N-Type Calcium Channels Control GABAergic Transmission in Brain Areas related to Fear and Anxiety
Abstract
(ISSN 2573-4407)
OBM Neurobiology is an international peer-reviewed Open Access journal published quarterly online by LIDSEN Publishing Inc. By design, the scope of OBM Neurobiology is broad, so as to reflect the multidisciplinary nature of the field of Neurobiology that interfaces biology with the fundamental and clinical neurosciences. As such, OBM Neurobiology embraces rigorous multidisciplinary investigations into the form and function of neurons and glia that make up the nervous system, either individually or in ensemble, in health or disease. OBM Neurobiology welcomes original contributions that employ a combination of molecular, cellular, systems and behavioral approaches to report novel neuroanatomical, neuropharmacological, neurophysiological and neurobehavioral findings related to the following aspects of the nervous system: Signal Transduction and Neurotransmission; Neural Circuits and Systems Neurobiology; Nervous System Development and Aging; Neurobiology of Nervous System Diseases (e.g., Developmental Brain Disorders; Neurodegenerative Disorders).
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Special Issue
Synapses and Synaptic Function
Submission Deadline: November 20, 2020 (Open) Submit Now
Guest Editor
Dr. Vito Di Maio
Institute of Applied Science and Intelligent Systems (ISASI) "E. Caianiello" of CNR, Via Campi Flegrei 34, 80078 Pozzuoli (NA), Italy
Research Interests: Synaptic Transmission; Electrophysiology; Neuroal Modeling; Synaptic Modeling; Brain Information Processing; Neural Networks
About this topic
The Brain is the largest computational device the humans can imagine with the ability to manage and elaborate the information arriving from the environment as well as from the internal of the body producing the appropriate outputs. The neurons, organized in specialized neural networks, are the building blocks and the elaborators in parallel of all the inputs. Synapses are the devices they use both to receives and send information from/o other neurons in the network. The synapses are, then, the key elements for the understanding of the brain activity and of almost all the pathologies associated with brain malfunctioning. Because of the synaptic dimensions and for several technical limitations, the study of the synaptic functions can be effective only by a multidisciplinary approach.
The present special topic is intended to host papers on synapses and the synaptic function presenting results obtained with by any possible experimental, theoretical and computational approach. Also review showing a wide area of the synaptic functionality or short communications stressing specific problems, or showing preliminary results, are welcome.
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Publication
N-Type Calcium Channels Control GABAergic Transmission in Brain Areas related to Fear and Anxietyby
Maxwell Blazon
,
Brianna LaCarubba
,
Alexandra Bunda
,
Natalie Czepiel
,
Laura Londrigan
,
Shayna Mallat
and
Arturo Andrade
Abstract N-type (CaV2.2) calcium channels are key for action potential-evoked transmitter release in the peripheral and central nervous system. Previous studies have highlighted the functional relevance of N-type calcium channels at both the peripheral and central level. In the periphery, N-type calcium channels regulate nociceptive and sympathetic [...] |
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