transplant Recipients in the United States

Received: 28 November 2022;  Published: 10 April 2023;  doi: 10.21926/obm.transplant.2302180


Race, while a social construct, has a strong effect on a person’s health. There is limited data on racial disparities within lung transplantation (LTx), especially for Hispanic recipients. Therefore, the aim of this study was to identify inequalities that may involve this population. We analyzed historical data from the Organ Procurement and Transplantation Network (OPTN) and performed a retrospective review of Hispanic and Caucasian patients who underwent lung transplantation in the United Stat [...]

Open Access Review

A Breath of Fresh Air - Lung Transplantation Has Come of Age

Received: 11 January 2023;  Published: 04 April 2023;  doi: 10.21926/obm.transplant.2302179


A boundless spectrum of chronic lung diseases is said to effect over 500 million persons globally. Lung transplantation is a well-established therapeutic option for patients suffering from end-stage lung diseases, however waitlist mortality and primary graft failure remain major determinants as post-transplantation 5-year survival is just above 50 percent. Recent innovations in lung transplantation have been aimed at increasing organ availability, improving allograft quality, function, and longe [...]